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EC number: 259-869-1 | CAS number: 55860-53-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- other: published data
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- 2-methylpropan-1-ol (Isobutyl alcohol ) is both reagents used in the manufacture of O-isobutyl ethylthiocarbamate . Therefore, the Biodegradation in water of Isobutyl alcohol need to be considered in the assessment of O-isobutyl ethylthiocarbamate
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- Principles of method if other than guideline:
- Coarse-filtered mixture of domestic treatment plant effluents and rich soil microorganisms were added to BOD dilution water at a concentration of 0.1
mL per liter. BOD dilution water is fortified with specified minerals and buffered to pH 7.2. Seven BOD bottles were prepared with and without test
substance added. One was measured for DO immediately and duplicate bottles measured at days 5, 15, and 28 using a YSI dissolved O2 meter.
Bottles were incubated at 20° C. DO measurements for the test and standard substance (ethylene glycol) were corrected for the blank values. - GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: seed (settled sewage-treated effluent, or commercial Polyseed BOD seed)
- Details on inoculum:
- Coarse-filtered mixture of domestic treatment plant effluents and rich soil microorganisms were added to BOD dilution water at a concentration of 0.1 mL per liter.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 2 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- - Sealed 300 ml bottle
- Temperature 20°C
- BOD dilution water is fortified with specified minerals and buffered to pH 7.2.
- Seven BOD bottles were prepared with and without test substance added.
- One was measured for DO immediately and duplicate bottles measured at days 5, 15, and 28 using a YSI dissolved 02 meter.
- Bottles were incubated at 20 °C.
- DO measurements for the test and standard substance (ethylene glycol) were corrected for the blank values. - Reference substance:
- not specified
- Parameter:
- % degradation (O2 consumption)
- Value:
- > 70 - < 80
- Sampling time:
- 28 d
- Details on results:
- Kinetic of test substance (in %):
= 14 after 5 day(s)
= 74 after 28 day(s) - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- 2-methylpropan-1-ol (Isobutyl alcohol ) is both reagents used in the manufacture of O-isobutyl ethylthiocarbamate . The ready biodegradability of the substance was examined. After 28 days, approximately 74% of the test material was degraded.
Therefore, the Biodegradation in water of Isobutyl alcohol need to be considered in the assessment of O-isobutyl ethylthiocarbamate
These results suggest that O-isobutyl ethylthiocarbamate will be readily biodegradable and it is not expected to persist in the environment. - Executive summary:
2-methylpropan-1-ol (Isobutyl alcohol ) is both reagents used in the manufacture of O-isobutyl ethylthiocarbamate .The ready biodegradability of the substance was examined. After 28 days, approximately 74% of the test material was degraded.
Therefore, the Biodegradation in water of Isobutyl alcohol need to be considered in the assessment of O-isobutyl ethylthiocarbamate
These results suggest that O-isobutyl ethylthiocarbamate will be readily biodegradable and it is not expected to persist in the environment.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- other: published data
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- 2-methylpropan-1-ol (Isobutyl alcohol ) is both reagents used in the manufacture of O-isobutyl ethylthiocarbamate . Therefore, the Biodegradation in water of Isobutyl alcohol need to be considered in the assessment of O-isobutyl ethylthiocarbamate
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Principles of method if other than guideline:
- Wastewater from a domestic treatment plant (Marl-West, Germany) were added to BOD dilution water at a concentration of 0.5 mL per liter. BOD dilution water is fortified with specified minerals and buffered to pH 7.2. Replicate BOD bottles were prepared with and without test substance added or with Texapon as a positive control. DO was measured with an O2 meter on days 5, 15, and 30. Bottles were incubated at 20 deg. C. DO measurements in the bottles without any TS showed O2 consumption of 0.9 mg/L (below the maximum desired O2 consumption for blanks of 1.5 mg/L). Percent degradation was calculated as percent theoretical oxygen demand (2.59 mg O2/mg TS).
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: Sewage sludge from a municipal sewage treatment in Marl, Germany, nonacclimated
- Details on inoculum:
- Wastewater from a domestic treatment plant (Marl-West, Germany) were added to BOD dilution water at a concentration of 0.5 mL per liter. BOD dilution water is fortified with specified minerals and buffered to pH 7.2. Replicate BOD bottles were prepared with and without test substance added or with Texapon as a positive control. DO was measured with an O2 meter on days 5, 15, and 30. Bottles were incubated at 20 deg. C. DO measurements in the bottles without any TS showed O2 consumption of 0.9 mg/L (below the maximum desired O2 consumption for blanks of 1.5 mg/L). Percent degradation was calculated as percent theoretical oxygen demand (2.59 mg O2/mg TS).
- Duration of test (contact time):
- 30 d
- Initial conc.:
- 2 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Wastewater from a domestic treatment plant (Marl-West, Germany) were added to BOD dilution water at a concentration of 0.5 mL per liter. BOD dilution water is fortified with specified minerals and buffered to pH 7.2. Replicate BOD bottles were prepared with and without test substance added or with Texapon as a positive control. DO was measured with an O2 meter on days 5, 15, and 30. Bottles were incubated at 20 deg. C. DO measurements in the bottles without any TS showed O2 consumption of 0.9 mg/L (below the maximum desired O2 consumption for blanks of 1.5 mg/L). Percent degradation was calculated as percent theoretical oxygen demand (2.59 mg O2/mg TS).
- Reference substance:
- not specified
- Parameter:
- % degradation (O2 consumption)
- Value:
- 75
- Sampling time:
- 30 d
- Details on results:
- Kinetic of test Subst:
5 day = 55%,
15 day = 73%,
30 days = 75% - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- 2-methylpropan-1-ol (Isobutyl alcohol ) is both reagents used in the manufacture of O-isobutyl ethylthiocarbamate . Therefore, the Biodegradation in water of Isobutyl alcohol need to be considered in the assessment of O-isobutyl ethylthiocarbamate
These results suggest that O-isobutyl ethylthiocarbamate will be readily biodegradable and it is not expected to persist in the environment. - Executive summary:
2-methylpropan-1-ol (Isobutyl alcohol ) is both reagents used in the manufacture of O-isobutyl ethylthiocarbamate . Therefore, the Biodegradation in water of Isobutyl alcohol need to be considered in the assessment of O-isobutyl ethylthiocarbamate
These results suggest that O-isobutyl ethylthiocarbamate will be readily biodegradable and it is not expected to persist in the environment.
- Endpoint:
- biodegradation in water: ready biodegradability
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Referenceopen allclose all
Description of key information
According to “ANNEX IX- STANDARD INFORMATION REQUIREMENTS FOR SUBSTANCES MANUFACTURED OR IMPORTED IN QUANTITIES OF 100 TONNES OR MORE”, a simulation testing on ultimate degradation in surface water, the study does not need to be performed if the substance is ready biodegradable. Isobutyl alcohol is reagents used in the manufacture of O-isobutyl ethylthiocarbamate.Therefore, the Biodegradation in water of Isobutyl alcohol need to be considered in the assessment of O-isobutyl ethylthiocarbamate . The ready biodegradability of the substance was examined. After 28 days, approximately 74% of the test material was degraded.
The results suggest that Isobutyl alcohol is readily biodegradable and therefore O-isobutyl ethylthiocarbamate will be readily biodegradable and it is not expected to persist in the environment. As O-isobutyl ethylthiocarbamate is ready biodegradable a ready biodegradability study does not need to be conducted.
Therefore testing for Biodegradation in water screening tests does not need to be performed.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.