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Diss Factsheets
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EC number: 244-479-6 | CAS number: 21615-47-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Remarks:
- For ammonium perfluorohexanoate (AmPFHX) as CMC (critical micelle concentration)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- CMC by Surface Tension (ring method) vs. Concentration
- GLP compliance:
- no
- Type of method:
- other: CMC by Surface Tension (ring method) vs. Concentration
- Water solubility:
- 174 other: mmol / dm3, same as mmol/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- Remarks on result:
- other: Water solubility is based on CMC.
- Remarks:
- (174 mmol/L = 57,610 mg/L)
Reference
RESULTS
The individual surface tension and concentration results are summarized in the table below. These data were used to create the plot of Surface Tension vs. Concentration; using this plot, the resulting Critical Micelle Concentration (CMC) of APFHx (C-1500N) was determined to be 174 mmol / dm3(182 mmol / kg) at 20 °C.
Molality, m (mmol / kg) |
Density, ρ (g / cm3) |
Molarity, c (mmol / dm3) |
Run # |
Max. force (mgf) |
Correction Factor, F |
Surface Tension (mN/m) |
40.5 |
1.008 |
40.3 |
1 |
646.8 |
0.9182 |
48.9 |
2 |
646.6 |
0.9182 |
48.8 |
|||
Average |
- |
- |
48.8 |
|||
69.4 |
1.014 |
68.8 |
1 |
554.3 |
0.9078 |
41.4 |
2 |
554.0 |
0.9078 |
41.4 |
|||
Average |
- |
- |
41.4 |
|||
125 |
1.025 |
123 |
1 |
443.6 |
0.8926 |
32.6 |
2 |
443.2 |
0.8926 |
32.5 |
|||
Average |
- |
- |
32.6 |
|||
357 |
1.066 |
341 |
1 |
357.0 |
0.8759 |
25.7 |
2 |
357.0 |
0.8759 |
25.7 |
|||
Average |
- |
- |
25.7 |
|||
1088 |
1.138 |
911 |
1 |
333.3 |
0.8671 |
23.8 |
2 |
333.1 |
0.8671 |
23.8 |
|||
Average |
- |
- |
23.8 |
|||
2998 |
1.291 |
1942 |
1 |
304.7 |
0.8526 |
21.4 |
2 |
304.8 |
0.8526 |
21.4 |
|||
Average |
- |
- |
21.4 |
Notes:
Density (ρ) is measured using pycnometer method.
Molarity, c, is calculated from molality (m) and density (ρ) using equation below.
c = (1000*m*ρ) / (1000 + m*M) where M = MW of sample (331.08)
Correction Factor is determined according to Appendix in report.
Accuracy of surface tension result is ± 0.1 to 0.2 mN / m.
Description of key information
Water solubility at 20 ºC is 174 mmol/L (57.61 g/L) as CMC (Critical Micelle Concentration) determined by surface tension vs. concentration.
Key value for chemical safety assessment
- Water solubility:
- 57.61 g/L
- at the temperature of:
- 20 °C
Additional information
Supporting study for Perfluorohexanoic Acid (PFHxA), CAS 307-24-4:
Water solubility at 20 °C is > 250 g/L (OECD 105, flask method), final pH = 0.6.
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