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Diss Factsheets
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EC number: 215-355-9 | CAS number: 1323-42-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 21 March 2017 to 19 April 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- yes
- Remarks:
- The temperatures in a non-test vessel were recorded at 24.8, 24.9 and 24.8 oC on days 19, 25 and 26 of the test, respectively, outside the specified range of 22 ± 2 oC. This deviation did not affect study integrity since all validation criteria were met.
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Version / remarks:
- 440/2008
- Deviations:
- yes
- Remarks:
- The temperatures in a non-test vessel were recorded at 24.8, 24.9 and 24.8 oC on days 19, 25 and 26 of the test, respectively, outside the specified range of 22 ± 2 oC. This deviation did not affect study integrity since all validation criteria were met.
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 835.3110 (Ready Biodegradability)
- Version / remarks:
- The guideline was identified as OCSPP 835.3110 in the study report.
- Deviations:
- yes
- Remarks:
- The temperatures in a non-test vessel were recorded at 24.8, 24.9 and 24.8 oC on days 19, 25 and 26 of the test, respectively, outside the specified range of 22 ± 2 oC. This deviation did not affect study integrity since all validation criteria were met.
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- A mixed population of activated sewage sludge micro-organisms was obtained on 20 March 2017 from the aeration stage of the Severn Trent Water Plc sewage treatment plant at Loughborough, Leicestershire, UK, which treats domestic sewage.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 14.9 mg/L
- Based on:
- test mat.
- Initial conc.:
- 10 mg/L
- Based on:
- TOC
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- The amount of the test item was dispersed directly in mineral medium with the aid of high shear mixing prior to dispersal in inoculated mineral medium. The volume was adjusted to 3 liters to give a final concentration of 14.9 m/L, equivalent to 10 mg carbon/L.
- Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 49
- Sampling time:
- 28 d
- Validity criteria fulfilled:
- yes
- Remarks:
- IC content 0% & 2% (protocol ≤ 5%); CO2 emitted by controls 32.70 mg/L (protocol <70 mg/L; difference replicates less than 20% (protocol ≤20 %); degradation positive control 87% at 14 d (protocol ≤14 d); degradation toxicity d 14, 40% (protocol > 25%).
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The test substance is considered as “not readily biodegradable”. The test substance reached 49% biodegradation after 28 d.
Reference
Description of key information
The key study was a CO2 evolution test conducted in accordance with OECD Guideline 301B. The substance was not found to be readily biodegradable in a test conducted in accordance with OECD Guideline 301B. The biodegradation was reported as 49% after 28 days. Although this level does not show ready biodegradability, it is indicative of inherent primary degradation and substantial mineralisation.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.