Predchádzajúce/výsledok
Predchádzajúce/výsledok
Predchádzajúce/výsledok
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
Further instructions
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
There are currently no ongoing consultations.
| 2-piperazin-1-ylethylamine | 205-411-0 | 140-31-8 |
Chronic toxicity/carcinogenicity Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
14/02/2011 14/02/2011 14/02/2011 |
31/03/2011 31/03/2011 31/03/2011 |
Details | |
| 2-Propanol, 1,1'-[[3-[(3-aminopropyl)amino]propyl]imino]bis-, N-tallow alkyl derivs | 307-276-4 | 97592-79-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
| 2-Propenoic acid, (1-methyl-1,2-ethanediyl) bis[oxy(methyl-2,1-ethanediyl)] ester, reaction products with diethylamine | 601-101-8 | 111497-86-0 | Reproductive toxicity (pre-natal developmental toxicity) | 02/06/2014 | 17/07/2014 | Details | |
| 2-Propenoic acid, 1,1'-[(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)]] ester, reaction products with diethylamine | 601-101-8 | 111497-86-0 | Sub-chronic toxicity (90-day): oral | 18/02/2021 | 05/04/2021 | Details | |
| 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, phosphate | 258-053-2 | 52628-03-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/04/2014 29/04/2014 |
13/06/2014 13/06/2014 |
Details | |
| 2-propenoic acid, butyl ester, reaction products with butadiene and sulfur | 947-895-2 | - |
Bioaccumulation aquatic / sediment Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/01/2024 15/01/2024 15/01/2024 15/01/2024 |
29/02/2024 29/02/2024 29/02/2024 29/02/2024 |
Details | |
| 2-Propyn-1-ol, compd. with methyloxirane | 609-530-2 | 38172-91-7 | Sub-chronic toxicity (90-day): oral | 16/10/2014 | 01/12/2014 | Details | |
| 2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane | 941-793-1 | - | Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-Propyn-1-ol, compd. with methyloxirane (EC 609-530-2, CAS 38172-91-7) | 17/04/2015 | 04/06/2015 | Details | |
| 2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane | 941-793-1 | - | Reproductive toxicity (pre-natal developmental toxicity) | 26/04/2019 | 10/06/2019 | Details | |
| 2-tert-butyl-1,4-dimethoxybenzene | 244-216-5 | 21112-37-8 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
| 2-tert-butylphenol | 201-807-2 | 88-18-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
| 2-{N-[2,6-Diamino-4-oxo-4H-pyrimidin-(5Z)-ylidene]-hydrazino}-5-methyl-benzenesulfonic acid | 700-002-8 | - | Reproductive toxicity (pre-natal developmental toxicity) | 16/07/2012 | 30/08/2012 | Details | |
| 3,3'-iminodi(propylamine) | 200-261-2 | 56-18-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
| 3,3'-oxybis(ethyleneoxy)bis(propylamine) | 224-207-2 | 4246-51-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
| 3,3,4,4,5,5,6,6,6-nonafluorohexene | 243-053-7 | 19430-93-4 | Sub-chronic toxicity (90 day): inhalation | 14/08/2014 | 28/09/2014 | Details | |
| 3,3,5-trimethylcyclohexan-1-one | 212-855-9 | 873-94-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
| 3,3-bis[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-1,5-divinyltrisiloxane | 262-061-1 | 60111-54-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/10/2014 16/10/2014 |
01/12/2014 01/12/2014 |
Details | |
| 3,4,5,6,7,8,9,10,11,12,13,14-dodecahydro-2H-cyclododeca[b]pyran | 251-090-5 | 32539-83-6 | Genetic toxicity in vivo | 14/02/2011 | 31/03/2011 | Details | |
| 3,4-dihydroxy-1-[(Z)-octadec-9-enyl]pyrrolidine-2,5-dione | 700-233-4 | - |
Bioaccumulation aquatic / sediment Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
04/09/2023 04/09/2023 04/09/2023 |
19/10/2023 19/10/2023 19/10/2023 |
Details | |
| 3,4-dihydroxybenzonitrile | 241-367-9 | 17345-61-8 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
| 3,5,5-trimethylhexanoic acid | 221-975-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 |
Details | |
| 3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate | 261-665-2 | 59219-71-5 | Sub-chronic toxicity (90-day): oral | 24/02/2020 | 09/04/2020 | Details | |
| 3,5,5-trimethylhexyl acetate | 261-245-9 | 58430-94-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
| 3,5-bis(2,4-dimethylcyclohex-3-en-1-yl)polyheterocycle | - | - | Genetic toxicity in vivo | 16/03/2015 | 30/04/2015 | Details | |
| 3,5-diamino-4-[[4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-2-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]benzoic acid sodium salt | 480-890-9 | 906532-68-1 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 18/11/2014 | 02/01/2015 | Details | |
| 3,5-dimethyl-1,2-dioxolane-3,5-diol | 237-438-9 | 13784-51-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
| 3,6,9,12-tetraazatetradecamethylenediamine | 223-775-9 | 4067-16-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
28/02/2011 28/02/2011 |
14/04/2011 14/04/2011 |
Details | |
| 3,6,9,12-tetraazatetradecamethylenediamine | 223-775-9 | 4067-16-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7). Reproductive toxicity (pre-natal developmental toxicity) |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
Details | |
| 3,6,9,12-tetraoxotridecanol | 245-883-5 | 23783-42-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1) | 21/10/2021 | 07/12/2021 | Details | |
| 3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione | 401-540-3 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/03/2018 26/03/2018 26/03/2018 |
11/05/2018 11/05/2018 11/05/2018 |
Details | |
| 3,6-bis(4-tert-butylphenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione | 416-250-2 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/09/2012 | 12/11/2012 | Details | |
| 3,6-bis-biphenyl-4-yl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione | 413-920-6 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/09/2012 | 12/11/2012 | Details | |
| 3,7-dimethyloct-6-enenitrile | 257-288-8 | 51566-62-2 | Reproductive toxicity (pre-natal developmental toxicity) | 03/03/2014 | 17/04/2014 | Details | |
| 3,7-dimethyloctan-1-ol | 203-374-5 | 106-21-8 | Reproductive toxicity (pre-natal developmental toxicity) | 31/01/2014 | 17/03/2014 | Details | |
| 3,9-dicyclohex-3-enyl-2,4,8,10-tetraoxaspiro[5.5]undecane | 229-542-8 | 6600-31-3 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
| 3,9-dimethyl-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-dioxide | 221-088-9 | 3001-98-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
| 3-((5-(3-(Dodecanoyloxy)-2,2-dimethylpropylideneamino)-1,3,3-trimethylcyclohexyl)methylimino)-2,2-dimethylpropyl dodecanoate | 700-071-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2012 16/05/2012 |
02/07/2012 02/07/2012 |
Details | |
| 3-((C12-18)-acylamino)-N-(2-((2-hydroxyethyl)amino)-2-oxoethyl)-N,N-dimethyl-1-propanaminium chloride | 427-370-1 | 164288-56-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/04/2023 | 22/05/2023 | Details | |
| 3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine | 939-485-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| 3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine acetate (1:1) | 939-448-5 | - |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)- Sub-chronic toxicity (90-day): oral
|| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)- |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| 3-(benzothiazol-2-yl)-7-(diethylamino)-2-oxo-2H-1-benzopyran-4-carbonitrile | 274-668-9 | 70546-25-7 | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
| 3-(diethylamino)-7-oxo-7H-[1]benzopyrano[3',2':3,4]pyrido[1,2-a]benzimidazole-6-carbonitrile | 257-884-8 | 52372-36-8 | Genetic toxicity in vivo | 26/10/2022 | 12/12/2022 | Details | |
| 3-(Diisobutoxy-thiophosphorylsulfanyl)-2-methyl-propionic acid | 434-070-2 | - | Sub-chronic toxicity (90-day): oral | 18/02/2013 | 04/04/2013 | Details | |
| 3-(dimethylamino)propylurea | 401-950-2 | 31506-43-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 |
Details | |
| 3-(isodecyloxy)propylammonium acetate | 249-166-8 | 28701-67-9 | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
| 3-(triethoxysilyl)propanethiol | 238-883-1 | 14814-09-6 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/10/2014 16/10/2014 16/10/2014 |
01/12/2014 01/12/2014 01/12/2014 |
Details | |
| 3-(trimethoxysilyl)propiononitrile | 219-764-3 | 2526-62-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/03/2014 21/03/2014 |
05/05/2014 05/05/2014 |
Details | |
| 3-(Trimethoxysilyl)propyl (2E,4E)-hexa-2,4-dienoate | 642-902-2 | 163802-53-7 | Genetic toxicity in vivo | 10/03/2017 | 25/04/2017 | Details | |
| 3-(trimethoxysilyl)propyl isocyanate | 239-415-9 | 15396-00-6 |
Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: it is proposed to use the information from an ongoing study with 3-(trimethoxysilyl)propylamine (EC 237-511-5) |
30/09/2021 30/09/2021 |
15/11/2021 15/11/2021 |
Details | |
| 3-(trimethoxysilyl)propylamine | 237-511-5 | 13822-56-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/04/2019 26/04/2019 |
10/06/2019 10/06/2019 |
Details | |