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EC number: 643-080-8 | CAS number: 24389-25-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Principles of method if other than guideline:
- - Principle of test:
The objective of the study was to determine the water solubility of the test substance "Phosphorodifluoric acid, lithium salt" for regulatory purposes. For the complete test substance no single analytical method is available. The water solubility was therefore estimated by analysis of the elements lithium and phosphorus.
The solubility of a chemical in water is defined as the saturation mass concentration of the chemical in water and is a function of the temperature.
- Short description of test conditions, parameters analysed / observed:
The principle of the flask method is to disperse about the amount of five times the expected saturation concentration of the test substance in water at least at 10°C and 20°C. When saturation is achieved, the mass concentration of the elements lithium and phosphorous in the aqueous solution, which must not contain any undissolved particles, is determined by inductively coupled plasma atomic emission spectrometry (ICP-AES). - GLP compliance:
- yes
- Type of method:
- flask method
- Water solubility:
- 907 g/L
- Conc. based on:
- element
- Remarks:
- LIthium
- Incubation duration:
- 6 d
- Temp.:
- 10 °C
- pH:
- 0.5 - 1.3
- Water solubility:
- 928 g/L
- Conc. based on:
- element
- Remarks:
- Phosphorus
- Incubation duration:
- 6 d
- Temp.:
- 10 °C
- pH:
- 0.5 - 1.3
- Key result
- Water solubility:
- 917 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- 6 d
- Temp.:
- 10 °C
- pH:
- 0.5 - 1.3
- Details on results:
- Results for the test are recorded in the table above conducted at 10°C. It was not possible to determine the water solubility at 20°C or 30°C as the substance hydrolysed to form hydrogen fluoride which reacted with the glassware and lithium fluoride is precipitated causing loss of the lithium from the solution.
- Conclusions:
- The water solubility of the test substance was determined to be ca. 917 g/L at 10°C using the flask method.
Reference
Description of key information
In an OECD guideline, GLP-compliant study using the shake flask method, the water solubility the test item was determined to be 917 g/L at 10°C.
Key value for chemical safety assessment
- Water solubility:
- 917 g/L
- at the temperature of:
- 10 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.