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Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Reaction mass of [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid and Phosphonic acid, P-[(tetrahydro-2-hydroxy-2-oxido-4H-1,4,2-oxazaphosphorin-4-yl)methyl]- 911-811-2 -
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/04/2015
17/04/2015
17/04/2015
04/06/2015
04/06/2015
04/06/2015
2,2-dimethyl-1,3-dioxolan-4-ylmethanol 202-888-7 100-79-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/04/2015
17/04/2015
04/06/2015
04/06/2015
[3-(triethoxysilyl)propyl]urea 245-876-7 23779-32-0
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/04/2015
17/04/2015
04/06/2015
04/06/2015
barium titanium trioxide 234-975-0 12047-27-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
17/04/2015
17/04/2015
04/06/2015
04/06/2015
Phosphoric acid, butyl ester 235-826-2 12788-93-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/04/2015
17/04/2015
04/06/2015
04/06/2015
(3-chloropropyl)diethoxymethylsilane 236-828-6 13501-76-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with (3-chloropropyl)triethoxysilane (CAS 5089-70-3) 17/04/2015 04/06/2015
(3-chloropropyl)dimethoxymethylsilane 242-056-0 18171-19-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6)” 17/04/2015 04/06/2015
(3E)-2-chloro-3-(hydroxymethylene)cyclohexene-1-carbaldehyde 801-656-8 1416808-92-8 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 17/04/2015 04/06/2015
2,2-dimethylpropan-1-ol, tribromo derivative 253-057-0 36483-57-5 Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015
2-ethyl-2-[[(1-oxononyl)oxy]methyl]propane-1,3-diyl dinonan-1-oate 204-793-6 126-57-8 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 17/04/2015 04/06/2015
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane 941-793-1 - Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-Propyn-1-ol, compd. with methyloxirane (EC 609-530-2, CAS 38172-91-7) 17/04/2015 04/06/2015
cerium trinitrate 233-297-2 10108-73-3 Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015
Reaction mass of potassium ethyl octylphosphonate and diethyl octylphosphonate 939-595-5 - Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015
Triethoxyoctylsilane 220-941-2 2943-75-1 Long-term toxicity to fish || Note: testing proposed with Triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1) 17/04/2015 04/06/2015
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-C13 odd-numbered alkyl) derivs. and sodium hydroxide and chloroacetic acid 938-645-3 -
Long-term toxicity to fish Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11 alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 271-794-6)
Sub-chronic toxicity (90-day): oral Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)
16/03/2015
16/03/2015
16/03/2015
30/04/2015
30/04/2015
30/04/2015
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and tetraethylenepentamine 500-289-8 103758-98-1
Reproductive toxicity (pre-natal developmental toxicity) ||Note: testing proposed with [Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine] (CAS 68082-29-1)
Sub-chronic toxicity (90-day): oral ||Note: testing proposed with [Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine] (CAS 68082-29-1)
16/03/2015
16/03/2015
30/04/2015
30/04/2015
tripotassium propylsilanetriolate 299-135-8 93857-00-2
Sub-chronic toxicity (90 day): inhalation Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7)
16/03/2015
16/03/2015
30/04/2015
30/04/2015
2-benzofuran-1,3-dione; 2-(2-hydroxyethoxy)ethanol 608-744-3 32472-85-8 Reproductive toxicity (pre-natal developmental toxicity) 16/03/2015 30/04/2015
3,5-bis(2,4-dimethylcyclohex-3-en-1-yl)polyheterocycle - - Genetic toxicity in vivo 16/03/2015 30/04/2015
dichlorocyclohexylmethylsilane 226-956-0 5578-42-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [dicyclopentyldimethoxysilane] (CAS 126990-35-0) 16/03/2015 30/04/2015
dipotassium heptafluorotantalate 240-986-1 16924-00-8 Genetic toxicity in vivo 16/03/2015 30/04/2015
Fatty acids, C16-18, reaction products with diethanolamine 293-014-3 91032-08-5 Reproductive toxicity (pre-natal developmental toxicity) 16/03/2015 30/04/2015
methylsilanetriyl triacetate 224-221-9 4253-34-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [Trimethoxy(methyl)silane] (EC 214-685-0) 16/03/2015 30/04/2015
tellurium dioxide 231-193-1 7446-07-3 Sub-chronic toxicity (90-day): oral 16/03/2015 30/04/2015
tert-butyl α,α-dimethylbenzyl peroxide 222-389-8 3457-61-2 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 16/03/2015 30/04/2015
4-methylmorpholine 4-oxide, monohydrate 231-391-8 7529-22-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
9-Octadecenoic acid (Z)-, sulfonated, potassium salts 271-843-1 68609-93-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
Benzene-1,2,4-tricarboxylic acid 1,2-anhydride, oligomeric reaction products with ethane-1,2-diol and glycerol 500-199-9 68183-39-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
reaction mass of bis(2,3-epoxypropyl) terephthalate and tris(oxiranylmethyl) benzene-1,2,4-tricarboxylate 940-592-6 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity)
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
(1,4-diazabicyclo[2.2.2]octane-2-yl)methanol 692-731-2 76950-43-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
16/02/2015
16/02/2015
02/04/2015
02/04/2015
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
16/02/2015
16/02/2015
02/04/2015
02/04/2015
Phosphorous acid, tri-C12-14-alkyl esters 297-701-9 93686-48-7
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
16/02/2015
16/02/2015
02/04/2015
02/04/2015
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane 219-784-2 2530-83-8 Genetic toxicity in vivo 16/02/2015 02/04/2015
bis(piperidinothiocarbonyl) hexasulphide 213-537-2 971-15-3 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 16/02/2015 02/04/2015
Polysulfides, di-tert-dodecyl 270-335-7 68425-15-0 Bioaccumulation aquatic / sediment 16/02/2015 02/04/2015
Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, reaction products with polyethylenepolyamines and tall-oil fatty acids, humates hydrochlorides 272-745-1 68910-55-4
Long-term toxicity to fish
Sub-chronic toxicity (90 day): inhalation
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
23/01/2015
23/01/2015
23/01/2015
23/01/2015
09/03/2015
09/03/2015
09/03/2015
09/03/2015
D-glucopyranose, oligomers, xylityl glycosides and 1,4 anhydro D-xylitol and D-xylitol 446-990-1 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
23/01/2015
23/01/2015
09/03/2015
09/03/2015
tetrahydro-2-methylfuran 202-507-4 96-47-9
Sub-chronic toxicity (90 day): inhalation
Reproductive toxicity (pre-natal developmental toxicity)
23/01/2015
23/01/2015
09/03/2015
09/03/2015
Aromatic hydrocarbons, C10-13, reaction products with branched nonene, sulfonated, sodium salts 800-660-7 1258274-08-6 Reproductive toxicity (pre-natal developmental toxicity) 23/01/2015 09/03/2015
Copper (2+), bis [N-{amino (imino-KN) methyl} urea-KO]-, nitrate (1:2) 800-038-5 1071838-81-7 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/01/2015 09/03/2015
tin monoxide 244-499-5 21651-19-4 Sub-chronic toxicity (90 day): inhalation 23/01/2015 09/03/2015
N,N'-bis(2,2,6,6-tetramethyl-4-piperidyl)isophthalamide 419-710-0 -
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
12/12/2014
12/12/2014
12/12/2014
26/01/2015
26/01/2015
26/01/2015
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide] 258-981-8 54112-23-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
12/12/2014
12/12/2014
26/01/2015
26/01/2015
N-(dimethylvinylsilyl)-1,1-dimethyl-1-vinylsilylamine 231-701-1 7691-02-3
Sub-chronic toxicity (90 day): inhalation “|| Note: Testing proposed with hexamethyldisilazane (CAS 999-97-3)”
Reproductive toxicity (pre-natal developmental toxicity) “|| Note: Testing proposed with hexamethyldisilazane (CAS 999-97-3)”
12/12/2014
12/12/2014
26/01/2015
26/01/2015
Reaction mass of ethoxylated (≥ 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate 939-702-5 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Ethoxylated bisphenol A diacrylate
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Ethoxylated bisphenol A diacrylate
12/12/2014
12/12/2014
26/01/2015
26/01/2015
(no public substance name available) 916-916-7 - Reproductive toxicity (pre-natal developmental toxicity) 12/12/2014 26/01/2015
1,1,1,3,5,5,5-heptamethyl-3-[(trimethylsilyl)oxy]trisiloxane 241-867-7 17928-28-8 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with decamethyltetrasiloxane (EC no. 205-491-7, CAS no. 141-62-8) 12/12/2014 26/01/2015
1,1,4,4-tetramethylbutane-1,4-diyl bis(2-ethylperoxyhexanoate) 235-935-5 13052-09-0 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 12/12/2014 26/01/2015
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers, reaction products with 2-butanone oxime 500-287-7 103170-26-9 Sub-chronic toxicity (90 day): inhalation 12/12/2014 26/01/2015
chlorodimethylvinylsilane 217-007-1 1719-58-0 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethylsilanol (CAS 1066-40-6) 12/12/2014 26/01/2015
Hexamethylene diisocyanate, oligomerisation product, blocked with 3,5-dimethyl-1H-pyrazole 605-318-9 163206-31-3 Sub-chronic toxicity (90 day): inhalation 12/12/2014 26/01/2015
Reaction mass of Amines, coco alkyl and β-Alanine, N-(2-carboxyethyl)-, N-coco alkyl derivs. and β-Alanine, N-coco alkyl derivs. 915-790-0 - Sub-chronic toxicity (90-day): oral 12/12/2014 26/01/2015
Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane 618-939-5 933999-84-9
Sub-chronic toxicity (90 day): dermal
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
18/11/2014
18/11/2014
18/11/2014
02/01/2015
02/01/2015
02/01/2015
Reaction mass of 2,2'-[(4-methylphenyl)imino]bisethanol and Ethanol 2-[[2-(2-hydroxyethoxy)ethyl](4-methylphenyl)amino]- 911-490-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Genetic toxicity in vivo
18/11/2014
18/11/2014
02/01/2015
02/01/2015
3,5-diamino-4-[[4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-2-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]benzoic acid sodium salt 480-890-9 906532-68-1 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 18/11/2014 02/01/2015
(no public substance name available) 434-430-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (two-generation reproductive toxicity)
16/10/2014
16/10/2014
16/10/2014
01/12/2014
01/12/2014
01/12/2014
2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo[d,g][1,3,2]dioxaphosphocin 6-oxide, sodium salt 286-344-4 85209-91-2
Long-term toxicity to fish
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
16/10/2014
16/10/2014
16/10/2014
01/12/2014
01/12/2014
01/12/2014
3-(triethoxysilyl)propanethiol 238-883-1 14814-09-6
Reproductive toxicity (pre-natal developmental toxicity)
Genetic toxicity in vivo
Sub-chronic toxicity (90-day): oral
16/10/2014
16/10/2014
16/10/2014
01/12/2014
01/12/2014
01/12/2014
triethoxy(3-thiocyanatopropyl)silane 252-161-3 34708-08-2
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/10/2014
16/10/2014
16/10/2014
01/12/2014
01/12/2014
01/12/2014
2-Oxepanone, polymer with 1,6-hexanediol 609-271-5 36609-29-7
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol
16/10/2014
16/10/2014
01/12/2014
01/12/2014
3,3-bis[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-1,5-divinyltrisiloxane 262-061-1 60111-54-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/10/2014
16/10/2014
01/12/2014
01/12/2014
Fatty acids, C18-unsatd., dimers, polymers with oleic acid and triethylenetetramine 614-339-2 68154-62-1
Sub-chronic toxicity (90-day): oral || Note: testing proposed with fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (EC 500-191-5, CAS 68082-29-1)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (EC 500-191-5, CAS 68082-29-1)
16/10/2014
16/10/2014
01/12/2014
01/12/2014
hexadecyltrimethoxysilane 240-464-3 16415-12-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/10/2014
16/10/2014
01/12/2014
01/12/2014
(chloromethyl)triethoxysilane 239-311-3 15267-95-5 Genetic toxicity in vivo 16/10/2014 01/12/2014
2-Propyn-1-ol, compd. with methyloxirane 609-530-2 38172-91-7 Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) 407-560-9 107934-68-9 Bioaccumulation aquatic / sediment || Note: Testing proposal is based on concern identified by the registrant. 16/10/2014 01/12/2014
decamethyltetrasiloxane 205-491-7 141-62-8 Reproductive toxicity (pre-natal developmental toxicity) 16/10/2014 01/12/2014
dichloro(3-chloropropyl)methylsilane 232-136-3 7787-93-1 Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6, CAS 5089-70-3) 16/10/2014 01/12/2014
dimethoxydimethylsilane 214-189-4 1112-39-6 Sub-chronic toxicity (90 day): inhalation 16/10/2014 01/12/2014
dimethoxymethylsilane 240-914-9 16881-77-9 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(methyl)silane. 16/10/2014 01/12/2014
Hexafluoropropene, oxidized, oligomers, reduced, fluorinated 500-537-5 161075-00-9 Bioaccumulation aquatic / sediment 16/10/2014 01/12/2014
hexahydrophthalic acid diglycidylester 696-026-0 1395383-69-3 Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014
Octadecylamine, reaction products with 4,4'-methylenediphenyl diisocyanate 928-226-3 - Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014
reaction mass of: triphenylthiophosphate and tertiary butylated phenyl derivatives 421-820-9 192268-65-8 Reproductive toxicity (pre-natal developmental toxicity) 16/10/2014 01/12/2014
triethoxy(methyl)silane 217-983-9 2031-67-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(methyl)silane. 16/10/2014 01/12/2014
undec-10-enoic acid 203-965-8 112-38-9 Long-term toxicity to fish 16/10/2014 01/12/2014
Esterification products of 4,4'-isopropylidenediphenol, ethoxylated and prop-2-enoic acid. 613-584-2 64401-02-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/09/2014
18/11/2014
03/11/2014
02/01/2015
1,3-diphenylpropane-1,3-dione 204-398-9 120-46-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
Genetic toxicity in vivo
18/09/2014
18/09/2014
18/09/2014
03/11/2014
03/11/2014
03/11/2014
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts 939-457-4 -
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/09/2014
18/09/2014
18/09/2014
03/11/2014
03/11/2014
03/11/2014
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts 939-455-3 -
Long-term toxicity to fish
Sub-chronic toxicity (90 day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/09/2014
18/09/2014
18/09/2014
03/11/2014
03/11/2014
03/11/2014
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene] 244-617-5 21850-44-2
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
1,4-diisopropylbenzene 202-826-9 100-18-5
Sub-chronic toxicity (90-day): oral || Note: testing proposed with CAS no. 99-62-7
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with CAS no. 99-62-7
18/09/2014
18/09/2014
03/11/2014
03/11/2014
2-amino-2-ethylpropanediol 204-101-2 115-70-8
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-amino-1,3-propanediol
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-amino-1,3-propanediol
18/09/2014
18/09/2014
03/11/2014
03/11/2014
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylated 614-503-3 68441-62-3
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed on rabbit.
Reproductive toxicity (two-generation reproductive toxicity)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with 2-methylimidazole 500-181-0 68002-42-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
4-methylthiosemicarbazide 229-563-2 6610-29-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
bismuth citrate 212-390-1 813-93-4
Sub-chronic toxicity (90-day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
fatty acids, C16 and C18 unsatd., polymers with bisphenol A, Bu glycidyl ether, epichlorohydrin and triethylenetetramine 600-687-2 105839-18-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
hex-3-yne-2,5-diol 221-209-5 3031-66-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
N-[3-(dimethylamino)propyl] C 12-C18 alkylamide 932-121-8 1147459-12-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
N-[3-(trimethoxysilyl)propyl]butylamine // Note: testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC No. 217-164-6) 250-437-8 31024-56-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
sodium O,O-diethyl dithiophosphate || Note: testing proposed with sodium O,O-diisobutyl dithiophosphate (EC 258-508-5) 222-079-2 3338-24-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate) 202-319-2 94-28-0 Reproductive toxicity (two-generation reproductive toxicity) 18/09/2014 03/11/2014
3-methoxy-3-methylbutan-1-ol 260-252-4 56539-66-3 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014
bismuth hydroxide nitrate oxide 215-136-8 1304-85-4 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014
bismuth oxide salicylate 238-953-1 14882-18-9 Sub-chronic toxicity (90 day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8) 18/09/2014 03/11/2014
Isononanoic acid, C16-18 (even numbered)-alkyl esters 601-141-6 111937-03-2 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014
Isononyl isononanoate 609-993-0 42131-25-9 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014
l-Glutamic acid, N-coco acyl derivs., disodium salts 269-085-1 68187-30-4 Reproductive toxicity (pre-natal developmental toxicity) 18/09/2014 03/11/2014
Linseed oil, polymerized 614-114-9 67746-08-1 Reproductive toxicity (pre-natal developmental toxicity) 18/09/2014 03/11/2014
N,N'-hexane-1,6-diylbis(hexahydro-2-oxo-1H-azepine-1-carboxamide) 227-563-7 5888-87-9 Genetic toxicity in vivo 18/09/2014 03/11/2014
Naphthenic acids, reaction products with diethylenetriamine 268-610-1 68131-13-5 Reproductive toxicity (pre-natal developmental toxicity) 18/09/2014 03/11/2014
Poly[oxy(methyl-1,2-ethanediyl)], α,α'-(2,2-dimethyl-1,3-propanediyl)bis[ω-hydroxy-] 610-848-9 52479-58-0 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014
praseodymium(III,IV) oxide 234-857-9 12037-29-5 Genetic toxicity in vivo 18/09/2014 03/11/2014
Silsesquioxanes, phenyl - 70131-69-0 Long-term toxicity to fish 18/09/2014 03/11/2014
Condensation products of dimerised fatty acids, C18-unsaturated, with N,N-dimethyl-1,3-propanediamine and 1,3-propanediamine 605-296-0 162627-17-0
Sub-chronic toxicity (90 day): oral
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
Ethanol, 2,2'-iminobis-, N-C12-18-alkyl derivs. 276-014-8 71786-60-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
Reproductive toxicity (two-generation reproductive toxicity)
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
N-(2-hydroxypropyl)oleamide 203-828-2 111-05-7
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
Perfluoroethane 200-939-8 76-16-4
Sub-chronic toxicity (90 day): inhalation
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
1,3,5-triazine-2,4,6(1H,3H,5H)-trithione, trisodium salt 241-749-5 17766-26-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
14/08/2014
14/08/2014
28/09/2014
28/09/2014
1,8-diazabicyclo[5.4.0]undec-7-ene 229-713-7 6674-22-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
2,2,6,6-tetramethyl-4-oxopiperidinooxy 220-778-7 2896-70-0
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2)
14/08/2014
14/08/2014
28/09/2014
28/09/2014
2-tert-butylphenol 201-807-2 88-18-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
14/08/2014
14/08/2014
28/09/2014
28/09/2014
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
[hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid, potassium salt 254-135-7 38820-59-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Benzenamine, N-phenyl-, reaction products with styrene and 2,4,4-trimethylpentene 272-940-1 68921-45-9
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with the smallest aryl- and alkyl-substituted materials
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the smallest aryl- and alkyl-substituted materials
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Benzophenone-3,3':4,4'-tetracarboxylic dianhydride 219-348-1 2421-28-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
14/08/2014
14/08/2014
28/09/2014
28/09/2014
N-(3-aminopropyl)iminodiethanol 225-642-0 4985-85-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Phosphoric acid, dodecyl ester, potassium salt 254-414-3 39322-78-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
α,α,α',α'-tetramethylxylene-α,α-diol 248-256-4 27138-01-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
14/08/2014
14/08/2014
28/09/2014
28/09/2014
(ethoxymethoxy)cyclododecane 261-332-1 58567-11-6 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
(Z)-N-octadec-9-enylhexadecan-1-amide 240-367-6 16260-09-6 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
1,4-diazabicyclooctane 205-999-9 280-57-9 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
1-(2-hydroxyethyl)pyrrolidin-2-one 222-359-4 3445-11-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
2,6,10,15,19,23-hexamethyltetracosane 203-825-6 111-01-3 Bioaccumulation aquatic / sediment 14/08/2014 28/09/2014
3,3,4,4,5,5,6,6,6-nonafluorohexene 243-053-7 19430-93-4 Sub-chronic toxicity (90 day): inhalation 14/08/2014 28/09/2014
3-methylbutanone 209-264-3 563-80-4 Sub-chronic toxicity (90 day): inhalation 14/08/2014 28/09/2014
6,15-dihydroanthrazine-5,9,14,18-tetrone 201-375-5 81-77-6 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
8,9,10,11-tetrachloro-12H-phthaloperin-12-one 244-007-9 20749-68-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
Copolymer of benzenamine and formaldehyde, hydrogenated 603-894-6 135108-88-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
Ethanol, 2,2'-iminobis-, N-(C13-15-branched and linear alkyl) derivs. 308-208-6 97925-95-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed on rabbits 14/08/2014 28/09/2014
Nerol 203-378-7 106-25-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt 939-650-3 - Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
Reaction mass of benzyl 2-ethylhexyl adipate and bis(2-ethylhexyl) adipate and dibenzyl adipate 905-983-8 - Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
Reaction mass of diisobutyl hydrogen phosphate and isobutyl dihydrogen phosphate 911-351-2 - Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
δ-valerolactone 208-807-1 542-28-9 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated 941-216-3 -
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distillation Residue 941-212-1 -
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distilled - -
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (two-generation reproductive toxicity)
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
m-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline 275-662-9 71604-74-5
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline 225-716-2 5026-74-4
Sub-chronic toxicity (90-day): oral || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Genetic toxicity in vivo || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline 225-716-2 5026-74-4
Sub-chronic toxicity (90-day): oral || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Genetic toxicity in vivo || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Sub-chronic toxicity (90 day): dermal
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
2,3-Epoxypropyl neodecanoate, oligomeric reaction products with toluene-4-sulfonic acid 500-281-4 98362-33-5
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
Addition products of m-phenylenebis(methylamine) with reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethyl 5-isocyanato-2-methylphenylcarbamate, 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-4-methylphenylcarbamate and 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-2-methylphenylcarbamate - -
Sub-chronic toxicity (90 day): oral
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on potential concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
1,1,3,3-tetramethylbutyl hydroperoxide 227-369-2 5809-08-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Biphenyl-4,4'-diol 202-200-5 92-88-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
15/07/2014
15/07/2014
29/08/2014
29/08/2014
bis(3,5,5-trimethylhexanoyl) peroxide 223-356-0 3851-87-4
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
15/07/2014
15/07/2014
29/08/2014
29/08/2014
bis(4-tert-butylcyclohexyl) peroxydicarbonate 239-557-1 15520-11-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Cashew, nutshell liq., oligomeric reaction products with 1-chloro-2,3-epoxypropane - 68413-24-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Diisopropylbenzene hydroperoxide 247-988-1 26762-93-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Quaternary ammonium compounds, C12-18-alkylbis(hydroxyethyl)methyl, chlorides 276-038-9 71808-53-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Reaction mass of (2-azaniumylethyl)[3-(trimethoxysilyl)propyl]amine chloride (2-azaniumylethyl)(benzyl)[3-(trimethoxysilyl)propyl]amine chloride 3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 7-benzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-10-ium chloride 10-benzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 7,10-dibenzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 700-961-2 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
tert-butyl α,α-dimethylbenzyl peroxide 222-389-8 3457-61-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Triethyl phosphonoacetate 212-757-6 867-13-0
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
15/07/2014
15/07/2014
29/08/2014
29/08/2014
1,3- and 1,4-cyclohexandicarboxyaldehyde 482-020-3 - Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014
2-(2H-benzotriazol-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol 274-570-6 70321-86-7 Bioaccumulation aquatic / sediment 15/07/2014 29/08/2014
2-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol 221-573-5 3147-75-9 Bioaccumulation aquatic / sediment 15/07/2014 29/08/2014
3,9-dicyclohex-3-enyl-2,4,8,10-tetraoxaspiro[5.5]undecane 229-542-8 6600-31-3 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014
6-tert-butyl-2,4-xylenol 217-533-1 1879-09-0 Long-term toxicity to fish 15/07/2014 29/08/2014
d-Glucose, ether with glycerol 309-496-6 100402-60-6 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014
Fatty acids, tall-oil, reaction products with formaldehyde and (Z)-N-9-octadecenyl-1,3-propanediamine 272-789-1 68911-83-1 Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on concern identified by the registrant. 15/07/2014 29/08/2014
Halophosphate - - Sub-chronic toxicity (90 day): inhalation 15/07/2014 29/08/2014
Poly [oxy(methyl-1,2-ethanediyl)] , a -hydro-w -hydroxy-, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1), 3-[[3-dimethylamino) propyl]imino]butanoate 613-645-3 646505-36-4 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014
Sodium xylenesulphonate 215-090-9 1300-72-7 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2014 29/08/2014
sodium/triethanolamine 4-((2-hydroxyethyl)amino)-3-pentaproenyl-4-oxobutanoate 800-765-8 1424149-03-0 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014
tert-butyl peroxyisobutyrate 203-650-5 109-13-7 Genetic toxicity in vivo 15/07/2014 29/08/2014
p-tert-butylphenyl 1-(2,3-epoxy)propyl ether 221-453-2 3101-60-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (two-generation reproductive toxicity)
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2014
17/06/2014
17/06/2014
17/06/2014
01/08/2014
01/08/2014
01/08/2014
01/08/2014
2-aminopropane-1,3-diol 208-584-0 534-03-2
Sub-chronic toxicity (90 day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2014
17/06/2014
01/08/2014
01/08/2014
Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane 915-748-1 -
Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with (CAS 211519-85-6)
Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with (CAS 211519-85-6)
17/06/2014
17/06/2014
01/08/2014
01/08/2014
Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda 939-368-0 -
Sub-chronic toxicity (90-day): inhalation
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2014
17/06/2014
01/08/2014
01/08/2014
tert-butyl peroxyneodecanoate 247-955-1 26748-41-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2014
17/06/2014
01/08/2014
01/08/2014
Trometamol 201-064-4 77-86-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-amino-1,3-propanediol
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-amino-1,3-propanediol
17/06/2014
17/06/2014
01/08/2014
01/08/2014
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Long-term toxicity to fish 17/06/2014 01/08/2014
Disodium oxybis[methylbenzenesulphonate] 277-242-0 73037-34-0 Reproductive toxicity (pre-natal developmental toxicity) 17/06/2014 01/08/2014
Hydroxyethylated 2-butyne-1,4-diol 608-711-3 32167-31-0 Sub-chronic toxicity (90-day): oral 17/06/2014 01/08/2014
Octene, hydroformylation products, low-boiling 273-110-1 68938-03-4 Genetic toxicity in vivo 17/06/2014 01/08/2014
Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride 800-430-6 1419212-76-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
05/06/2014
05/06/2014
21/07/2014
21/07/2014
Fatty acids, tall-oil, reaction products with fatty acids C16-C18 and C18-unsatd, branched and linear, diethylenetriamine and citric acid 806-510-7 1393571-43-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS number: 1419212-76-2, CAS name: Amides, tall-oil fatty, N, N’-(iminodi-2,1-ethanediyl)bis-, maleated)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS number: 1419212-76-2, CAS name: Amides, tall-oil fatty, N, N’-(iminodi-2,1-ethanediyl)bis-, maleated)
05/06/2014
05/06/2014
21/07/2014
21/07/2014
Fatty acids, tall-oil, reaction products with fatty acids C16-C18 and C18-unsatd, branched and linear, diethylenetriamine and maleic anhydride 806-508-6 1419212-77-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral Note: testing proposed with substance Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS: 1419212-76-2)
05/06/2014
05/06/2014
21/07/2014
21/07/2014
Fatty acids, C16-18 and C18-unsatd., branched and linear, reaction products with diethylenetriamine and tall-oil fatty acids, Me maleates 806-509-1 1393571-42-0 Reproductive toxicity (pre-natal developmental toxicity) 05/06/2014 21/07/2014
2-Butenedioic acid (Z)-, ester with 1,2-propanediol, compd. with 2-(dibutylamino)ethanol 286-304-6 85204-10-0
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (two-generation reproductive toxicity)
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
02/06/2014
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
17/07/2014
4,4'-Isopropylidenedicyclohexanol, oligomeric reaction products with 1-chloro-2,3-epoxypropane 500-070-7 30583-72-3
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
02/06/2014
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
17/07/2014
2-ethylhexyl benzoate 226-641-8 5444-75-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers 500-180-5 67989-52-0
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
Bis(2-chloroethoxy)methane 1,15-dichloro-3,5,8,11,13-penta-oxa pentadecane 1-(2-chloroethoxy)-2-(2-chloroethoxymethoxy)ethane 940-783-4 -
Long-term toxicity to fish
Genetic toxicity in vivo
Reproductive toxicity (two-generation reproductive toxicity) // Note: test to be performed with analogues substance 1-chloro-2-[(2-chloroethoxy)methoxy]ethane (EC 203-920-2 )
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
1,1,3,3-tetramethylbutyl peroxyneodecanoate 257-077-0 51240-95-0
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
02/06/2014
02/06/2014
17/07/2014
17/07/2014
2,2,4(or 2,4,4)-Trimethylhexane-1,6-diisocyanate 915-277-1 32052-51-0
Sub-chronic toxicity (90-day): inhalation
Reproductive toxicity (pre-natal developmental toxicity)
02/06/2014
02/06/2014
17/07/2014
17/07/2014
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine 939-485-7 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
02/06/2014
02/06/2014
17/07/2014
17/07/2014
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine acetate (1:1) 939-448-5 -
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)-
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)-
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Copolymer of acetonoxime and 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate 600-028-9 1001254-87-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): dermal
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Decene, hydroformylation products, high boiling 935-454-7 -
Sub-chronic toxicity (90-day): oral // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8)
Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8)
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Diisodecyl sebacate 249-047-0 28473-19-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Octene 246-920-8 25377-83-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with hex-1-ene
02/06/2014
02/06/2014
17/07/2014
17/07/2014
potassium tetrafluoroborate 237-928-2 14075-53-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol 939-719-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen 939-489-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
2-Propenoic acid, (1-methyl-1,2-ethanediyl) bis[oxy(methyl-2,1-ethanediyl)] ester, reaction products with diethylamine 601-101-8 111497-86-0 Reproductive toxicity (pre-natal developmental toxicity) 02/06/2014 17/07/2014
calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalenesulphonate) 939-717-7 - Sub-chronic toxicity (90-day): oral 02/06/2014 17/07/2014
Hydrocarbons, C14-C17, isoalkanes, cyclics, <2% aromatics 939-601-6 - Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with Icosane (C20 normal alkanes); Hydrocarbons, C14-C19, isoalkane, cyclics, < 2%; Hydrocarbon, C16-C20, normal, isoalkane, cyclics, 2-30% aromatics 02/06/2014 17/07/2014



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