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EC number: 261-619-1 | CAS number: 59130-69-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Refer to analogue justification provided in IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 3 h
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks on result:
- other:
- Remarks:
- Source: 90411-68-0, Lasem, 2014, respiration inhibition 3h
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks on result:
- other:
- Remarks:
- Source: 90411-68-0, Lasem, 2014, respiration inhibition 3h
Reference
Description of key information
No effects up to the limit of water solubility (OECD 209); read-across
Key value for chemical safety assessment
Additional information
There is no study available, in which the toxicity of the target substance hexadecyl 2-ethylhexanoate (CAS 59130-69-7) to microorganisms was assessed. Therefore, read-across to the structurally related source substance Hexanoic acid, 2-ethyl-, C16-18 alkyl esters (CAS 90411-68-0) was conducted in accordance with Regulation (EC) No 1907/2006 Annex XI, 1.5. The source substance is characterized by similar fatty acid chain lengths as well as alcohol components as the target substance and is therefore considered a suitable representative for the assessment of the toxicity of the target substance to microorganisms. A detailed read-across justification is provided in the analogue justification in IUCLID section 13.
The available study with source substance Hexanoic acid, 2-ethyl-, C16-18 alkyl esters (CAS 90411-68-0) was conducted according to OECD 209 and GLP. Activated sludge was exposed to 10, 100 and 1000 mg/L test item for 3 h. The respiration of the inoculum was not affected, resulting in an EC50 (3 h) of > 1000 mg/L and a NOEC (3 h) of ≥ 1000 mg/L. Therefore, Hexanoic acid, 2-ethyl-, C16-18 alkyl esters is not toxic to microorganisms.
Based on the structural and chemical similarity of the target and source substances, the target substance is expected to exhibit a similar ecotoxicological profile. Therefore, it can be concluded that hexadecyl 2-ethylhexanoate (CAS 59130-69-7) is not toxic to microorganisms up to the limit of water solubility and the degradation in sewage treatement plants is not considered to be inhibited.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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