Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
203-953-2
CAS no.:
112-27-6
Index number:
Molecular formula:
C6H14O4
SMILES:
OCCOCCOCCO
InChI:
InChI=1S/C6H14O4/c7-1-3-9-5-6-10-4-2-8/h7-8H,1-6H2
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
26
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified.
According to the majority of notifications provided by companies to ECHA in CLP notifications no hazards have been classified.

Breakdown of all 2493 C&L notifications submitted to ECHA

Not Classified
Eye Irrit. 2 H319
Skin Irrit. 2 H315
STOT SE 3 H335
Acute Tox. 4 H332
Acute Tox. 3 H301
Eye Irrit. 2A H319
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 51 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: inks and toners and coating products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, open transfer and processing with minerals/metals at elevated temperature and high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding).

Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), plastic (e.g. food packaging and storage, toys, mobile phones), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), metal (e.g. cutlery, pots, toys, jewellery) and stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material).

This substance is used in the following products: inks and toners and paper chemicals and dyes.

This substance is used in the following areas: printing and recorded media reproduction. This substance is used for the manufacture of: plastic products, chemicals and machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: inks and toners, washing & cleaning products, non-metal-surface treatment products, paper chemicals and dyes and polymers.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, transfer of substance into small containers, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: inks and toners, coating products, polymers, washing & cleaning products and heat transfer fluids. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: mining, formulation of mixtures and/or re-packaging and printing and recorded media reproduction. This substance is used for the manufacture of: chemicals and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, laboratory work and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and for thermoplastic manufacture.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, laboratory work and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • ANTWERP DISTILLATION COMPANY NV, GESLECHT PORT 1931 B-9130 KALLO Belgium
  • B-Lands Consulting (8111117-5), World Trade Center, 5 Place Robert Schuman - BP1510 38025 Grenoble France France
  • BASF Antwerpen N.V., Haven 725, Scheldelaan 600 2040 Antwerpen 4 Antwerpen Belgium
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BCI POLYURETHANE EUROPE SRL, P.le Cocchi 22 (Z.I) 21040 Vedano Olona (VA) Italy
  • BD&I_15, 92 rue Omer Lepreux 1081 Koekelberg Belgium
  • BD&I_37, rue Omer Lepreux, 92 1081 bruxelles Belgium Belgium
  • Cambridge Environmental Assessments, part of RSK ADAS Europe (Ireland) Ltd (MIK), Office Suite B, Bluebell Business Centre Old Naas Road DB12XV7K Dublin Ireland
  • ChampionX Europe B.V., Oude Rhijnhofweg 17 NL-2342BB Oegstgeest Oegstgeest Netherlands
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Speed Infotech (Beihai) Company Limited), Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Clariant Produkte (Deutschland) GmbH, August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany
  • Dow Belgium B.V.B.A., Grotesteenweg 214 B-2600 Antwerpen (Berchem) Belgium
  • ERM_GmbH_OR13_KM, Siemenstrasse 9. 63263 Neu Isenburg Hessen Germany
  • ExponentOR30IRE, Block 1, Blanchardstown Corporate Park D15 AKK1 Dublin Ireland
  • ExxonMobil Petroleum & Chemical BV, Polderdijkweg 2030 Antwerpen Belgium
  • Fujifilm Europe GmbH (OR3), Balcke-Dürr-Allee 6 40882 Ratingen NRW Germany
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17, 22363 Lund Sweden
  • Helm AG, Nordkanalstraße 28 20097 Hamburg Germany
  • HUNTSMAN HOLLAND BV, Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands
  • HVL GmbH, Ernst-Eisenlohr-Str. 14 79410 Badenweiler Germany
  • INDUSTRIAS QUIMICAS DEL OXIDO DE ETILENO, S.A., AVDA. REMOLAR, 2 08820 PRAT DE LLOBREGAT Spain
  • INEOS Manufacturing Deutschland GmbH, Alte Strasse 201 50769 Koeln Germany
  • INEOS nv, Haven 1053 -- Nieuwe Weg 1 2070 Zwijndrecht Belgium
  • ITW Performance Polymers, A Division of ITW Ireland, Bay 150 Shannon Industrial Estate V14 DF82 Shannon Co. Clare Ireland
  • John Dunleavt T/A Waltham Advisory, 45 Waltham Terrace Blackrock A94 K5F7 Dublin Ireland
  • Kodak GmbH, Kesselstrasse 19 70327 Stuttgart Germany
  • Labcorp Development SA 024, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain
  • Labcorp Development SA 104, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain
  • Liquichem Handelsgesellschaft mbH, Kajen 6–8 20459 Hamburg Germany
  • Memjet Limited, Trintech Building South County Business Park, Leopards Town D18 H5H9 Dublin Ireland
  • Merck Schuchardt OHG, Eduard-Buchner-Str. 85662 Hohenbrunn Germany
  • Mitsubishi_Chemical_Europe_GmbH, Schiessstraße 47 40549 Düsseldorf Germany
  • OQ Chemicals GmbH, Rheinpromenade 4a 40789 Monheim NRW Germany
  • Oxiteno Europe OR2, Ikaroslaan 6 1930 Zaventem Belgium
  • Polski Koncern Naftowy ORLEN SA, ul. Chemików 7 09-411 Płock Poland Poland
  • Ramboll Belgium bvba, Meersbloem-Melden 46 9700 Oudenaarde Belgium
  • REACHLaw Ltd, Aleksanterinkatu 19 00100 Helsinki Finland
  • REACHLINKED OÜ, Ahtri tn 12 10151 Tallinn Estonia
  • SABIC Petrochemicals B.V., Europaboulevard 1 6135 LD Sittard Limburg Netherlands
  • Sasol Germany GmbH, Anckelmannsplatz 1 D-20537 Hamburg Germany
  • Shell Chemicals Europe B.V., Weena 505 3013 AL Rotterdam Netherlands Netherlands
  • Shell Nederland Chemie B.V., Chemieweg 25 PO BOX 6060, 4782 SJ Moerdijk Netherlands
  • STEPAN POLSKA, Urazka Street PL 56-120 Brzeg Dolny Poland
  • TÜV SÜD Iberia S.A.U. (049), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • TÜV SÜD Iberia S.A.U. (051), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • TÜV SÜD Iberia, S.A.U. (083), Ronda Can Fatjó, 13 08290 Cerdanyola del Vallès (Barcelona) Spain
  • Yordas GmbH, Äußere Nürnberger Str. 62, 91301 Forchheim Germany
  • [Confidential], [Confidential]
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • Eastman Specialties AS, Uus Tehas 8 30328 Kohtla-Jarve Estonia
  • HML Europe BV, De Haal 82 1511 AT Oostzaan Netherlands
  • Huntsman (Europe) BV - OR5, Everslaan 45 B-3078 Everberg Belgium
  • Petrochemical Commercial Company (UK) Ltd, 24, GROSVENOR GARDENS SW1W 0DH LONDON EUROPE United Kingdom
  • REACH NATION 2, Avenue du Pesage 18, Box 9 1050 Brussels Belgium
  • [Confidential], [Confidential]

Substance names and other identifiers

1,2-Bis(2-hydroxyethoxy)ethane
Other
2,2'-(1,2-Ethanediylbis(oxy))bisethanol
Other
2,2'-(ethylenedioxy)diethanol
EC Inventory, Other
2,2'-(ethylenedioxy)diethanol
REACH pre-registration, Other
2,2'-Ethylenedioxybis(ethanol)
Other
2,2'-Ethylenedioxydiethanol
Other
2,2'-Ethylenedioxyethanol
Other
3,6-Dioxaoctane-1,8-diol
Other
Bis(2-hydroxyethoxyethane)
Other
Di-beta-hydroxyethoxyethane
Other
Ethanol, 2,2'-(1,2-ethanediylbis(oxy))bis-
Other
Ethanol, 2,2'-(ethylenedioxy)di-
Other
Ethylene glycol dihydroxydiethyl ether
Other
Ethylene glycol-bis-(2-hydroxyethyl ether)
Other
Glycol bis(hydroxyethyl) ether
Other
TEG
Other
Triethylene glycol
Other
Triethyleneglycol
FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Recycled Plastic FCMs - Regulation (EU) 2022/1616, Food Contact Regenerated Cellulose Directive - Authorised Substances
Triethylenglykol
Other
Trigen
Other
Triglycol
Other
1,2-bis(2-hydroxyethoxy)ethane
C&L Inventory
2,2'-(ethylenedioxy) diethanol
C&L Inventory
2,2'-(Ethylenedioxy)diethanol
C&L Inventory, Registration dossier
2,2'-(ethylenedioxy)diethanol
C&L Inventory, Registration dossier
2,2'-(etilendioxi)dietanol
C&L Inventory
2,2'-[ethane-1,2-diylbis(oxy)]diethanol
C&L Inventory, Registration dossier
2,2-(ethylenedioxy)diethanol
C&L Inventory
2,2’- {ethane-1,2-diylbis(oxy)}diethanol
Registration dossier
2,2’-[1,2-Ethanediylbis(oxy)]bisethanol
C&L Inventory, Registration dossier
2-[2-(2-hydroxyethoxy)ethoxy]ethan-1-ol
C&L Inventory, Registration dossier, Other
2-[2-(2-Hydroxyethoxy)ethoxy]ethanol
C&L Inventory, Registration dossier, Other
Ethanol, 2,2'-(1,2-ethanediylbis(oxy))bis-
C&L Inventory
Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-
C&L Inventory
not applicable
Registration dossier
TEG
Registration dossier
TRIETHYLENE GLYCOL
C&L Inventory, Registration dossier
Triethylene Glycol
C&L Inventory, Registration dossier
Triethylene Glycol (TEG)
Registration dossier
Triethylene glycol, also known as TEG.
Registration dossier
TRIETHYLENEGLYCOL
C&L Inventory
Triethyleneglycol
C&L Inventory, Registration dossier
Triethylenglykol
Registration dossier
1,2-Bis(2-hydroxyethoxy)ethane
Registration dossier
1,2-Di(β-hydroxyethoxy)ethane
Registration dossier
2,2'-(Ethylendioxy)diethanol
Registration dossier
2,2'-(ethylenedioxy)diethanol
Registration dossier
2,2'-(etilendioxi)dietanol
Registration dossier
2,2'-(éthylenedioxy)diéthanol
Registration dossier
2,2'-[ethane-1,2-diylbis(oxy)]diethanol
Registration dossier
2,2'-Ethylenedioxydiethanol
Registration dossier
2-(2-(2-Hydroxyethoxy)ethoxy)ethanol
Registration dossier
3,6-Dioxaoctane-1,8-diol
Registration dossier
Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-
Registration dossier
Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis- (9CI)
Registration dossier
Ethylene Glycol - DE
Registration dossier
Ethylene Glycol Antifreeze Grade
Registration dossier
Ethylene Glycol Industrial Grade
Registration dossier
Glikol trietylenowy
Registration dossier
Glycol bis(hydroxyethyl) ether
Registration dossier
TEG
Registration dossier
TEG (glycol)
Registration dossier
TEG HP
Registration dossier
Tri Ethylene Glycol
Registration dossier
TRIETHYLENE GLYCOL
Registration dossier
Triethylene glycol (8CI)
Registration dossier
Triethylene glycol (TEG)
Registration dossier
Triethylene Glycol HP
Registration dossier
Triethylene Glycol Technical Grade
Registration dossier
Triethylenglykol
Registration dossier
Triglycol
Registration dossier
Triglykol
Registration dossier
2,2'-(ethylenedioxy)diethanol
REACH pre-registration
Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-
REACH pre-registration
112-27-6
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Recycled Plastic FCMs - Regulation (EU) 2022/1616, Food Contact Regenerated Cellulose Directive - Authorised Substances
118662-30-9
CAS number
Other
121202-29-7
CAS number
Other
676-18-6
CAS number
Other
939972-01-7
CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Liquid (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 3 studies processed
R Melting / freezing point
-9.4 - -4 °C [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-7 °C

Boiling point

Study results
  • 3 studies submitted
  • 1 study processed
R Boiling point
286.5 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
286.5 °C

Density

Study results
  • 3 studies submitted
  • 1 study processed
R Density
1.13 g/cm³ @ 15 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 3 studies submitted
  • 1 study processed
R Vapour pressure
0.066 Pa @ 24.7 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0.066 Pa @ 24.7 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 3 studies processed
R Log Pow
-1.98 - -1.748 @ 25 °C [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
-1.75 @ 25 °C

Water solubility

Study results
  • 3 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
1 000 g/L @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 2 studies processed
R Flash point
176 - 177 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
176 °C

Auto flammability

Study results
  • 2 studies submitted
  • 2 studies processed
R Autoflammability / self-ignition
347 - 370 °C @ 101.3 kPa [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
347 °C

Flammability

Study results
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Not classified (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 3 studies submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
47.8 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
47.8 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 6 studies submitted
  • 1 study processed
R Dissipation half life (DT50)
10.6 h [1]
R Degradation rate constant (OH radicals)
0 cm³ molecule-1 d-1 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1 4
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
10.6 h
Degradation rate constant with OH radicals
0 cm³ molecule-1 d-1

Hydrolysis

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 8 studies submitted
  • 7 studies processed
C Interpretation of results
Readily biodegradable (43%), Readily biodegradable but failing the 10-day window (43%), Inherently biodegradable (14%) [7]

Type of Study provided
Studies with data
Key study 7 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)
Type of water
Freshwater (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 6 studies submitted
  • 1 study processed
R H - (pressure) m³/mol
0 Pa m³/mol @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1 4
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0 Pa.m³.mol-1 @ 25 °C

Distribution modelling

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (1)
Intermittent releases (freshwater) No hazard identified (1)
Marine water No hazard identified (1)
Intermittent releases (marine water) No hazard identified (1)
Sewage treatment plant (STP) No hazard identified (1)
Sediment (freshwater) No hazard identified (1)
Sediment (marine water) No hazard identified (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No hazard identified (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 12 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 10 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2 1
Weight of evidence
Other 3 1 4
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Long–term toxicity to fish

Study results
  • 7 studies submitted
  • 1 study processed
P/RResults
NOEC (28 days) 40 mg/L [2]
LC50 (28 days) 1.5 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 11 studies submitted
  • 3 studies processed
P/RResults
EC50 (48 h) 100 mg/L [1]
LC50 (4 days) 65.98 g/L [1]
LC50 (48 h) 62.63 g/L [1]
EC0 (48 h) 100 mg/L [1]
EC100 (48 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 3 1
Supporting study 1 1
Weight of evidence
Other 1 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 10 studies submitted
  • 2 studies processed
P/RResults
NOEC (23 days) 1 g/L [1]
NOEC (21 days) 7.5 - 15 g/L [2]
EC50 (21 days) 33.911 g/L [1]
LC50 (23 days) 1 g/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 1 1
Weight of evidence
Other 1 1 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 10 studies submitted
  • 2 studies processed
P/RResults
NOEC (72 h) 100 mg/L [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 1 1 1
Weight of evidence
Other 1 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 16 mL/kg bw (rat) [1]
M/CInterpretations of results
GHS criteria not met [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (4 h) 5.2 mg/L air (rat) [1]
M/CInterpretations of results
GHS criteria not met [1]

inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 16 mL/kg bw (rabbit) [1]
M/CInterpretations of results
GHS criteria not met [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed Discriminating dose 18 080 mg/kg bw
Inhalation route:
No adverse effect observed Discriminating conc. 5.2 mg/L air
Dermal route:
No adverse effect observed Discriminating dose 18 080 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 5 studies submitted
  • 4 studies processed
P/RResults
NOAEC (rat): 1 - 1.036 mg/L air [2]
NOAEC (mouse): 1 mg/L air [1]
LOAEC (rat): 494 mg/m³ air [1]

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence 4 1
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 1 522 mg/kg bw/day (subchronic, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 750.865 mg/m³ (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 4 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No study available

Carcinogenicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed NOAEL 1 160 mg/kg bw/day (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study
Weight of evidence 3 1
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 6 780 mg/kg bw/day (subacute, mouse)
Effect on developmental toxicity
Oral route:
Adverse effect observed NOAEL 565 mg/kg bw/day (subacute, mouse)

Neurotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant