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Diss Factsheets
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EC number: 700-839-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20.04.2016-20.07.2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 5-2-A
- Expiration date of the lot/batch: 14. Feb. 2017
- Purity test date: not stated
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: 17 - 23.3 °C, dry conditions, air tight, dark
- Stability under test conditions: stable
- Solubility and stability of the test substance in the solvent/vehicle: assumed stable
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: assumed stable
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: none
- Preliminary purification step (if any): none
- Final dilution of a dissolved solid, stock liquid or gel: none
- Final preparation of a solid: none
FORM AS APPLIED IN THE TEST (if different from that of starting material)
OTHER SPECIFICS: - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- Activated sludge from a biologic sewage treatment plant (predominantly domestic).
Date of collection 24. Jun. 2016
Pretreatment: The sludge was filtrated, washed with tap water (2x), then washed with and re-suspended in test medium. It was then aerated until use. The dry matter was determined with 3900 mg suspended solids/L. - Duration of test (contact time):
- ca. 28 d
- Initial conc.:
- ca. 27.2 mg/L
- Based on:
- other: organic carbon/L
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium:
KH2PO4, K2HPO4, Na2HPO4, NH4Cl, CaCl2, MgSO4, FeCl3*6H2O, Na2EDTA
- Additional substrate: none
- Solubilising agent (type and concentration if used): none
- Test temperature: 19.4 - 22.0 °C
- pH: for stock solution set to 7.4
- pH adjusted: no
- CEC (meq/100 g): not stated
- Aeration of dilution water: yes
- Suspended solids concentration: mpt stated
- Continuous darkness: not stated
- Other: n/a
TEST SYSTEM
- Culturing apparatus: 2000 ml flask
- Number of culture flasks/concentration: 1
- Method used to create aerobic conditions: aeration with purified, CO2-scrubbed, moistened air.
- Method used to create anaerobic conditions: n/a
- Measuring equipment: Data logger for temperature, Carbon analyser, pH-meter
- Test performed in closed vessels due to significant volatility of test substance: no
- Test performed in open system: no
- Details of trap for CO2 and volatile organics if used: CO2 trapped in 0.25 M NaOH
- Other:
SAMPLING
- Sampling frequency: on days 0, 2, 4, 7, 9, 11, 14, 18, 23, 29
- Sampling method: 1 mL by pipette, duplicate or triplicate measurement using the carbon analyser
- Sterility check if applicable: no
- Sample storage before analysis: not stated
- Other:
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: yes
- Toxicity control: yes
- Other:
STATISTICAL METHODS: none applied - Reference substance:
- aniline
- Preliminary study:
- not performed
- Test performance:
- Temperature range was 19.4 - 22 °C instead of 20 - 24 °C. As all validity criteria were fulfilled, this deviation is considered as uncritical concerning the outcome of the study.
- Parameter:
- % degradation (CO2 evolution)
- Value:
- -0.4
- Sampling time:
- 2 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0.1
- Sampling time:
- 4 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 4.9
- Sampling time:
- 7 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 20.9
- Sampling time:
- 9 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 35.6
- Sampling time:
- 11 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 42.9
- Sampling time:
- 14 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 54.7
- Sampling time:
- 18 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 65.1
- Sampling time:
- 23 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 75.2
- Sampling time:
- 29 d
- Details on results:
- Salacos 13 is considered as readily biodegradable.
The degree of biodegradation reached 75 % after 28 days.
The 10-day-window began on day 8, at its end, 55 % degradation were reached, missing the pass level of 60 % given in the OECD guideline.
Because the test item is a Multi-constituent substance and therefore comparable to a mixture, the 1ß-day window has not to be taken into account. Degradation surpassed 60 % within 28 days.
Therefore, the test item is considered as readily biodegradable within 28 days.
Abiotic degradation was not observed.
Validity:
All validity parameters and values are fulfilled:
see table below - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Degradation of Salacos 13 surpasses 60 % within 28 days and the substance can be seen as mixture. Therefore, Salacos 13 is considered as readily biodegradable.
- Executive summary:
The test item Salacos 13 was tested using a concentration of nominally 20 mg organic carbon/L
(corresponding to 26.9 mg Salacos 13/L) in test medium following OECD 301B and EU-Method C.4 -C.
Aniline was chosen as positive control. Activated sludge was used as inoculum (concentration in the test
25.0 mg dry matter/L). The test was left running for 28 days.
All validity criteria were met. Degradation of the positive control was 66 % after 9 days.
The following data were determined for the test item Salacos 13:
10 -day-window: day 8 -18
degradation at the end of 10-day-window: 55 %
degradation at the end of the test: 75 %
pass level following guideline: 60 % at the end of 10-day-window for pure substances respective
60 % at the end of the test for mixtures
Because the test item is a Multi-constituent Substance and therefore comparable to a mixture, the 10 -day-window has not to be taken into account. As degradation surpassed 60 % in the course of the test, Salacos 13 is considered as readily biodegradable.
Reference
Validity results
Parameter | Criterion | Found | Assessment |
IC content of test item solution in medium | <= 5 % of TC | 0 % | valid |
CO2 emitted by the controls | < 70 mg/L | 9.7 mg/L | valid |
Difference within replicates | <= 20 % | 4.7 % | valid |
Degradation of positive control | <= 14 days | 9 days | valid |
Degradation in the toxicity flask on day 14 | > 25 % | 61 % | valid |
Description of key information
one available Guideline study present
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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