Registration Dossier
Registration Dossier
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EC number: 211-425-8 | CAS number: 644-97-3
Endpoint summary
Administrative data
Description of key information
The information on acute toxicity is limited. The substance is highly reactive and releases hydrochloric acid upon contact with water. As such, it is corrosive and the secondary information on an LD50 between 500 and 2000 mg/kg bw plausible.
Key value for chemical safety assessment
Additional information
Secondary information indicates that no mortality occurs upon a single oral exposure of 464, 500 or 1000 mg/kg bw in rats. Mortality in all animals was observed at doses of 2000 mg/kg bw or higher.
No reliable information is available on acute dermal or inhalation toxicity. As the substance is corrosive, this information is not needed.
The substance reacts upon contact with water and releases hydrochloric acid. Local effects are the most prominent effects for this substance.
Justification for classification or non-classification
Dangerous Substance Directive (67/548/EEC)
The available information is of secondary source, and its validity for classification purposes under 67/548/EEC cannot be verified. However, the information appears plausible. As a result the substance is considered to be classified for acute oral toxicity (Xn; R22) under Directive 67/548/EEC, as amended for the 28th time in Directive 2001/59/EC.
Classification, Labelling, and Packaging Regulation (EC) No. 1272/2008
The available information is of secondary source, and its validity for classification purposes under 67/548/EEC cannot be verified. However, the information appears plausible.
As a result the substance is considered to be classified for acute oral toxicity (Acute class 4) under Regulation (EC) No. 1272/2008, as amended for the second time in Directive (EC 286/2011).Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
