Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Zobrazuje sa 1 001 - 1 200 z 1 996 výsledkov.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
ASPHALT	232-490-9	8052-42-4	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	31/05/2016 31/05/2016	15/07/2016 15/07/2016	Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, esters with acrylic acid	500-130-2	55818-57-0	Reproductive toxicity (pre-natal developmental toxicity)	31/05/2016	15/07/2016	Details
ALCOHOLS, C11-14-ISO-, C13-RICH	271-235-6	68526-86-3	Sub-chronic toxicity (90-day): oral	31/05/2016	15/07/2016	Details
ALCOHOLS, C7-9-ISO-, C8-RICH	271-231-4	68526-83-0	Sub-chronic toxicity (90-day): oral	31/05/2016	15/07/2016	Details
Propylidynetrimethyl trimethacrylate	221-950-4	3290-92-4	Reproductive toxicity (pre-natal developmental toxicity)	31/05/2016	15/07/2016	Details
Reaction mass of C18 (unsatd.) fatty acid amides/esters of diethanolamine, C16-18 (even-numbered) fatty amine (..)	943-172-0	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (extended one-generation reproductive toxicity study)	17/05/2016 17/05/2016 17/05/2016	01/07/2016 01/07/2016 01/07/2016	Details
Melamine	203-615-4	108-78-1	Reproductive toxicity (extended one-generation reproductive toxicity study)	17/05/2016	01/07/2016	Details
Methylene-bis-4,1-(N-phenylene-N'-butylurea)	416-600-4	-	Bioaccumulation aquatic / sediment	17/05/2016	01/07/2016	Details
1,1,3,3-tetramethyldisiloxane	221-906-4	3277-26-7	Sub-chronic toxicity (90 day): inhalation Reproductive toxicity (pre-natal developmental toxicity)	29/04/2016 29/04/2016	13/06/2016 13/06/2016	Details
2,2'-[OXYBIS(METHYLENE)]BIS[2-ETHYLPROPANE-1,3-DIOL]	245-509-0	23235-61-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/04/2016 29/04/2016	13/06/2016 13/06/2016	Details
COBALT DICHLORIDE	231-589-4	7646-79-9	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	29/04/2016 29/04/2016	13/06/2016 13/06/2016	Details
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate	250-418-4	30989-05-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	29/04/2016 29/04/2016	13/06/2016 13/06/2016	Details
N,N''-propane-1,3-diylbis[N'-octadecylurea	252-667-4	35674-65-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	29/03/2016	13/05/2016	Details
1-isopropyl-2,2-dimethyltrimethylene diisobutyrate	229-934-9	6846-50-0	Reproductive toxicity (pre-natal developmental toxicity)	14/03/2016	28/04/2016	Details
2,2'-(C16-18 (evennumbered, C18 unsaturated) alkyl imino) diethanol	620-540-6	1218787-32-6	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2,2'-(Octadec-9-enylimino) bisethanol, CAS No 25307-17-9	14/03/2016	28/04/2016	Details
Shale oils	269-646-0	68308-34-9	Reproductive toxicity (extended one-generation reproductive toxicity study) “\|\| Note: testing proposed with Shale oils, heavy fractions (Registration No 01-2119756217-35-0000)” Sub-chronic toxicity (90-day): oral “\|\| Note: testing proposed with Shale oils, heavy fractions (Registration No 01-2119756217-35-0000)”	14/03/2016	28/04/2016	Details
Shale oils, light	923-592-0	-	Reproductive toxicity (extended one-generation reproductive toxicity study) “\|\| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)\|\|” Sub-chronic toxicity (90-day): oral “\|\| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)\|\|”	14/03/2016	28/04/2016	Details
2,2-dimethylpropane-1,3-diyl dibenzoate	224-081-9	4196-89-8	Reproductive toxicity (pre-natal developmental toxicity)	29/02/2016	14/04/2016	Details
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide	271-794-6	68608-66-2	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Reaction products of 1H-Imidazole- 1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0	29/02/2016	14/04/2016	Details
N-butylbenzenesulphonamide	222-823-6	3622-84-2	Reproductive toxicity (pre-natal developmental toxicity)	29/02/2016	14/04/2016	Details
2,2'-dimethyl-2,2'-azodipropiononitrile	201-132-3	78-67-1	Reproductive toxicity (pre-natal developmental toxicity)	03/02/2016	21/03/2016	Details
2-(2-Ethoxyethoxy)-2-methylpropanee	257-196-8	51422-54-9	Sub-chronic toxicity (90 day): inhalation Reproductive toxicity (pre-natal developmental toxicity)	03/02/2016	21/03/2016	Details
Esterification products of 4,4'-isopropylidenediphenol, ethoxylated and prop-2-enoic acid.	613-584-2	64401-02-1	Genetic toxicity in vivo	03/02/2016	21/03/2016	Details
O,O,O-triphenyl phosphorothioate	209-909-9	597-82-0	Reproductive toxicity (extended one-generation reproductive toxicity study) “\|\| Note: Testing proposal is based on concern identified by the registrant.”	03/02/2016	21/03/2016	Details
Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane	608-489-8	-	Genetic toxicity in vivo	03/02/2016	21/03/2016	Details
triethoxy(3-isocyanatopropyl)silane	246-467-6	24801-88-5	Genetic toxicity in vivo Note: testing proposed with 3-(Trimethoxysilyl)propyl isocyanate (EC 239-415-9)	03/02/2016	21/03/2016	Details
1,4-Cyclohexanedimethanol, reaction products with epichlorohydrin	600-447-7	1035218-79-1	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Link to registration dossier not given as the dossier not yet disseminated Sub-chronic toxicity (90 day): inhalation \|\| Note: Link to registration dossier not given as the dossier not yet disseminated	23/12/2015 23/12/2015	03/02/2016 03/02/2016	Details
Poly(oxy-1,2-ethanediyl), .alpha.-[3-[(carboxymethyl)methylamino]-2-hydroxypropyl]-.omega.-(4-nonylphenoxy)-, monosodium sal	616-248-3	75627-31-5	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity	23/12/2015 23/12/2015	03/02/2016 03/02/2016	Details
Reaction products of polyaminoalkane and substituted octadecanoic acid	434-430-9	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	16/12/2016 16/12/2016	30/01/2016 30/01/2017	Details
Amines, tallow alkyl, dodecylbenzenesulfonates	268-766-0	68139-94-6	Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: Testing proposal is based on concern identified by the registrant Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015 30/11/2015 30/11/2015	14/01/2016 14/01/2016 14/01/2016	Details
Formaldehyde, oligomeric reaction products with phenol and m-phenylenebis(methylamine)	500-137-0	57214-10-5	Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015 30/11/2015 30/11/2015	14/01/2016 14/01/2016 14/01/2016	Details
2,4-Pentanedione, peroxide	253-384-9	37187-22-7	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015 30/11/2015	14/01/2016 14/01/2016	Details
Distilled tall oil, magnesium salts	939-629-9	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015 30/11/2015	14/01/2016 14/01/2016	Details
Fatty acids, C18-unsatd., dimers, reaction products with polyethylenepolyamines	614-452-7	68410-23-1	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (CAS 68082-29-1) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (CAS 68082-29-1)	30/11/2015 30/11/2015	14/01/2016 14/01/2016	Details
orthoboric acid, compound with 2,2'-iminodiethanol	267-886-0	67952-33-4	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with MEA Polyborate Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with MEA Polyborate	30/11/2015 30/11/2015	14/01/2016 14/01/2016	Details
Reaction mass of (2S-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2R,4R) and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2S,4S) and (2R-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran	939-429-1	16409-43-1	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015 30/11/2015	14/01/2016 14/01/2016	Details
(octadecanoato-O)oxoaluminium	236-521-7	13419-15-3	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Aluminum, benzoate C16-18 fatty acid complexes (CAS 94166-87-7)	30/11/2015	14/01/2016	Details
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	248-227-6	27107-89-7	Genetic toxicity in vivo	30/11/2015	14/01/2016	Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	246-678-3	25155-25-3	Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015	14/01/2016	Details
D-glucopyranose, oligomeric, C10-16 glycosides (even numbered), carboxymethyl ethers, sodium salts	609-542-8	383178-66-3	Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015	14/01/2016	Details
Fats and Glyceridic oils, vegetable, winterized, reaction products with ammonia-ethanolamine reaction products	800-253-4	-	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Link to registration dossier not given as the dossier not yet disseminated.	30/11/2015	14/01/2016	Details
Hydrochloric acid, reaction products with aniline and nitrobenzene, sulfonated, sodium salts	291-454-0	90411-76-0	Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015	14/01/2016	Details
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide	806-543-7	215917-77-4	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	30/11/2015	14/01/2016	Details
Reaction products of tryglycerides, C8-C18 (even numbered) and C18-unsaturated, glycerine and ethylene oxide	939-459-5	-	Sub-chronic toxicity (90-day): oral	30/11/2015	14/01/2016	Details
8,9,10-trinorborn-2-ene	207-866-0	498-66-8	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (extended one-generation reproductive toxicity study)	01/11/2015 01/11/2015	16/12/2015 16/12/2015	Details
Amines, polyethylenepoly-, tetraethylenepentamine fraction	292-587-7	90640-66-7	Reproductive toxicity (extended one-generation reproductive toxicity study)	01/11/2015	16/12/2015	Details
N-vinylformamide	236-102-9	13162-05-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	01/11/2015	16/12/2015	Details
N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide)	204-613-6	123-26-2	Sub-chronic toxicity (90 day): oral Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with: “Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine”, CAS 100545-48-0 Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	30/09/2015 30/09/2015 30/09/2015	16/11/2015 16/11/2015 16/11/2015	Details
Poly[oxy(methyl-1,2-ethanediyl)], a-hydro-omega-hydroxy-, ether with 2,6 bis{[(2-hydroxyethyl)amino]methyl}-4-nonylphenol	614-668-1	68610-97-9	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/09/2015 30/09/2015	16/11/2015 16/11/2015	Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol]	245-509-0	23235-61-2	Sub-chronic toxicity (90-day): oral	30/09/2015	16/11/2015	Details
dihydro-3-(tripropenyl)furan-2,5-dione	295-556-6	92077-08-2	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2015	16/11/2015	Details
sodium toluene-4-sulphonate	211-522-5	657-84-1	Reproductive toxicity (extended one-generation reproductive toxicity study)	30/09/2015	16/11/2015	Details
tetraethylammonium hydroxide	201-073-3	77-98-5	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with N,N,N-trimethylmethanaminium chloride (EC 200-880-8; CAS 75-57-0)	30/09/2015	16/11/2015	Details
Esterification products of 4,4'-Isopropylidenediphenol, ethoxylated and prop-2-enoic acid and 3,5,5-trimethylhexanoic acide	919-846-5	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with an analogous substance	31/08/2015 31/08/2015	15/10/2015 15/10/2015	Details
Tri(isopropyl)silyl acrylate	457-670-6	157859-20-6	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	31/08/2015 31/08/2015	15/10/2015 15/10/2015	Details
Tri(isopropyl)silyl acrylate	457-670-6	157859-20-6	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	31/08/2015 31/08/2015	15/10/2015 15/10/2015	Details
3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one	241-753-7	17772-51-9	Reproductive toxicity (pre-natal developmental toxicity)	31/08/2015	15/10/2015	Details
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide]	258-981-8	54112-23-1	Long-term toxicity to fish Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.	31/08/2015	15/10/2015	Details
trimethoxyoctylsilane	221-338-7	3069-40-7	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (CAS 35435-21-3)	07/08/2015	22/09/2015	Details
Urea, N-octyl-N'-[4-[[4-[[(octylamino)carbonyl]amino]phenyl]methyl]phenyl]-Urea, N-[4-[[4[(octadecylamino)carbonyl]amino]phenyl]methyl]phenyl]-N’-octyl	445-760-8	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	31/07/2015 31/07/2015	14/09/2015 14/09/2015	Details
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol	204-137-9	116-37-0	Reproductive toxicity (pre-natal developmental toxicity)	31/07/2015	14/09/2015	Details
Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane	608-489-8	30499-70-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015 25/06/2015 25/06/2015	10/08/2015 10/08/2015 10/08/2015	Details
1,1,1,3,5,5,5-heptamethyltrisiloxane	217-496-1	1873-88-7	Sub-chronic toxicity (90 day): inhalation Note: testing proposed with 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7. Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with Octamethyltrisiloxane, CAS 107-51-7 and 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
1,1,3,3-tetramethyl-1,3-divinyldisiloxane	220-099-6	2627-95-4	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
4-trans-Propyl-4-trans-vinyl-[1,1-bicylohexyl]	601-409-2	116020-44-1	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
dichloro(diphenyl)silane	201-251-0	80-10-4	Sub-chronic toxicity (90-day): oral Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
dimethoxydiphenylsilane	229-929-1	6843-66-9	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
N-[3-(dimethoxymethylsilyl)-2-methylpropyl]ethylenediamine	245-642-4	23410-40-4	Sub-chronic toxicity (90-day): oral Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6) Reproductive toxicity (pre-natal developmental toxicity) Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
N-[3-(dimethoxymethylsilyl)propyl]ethylenediamine	221-336-6	3069-29-2	Sub-chronic toxicity (90-day): oral Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3. Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3.	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
Reaction mass of 6-Amino-5-(4-substituted-sulfophenylazo)-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt and 6-Amino-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-5-[sulfo- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt	445-040-3	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
Reaction mass of [[(2-hydroxyethyl)imino]dimethylene]bisphosphonic acid, sodium salt and 4-(Phosphonomethyl)-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane, sodium salt	939-513-8	-	Sub-chronic toxicity (90-day): oral Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
trichloro(hexadecyl)silane	227-575-2	5894-60-0	Sub-chronic toxicity (90-day): oral Note: testing proposed with hexadecyl(trimethoxy)silane (EC 240-464-3, CAS 16415-12-6) Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with hexadecyl(trimethoxy)silane (EC 240-464-3, CAS 16415-12-6)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
Ureidopropyltrialkoxysilane	449-160-7	116912-64-2	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
1,1'-dithiobis[hexahydro-2H-azepin-2-one]	245-910-0	23847-08-7	Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015	10/08/2015	Details
A mixture of: cis-tetrahydro-2-isobutyl-4-methylpyran-4-ol; trans-tetrahydro-2-isobutyl-4-methylpyran-4-ol	405-040-6	63500-71-0	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/06/2015	10/08/2015	Details
Aluminum, benzoate C16-18-fatty acids complexes	303-385-6	94166-87-7	Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015	10/08/2015	Details
butan-2-one O,O',O''-(vinylsilylidyne)trioxime	218-747-8	2224-33-1	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with Butan-2-one O,O',O''-(methylsilylidyne)trioxime (CAS 22984-54-9).	25/06/2015	10/08/2015	Details
dodecamethylpentasiloxane	205-492-2	141-63-9	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with Decamethyltetrasiloxane (EC 205-491-7).	25/06/2015	10/08/2015	Details
octyltrichlorosilane	226-112-1	5283-66-9	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3)	25/06/2015	10/08/2015	Details
potassium 4-isopropylbenzenesulphonate	629-764-9	164524-02-1	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/06/2015	10/08/2015	Details
Reaction mass of sodium hydrogen N-(1-oxooctadecyl)-L-glutamate and stearic acid	939-201-1	-	Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015	10/08/2015	Details
Sodium N-lauroylsarcosinate	205-281-5	137-16-6	Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015	10/08/2015	Details
triethoxy(phenyl)silane	212-305-8	780-69-8	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with trimethoxy(phenyl)silane (EC 221-066-9, CAS 2996-92-1)	25/06/2015	10/08/2015	Details
trimethoxy(2,4,4-trimethylpentyl)silane	251-995-5	34396-03-7	Sub-chronic toxicity (90-day): oral Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) "	25/06/2015	10/08/2015	Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one	403-830-5	89331-94-2	Bioaccumulation aquatic / sediment	12/06/2015	27/07/2015	Details
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid	252-156-6	34690-00-1	Sub-chronic toxicity (90-day): oral \|\| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposal is based on concern identified by the registrant.	20/05/2015 20/05/2015	06/07/2015 06/07/2015	Details
Phosphoric acid, mixed esters with Bu alc. and ethylene glycol	284-716-0	84962-20-9	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphoric acid, butyl ester; CAS No. 12788-93-1 Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphoric acid, butyl ester; CAS No. 12788-93-1	20/05/2015 20/05/2015	06/07/2015 06/07/2015	Details
Reaction mass of methyl dihydrogen phosphate and orthophosphoric acid and dimethyl hydrogen phosphate	908-996-7	-	Sub-chronic toxicity (90-day): oral \|\| Note: Testing is proposed with Phosphoric acid, butyl ester (CAS 12788-93-1). Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing is proposed with Phosphoric acid, butyl ester (CAS 12788-93-1).	20/05/2015 20/05/2015	06/07/2015 06/07/2015	Details
diammonium hexanitratocerate	240-827-6	16774-21-3	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Cerium (III) nitrate (CAS 10294-41-4)	20/05/2015	06/07/2015	Details
sodium p-cumenesulphonate	239-854-6	15763-76-5	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Sodium xylene sulphonate	24/04/2015	12/06/2015	Details
2-methylbut-3-yn-2-ol	204-070-5	115-19-5	Sub-chronic toxicity (90-day): oral	20/04/2015	08/06/2015	Details
1,1'-(p-tolylimino)dipropan-2-ol	254-075-1	38668-48-3	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015 14/03/2016	04/06/2015 28/04/2016	Details
Phosphoric acid, octadecyl ester	254-466-7	39471-52-8	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015 17/04/2015 17/04/2015 17/04/2015	04/06/2015 04/06/2015 04/06/2015 04/06/2015	Details
N-octadecylstearamide	236-276-6	13276-08-9	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015 17/04/2015 17/04/2015	04/06/2015 04/06/2015 04/06/2015	Details
Reaction mass of [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid and Phosphonic acid, P-[(tetrahydro-2-hydroxy-2-oxido-4H-1,4,2-oxazaphosphorin-4-yl)methyl]-	911-811-2	-	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015 17/04/2015 17/04/2015	04/06/2015 04/06/2015 04/06/2015	Details
2,2-dimethyl-1,3-dioxolan-4-ylmethanol	202-888-7	100-79-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015 17/04/2015	04/06/2015 04/06/2015	Details
[3-(triethoxysilyl)propyl]urea	245-876-7	23779-32-0	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015 17/04/2015	04/06/2015 04/06/2015	Details
barium titanium trioxide	234-975-0	12047-27-7	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015 17/04/2015	04/06/2015 04/06/2015	Details
Phosphoric acid, butyl ester	235-826-2	12788-93-1	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015 17/04/2015	04/06/2015 04/06/2015	Details
(3-chloropropyl)diethoxymethylsilane	236-828-6	13501-76-3	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposed with (3-chloropropyl)triethoxysilane (CAS 5089-70-3)	17/04/2015	04/06/2015	Details
(3-chloropropyl)dimethoxymethylsilane	242-056-0	18171-19-2	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6)”	17/04/2015	04/06/2015	Details
(3E)-2-chloro-3-(hydroxymethylene)cyclohexene-1-carbaldehyde	801-656-8	1416808-92-8	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	17/04/2015	04/06/2015	Details
2,2-dimethylpropan-1-ol, tribromo derivative	253-057-0	36483-57-5	Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015	04/06/2015	Details
2-ethyl-2-[[(1-oxononyl)oxy]methyl]propane-1,3-diyl dinonan-1-oate	204-793-6	126-57-8	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	17/04/2015	04/06/2015	Details
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane	941-793-1	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 2-Propyn-1-ol, compd. with methyloxirane (EC 609-530-2, CAS 38172-91-7)	17/04/2015	04/06/2015	Details
cerium trinitrate	233-297-2	10108-73-3	Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015	04/06/2015	Details
Reaction mass of potassium ethyl octylphosphonate and diethyl octylphosphonate	939-595-5	-	Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015	04/06/2015	Details
Triethoxyoctylsilane	220-941-2	2943-75-1	Long-term toxicity to fish \|\| Note: testing proposed with Triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1)	17/04/2015	04/06/2015	Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-C13 odd-numbered alkyl) derivs. and sodium hydroxide and chloroacetic acid	938-645-3	-	Long-term toxicity to fish Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11 alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 271-794-6) Sub-chronic toxicity (90-day): oral Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0) Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)	16/03/2015 16/03/2015 16/03/2015	30/04/2015 30/04/2015 30/04/2015	Details
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and tetraethylenepentamine	500-289-8	103758-98-1	Sub-chronic toxicity (90-day): oral \|\|Note: testing proposed with [Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine] (CAS 68082-29-1) Reproductive toxicity (pre-natal developmental toxicity) \|\|Note: testing proposed with [Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine] (CAS 68082-29-1)	16/03/2015 16/03/2015	30/04/2015 30/04/2015	Details
tripotassium propylsilanetriolate	299-135-8	93857-00-2	Sub-chronic toxicity (90 day): inhalation Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7) Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7)	16/03/2015 16/03/2015	30/04/2015 30/04/2015	Details
2-benzofuran-1,3-dione; 2-(2-hydroxyethoxy)ethanol	608-744-3	32472-85-8	Reproductive toxicity (pre-natal developmental toxicity)	16/03/2015	30/04/2015	Details
3,5-bis(2,4-dimethylcyclohex-3-en-1-yl)polyheterocycle	-	-	Genetic toxicity in vivo	16/03/2015	30/04/2015	Details
dichlorocyclohexylmethylsilane	226-956-0	5578-42-7	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with [dicyclopentyldimethoxysilane] (CAS 126990-35-0)	16/03/2015	30/04/2015	Details
dipotassium heptafluorotantalate	240-986-1	16924-00-8	Genetic toxicity in vivo	16/03/2015	30/04/2015	Details
Fatty acids, C16-18, reaction products with diethanolamine	293-014-3	91032-08-5	Reproductive toxicity (pre-natal developmental toxicity)	16/03/2015	30/04/2015	Details
methylsilanetriyl triacetate	224-221-9	4253-34-3	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with [Trimethoxy(methyl)silane] (EC 214-685-0)	16/03/2015	30/04/2015	Details
tellurium dioxide	231-193-1	7446-07-3	Sub-chronic toxicity (90-day): oral	16/03/2015	30/04/2015	Details
tert-butyl α,α-dimethylbenzyl peroxide	222-389-8	3457-61-2	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	16/03/2015	30/04/2015	Details
4-methylmorpholine 4-oxide, monohydrate	231-391-8	7529-22-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity)	16/02/2015 16/02/2015 16/02/2015	02/04/2015 02/04/2015 02/04/2015	Details
9-Octadecenoic acid (Z)-, sulfonated, potassium salts	271-843-1	68609-93-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity)	16/02/2015 16/02/2015 16/02/2015	02/04/2015 02/04/2015 02/04/2015	Details
Benzene-1,2,4-tricarboxylic acid 1,2-anhydride, oligomeric reaction products with ethane-1,2-diol and glycerol	500-199-9	68183-39-1	Sub-chronic toxicity (90-day): oral Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity)	16/02/2015 16/02/2015 16/02/2015	02/04/2015 02/04/2015 02/04/2015	Details
reaction mass of bis(2,3-epoxypropyl) terephthalate and tris(oxiranylmethyl) benzene-1,2,4-tricarboxylate	940-592-6	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: Testing proposal is based on concern identified by the registrant Reproductive toxicity (pre-natal developmental toxicity)	16/02/2015 16/02/2015 16/02/2015	02/04/2015 02/04/2015 02/04/2015	Details
(1,4-diazabicyclo[2.2.2]octane-2-yl)methanol	692-731-2	76950-43-1	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	16/02/2015 16/02/2015	02/04/2015 02/04/2015	Details
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl	218-760-9	2226-96-2	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	16/02/2015 16/02/2015	02/04/2015 02/04/2015	Details
Phosphorous acid, tri-C12-14-alkyl esters	297-701-9	93686-48-7	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity)	16/02/2015 16/02/2015	02/04/2015 02/04/2015	Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane	219-784-2	2530-83-8	Genetic toxicity in vivo	16/02/2015	02/04/2015	Details
bis(piperidinothiocarbonyl) hexasulphide	213-537-2	971-15-3	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	16/02/2015	02/04/2015	Details
Polysulfides, di-tert-dodecyl	270-335-7	68425-15-0	Bioaccumulation aquatic / sediment	16/02/2015	02/04/2015	Details
Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, reaction products with polyethylenepolyamines and tall-oil fatty acids, humates hydrochlorides	272-745-1	68910-55-4	Long-term toxicity to fish Sub-chronic toxicity (90 day): inhalation Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity)	23/01/2015 23/01/2015 23/01/2015 23/01/2015	09/03/2015 09/03/2015 09/03/2015 09/03/2015	Details
D-glucopyranose, oligomers, xylityl glycosides and 1,4 anhydro D-xylitol and D-xylitol	446-990-1	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	23/01/2015 23/01/2015	09/03/2015 09/03/2015	Details
tetrahydro-2-methylfuran	202-507-4	96-47-9	Sub-chronic toxicity (90 day): inhalation Reproductive toxicity (pre-natal developmental toxicity)	23/01/2015 23/01/2015	09/03/2015 09/03/2015	Details
Aromatic hydrocarbons, C10-13, reaction products with branched nonene, sulfonated, sodium salts	800-660-7	1258274-08-6	Reproductive toxicity (pre-natal developmental toxicity)	23/01/2015	09/03/2015	Details
Copper (2+), bis [N-{amino (imino-KN) methyl} urea-KO]-, nitrate (1:2)	800-038-5	1071838-81-7	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	23/01/2015	09/03/2015	Details
tin monoxide	244-499-5	21651-19-4	Sub-chronic toxicity (90 day): inhalation	23/01/2015	09/03/2015	Details
N,N'-bis(2,2,6,6-tetramethyl-4-piperidyl)isophthalamide	419-710-0	-	Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	12/12/2014 12/12/2014 12/12/2014	26/01/2015 26/01/2015 26/01/2015	Details
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide]	258-981-8	54112-23-1	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	12/12/2014 12/12/2014	26/01/2015 26/01/2015	Details
N-(dimethylvinylsilyl)-1,1-dimethyl-1-vinylsilylamine	231-701-1	7691-02-3	Sub-chronic toxicity (90 day): inhalation “\|\| Note: Testing proposed with hexamethyldisilazane (CAS 999-97-3)” Reproductive toxicity (pre-natal developmental toxicity) “\|\| Note: Testing proposed with hexamethyldisilazane (CAS 999-97-3)”	12/12/2014 12/12/2014	26/01/2015 26/01/2015	Details
Reaction mass of ethoxylated (≥ 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate	939-702-5	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Ethoxylated bisphenol A diacrylate Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Ethoxylated bisphenol A diacrylate	12/12/2014 12/12/2014	26/01/2015 26/01/2015	Details
1,1,1,3,5,5,5-heptamethyl-3-[(trimethylsilyl)oxy]trisiloxane	241-867-7	17928-28-8	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with decamethyltetrasiloxane (EC no. 205-491-7, CAS no. 141-62-8)	12/12/2014	26/01/2015	Details
1,1,4,4-tetramethylbutane-1,4-diyl bis(2-ethylperoxyhexanoate)	235-935-5	13052-09-0	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	12/12/2014	26/01/2015	Details
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers, reaction products with 2-butanone oxime	500-287-7	103170-26-9	Sub-chronic toxicity (90 day): inhalation	12/12/2014	26/01/2015	Details
chlorodimethylvinylsilane	217-007-1	1719-58-0	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Trimethylsilanol (CAS 1066-40-6)	12/12/2014	26/01/2015	Details
Hexamethylene diisocyanate, oligomerisation product, blocked with 3,5-dimethyl-1H-pyrazole	605-318-9	163206-31-3	Sub-chronic toxicity (90 day): inhalation	12/12/2014	26/01/2015	Details
Reaction mass of Amines, coco alkyl and β-Alanine, N-(2-carboxyethyl)-, N-coco alkyl derivs. and β-Alanine, N-coco alkyl derivs.	915-790-0	-	Sub-chronic toxicity (90-day): oral	12/12/2014	26/01/2015	Details
Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane	618-939-5	933999-84-9	Sub-chronic toxicity (90 day): dermal Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity)	18/11/2014 18/11/2014 18/11/2014	02/01/2015 02/01/2015 02/01/2015	Details
Reaction mass of 2,2'-[(4-methylphenyl)imino]bisethanol and Ethanol 2-[[2-(2-hydroxyethoxy)ethyl](4-methylphenyl)amino]-	911-490-9	-	Reproductive toxicity (pre-natal developmental toxicity) Genetic toxicity in vivo	18/11/2014 18/11/2014	02/01/2015 02/01/2015	Details
3,5-diamino-4-[[4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-2-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]benzoic acid sodium salt	480-890-9	906532-68-1	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	18/11/2014	02/01/2015	Details
2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo[d,g][1,3,2]dioxaphosphocin 6-oxide, sodium salt	286-344-4	85209-91-2	Long-term toxicity to fish Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity)	16/10/2014 16/10/2014 16/10/2014	01/12/2014 01/12/2014 01/12/2014	Details
3-(triethoxysilyl)propanethiol	238-883-1	14814-09-6	Reproductive toxicity (pre-natal developmental toxicity) Genetic toxicity in vivo Sub-chronic toxicity (90-day): oral	16/10/2014 16/10/2014 16/10/2014	01/12/2014 01/12/2014 01/12/2014	Details
triethoxy(3-thiocyanatopropyl)silane	252-161-3	34708-08-2	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/10/2014 16/10/2014 16/10/2014	01/12/2014 01/12/2014 01/12/2014	Details
2-Oxepanone, polymer with 1,6-hexanediol	609-271-5	36609-29-7	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol	16/10/2014 16/10/2014	01/12/2014 01/12/2014	Details
3,3-bis[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-1,5-divinyltrisiloxane	262-061-1	60111-54-8	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/10/2014 16/10/2014	01/12/2014 01/12/2014	Details
Fatty acids, C18-unsatd., dimers, polymers with oleic acid and triethylenetetramine	614-339-2	68154-62-1	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (EC 500-191-5, CAS 68082-29-1) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (EC 500-191-5, CAS 68082-29-1)	16/10/2014 16/10/2014	01/12/2014 01/12/2014	Details
hexadecyltrimethoxysilane	240-464-3	16415-12-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/10/2014 16/10/2014	01/12/2014 01/12/2014	Details
(chloromethyl)triethoxysilane	239-311-3	15267-95-5	Genetic toxicity in vivo	16/10/2014	01/12/2014	Details
2-Propyn-1-ol, compd. with methyloxirane	609-530-2	38172-91-7	Sub-chronic toxicity (90-day): oral	16/10/2014	01/12/2014	Details
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline)	407-560-9	107934-68-9	Bioaccumulation aquatic / sediment \|\| Note: Testing proposal is based on concern identified by the registrant.	16/10/2014	01/12/2014	Details
decamethyltetrasiloxane	205-491-7	141-62-8	Reproductive toxicity (pre-natal developmental toxicity)	16/10/2014	01/12/2014	Details
dichloro(3-chloropropyl)methylsilane	232-136-3	7787-93-1	Reproductive toxicity (pre-natal developmental toxicity)\|\| Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6, CAS 5089-70-3)	16/10/2014	01/12/2014	Details
dimethoxydimethylsilane	214-189-4	1112-39-6	Sub-chronic toxicity (90 day): inhalation	16/10/2014	01/12/2014	Details
dimethoxymethylsilane	240-914-9	16881-77-9	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with trimethoxy(methyl)silane.	16/10/2014	01/12/2014	Details
Hexafluoropropene, oxidized, oligomers, reduced, fluorinated	500-537-5	161075-00-9	Bioaccumulation aquatic / sediment	16/10/2014	01/12/2014	Details
hexahydrophthalic acid diglycidylester	696-026-0	1395383-69-3	Sub-chronic toxicity (90-day): oral	16/10/2014	01/12/2014	Details
Octadecylamine, reaction products with 4,4'-methylenediphenyl diisocyanate	928-226-3	-	Sub-chronic toxicity (90-day): oral	16/10/2014	01/12/2014	Details
reaction mass of: triphenylthiophosphate and tertiary butylated phenyl derivatives	421-820-9	192268-65-8	Reproductive toxicity (pre-natal developmental toxicity)	16/10/2014	01/12/2014	Details
triethoxy(methyl)silane	217-983-9	2031-67-6	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with trimethoxy(methyl)silane.	16/10/2014	01/12/2014	Details
undec-10-enoic acid	203-965-8	112-38-9	Long-term toxicity to fish	16/10/2014	01/12/2014	Details
Esterification products of 4,4'-isopropylidenediphenol, ethoxylated and prop-2-enoic acid.	613-584-2	64401-02-1	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	18/09/2014 18/11/2014	03/11/2014 02/01/2015	Details
1,3-diphenylpropane-1,3-dione	204-398-9	120-46-7	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) Genetic toxicity in vivo	18/09/2014 18/09/2014 18/09/2014	03/11/2014 03/11/2014 03/11/2014	Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts	939-457-4	-	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	18/09/2014 18/09/2014 18/09/2014	03/11/2014 03/11/2014 03/11/2014	Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts	939-455-3	-	Long-term toxicity to fish Sub-chronic toxicity (90 day): oral Reproductive toxicity (pre-natal developmental toxicity)	18/09/2014 18/09/2014 18/09/2014	03/11/2014 03/11/2014 03/11/2014	Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene]	244-617-5	21850-44-2	Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity)	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
1,4-diisopropylbenzene	202-826-9	100-18-5	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with CAS no. 99-62-7 Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with CAS no. 99-62-7	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
2-amino-2-ethylpropanediol	204-101-2	115-70-8	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 2-amino-1,3-propanediol Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 2-amino-1,3-propanediol	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylated	614-503-3	68441-62-3	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposed on rabbit. Reproductive toxicity (two-generation reproductive toxicity)	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with 2-methylimidazole	500-181-0	68002-42-6	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
4-methylthiosemicarbazide	229-563-2	6610-29-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
bismuth citrate	212-390-1	813-93-4	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4)	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
fatty acids, C16 and C18 unsatd., polymers with bisphenol A, Bu glycidyl ether, epichlorohydrin and triethylenetetramine	600-687-2	105839-18-7	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
hex-3-yne-2,5-diol	221-209-5	3031-66-1	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
N-[3-(dimethylamino)propyl] C 12-C18 alkylamide	932-121-8	1147459-12-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
N-[3-(trimethoxysilyl)propyl]butylamine // Note: testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC No. 217-164-6)	250-437-8	31024-56-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
sodium O,O-diethyl dithiophosphate \|\| Note: testing proposed with sodium O,O-diisobutyl dithiophosphate (EC 258-508-5)	222-079-2	3338-24-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate)	202-319-2	94-28-0	Reproductive toxicity (two-generation reproductive toxicity)	18/09/2014	03/11/2014	Details
3-methoxy-3-methylbutan-1-ol	260-252-4	56539-66-3	Sub-chronic toxicity (90-day): oral	18/09/2014	03/11/2014	Details
bismuth hydroxide nitrate oxide	215-136-8	1304-85-4	Sub-chronic toxicity (90-day): oral	18/09/2014	03/11/2014	Details
bismuth oxide salicylate	238-953-1	14882-18-9	Sub-chronic toxicity (90 day): oral \|\| Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8)	18/09/2014	03/11/2014	Details
Isononanoic acid, C16-18 (even numbered)-alkyl esters	601-141-6	111937-03-2	Sub-chronic toxicity (90-day): oral	18/09/2014	03/11/2014	Details
Isononyl isononanoate	609-993-0	42131-25-9	Sub-chronic toxicity (90-day): oral	18/09/2014	03/11/2014	Details
l-Glutamic acid, N-coco acyl derivs., disodium salts	269-085-1	68187-30-4	Reproductive toxicity (pre-natal developmental toxicity)	18/09/2014	03/11/2014	Details
Linseed oil, polymerized	614-114-9	67746-08-1	Reproductive toxicity (pre-natal developmental toxicity)	18/09/2014	03/11/2014	Details
N,N'-hexane-1,6-diylbis(hexahydro-2-oxo-1H-azepine-1-carboxamide)	227-563-7	5888-87-9	Genetic toxicity in vivo	18/09/2014	03/11/2014	Details
Naphthenic acids, reaction products with diethylenetriamine	268-610-1	68131-13-5	Reproductive toxicity (pre-natal developmental toxicity)	18/09/2014	03/11/2014	Details
Poly[oxy(methyl-1,2-ethanediyl)], α,α'-(2,2-dimethyl-1,3-propanediyl)bis[ω-hydroxy-]	610-848-9	52479-58-0	Sub-chronic toxicity (90-day): oral	18/09/2014	03/11/2014	Details
praseodymium(III,IV) oxide	234-857-9	12037-29-5	Genetic toxicity in vivo	18/09/2014	03/11/2014	Details
Silsesquioxanes, phenyl	-	70131-69-0	Long-term toxicity to fish	18/09/2014	03/11/2014	Details
Condensation products of dimerised fatty acids, C18-unsaturated, with N,N-dimethyl-1,3-propanediamine and 1,3-propanediamine	605-296-0	162627-17-0	Sub-chronic toxicity (90 day): oral Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity)	14/08/2014 14/08/2014 14/08/2014	28/09/2014 28/09/2014 28/09/2014	Details
Ethanol, 2,2'-iminobis-, N-C12-18-alkyl derivs.	276-014-8	71786-60-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral Reproductive toxicity (two-generation reproductive toxicity)	14/08/2014 14/08/2014 14/08/2014	28/09/2014 28/09/2014 28/09/2014	Details
N-(2-hydroxypropyl)oleamide	203-828-2	111-05-7	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	14/08/2014 14/08/2014 14/08/2014	28/09/2014 28/09/2014 28/09/2014	Details

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