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EC number: 250-078-7 | CAS number: 30168-23-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- The study was conducted between 22 March 1991 and 19 April 1991.
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: GLP study conducted in compliance with OECD Guideline 301B (modified by used of sealed vessels for assessment of volatile substances) without any deviation.
- Remarks:
- All particular details relating to the study set-up and conduct are not fully presented in Final Report, but refer to internal Standard Operating Procedure documents proper to the testing laboratory.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Version / remarks:
- Modified by use of sealed vessels for assessment of volatile substances
- Deviations:
- no
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Dupical
- IUPAC Name:
- Dupical
- Reference substance name:
- R683
- IUPAC Name:
- R683
- Test material form:
- liquid
- Details on test material:
- - Name of test material (as cited in study report): Dupical (Q), code R683
- Substance type: colourless light floral mobile oily liquid
- Physical state: liquid
- Analytical purity: see confidential section
- Impurities (identity and concentrations): see confidential section
- Isomers composition: see confidential section
- Purity test date: see confidential section
- Lot/batch No.: see confidential section
- Expiration date of the lot/batch: see confidential section
- Storage condition of test material: room temperature in the dark
Constituent 1
Constituent 2
- Specific details on test material used for the study:
- Manufacturer's Code.: 631488
Sample Description: colourless light floral mobile oily liquid
Purity (non-GLP): 89.0%
2 Isomers: 43 & 46%
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Secondary effluent from an unacclimatised activated sludge plant secondary effluent at Unilever Research Laboratory North, used at 10% by volume
- Storage conditions/Preparation of inoculum for exposure: Effluent was filtered through a Whatman filter paper to remove coarse particulate matter.
- Concentration of sludge: no data - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 10 mg/L
- Based on:
- other: nominal organic carbon
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: compliant with 1988 OECD Ring Test on the harmonisation of ready biodegradability tests with the following deviation: the ferric chloride stock solution contained 0.25g not 0.2g. The EDTA stock solution contained 0.4g as recommended in 1988 OECD Ring Test and not 0.5g as specified in draft SOP 15801. No effect on the results expected.
- Additional substrate: no
- Solubilising agent (type and concentration if used): no
- Test temperature: 16-22°C on the period
- pH: no data
- pH adjusted: yes, 6.3
- Suspended solids concentration: no data
- Continuous darkness: not stated
TEST SYSTEM
- Number of culture flasks/concentration: 5, except 3 only for the inoculum control
- Method used to create aerobic conditions: stirring
- Method used to create anaerobic conditions: not applicable
- Measuring equipment: Ionics 555 Inorganic Carbon Analyser.
- Test performed in closed vessels due to significant volatility of test substance: yes
- Test performed in open system: no
- Details of trap for CO2 and volatile organics if used: not applicable
SAMPLING
- Sampling frequency: on day numbers, 4, 6, 11, 14, 18, 21, 25 and 28
- Sampling method: Ionics 555 Inorganic Carbon Analyser.
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Toxicity control: no data
Results and discussion
- Preliminary study:
- No data
- Test performance:
- No data
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 5.8
- Sampling time:
- 28 d
- Details on results:
- - % biodegradation on Day 28 = 5.8%, 95% confidence limit [3.3-8.4 %]
BOD5 / COD results
- Results with reference substance:
- no data
Any other information on results incl. tables
Table 1 Percentage biodegradation of test substance
Day No |
% biodegradation(a) |
|
R683 |
4 |
6.1 |
6 |
-1.2 |
11 |
2.5 |
14 |
-0.1 |
18 |
-0.1 |
21 |
-2.8 |
25 |
2.9 |
28 |
5.8 |
95% confid. limit |
3.3 - 8.4 |
(a) Based on nominal carbon concentration assuming 100% purity of the named test substance.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- Under the test conditions, the substance is considered as not readily biodegradable.
- Executive summary:
The biodegradation of Dupical was studied using a sealed vessel that is a CO2 production test based on OECD guideline 301B and studies conducted by the OECD aimed at harmonizing the various tests of ready biodegradability. The test system is closed and is therefore suitable for the examination of volatile materials. Inoculum came from secondary effluent from an unacclimatised activated sludge plant at Unilever Research Laboratory North. Initial nominal concentration of the test substance was 10 mg/l organic carbon. Biodegradation of the test substance is recorded by the evolution of the CO2 during the study. Analysis of both the headspace gas and the liquid medium for CO2/DIC was performed.
Dupical undergoes 5.8% biodegradation after 28 days. Therefore, and in accordance with the OECD Guidelines principles, Dupical is considered as not readily biodegradable. Validity criteria are all met, the study is considered as acceptable for the endpoint.
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