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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A valid OECD 211 study performed as a limit test according to GLP is available for a substance in the same subgroup of the category ( Fatty acids, C16-18 and C18-unsatd., Me esters, epoxidized, reaction products with ethylene glycol (CAS 211450 -54 -3). The No Observed Effect (NOEC) concentration was > 10 mg/l.
This substance is part of the Dossier Improvement Pilot Project (DIP) as a member of the category “Epoxidized fatty acid esters (EFAE)”, as agreed upon by the European Chemicals Agency (ECHA) and the European Chemical Industry Council (CEFIC).
To confirm the hypothesis a testing proposal for long-term toxicity to aquatic invertebrates for Fatty acids, C16-18 and C18-unsatd., Me esters, polymers with trimethylopropane (CAS 188831 -96 -1) is submitted.
Key value for chemical safety assessment
Additional information
In a 21-day chronic toxicity study, Daphnia magna were exposed to water accommodated fractions of an analogous substance fatty acids, C16 -18 and C18 -unsatd., epoxidized, Me esters, reaction products with ethylene glycol (CAS 211450 -54 -3) prepared at loading rates of 0 (control), 10 mg/L under semistatic daily renewal conditions in accordance with the OECD 211 guideline. The water pH, temperature and dissolved oxygen were within acceptable guideline specifications. Mortality, reproduction and sublethal effects were observed daily.
The following overall effect concentrations (mg/L) were obtained based on nominal
concentrations (loading rate):
LOEC/LOELR > 10 mg/L
NOEC/NOELR ≥ 10 mg/L
No significant mortality or any other additional significant adverse effects or abnormal behavior were observed in any of the test treatments. The data were not sufficient to calculate ECx values for reproduction or mortality. However based on best professional judgment, a 21-day EC0 ≥ 10 mg/L is estimated.
The study was tested with a similar molecule, which has the same structural body, only the reaction products of the functional groups are different. Both substances show similar structural, physico-chemical, environmental and toxicological properties.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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