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Diss Factsheets
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EC number: 700-903-6 | CAS number: 255830-15-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No toxicity data are currently available for soil microorganisms. The terrestrial chemical safety assessment has been conducted using the Equilibrium Partitioning Method based on the aquatic data set.
Key value for chemical safety assessment
Additional information
In accordance with Column 2 of REACH Annex IX, there is no need to further investigate the effects of this substance in a soil microorganism study because:
• The substance is involatile and highly adsorbing and low toxicity was observed in the available pelagic organism and aquatic microorganism tests, and there is no reason to expect effects in the terrestrial compartment that were not expressed in the aquatic compartment.
• Based on the aquatic data set, the most sensitive relevant trophic level is algae.
• The soil hazard category 3 has been derived for the substance. According to the screening assessment for soil hazard category 3, the PNECsoil has been calculated from PNECfreshwater on the basis of the equilibrium partitioning method and a confirmatory long-term toxicity to terrestrial organisms has been proposed for the ATMP category. The risk characterisation ratio (RCR) based on PNECsoil derived from the equilibrium partitioning method is <1.
• The phosphonate ligand binds strongly and irreversibly to various minerals present in soil and so bioavailability to soil organisms is extremely limited.
The terrestrial chemical safety assessment has been conducted using the Equilibrium Partitioning method (EQPM).
It is recognised that the aquatic PNEC used in the EQPM does not consider any indicator for effects in aquatic microorganisms. However, a number of non-standard studies are available giving evidence that ATMP has no inhibitory effect on micro-organisms at concentrations up to ca. 200 mg/L. A study of seven Swiss WWTPs in 1996 shows a maximum concentration of ATMP in WWTP untreated influent of ca. 0.8 µmol/L, equivalent to ca. 0.26 mg/L. These studies demonstrate the low toxicity of ATMP and its salts to micro-organisms. See Section 6.1.7 for further details.
These results show a lesser level of effect to that observed in the lowest reliable short-term aquatic toxicity study with invertebrates, where a 48-h EC50 value of 94 mg active acid/L with Acartia tonsa was determined (Zeneca, 1995).
The data on long-term ecotoxicity to fish and invertebrates also suggest that aquatic microorganisms are comparatively less sensitive, where the lowest reliable long-term toxicity NOEC value was observed with fish at 23 mg active acid/L (ABC, 1980).
Therefore it is unlikely that the PNECterrestrial based on aquatic ecotoxicity test results would not be protective for terrestrial microorganisms.
The chemical safety assessment using EQPM does not suggest any unacceptable risks for the terrestrial compartment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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