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Diss Factsheets
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EC number: 249-047-0 | CAS number: 28473-19-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
In a GLP study, conducted in accordance with OECD Guideline 105, the water solubility of DIDS was determined to be 0.095 mg/L at 20 °C (Walker, 2013). DIDS can therefore be considered practically insoluble in water.
Key value for chemical safety assessment
- Water solubility:
- 0.095 mg/L
- at the temperature of:
- 20 °C
Additional information
In a GLP study, performed in accordance with OECD Guideline 105, the water solubility of DIDS was determined to be 0.095 mg/L at 20 °C using the flask method (Walker, 2013). DIDS can therefore be considered practically insoluble in water.
In addition, water solubility values of 4.78 x 10-8, 4.83 x 10-7and 3.37 x 10-5 mg/L were predicted for DIDS using the OECD QSAR Toolbox (v.3.0) (OECD, 2012). Water solubility was predicted from Log Kow and fragments (both using EPI Suite (WSKOWWIN)) and Multicase, respectively.
Relevant read-across data:
DIDA was of low solubility when assessed using the slow-stir method in a good quality study. Water solubility was 4.4 x 10-5 mg/L at 20 °C (Letinski et al. 2002).
Very low water solubility has been reported for DEHS by various sources (ACC, 2010; INEOS Enterprises, 2009c).
The low solubility of DIDA and DEHS support their use for read-across purposes for DIDS.
References
INEOS Enterprises (2009c). CEREPLAS™ DOS. Safety Data Sheet. Date 06/2009, rev. 03 (UK03).
Letinski DJ, Connelly MJ Jr, Peterson DR and Parkerton TF (2002). Slow-stir water solubility measurements of selected alcohols and diesters. Chemosphere 48, 257-265 (cited in ACC, 2010).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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