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EC number: 401-700-2 | CAS number: 3100-36-5 CYCLOHEXADECENON; CYCLOHEXADECENONE
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1998-06-22 to 1998-07-3
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- other: According to Commission Directive 88/302/EEC, Official Journal of the EC L133, Part C: Biodegradability: Test for inhibition of oxygen consumption
- Version / remarks:
- (correspondings for the most part to the test method OECD 209)
- GLP compliance:
- yes
- Analytical monitoring:
- no
- Remarks:
- The study was carried out with nominal weights. The test concentrations were not confirmed by chemical analysis.
- Vehicle:
- no
- Test organisms (species):
- activated sludge of a predominantly domestic sewage
- Details on inoculum:
- - Laboratory culture: No
- Name and location of sewage treatment plant where inoculum was collected: Wupper area water authority.
- Pretreatment: No - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 h
- Test temperature:
- 19.8 - 20.2 °C
- pH:
- 7.6-7.7
- Dissolved oxygen:
- Control:
Start: 6.0-6.5 mg O2/L; End: 2.6 mg O2/L;
Test solution:
Start: 4.2-5.6 mg O2/L; End: 2.6-2.9 mg O2/L;
Physiochemical oxygen consumpation conctrol (10000 mg/L):
Start: 7.4 mg O2/L; End: 7.4 mg O2/L; - Nominal and measured concentrations:
- Nominal concentrations: 100-1000-10000 mg/L with a test concentration separation factor of 10
- Details on test conditions:
- Not reported in details
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-Dichlorophenol
- Key result
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Details on results:
- See below
- Results with reference substance (positive control):
- - Results with reference substance valid? Yes
- Relevant effect levels: 5-20 mg/L (12.7-83.9% inhibition) - Validity criteria fulfilled:
- yes
- Conclusions:
- The EC50 (3h) of the test item to the respiration of microorganisms was determined to be above 10000 mg/L.
- Executive summary:
The inhibition effect of the test item to the respiration of microorganisms was tested according to Commission Directive 88/302/EEC, Official Journal of the EC L133 part C (similar to OECD 209) and GLP. Three concentrations (100-10000 mg/L) with a separation factor of 10 were tested. The EC50 (3h) of the test item to the respiration of microorganisms was determined to be above 10000 mg/L.
Reference
Inhibition of the test item to the respiration of microorganisms:
Test concentration [mg/L] | Respiratory rate test substance [mg/L*h] | Phys.chem. O2-consumption [mg/L*h] | Respiratory rate -phys. chem. Phys.chem. O2-consumption [mg/L*h] | Inhibition [%] |
100 | 33.6 | 0 | 33.6 | 0 |
1000 | 34.5 | 0 | 34.5 | 0 |
10000 | 32.0 | 0 | 32.0 | 0 |
Control-1 | 29.1 | - | - | - |
Control-2 | 29.3 | - | - | - |
Control-mean | 29.2 | - | - | - |
Phys.chem. O2-consumption is carried out to determine if any oxygen is consumed by chemical reactivity of the test substance.
Description of key information
A study on the inhibition effect of the test item to the respiration of microorganisms was conducted according to Commission Directive 88/302/EEC, Official Journal of the EC L133 part C (similar to OECD 209) and GLP. Three concentrations (100-10000 mg/L) with a separation factor of 10 were tested. The EC50 (3h) of the test item to the respiration of microorganisms was determined to be above 10000 mg/L.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 10 000 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.