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Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Fatty acids, C18-unsatd., dimers, reaction products with polyethylenepolyamines 614-452-7 68410-23-1
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Polysulfides, bis[3-(triethoxysilyl)propyl] 915-673-4 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Triethoxy(2,4,4-trimethylpentyl)silane 252-558-1 35435-21-3
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylateddehydrochlorinated, methoxylated 614-503-3 68441-62-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Alkenes, C11-12, hydroformylation products, distn. Residues 292-427-6 90622-27-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Aluminium oxide 215-691-6 1344-28-1 Genetic toxicity in vivo || Note: Testing proposal for two in vivo studies is based on concern identified by the registrant. Testing proposed with Aluminium oxide nanoscale material. 28/02/2018 16/04/2018
Bis(4-chlorophenyl) sulphone 201-247-9 80-07-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Calcium cyanamide 205-861-8 156-62-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Citral 226-394-6 5392-40-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Dihydrogen hexahydroxyplatinate 257-471-2 51850-20-5 Genetic toxicity in vivo || Note: Testing proposed with dihydrogen hexahydroxyplatinate(IV), compound with 2-aminoethanol (1:2). Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018
Dimethylamine 204-697-4 124-40-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides 295-714-4 92128-22-8 Reproductive toxicity (pre-natal developmental toxicity) 28/02/2018 16/04/2018
Hexahydro-4-methylphthalic anhydride 243-072-0 19438-60-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Reaction products of di-, tri- and tetra-propoxylated propane-1,2-diol with ammonia 618-561-0 - Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Tetraammineplatinum dichloride 237-706-5 13933-32-9 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018
Tetraammineplatinum dinitrate 243-929-9 20634-12-2 Genetic toxicity in vivo || Note: testing proposed with tetraammineplatinum(II) dichloride. Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018
Vinyl neononanoate 259-160-7 54423-67-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Polysulfides, di-tert-dodecyl 270-335-7 68425-15-0
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
31/01/2018
19/03/2018
19/03/2018
19/03/2018
2,4,6,8,10-pentamethylcyclopentasiloxane 228-204-7 6166-86-5
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4)
31/01/2018
31/01/2018
19/03/2018
19/03/2018


2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene 618-312-6 898566-17-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
19/03/2018
19/03/2018
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid 252-156-6 34690-00-1
Sub-chronic toxicity (90-day): oral || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Amines, polyethylenepoly-, tetraethylenepentamine fraction 292-587-7 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with TETA (CAS 90640-67-8) and HEPA (68121-73-7)
Reproductive toxicity (pre-natal developmental toxicity )
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Ashes (residues), plant 297-049-5 93333-79-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Ditetradecyl peroxydicarbonate 258-436-4 53220-22-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Potassium salts of {hexane-1,6-diylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1)  701-184-1 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Reaction products of pentaerythritol, propoxylated and 1-chloro-2,3-epoxypropane with hydrogen sulfide 701-196-7 -
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Biphenyl 202-163-5 92-52-4 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2018 19/03/2018
Everzol Red CDN Crude 483-940-8 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 31/01/2018 19/03/2018
Octadecanoic acid, sulfonated, potassium salt 701-179-4 - Sub-chronic toxicity (90-day): oral || Note: The List number has changed. 31/01/2018 19/03/2018
Pivalic acid 200-922-5 75-98-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (extended one-generation reproductive toxicity study)
20/12/2017
20/12/2017
20/12/2017
05/02/2018
05/02/2018
05/02/2018
2-(2-Vinyloxyethoxy)ethyl acrylate 451-690-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/12/2017
20/12/2017
05/02/2018
05/02/2018
pentaerythritol 204-104-9 115-77-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
20/12/2017
20/12/2017
05/02/2018
05/02/2018
Isotridecan-1-ol 248-469-2 27458-92-0 Reproductive toxicity (pre-natal developmental toxicity) 20/12/2017 05/02/2018
1,4-phenylene bis[(4-phenoxyphenyl)-methanone] 620-097-9 54299-17-1
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
22/11/2017
22/11/2017
08/01/2018
08/01/2018
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9
Sub-chronic toxicity (90-day): oral
-
22/11/2017
22/11/2017
08/01/2018
08/01/2017
3,6,9,12-tetraazatetradecamethylenediamine 223-775-9 4067-16-7
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7).
Reproductive toxicity (pre-natal developmental toxicity)
22/11/2017
22/11/2017
08/01/2018
08/01/2018
a,a-dimethylphenethyl butyrate 233-221-8 10094-34-5
Sub-chronic toxicity (90-day): oral“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)”
Reproductive toxicity (pre-natal developmental toxicity)“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)”
22/11/2017
22/11/2017
08/01/2018
08/01/2018
Amines, polyethylenepoly-, triethylenetetramine fraction 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/11/2017
22/11/2017
08/01/2018
08/01/2018


4-phenylbutan-2-one 219-847-4 2550-26-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a read-across substance having similar formula structure and its carbon chain consists of even number of carbons 22/11/2017 08/01/2018
Amines, polyethylenepoly- 268-626-9 68131-73-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 22/11/2017 08/01/2018
Glycerol, propoxylated, esters with acrylic acid 500-114-5 52408-84-1 Sub-chronic toxicity (90-day): oral 22/11/2017 08/01/2018
(-)-pin-2(3)-ene 232-077-3 7785-26-4 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017
2,2'-[hexane-1,6-diylbis(oxymethylene)]dioxirane 618-939-5 933999-84-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/10/2017 11/12/2017
4'-hydroxyacetophenone 202-802-8 99-93-4 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017
Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene 270-128-1 68411-46-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/10/2017 11/12/2017
Decamethylcyclopentasiloxane 208-764-9 541-02-6 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017
Geraniol 203-377-1 106-24-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/10/2017 11/12/2017
Slags, silicomanganese-manufg. 273-733-9 69012-33-5 Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with Slags, ferromanganese-manufg. CAS No 69012-28-8 (EC No 273-728-1) 25/10/2017 11/12/2017
tetraammine platinum (II) hydrogen carbonate 426-730-3 123439-82-7 Genetic toxicity in vivo|| Note: Testing proposed with tetraammineplatinum(II) dichloride. Testing proposal is based on concern identified by the registrant. 25/10/2017 11/12/2017
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane 500-107-7 40039-93-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/09/2017
27/09/2017
27/09/2017
13/11/2017
13/11/2017
13/11/2017
Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinonedimethylpropyl)anthraquinone 915-623-1 -
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
27/09/2017
27/09/2017
27/09/2017
13/11/2017
13/11/2017
13/11/2017
Triethoxyoctylsilane 220-941-2 2943-75-1
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/09/2017
27/09/2017
27/09/2017
13/11/2017
13/11/2017
13/11/2017
3-Ethenyl-5-methyl-2-oxazolidinone 809-852-5 3395-98-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/09/2017
27/09/2017
13/11/2017
13/11/2017
Trimethoxyoctylsilane 221-338-7 3069-40-7
Reproductive toxicity (extended one-generation reproductive toxicity study || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
27/09/2017
27/09/2017
13/11/2017
13/11/2017
Bisdecanoyl peroxide 212-092-1 762-12-9 Long-term toxicity to fish 27/09/2017 13/11/2017
Silver 231-131-3 7440-22-4 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with silver(1+) acetate (CAS number 563-63-3) 27/09/2017 13/11/2017
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate   940-272-6 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity
01/09/2017
01/09/2017
01/09/2017
16/10/2017
16/10/2017
16/10/2017
2,2'-iminodi(ethylamine) 203-865-4 111-40-0
Reproductive toxicity (extended one-generation reproductive toxicity study
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
3,5-dimethyl-1,2-dioxolane-3,5-diol 237-438-9 13784-51-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
3-trimethoxysilylpropyl methacrylate 219-785-8 2530-85-0
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene 939-009-8 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
1,1,3,3-tetramethylbutyl peroxyneodecanoate 257-077-0 51240-95-0 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant 01/09/2017 16/10/2017
2,2'-(octadec-9-enylimino)bisethanol 246-807-3 25307-17-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
2,2-dimethyl-3-oxopropyl acetate 811-188-6 16184-79-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 01/09/2017 16/10/2017
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
2-piperazin-1-ylethylamine 205-411-0 140-31-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
6-(isononanoylamino)hexanoic acid, compound with 2,2',2''-nitrilotriethanol (1:1) 701-138-0 242482-67-3 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017
Amines, polyethylenepoly- 268-626-9 68131-73-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
Dodecene, hydroformylation products, low-boiling 271-240-3 68526-92-1 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017
Menthol 201-939-0 89-78-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
Reaction mass of Ammonium bisethanedioato bisaquo niobate(V) (anhydrous form) and Ammonium hydrogen ethanedioate ethanedioic acid (anhydrous form 939-559-9 - Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017
Renewable hydrocarbons (diesel type fraction) 618-882-6 928771-01-1 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017
Terpineol 232-268-1 8000-41-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
potassium 4-cumenesulfonate 629-764-9 164524-02-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate  
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Reaction products of Isophorone diamine, Butyl  glycidyl ether, and Bisphenol A diglicydyl ether - -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Sodium p-cumenesulphonate 239-854-6 15763-76-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium (xylenes and 4-ethylbenzene) sulphonate
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Sodium toluene-4-sulphonate 211-522-5 657-84-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate 
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate 
22/06/2017
22/06/2017
07/08/2017
07/08/2017
tert-dodecanethiol 246-619-1 25103-58-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/06/2017
22/06/2017
07/08/2017
07/08/2017
(Z)-4-[C11-13(branched)alkylamino]-4-oxo-2-butenoic acid 701-116-0 84583-68-6 Sub-chronic toxicity (90-day): oral || Note: The previous EC number for the substance is 283-219-6. 22/06/2017 07/08/2017
2-Hydroxy-5-nonyl(branched)-benzaldehyde oxime 605-717-8 174333-80-3 Long-term toxicity to fish 22/06/2017 07/08/2017
Bis(dibutyldithiocarbamato-S,S')copper 237-695-7 13927-71-4 Long-term toxicity to fish 22/06/2017 07/08/2017
Dichloromethylbenzene 249-854-8 29797-40-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 22/06/2017 07/08/2017
Tetraammineplatinum (II) diacetate 457-310-8 - Genetic toxicity in vivo (COMET, OECD TG 489) || Note: Testing proposal is based on concern identified by the registrant. Testing proposed with Tetraammineplatinum dichloride (CAS 13933-32-9). 22/06/2017 07/08/2017
a,a-dimethylphenethyl acetate 205-781-3 151-05-3
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/05/2017
17/05/2017
03/07/2017
03/07/2017
potassium titanium oxide (K2Ti6O13) 432-240-0 12056-51-8 Long-term toxicity to fish 17/05/2017 03/07/2017
Trimethoxy(methyl)silane 214-685-0 1185-55-3
Reproductive toxicity (extended one-generation reproductive toxicity study
Reproductive toxicity (pre-natal developmental toxicity)
12/04/2017
12/04/2017
29/05/2017
29/05/2017
2-Butenoic acid, 4-oxo-4-(tridecylamino)-, (Z)-, branched 283-219-6 84583-68-6 Sub-chronic toxicity (90-day): oral 12/04/2017 29/05/2017
Condensation products of triethanolamine with addition products of fatty acids, C18 (unsaturated) alkyl with maleic anhydride - -
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
10/03/2017
10/03/2017
10/03/2017
25/04/2017
25/04/2017
25/04/2017
Methyl [3-(trimethoxysilyl)propyl]carbamate 245-659-7 23432-62-4
Genetic toxicity in vivo
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
10/03/2017
10/03/2017
10/03/2017
25/04/2017
25/04/2017
25/04/2017
Chloroethane 200-830-5 75-00-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
10/03/2017
10/03/2017
25/04/2017
25/04/2017
3-(Trimethoxysilyl)propyl (2E,4E)-hexa-2,4-dienoate 642-902-2 163802-53-7 Genetic toxicity in vivo 10/03/2017 25/04/2017
6-[(1-oxomethyloctyl)amino]hexanoic acid 276-173-3 71902-23-3 Reproductive toxicity (pre-natal developmental toxicity) 10/03/2017 25/04/2017
Fatty acids, tall-oil, reaction products with 2-[(2-aminoethyl)amino]ethanol 272-902-4 68919-76-6 Reproductive toxicity (pre-natal developmental toxicity) 10/03/2017 25/04/2017
Nitroethane 201-188-9 79-24-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with nitromethane (EC 200-876-6) 10/03/2017 25/04/2017
Reaction mass of 2-[[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]methyl]oxirane and 1,3-bis[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol and 1-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-3-[4-[[4-[3-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-2-hydroxy-propoxy]-3,5-dimethyl-phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol 941-357-0 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
08/02/2017
08/02/2017
27/03/2017
27/03/2017
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate  255-180-5 41026-17-9
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
16/12/2016
16/12/2016
16/12/2016
30/01/2017
30/01/2017
30/01/2017
Reaction products of polyaminoalkane and substituted octadecanoic acid 434-430-9 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
16/12/2016
16/12/2016
30/01/2016
30/01/2017
[3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane 220-780-8 2897-60-1 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 16/12/2016 30/01/2017
methyl-1h-benzotriazole 249-596-6 29385-43-1 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate 16/12/2016 30/01/2017
O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 Sub-chronic toxicity (90-day): oral 16/12/2016 30/01/2017
potassium 4-cumenesulfonate 629-764-9 164524-02-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) 16/12/2016 30/01/2017
sodium 1H-benzotriazolide 239-269-6 15217-42-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1H-Benzotriazole (EC 202-394-1) 16/12/2016 30/01/2017
Sodium 4(or 5)-methyl-1H-benzotriazolide 265-004-9 64665-57-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate 16/12/2016 30/01/2017
sodium cumenesulphonate 239-854-6 15763-76-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 16/12/2016 30/01/2017
sodium toluene-4-sulphonate 211-522-5 657-84-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) 16/12/2016 30/01/2017
Fatty acids, C14-18 and C16-18-unsatd., maleated - 85711-46-2
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
11/11/2016
11/11/2016
11/11/2016
03/01/2017
03/01/2017
03/01/2017
Reaction products of a polyol of pentaerythritol and propylene oxide, epichlorohydrin and hydrogen sulfide 615-735-8 72244-98-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity)
11/11/2016
11/11/2016
03/01/2017
03/01/2017
Trinonyl benzene-1,2,4-tricarboxylate 252-552-9 35415-27-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
11/11/2016
11/11/2016
03/01/2017
03/01/2017
((3-(sec-butyl)-4-(decyloxy)phenyl)methanetriyl)tribenzene 801-941-7 1404190-37-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
20/10/2016
20/10/2016
05/12/2016
05/12/2016
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 218-664-7 2212-81-9
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant
20/10/2016
20/10/2016
05/12/2016
05/12/2016
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione 276-763-0 72676-55-2 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 20/10/2016 05/12/2016
Bis(α,α-dimethylbenzyl) peroxide 201-279-3 80-43-3 Reproductive toxicity (pre-natal developmental toxicity 20/10/2016 05/12/2016
N-butyl-2,2,6,6-tetramethylpiperidin-4-amine 252-899-6 36177-92-1
Sub-chronic toxicity (90-day): ora
Reproductive toxicity (pre-natal developmental toxicity)
07/10/2016
07/10/2016
21/11/2016
21/11/2016
tert-pentyl hydroperoxide 222-321-7 3425-61-4
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
07/10/2016
07/10/2016
21/11/2016
21/11/2016
2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 260-829-0 57583-35-4
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity
01/09/2016
01/09/2016
01/09/2016
17/10/2016
17/10/2016
17/10/2016
Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts 270-608-0 68457-79-4
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2016
01/09/2016
01/09/2016
17/10/2016
17/10/2016
17/10/2016
4-hydroxy-4-methylpentan-2-one 204-626-7 123-42-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2016
01/09/2016
17/10/2016
17/10/2016
Sodium dihydrogenorthophosphate 231-449-2 7558-80-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2016 17/10/2016
cobalt dichloride 231-589-4 7646-79-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/07/2016
18/07/2016
01/09/2016
01/09/2016


1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives - - Sub-chronic toxicity (90-day): oral 30/06/2016 15/08/2016
boron orthophosphate - 13308-51-5 Reproductive toxicity (pre-natal developmental toxicity) 30/06/2016 15/08/2016
Fatty acids, tall-oil, di- and triesters with trimethylolpropane 941-376-4 -
Long-term toxicity to aquatic invertebrates
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
Testing proposed with EC No 931-531-4.
31/05/2016
31/05/2016
31/05/2016
15/07/2016
15/07/2016
15/07/2016
((3-(sec-butyl)-4-(decyloxy)phenyl)methanetriyl)tribenzene 801-941-7 1404190-37-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
31/05/2016
31/05/2016
15/07/2016
15/07/2016
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with maleic anhydride and methacrylic acid 500-090-6 36425-16-8
Sub-chronic toxicity (90-day): oral || Note: testing proposed with a structurally related substance (small vinyl ester)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a structurally related substance (small vinyl ester)
31/05/2016
31/05/2016
15/07/2016
15/07/2016
ASPHALT 232-490-9 8052-42-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/05/2016
31/05/2016
15/07/2016
15/07/2016
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, esters with acrylic acid 500-130-2 55818-57-0 Reproductive toxicity (pre-natal developmental toxicity) 31/05/2016 15/07/2016
ALCOHOLS, C11-14-ISO-, C13-RICH 271-235-6 68526-86-3 Sub-chronic toxicity (90-day): oral 31/05/2016 15/07/2016
ALCOHOLS, C7-9-ISO-, C8-RICH 271-231-4 68526-83-0 Sub-chronic toxicity (90-day): oral 31/05/2016 15/07/2016
Propylidynetrimethyl trimethacrylate 221-950-4 3290-92-4 Reproductive toxicity (pre-natal developmental toxicity) 31/05/2016 15/07/2016
Reaction mass of C18 (unsatd.) fatty acid amides/esters of diethanolamine, C16-18 (even-numbered) fatty amine (..) 943-172-0 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (extended one-generation reproductive toxicity study)
17/05/2016
17/05/2016
17/05/2016
01/07/2016
01/07/2016
01/07/2016
Melamine 203-615-4 108-78-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 17/05/2016 01/07/2016
Methylene-bis-4,1-(N-phenylene-N'-butylurea) 416-600-4 - Bioaccumulation aquatic / sediment 17/05/2016 01/07/2016
1,1,3,3-tetramethyldisiloxane 221-906-4 3277-26-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
29/04/2016
29/04/2016
13/06/2016
13/06/2016
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate 250-418-4 30989-05-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
29/04/2016
29/04/2016
13/06/2016
13/06/2016
N,N''-propane-1,3-diylbis[N'-octadecylurea 252-667-4 35674-65-8 Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) 29/03/2016 13/05/2016
1-isopropyl-2,2-dimethyltrimethylene diisobutyrate 229-934-9 6846-50-0 Reproductive toxicity (pre-natal developmental toxicity) 14/03/2016 28/04/2016
2,2'-(C16-18 (evennumbered, C18 unsaturated) alkyl imino) diethanol 620-540-6 1218787-32-6 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,2'-(Octadec-9-enylimino) bisethanol, CAS No 25307-17-9 14/03/2016 28/04/2016
Shale oils 269-646-0 68308-34-9 Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with Shale oils, heavy fractions (Registration No 01-2119756217-35-0000)” Sub-chronic toxicity (90-day): oral “|| Note: testing proposed with Shale oils, heavy fractions (Registration No 01-2119756217-35-0000)” 14/03/2016 28/04/2016
Shale oils, light 923-592-0 - Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” Sub-chronic toxicity (90-day): oral “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” 14/03/2016 28/04/2016
2,2-dimethylpropane-1,3-diyl dibenzoate 224-081-9 4196-89-8 Reproductive toxicity (pre-natal developmental toxicity) 29/02/2016 14/04/2016
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide 271-794-6 68608-66-2 Long-term toxicity to fish Sub-chronic toxicity (90-day): oral || Note: testing proposed with Reaction products of 1H-Imidazole- 1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0 29/02/2016 14/04/2016
N-butylbenzenesulphonamide 222-823-6 3622-84-2 Reproductive toxicity (pre-natal developmental toxicity) 29/02/2016 14/04/2016
2,2'-dimethyl-2,2'-azodipropiononitrile 201-132-3 78-67-1 Reproductive toxicity (pre-natal developmental toxicity) 03/02/2016 21/03/2016
2-(2-Ethoxyethoxy)-2-methylpropanee 257-196-8 51422-54-9 Sub-chronic toxicity (90 day): inhalation Reproductive toxicity (pre-natal developmental toxicity) 03/02/2016 21/03/2016
Esterification products of 4,4'-isopropylidenediphenol, ethoxylated and prop-2-enoic acid. 613-584-2 64401-02-1 Genetic toxicity in vivo 03/02/2016 21/03/2016
O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: Testing proposal is based on concern identified by the registrant.” 03/02/2016 21/03/2016
Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane 608-489-8 - Genetic toxicity in vivo 03/02/2016 21/03/2016
triethoxy(3-isocyanatopropyl)silane 246-467-6 24801-88-5 Genetic toxicity in vivo

Note: testing proposed with 3-(Trimethoxysilyl)propyl isocyanate (EC 239-415-9)
03/02/2016 21/03/2016
1,4-Cyclohexanedimethanol, reaction products with epichlorohydrin 600-447-7 1035218-79-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: Link to registration dossier not given as the dossier not yet disseminated
Sub-chronic toxicity (90 day): inhalation || Note: Link to registration dossier not given as the dossier not yet disseminated
23/12/2015
23/12/2015
03/02/2016
03/02/2016
Poly(oxy-1,2-ethanediyl), .alpha.-[3-[(carboxymethyl)methylamino]-2-hydroxypropyl]-.omega.-(4-nonylphenoxy)-, monosodium sal 616-248-3 75627-31-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity
23/12/2015
23/12/2015
03/02/2016
03/02/2016
Amines, tallow alkyl, dodecylbenzenesulfonates 268-766-0 68139-94-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity)
30/11/2015
30/11/2015
30/11/2015
14/01/2016
14/01/2016
14/01/2016
Formaldehyde, oligomeric reaction products with phenol and m-phenylenebis(methylamine) 500-137-0 57214-10-5
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
30/11/2015
30/11/2015
30/11/2015
14/01/2016
14/01/2016
14/01/2016
2,4-Pentanedione, peroxide 253-384-9 37187-22-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
30/11/2015
30/11/2015
14/01/2016
14/01/2016
Distilled tall oil, magnesium salts 939-629-9 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
30/11/2015
30/11/2015
14/01/2016
14/01/2016
Fatty acids, C18-unsatd., dimers, reaction products with polyethylenepolyamines 614-452-7 68410-23-1
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (CAS 68082-29-1)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (CAS 68082-29-1)
30/11/2015
30/11/2015
14/01/2016
14/01/2016
orthoboric acid, compound with 2,2'-iminodiethanol 267-886-0 67952-33-4
Sub-chronic toxicity (90-day): oral || Note: testing proposed with MEA Polyborate
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with MEA Polyborate
30/11/2015
30/11/2015
14/01/2016
14/01/2016
Reaction mass of (2S-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2R,4R) and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2S,4S) and (2R-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran 939-429-1 16409-43-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
30/11/2015
30/11/2015
14/01/2016
14/01/2016
(octadecanoato-O)oxoaluminium 236-521-7 13419-15-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Aluminum, benzoate C16-18 fatty acid complexes (CAS 94166-87-7) 30/11/2015 14/01/2016
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 248-227-6 27107-89-7 Genetic toxicity in vivo 30/11/2015 14/01/2016
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3 Reproductive toxicity (pre-natal developmental toxicity) 30/11/2015 14/01/2016
D-glucopyranose, oligomeric, C10-16 glycosides (even numbered), carboxymethyl ethers, sodium salts 609-542-8 383178-66-3 Reproductive toxicity (pre-natal developmental toxicity) 30/11/2015 14/01/2016
Fats and Glyceridic oils, vegetable, winterized, reaction products with ammonia-ethanolamine reaction products 800-253-4 - Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.

Link to registration dossier not given as the dossier not yet disseminated.
30/11/2015 14/01/2016
Hydrochloric acid, reaction products with aniline and nitrobenzene, sulfonated, sodium salts 291-454-0 90411-76-0 Reproductive toxicity (pre-natal developmental toxicity) 30/11/2015 14/01/2016
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide 806-543-7 215917-77-4 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 30/11/2015 14/01/2016
Reaction products of tryglycerides, C8-C18 (even numbered) and C18-unsaturated, glycerine and ethylene oxide 939-459-5 - Sub-chronic toxicity (90-day): oral 30/11/2015 14/01/2016
8,9,10-trinorborn-2-ene 207-866-0 498-66-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (extended one-generation reproductive toxicity study)
01/11/2015
01/11/2015
16/12/2015
16/12/2015
Amines, polyethylenepoly-, tetraethylenepentamine fraction 292-587-7 90640-66-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/11/2015 16/12/2015
N-vinylformamide 236-102-9 13162-05-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/11/2015 16/12/2015
N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) 204-613-6 123-26-2
Sub-chronic toxicity (90 day): oral
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with: “Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine”, CAS 100545-48-0
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates
30/09/2015
30/09/2015
30/09/2015
16/11/2015
16/11/2015
16/11/2015
Poly[oxy(methyl-1,2-ethanediyl)], a-hydro-omega-hydroxy-, ether with 2,6 bis{[(2-hydroxyethyl)amino]methyl}-4-nonylphenol 614-668-1 68610-97-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
30/09/2015
30/09/2015
16/11/2015
16/11/2015
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Sub-chronic toxicity (90-day): oral 30/09/2015 16/11/2015
dihydro-3-(tripropenyl)furan-2,5-dione 295-556-6 92077-08-2 Reproductive toxicity (pre-natal developmental toxicity) 30/09/2015 16/11/2015
sodium toluene-4-sulphonate 211-522-5 657-84-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 30/09/2015 16/11/2015
tetraethylammonium hydroxide 201-073-3 77-98-5 Sub-chronic toxicity (90-day): oral || Note: testing proposed with N,N,N-trimethylmethanaminium chloride (EC 200-880-8; CAS 75-57-0) 30/09/2015 16/11/2015
Esterification products of 4,4'-Isopropylidenediphenol, ethoxylated and prop-2-enoic acid and 3,5,5-trimethylhexanoic acide 919-846-5 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with an analogous substance
31/08/2015
31/08/2015
15/10/2015
15/10/2015
Tri(isopropyl)silyl acrylate 457-670-6 157859-20-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
31/08/2015
31/08/2015
15/10/2015
15/10/2015
Tri(isopropyl)silyl acrylate 457-670-6 157859-20-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
31/08/2015
31/08/2015
15/10/2015
15/10/2015
3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one 241-753-7 17772-51-9 Reproductive toxicity (pre-natal developmental toxicity) 31/08/2015 15/10/2015
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide] 258-981-8 54112-23-1 Long-term toxicity to fish
Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
31/08/2015 15/10/2015
trimethoxyoctylsilane 221-338-7 3069-40-7 Sub-chronic toxicity (90-day): oral || Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (CAS 35435-21-3) 07/08/2015 22/09/2015
Urea, N-octyl-N'-[4-[[4-[[(octylamino)carbonyl]amino]phenyl]methyl]phenyl]-Urea, N-[4-[[4[(octadecylamino)carbonyl]amino]phenyl]methyl]phenyl]-N’-octyl 445-760-8 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
31/07/2015
31/07/2015
14/09/2015
14/09/2015
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol 204-137-9 116-37-0 Reproductive toxicity (pre-natal developmental toxicity) 31/07/2015 14/09/2015
Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane 608-489-8 30499-70-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/06/2015
25/06/2015
25/06/2015
10/08/2015
10/08/2015
10/08/2015
1,1,1,3,5,5,5-heptamethyltrisiloxane 217-496-1 1873-88-7
Sub-chronic toxicity (90 day): inhalation
Note: testing proposed with 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7.
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Octamethyltrisiloxane, CAS 107-51-7 and 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7
25/06/2015
25/06/2015
10/08/2015
10/08/2015
1,1,3,3-tetramethyl-1,3-divinyldisiloxane 220-099-6 2627-95-4
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
4-trans-Propyl-4-trans-vinyl-[1,1-bicylohexyl] 601-409-2 116020-44-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
dichloro(diphenyl)silane 201-251-0 80-10-4
Sub-chronic toxicity (90-day): oral
Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
dimethoxydiphenylsilane 229-929-1 6843-66-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
N-[3-(dimethoxymethylsilyl)-2-methylpropyl]ethylenediamine 245-642-4 23410-40-4
Sub-chronic toxicity (90-day): oral
Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6)
Reproductive toxicity (pre-natal developmental toxicity)
Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
N-[3-(dimethoxymethylsilyl)propyl]ethylenediamine 221-336-6 3069-29-2
Sub-chronic toxicity (90-day): oral
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3.
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3.
25/06/2015
25/06/2015
10/08/2015
10/08/2015
Reaction mass of 6-Amino-5-(4-substituted-sulfophenylazo)-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt and 6-Amino-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-5-[sulfo- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt 445-040-3 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
Reaction mass of [[(2-hydroxyethyl)imino]dimethylene]bisphosphonic acid, sodium salt and 4-(Phosphonomethyl)-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane, sodium salt 939-513-8 -
Sub-chronic toxicity (90-day): oral
Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance
25/06/2015
25/06/2015
10/08/2015
10/08/2015
trichloro(hexadecyl)silane 227-575-2 5894-60-0
Sub-chronic toxicity (90-day): oral
Note: testing proposed with hexadecyl(trimethoxy)silane (EC 240-464-3, CAS 16415-12-6)
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with hexadecyl(trimethoxy)silane (EC 240-464-3, CAS 16415-12-6)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
Ureidopropyltrialkoxysilane 449-160-7 116912-64-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
1,1'-dithiobis[hexahydro-2H-azepin-2-one] 245-910-0 23847-08-7 Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015
A mixture of: cis-tetrahydro-2-isobutyl-4-methylpyran-4-ol; trans-tetrahydro-2-isobutyl-4-methylpyran-4-ol 405-040-6 63500-71-0 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2015 10/08/2015
Aluminum, benzoate C16-18-fatty acids complexes 303-385-6 94166-87-7 Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015
butan-2-one O,O',O''-(vinylsilylidyne)trioxime 218-747-8 2224-33-1 Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Butan-2-one O,O',O''-(methylsilylidyne)trioxime (CAS 22984-54-9).
25/06/2015 10/08/2015
dodecamethylpentasiloxane 205-492-2 141-63-9 Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Decamethyltetrasiloxane (EC 205-491-7).
25/06/2015 10/08/2015



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