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Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
cobalt dichloride 231-589-4 7646-79-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/07/2016
18/07/2016
01/09/2016
01/09/2016


Sodium dihydrogenorthophosphate 231-449-2 7558-80-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2016 17/10/2016
4-hydroxy-4-methylpentan-2-one 204-626-7 123-42-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2016
01/09/2016
17/10/2016
17/10/2016
2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 260-829-0 57583-35-4
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity
01/09/2016
01/09/2016
01/09/2016
17/10/2016
17/10/2016
17/10/2016
Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts 270-608-0 68457-79-4
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2016
01/09/2016
01/09/2016
17/10/2016
17/10/2016
17/10/2016
N-butyl-2,2,6,6-tetramethylpiperidin-4-amine 252-899-6 36177-92-1
Sub-chronic toxicity (90-day): ora
Reproductive toxicity (pre-natal developmental toxicity)
07/10/2016
07/10/2016
21/11/2016
21/11/2016
tert-pentyl hydroperoxide 222-321-7 3425-61-4
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
07/10/2016
07/10/2016
21/11/2016
21/11/2016
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione 276-763-0 72676-55-2 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 20/10/2016 05/12/2016
Bis(α,α-dimethylbenzyl) peroxide 201-279-3 80-43-3 Reproductive toxicity (pre-natal developmental toxicity 20/10/2016 05/12/2016
((3-(sec-butyl)-4-(decyloxy)phenyl)methanetriyl)tribenzene 801-941-7 1404190-37-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
20/10/2016
20/10/2016
05/12/2016
05/12/2016
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 218-664-7 2212-81-9
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant
20/10/2016
20/10/2016
05/12/2016
05/12/2016
Reaction products of a polyol of pentaerythritol and propylene oxide, epichlorohydrin and hydrogen sulfide 615-735-8 72244-98-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity)
11/11/2016
11/11/2016
03/01/2017
03/01/2017
Trinonyl benzene-1,2,4-tricarboxylate 252-552-9 35415-27-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
11/11/2016
11/11/2016
03/01/2017
03/01/2017
Fatty acids, C14-18 and C16-18-unsatd., maleated - 85711-46-2
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
11/11/2016
11/11/2016
11/11/2016
03/01/2017
03/01/2017
03/01/2017
[3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane 220-780-8 2897-60-1 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 16/12/2016 30/01/2017
methyl-1h-benzotriazole 249-596-6 29385-43-1 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate 16/12/2016 30/01/2017
O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 Sub-chronic toxicity (90-day): oral 16/12/2016 30/01/2017
potassium 4-cumenesulfonate 629-764-9 164524-02-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) 16/12/2016 30/01/2017
sodium 1H-benzotriazolide 239-269-6 15217-42-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1H-Benzotriazole (EC 202-394-1) 16/12/2016 30/01/2017
Sodium 4(or 5)-methyl-1H-benzotriazolide 265-004-9 64665-57-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate 16/12/2016 30/01/2017
sodium cumenesulphonate 239-854-6 15763-76-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 16/12/2016 30/01/2017
sodium toluene-4-sulphonate 211-522-5 657-84-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) 16/12/2016 30/01/2017
Reaction products of polyaminoalkane and substituted octadecanoic acid 434-430-9 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
16/12/2016
16/12/2016
30/01/2016
30/01/2017
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate  255-180-5 41026-17-9
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
16/12/2016
16/12/2016
16/12/2016
30/01/2017
30/01/2017
30/01/2017
Reaction mass of 2-[[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]methyl]oxirane and 1,3-bis[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol and 1-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-3-[4-[[4-[3-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-2-hydroxy-propoxy]-3,5-dimethyl-phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol 941-357-0 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
08/02/2017
08/02/2017
27/03/2017
27/03/2017
3-(Trimethoxysilyl)propyl (2E,4E)-hexa-2,4-dienoate 642-902-2 163802-53-7 Genetic toxicity in vivo 10/03/2017 25/04/2017
6-[(1-oxomethyloctyl)amino]hexanoic acid 276-173-3 71902-23-3 Reproductive toxicity (pre-natal developmental toxicity) 10/03/2017 25/04/2017
Fatty acids, tall-oil, reaction products with 2-[(2-aminoethyl)amino]ethanol 272-902-4 68919-76-6 Reproductive toxicity (pre-natal developmental toxicity) 10/03/2017 25/04/2017
Nitroethane 201-188-9 79-24-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with nitromethane (EC 200-876-6) 10/03/2017 25/04/2017
Chloroethane 200-830-5 75-00-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
10/03/2017
10/03/2017
25/04/2017
25/04/2017
Condensation products of triethanolamine with addition products of fatty acids, C18 (unsaturated) alkyl with maleic anhydride - -
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
10/03/2017
10/03/2017
10/03/2017
25/04/2017
25/04/2017
25/04/2017
Methyl [3-(trimethoxysilyl)propyl]carbamate 245-659-7 23432-62-4
Genetic toxicity in vivo
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
10/03/2017
10/03/2017
10/03/2017
25/04/2017
25/04/2017
25/04/2017
2-Butenoic acid, 4-oxo-4-(tridecylamino)-, (Z)-, branched 283-219-6 84583-68-6 Sub-chronic toxicity (90-day): oral 12/04/2017 29/05/2017
Trimethoxy(methyl)silane 214-685-0 1185-55-3
Reproductive toxicity (extended one-generation reproductive toxicity study
Reproductive toxicity (pre-natal developmental toxicity)
12/04/2017
12/04/2017
29/05/2017
29/05/2017
potassium titanium oxide (K2Ti6O13) 432-240-0 12056-51-8 Long-term toxicity to fish 17/05/2017 03/07/2017
a,a-dimethylphenethyl acetate 205-781-3 151-05-3
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/05/2017
17/05/2017
03/07/2017
03/07/2017
(Z)-4-[C11-13(branched)alkylamino]-4-oxo-2-butenoic acid 701-116-0 84583-68-6 Sub-chronic toxicity (90-day): oral || Note: The previous EC number for the substance is 283-219-6. 22/06/2017 07/08/2017
2-Hydroxy-5-nonyl(branched)-benzaldehyde oxime 605-717-8 174333-80-3 Long-term toxicity to fish 22/06/2017 07/08/2017
Bis(dibutyldithiocarbamato-S,S')copper 237-695-7 13927-71-4 Long-term toxicity to fish 22/06/2017 07/08/2017
Dichloromethylbenzene 249-854-8 29797-40-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 22/06/2017 07/08/2017
Tetraammineplatinum (II) diacetate 457-310-8 - Genetic toxicity in vivo (COMET, OECD TG 489) || Note: Testing proposal is based on concern identified by the registrant. Testing proposed with Tetraammineplatinum dichloride (CAS 13933-32-9). 22/06/2017 07/08/2017
potassium 4-cumenesulfonate 629-764-9 164524-02-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate  
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Reaction products of Isophorone diamine, Butyl  glycidyl ether, and Bisphenol A diglicydyl ether - -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Sodium p-cumenesulphonate 239-854-6 15763-76-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium (xylenes and 4-ethylbenzene) sulphonate
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Sodium toluene-4-sulphonate 211-522-5 657-84-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate 
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate 
22/06/2017
22/06/2017
07/08/2017
07/08/2017
tert-dodecanethiol 246-619-1 25103-58-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/06/2017
22/06/2017
07/08/2017
07/08/2017
1,1,3,3-tetramethylbutyl peroxyneodecanoate 257-077-0 51240-95-0 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant 01/09/2017 16/10/2017
2,2'-(octadec-9-enylimino)bisethanol 246-807-3 25307-17-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
2,2-dimethyl-3-oxopropyl acetate 811-188-6 16184-79-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 01/09/2017 16/10/2017
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
2-piperazin-1-ylethylamine 205-411-0 140-31-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
6-(isononanoylamino)hexanoic acid, compound with 2,2',2''-nitrilotriethanol (1:1) 701-138-0 242482-67-3 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017
Amines, polyethylenepoly- 268-626-9 68131-73-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
Dodecene, hydroformylation products, low-boiling 271-240-3 68526-92-1 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017
Menthol 201-939-0 89-78-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
Reaction mass of Ammonium bisethanedioato bisaquo niobate(V) (anhydrous form) and Ammonium hydrogen ethanedioate ethanedioic acid (anhydrous form 939-559-9 - Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017
Renewable hydrocarbons (diesel type fraction) 618-882-6 928771-01-1 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017
Terpineol 232-268-1 8000-41-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
2,2'-iminodi(ethylamine) 203-865-4 111-40-0
Reproductive toxicity (extended one-generation reproductive toxicity study
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
3,5-dimethyl-1,2-dioxolane-3,5-diol 237-438-9 13784-51-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
3-trimethoxysilylpropyl methacrylate 219-785-8 2530-85-0
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene 939-009-8 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate   940-272-6 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity
01/09/2017
01/09/2017
01/09/2017
16/10/2017
16/10/2017
16/10/2017
Bisdecanoyl peroxide 212-092-1 762-12-9 Long-term toxicity to fish 27/09/2017 13/11/2017
Silver 231-131-3 7440-22-4 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with silver(1+) acetate (CAS number 563-63-3) 27/09/2017 13/11/2017
3-Ethenyl-5-methyl-2-oxazolidinone 809-852-5 3395-98-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/09/2017
27/09/2017
13/11/2017
13/11/2017
Trimethoxyoctylsilane 221-338-7 3069-40-7
Reproductive toxicity (extended one-generation reproductive toxicity study || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
27/09/2017
27/09/2017
13/11/2017
13/11/2017
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane 500-107-7 40039-93-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/09/2017
27/09/2017
27/09/2017
13/11/2017
13/11/2017
13/11/2017
Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinonedimethylpropyl)anthraquinone 915-623-1 -
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
27/09/2017
27/09/2017
27/09/2017
13/11/2017
13/11/2017
13/11/2017
Triethoxyoctylsilane 220-941-2 2943-75-1
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/09/2017
27/09/2017
27/09/2017
13/11/2017
13/11/2017
13/11/2017
(-)-pin-2(3)-ene 232-077-3 7785-26-4 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017
2,2'-[hexane-1,6-diylbis(oxymethylene)]dioxirane 618-939-5 933999-84-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/10/2017 11/12/2017
4'-hydroxyacetophenone 202-802-8 99-93-4 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017
Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene 270-128-1 68411-46-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/10/2017 11/12/2017
Decamethylcyclopentasiloxane 208-764-9 541-02-6 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017
Geraniol 203-377-1 106-24-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/10/2017 11/12/2017
Slags, silicomanganese-manufg. 273-733-9 69012-33-5 Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with Slags, ferromanganese-manufg. CAS No 69012-28-8 (EC No 273-728-1) 25/10/2017 11/12/2017
tetraammine platinum (II) hydrogen carbonate 426-730-3 123439-82-7 Genetic toxicity in vivo|| Note: Testing proposed with tetraammineplatinum(II) dichloride. Testing proposal is based on concern identified by the registrant. 25/10/2017 11/12/2017
4-phenylbutan-2-one 219-847-4 2550-26-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a read-across substance having similar formula structure and its carbon chain consists of even number of carbons 22/11/2017 08/01/2018
Amines, polyethylenepoly- 268-626-9 68131-73-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 22/11/2017 08/01/2018
Glycerol, propoxylated, esters with acrylic acid 500-114-5 52408-84-1 Sub-chronic toxicity (90-day): oral 22/11/2017 08/01/2018
1,4-phenylene bis[(4-phenoxyphenyl)-methanone] 620-097-9 54299-17-1
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
22/11/2017
22/11/2017
08/01/2018
08/01/2018
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9
Sub-chronic toxicity (90-day): oral
-
22/11/2017
22/11/2017
08/01/2018
08/01/2017
3,6,9,12-tetraazatetradecamethylenediamine 223-775-9 4067-16-7
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7).
Reproductive toxicity (pre-natal developmental toxicity)
22/11/2017
22/11/2017
08/01/2018
08/01/2018
a,a-dimethylphenethyl butyrate 233-221-8 10094-34-5
Sub-chronic toxicity (90-day): oral“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)”
Reproductive toxicity (pre-natal developmental toxicity)“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)”
22/11/2017
22/11/2017
08/01/2018
08/01/2018
Amines, polyethylenepoly-, triethylenetetramine fraction 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/11/2017
22/11/2017
08/01/2018
08/01/2018


Isotridecan-1-ol 248-469-2 27458-92-0 Reproductive toxicity (pre-natal developmental toxicity) 20/12/2017 05/02/2018
2-(2-Vinyloxyethoxy)ethyl acrylate 451-690-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/12/2017
20/12/2017
05/02/2018
05/02/2018
pentaerythritol 204-104-9 115-77-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
20/12/2017
20/12/2017
05/02/2018
05/02/2018
Pivalic acid 200-922-5 75-98-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (extended one-generation reproductive toxicity study)
20/12/2017
20/12/2017
20/12/2017
05/02/2018
05/02/2018
05/02/2018
Biphenyl 202-163-5 92-52-4 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2018 19/03/2018
Everzol Red CDN Crude 483-940-8 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 31/01/2018 19/03/2018
Octadecanoic acid, sulfonated, potassium salt 701-179-4 - Sub-chronic toxicity (90-day): oral || Note: The List number has changed. 31/01/2018 19/03/2018
2,4,6,8,10-pentamethylcyclopentasiloxane 228-204-7 6166-86-5
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4)
31/01/2018
31/01/2018
19/03/2018
19/03/2018


2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene 618-312-6 898566-17-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
19/03/2018
19/03/2018
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid 252-156-6 34690-00-1
Sub-chronic toxicity (90-day): oral || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Amines, polyethylenepoly-, tetraethylenepentamine fraction 292-587-7 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with TETA (CAS 90640-67-8) and HEPA (68121-73-7)
Reproductive toxicity (pre-natal developmental toxicity )
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Ashes (residues), plant 297-049-5 93333-79-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Ditetradecyl peroxydicarbonate 258-436-4 53220-22-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Potassium salts of {hexane-1,6-diylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1)  701-184-1 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Reaction products of pentaerythritol, propoxylated and 1-chloro-2,3-epoxypropane with hydrogen sulfide 701-196-7 -
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Polysulfides, di-tert-dodecyl 270-335-7 68425-15-0
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
31/01/2018
19/03/2018
19/03/2018
19/03/2018
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylateddehydrochlorinated, methoxylated 614-503-3 68441-62-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Alkenes, C11-12, hydroformylation products, distn. Residues 292-427-6 90622-27-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Aluminium oxide 215-691-6 1344-28-1 Genetic toxicity in vivo || Note: Testing proposal for two in vivo studies is based on concern identified by the registrant. Testing proposed with Aluminium oxide nanoscale material. 28/02/2018 16/04/2018
Bis(4-chlorophenyl) sulphone 201-247-9 80-07-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Calcium cyanamide 205-861-8 156-62-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Citral 226-394-6 5392-40-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Dihydrogen hexahydroxyplatinate 257-471-2 51850-20-5 Genetic toxicity in vivo || Note: Testing proposed with dihydrogen hexahydroxyplatinate(IV), compound with 2-aminoethanol (1:2). Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018
Dimethylamine 204-697-4 124-40-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides 295-714-4 92128-22-8 Reproductive toxicity (pre-natal developmental toxicity) 28/02/2018 16/04/2018
Hexahydro-4-methylphthalic anhydride 243-072-0 19438-60-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Reaction products of di-, tri- and tetra-propoxylated propane-1,2-diol with ammonia 618-561-0 - Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Tetraammineplatinum dichloride 237-706-5 13933-32-9 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018
Tetraammineplatinum dinitrate 243-929-9 20634-12-2 Genetic toxicity in vivo || Note: testing proposed with tetraammineplatinum(II) dichloride. Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018
Vinyl neononanoate 259-160-7 54423-67-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
4-tert-butylpyrocatechol 202-653-9 98-29-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant.
28/02/2018
28/02/2018
16/04/2018
16/04/2018
ethyl methyl carbonate 433-480-9 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with an analogue substance.
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with an analogue substance.
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine 500-191-5 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Fatty acids, C18-unsatd., dimers, polymers with oleic acid and triethylenetetramine 701-120-2 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Fatty acids, C18-unsatd., dimers, reaction products with polyethylenepolyamines 614-452-7 68410-23-1
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Polysulfides, bis[3-(triethoxysilyl)propyl] 915-673-4 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Triethoxy(2,4,4-trimethylpentyl)silane 252-558-1 35435-21-3
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
C16-(branched), C20-(branched) and C24-(branched)-alkanes 700-992-1 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
28/02/2018
28/02/2018
28/02/2018
16/04/2018
16/04/2018
16/04/2018
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol 204-137-9 116-37-0 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
1,2,3,4-tetrahydronaphthalene 204-340-2 119-64-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. residues 271-832-1 68609-68-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
2,2'-[oxybis(methylene)]bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
2-chloropropane 200-858-8 75-29-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - Reproductive toxicity (pre-natal developmental toxicity) 26/03/2018 11/05/2018
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Sub-chronic toxicity (90-day): oral 26/03/2018 11/05/2018
Barium chloride 233-788-1 10361-37-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Bis(2-(2-butoxyethoxy)ethoxy)methane 205-598-9 143-29-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Dimethoxymethane 203-714-2 109-87-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Dipotassium hexachloroplatinate 240-979-3 16921-30-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 26/03/2018 11/05/2018
Hexachloroplatinic acid 241-010-7 16941-12-1 Genetic toxicity in vivo || Note: testing proposed with Diammonium hexachloroplatinate (EC 241-010-7). Testing proposal is based on concern identified by the registrant. 26/03/2018 11/05/2018
inorganic phosphorus salt 428-310-5 - Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Phenol, isopropylated, phosphate (3:1) 273-066-3 68937-41-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Slags, ferromanganese-manufg. 273-728-1 69012-28-8 Reproductive toxicity (pre-natal developmental toxicity) 26/03/2018 11/05/2018
2,4,4-trimethylpentene 246-690-9 25167-70-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity) || Note: There are two testing proposals for this endpoint.
26/03/2018
26/03/2018
11/05/2018
11/05/2018
2-methylpentane-2,4-diol 203-489-0 107-41-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
4,4'-methylenebis[2,6-diethylaniline] 237-185-4 13680-35-8
Long-term toxicity to fish
Genetic toxicity in vivo
26/03/2018
26/03/2018
11/05/2018
11/05/2018
alkyl amine and alkylbenzenesulphonate - -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Tris(2-butoxyethyl) phosphate 201-122-9 78-51-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione 401-540-3 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
26/03/2018
11/05/2018
11/05/2018
11/05/2018
(E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene 242-582-0 18794-84-8 Sub-chronic toxicity (90-day): oral 23/04/2018 07/06/2018
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. 272-221-2 68784-12-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol 204-327-1 119-47-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Alcohols, C18-22, distn. residues 641-136-6 1160164-88-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Benzoic acid, 2-hydroxy-, mono-C14-18-alkyl derivs., calcium salts (2:1) 931-276-9 - Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Decahydronaphthalene 202-046-9 91-17-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Diammonium hexachloroplatinate 240-973-0 16919-58-7 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/04/2018 07/06/2018
Dodecamethylcyclohexasiloxane 208-762-8 540-97-6 Reproductive toxicity (extended one-generation reproductive toxicity study 23/04/2018 07/06/2018
Hexadecyldimethylamine 695-101-5 1275611-65-8 Reproductive toxicity (pre-natal developmental toxicity) 23/04/2018 07/06/2018
Magnesium, bis(2-hydroxybenzoato-O1,O2)-, ar,ar'-di-C14-18alkyl derivs 931-371-5 - Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Octene, hydroformylation products, high-boiling 271-237-7 68526-89-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Potassium cyanate 209-676-3 590-28-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid 946-533-0 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) 23/04/2018 07/06/2018
Sulphamidic acid 226-218-8 5329-14-6 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with ammonium sulphamate (pH consideration) 23/04/2018 07/06/2018
Tetrahydrothiophene 1,1-dioxide 204-783-1 126-33-0 Reproductive toxicity (extended one-generation reproductive toxicity study) / Testing proposal is based on concern identified by the registrant. 23/04/2018 07/06/2018
4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane 260-350-7 56706-10-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Dihexadecyl peroxodicarbonate 247-611-0 26322-14-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity) || Note: Name of the substance on which testing is proposed to be carried out: ditetradecyl peroxydicarbonate (EC: 258-436-4)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
N-methylaniline 202-870-9 100-61-8
Sub-chronic toxicity (90 day): dermal
Reproductive toxicity (extended one-generation reproductive toxicity study)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Triethoxy(vinyl)silane 201-081-7 78-08-0
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2
Bioaccumulation aquatic / sediment
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
23/04/2018
23/04/2018
23/04/2018
07/06/2018
07/06/2018
07/06/2018
branched-nonyl 3,5,5 trimethylhexanoate 701-133-3 - Sub-chronic toxicity (90-day): oral || Note: previous EC no 609-993-0 21/05/2018 05/07/2018
Reaction mass of 1-[2-(2-aminobutoxy)ethoxy]but-2-ylamine and 1-({[2-(2-aminobutoxy)ethoxy]methyl}propoxy)but-2-ylamine 447-920-2 - Reproductive toxicity (pre-natal developmental toxicity) 21/05/2018 05/07/2018
1,4-Benzenedicarboxylic acid, mixed Bu and 2-ethylhexyl diesters 946-149-3 1571954-81-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
05/07/2018
05/07/2018
Ethylene dibenzoate 202-338-6 94-49-5
Reproductive toxicity (pre-natal developmental toxicity 
Developmental neurotoxicity
21/05/2018
21/05/2018
05/07/2018
05/07/2018
4,4'-Isopropylidenediphenol, ethoxylated 500-082-2 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
21/05/2018
05/07/2018
05/07/2018
05/07/2018
Methanal, reaction products with 1,3-bis(aminomethyl)benzene and hydroxybenzen 701-207-5 1950616-36-0
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
21/05/2018
05/07/2018
05/07/2018
05/07/2018
2-(2H-benzotriazol-2-yl)-p-cresol 219-470-5 2440-22-4 Bioaccumulation aquatic / sediment 18/06/2018 02/08/2018
Benzoic acid, 2-hydroxy-, mono-C>13-alkyl derivs., calcium salts (2:1) 281-018-8 83846-43-9 Sub-chronic toxicity (90-day): oral 18/06/2018 02/08/2018
Bumetrizole 223-445-4 3896-11-5 Bioaccumulation aquatic / sediment 18/06/2018 02/08/2018
Dipotassium tetrachloroplatinate 233-050-9 10025-99-7 Genetic toxicity in vivo || Note: "Testing proposal is based on concern identified by the registrant." 18/06/2018 02/08/2018
Isononanoic acid, C16-18 (even numbered)-alkyl esters 601-141-6 111937-03-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/06/2018 02/08/2018
Zinc, bis[O,O-bis(1-methylethyl) phosphorodithioato-.kappa.S]bis(cyclohexanamine)-, (T-4)- 809-986-4 52585-16-7 Genetic toxicity in vivo 18/06/2018 02/08/2018
Sodium 4-oxovalerate 243-378-4 19856-23-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/06/2018
18/06/2018
02/08/2018
02/08/2018
Tetra(isobutyl)thioperoxydicarbamic acid 221-312-5 3064-73-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/06/2018
18/06/2018
02/08/2018
02/08/2018
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-C12-14 acyl derivs., hydroxides, inner salts 293-878-1 91648-19-0
Long-term toxicity to fish || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-457-4)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)
18/06/2018
18/06/2018
18/06/2018
02/08/2018
02/08/2018
02/08/2018
3-methyldecane; benzene; cyclooctane; nonane 941-364-9 - Reproductive toxicity (extended one-generation reproductive toxicity study) 05/07/2018 20/08/2018
2,2'-azobis[2-methylpropionamidine] dihydrochloride 221-070-0 2997-92-4
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
05/07/2018
05/07/2018
20/08/2018
20/08/2018
Nonane-1,9-diol 223-517-5 3937-56-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
05/07/2018
05/07/2018
20/08/2018
20/08/2018
Ethane- 1,2-diol, propoxylated 500-078-0 31923-84-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
05/07/2018
05/07/2018
05/07/2018
20/08/2018
20/08/2018
20/08/2018
Propylidynetrimethanol, propoxylated 500-041-9 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with analogue substance
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with analogue substance
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with analogue substance
05/07/2018
05/07/2018
05/07/2018
20/08/2018
20/08/2018
20/08/2018
1-chloro-2,3-dimethylbenzene 480-880-4 608-23-1 Reproductive toxicity (pre-natal developmental toxicity) 10/08/2018 24/09/2018
2-(2-(2-butoxyethoxy)ethoxy)ethanol 205-592-6 143-22-6 Reproductive toxicity (pre-natal developmental toxicity) 10/08/2018 24/09/2018
C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters 701-257-8 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Sulfonic acids, C10-C21-alkane, Ph-esters (EC 293-728-5) 10/08/2018 24/09/2018
Oxydipropyl dibenzoate 248-258-5 27138-31-4 Long-term toxicity to fish 10/08/2018 24/09/2018
Peroxyacetic acid, reaction products with N2,N2’-1,6-hexanediylbis[N4,N6-dibutyl-N2,N4,N6-tris(2,2,6,6,tetramethyl-4-piperidinyl)-1,3,5-triazine-2,4,6-triamine, hydrogenated 812-927-5 1902936-62-2 Reproductive toxicity (pre-natal developmental toxicity) 10/08/2018 24/09/2018
Reaction mass of 2,7-Naphthalenedisulfonic acid, 5-amino-3-[[4-[2-[4-[(7-amino-1-hydroxy-3-sulfo-2-naphthalenyl)azo]-2-sulfophenyl]ethenyl]-3-sulfophenyl]azo]-4-hydroxy-, compd. with 2,2',2''-nitrilotris[ethanol] (1:5) and 3,3'-[ethylenebis[(3-sulpho-p-phenylene)azo]]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:6) and 3,3'-[vinylenebis[(3-sulpho-p-phenylene)azo]]bis[6-amino-4-hydroxynaphthalene-2-sulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:4) 916-899-6 - Sub-chronic toxicity (90-day): oral 10/08/2018 24/09/2018
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol 907-996-4 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) 10/08/2018 24/09/2018
Zinc bis(diethyldithiocarbamate) 238-270-9 14324-55-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 10/08/2018 24/09/2018
Allyl (cyclohexyloxy)acetate 272-657-3 68901-15-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/08/2018
10/08/2018
24/09/2018
24/09/2018
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 261-491-7 58909-56-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
10/08/2018
10/08/2018
10/08/2018
24/09/2018
24/09/2018
24/09/2018
3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 213-485-0 957-68-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
10/08/2018
10/08/2018
10/08/2018
24/09/2018
24/09/2018
24/09/2018
2-(2-thienyl)ethyl toluene-p-sulphonate 254-911-5 40412-06-4 Genetic toxicity in vivo 06/09/2018 22/10/2018
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Reproductive toxicity (pre-natal developmental toxicity) 06/09/2018 22/10/2018



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