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Predchádzajúce/výsledok

Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 

Further information

 

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Strana 6 z 10
200 Položiek na stránku
Zobrazuje sa 1 001 - 1 200 z 1 996 výsledkov.
Name
EC Number
CAS Number
Hazard endpoint for which vertebrate testing was proposed
Date of publication to call for available information
Deadline for submitting information
Alternatives to vertebrate testing
 
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate  255-180-5 41026-17-9
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2016
16/12/2016
16/12/2016
30/01/2017
30/01/2017
30/01/2017
 Details
1,3,5-tris[[4-tert-butyl-3-hydroxy-2,6-xylyl]methyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione 254-996-9 40601-76-1 Reproductive toxicity (pre-natal developmental toxicity) with Rat 24/07/2019 09/09/2019 Details
2-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]ethyl ethyl carbonate 254-959-7 40530-60-7 Genetic toxicity in vivo || Note: testing proposed with Disperse Red 302:1 (EC 248-882-8) 23/11/2020 07/01/2021 Details
2-(2-thienyl)ethyl toluene-p-sulphonate 254-911-5 40412-06-4 Genetic toxicity in vivo 06/09/2018 22/10/2018 Details
(2,4,6-trioxo-1,3,5-triazine-1,3,5(2H,4H,6H)-triyl)tri-2,1-ethanediyl triacrylate 254-843-6 40220-08-4 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020 Details
2-[2-(2-ethoxyethoxy)ethoxy]ethyl methacrylate 254-588-0 39670-09-2
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
30/06/2014
30/06/2014
 Details
Phosphoric acid, octadecyl ester 254-466-7 39471-52-8
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
17/04/2015
17/04/2015
04/06/2015
04/06/2015
04/06/2015
04/06/2015
 Details
Phosphoric acid, dodecyl ester, potassium salt 254-414-3 39322-78-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
 Details
(phenylethyl)benzene 254-179-7 38888-98-1 Reproductive toxicity (pre-natal developmental toxicity) 21/03/2014 05/05/2014 Details
[hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid, potassium salt 254-135-7 38820-59-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
 Details
1,1'-(p-tolylimino)dipropan-2-ol 254-075-1 38668-48-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/03/2016
17/04/2015
28/04/2016
04/06/2015
 Details
Sodium hydrogen N-(1-oxotetradecyl)-L-glutamate 253-981-4 38517-37-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with L-Glutamic acid, N-coco acyl derivs., disodium salts (CAS number: 68187-30-4; EC number: 269-085-1) || Note: Testing proposal is based on concern identified by the registrant. 17/12/2019 31/01/2020 Details
4,4'-[(isopropylidene)bis(p-phenyleneoxy)]diphthalic dianhydride 253-781-7 38103-06-9 Sub-chronic toxicity (90-day): oral 27/01/2020 12/03/2020 Details
2-phosphonobutane-1,2,4-tricarboxylic acid 253-733-5 37971-36-1
Long-term toxicity to fish||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3)
26/10/2022
26/10/2022
12/12/2022
12/12/2022
 Details
2,4-Pentanedione, peroxide 253-384-9 37187-22-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/11/2015
30/11/2015
14/01/2016
14/01/2016
 Details
2,2-dimethylpropan-1-ol, tribromo derivative 253-057-0 36483-57-5 Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015 Details
N-butyl-2,2,6,6-tetramethylpiperidin-4-amine 252-899-6 36177-92-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): ora
07/10/2016
07/10/2016
21/11/2016
21/11/2016
 Details
N,N''-propane-1,3-diylbis[N'-octadecylurea 252-667-4 35674-65-8 Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) 29/03/2016 13/05/2016 Details
Triethoxy(2,4,4-trimethylpentyl)silane 252-558-1 35435-21-3
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2011
29/04/2011
14/06/2011
14/06/2011
 Details
Triethoxy(2,4,4-trimethylpentyl)silane 252-558-1 35435-21-3
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
 Details
Trinonyl benzene-1,2,4-tricarboxylate 252-552-9 35415-27-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
11/11/2016
11/11/2016
03/01/2017
03/01/2017
 Details
Sodium 2-[(2-aminoethyl)amino]ethanesulphonate 252-173-9 34730-59-1 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2014 13/06/2014 Details
triethoxy(3-thiocyanatopropyl)silane 252-161-3 34708-08-2
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/10/2014
16/10/2014
16/10/2014
01/12/2014
01/12/2014
01/12/2014
 Details
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid 252-156-6 34690-00-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
Sub-chronic toxicity (90-day): oral || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
31/01/2018
31/01/2018
19/03/2018
19/03/2018
 Details
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid 252-156-6 34690-00-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral || Note: Testing proposal is based on concern identified by the registrant.
20/05/2015
20/05/2015
06/07/2015
06/07/2015
 Details
Tris(nitrato-O)nitrosylruthenium 252-068-8 34513-98-9 Genetic toxicity in vivo 01/07/2021 16/08/2021 Details
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide 252-046-8 34455-29-3 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide 252-046-8 34455-29-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
16/12/2020
16/12/2020
01/02/2021
01/02/2021
 Details
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate 252-029-5 34443-12-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
 Details
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate 252-029-5 34443-12-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
21/03/2014
05/05/2014
05/05/2014
05/05/2014
 Details
trimethoxy(2,4,4-trimethylpentyl)silane 251-995-5 34396-03-7 Long-term toxicity to fish 26/10/2022 12/12/2022 Details
trimethoxy(2,4,4-trimethylpentyl)silane 251-995-5 34396-03-7 Sub-chronic toxicity (90-day): oral
Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) " 		25/06/2015 10/08/2015 Details
Oleic acid, compound with (Z)-N-octadec-9-enylpropane-1,3-diamine (2:1) 251-846-4 34140-91-5
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
 Details
Sodium hexahydroxoantimonate 251-735-0 33908-66-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
29/08/2011
29/08/2011
 Details
1,2,3,5,6,7-hexahydro-1,1,2,3,3-pentamethyl-4H-inden-4-one 251-649-3 33704-61-9 Reproductive toxicity (pre-natal developmental toxicity) 30/06/2023 14/08/2023 Details
Diisononyl adipate 251-646-7 33703-08-1
Long-term toxicity to fish||Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1)
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1)
03/05/2023
03/05/2023
19/06/2023
19/06/2023
 Details
N,N-bis[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine 251-459-0 33329-35-0 Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with structurally-related compound 29/04/2014 13/06/2014 Details
3,4,5,6,7,8,9,10,11,12,13,14-dodecahydro-2H-cyclododeca[b]pyran 251-090-5 32539-83-6 Genetic toxicity in vivo 14/02/2011 31/03/2011 Details
Ethylene bis[3,3-bis(3-tert-butyl-4-hydroxyphenyl)butyrate] 251-073-2 32509-66-3 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2014 17/03/2014 Details
4-tert-butylcyclohexyl acetate 250-954-9 32210-23-4 Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with cis-4-tert-butylcyclohexyl acetate 		24/02/2020 09/04/2020 Details
Tris(2,4-ditert-butylphenyl) phosphite 250-709-6 31570-04-4 Reproductive toxicity (pre-natal developmental toxicity) 28/11/2022 12/01/2023 Details
Potassium 3-sulphonatopropyl acrylate 250-465-0 31098-20-1 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
N-[3-(trimethoxysilyl)propyl]butylamine // Note: testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC No. 217-164-6) 250-437-8 31024-56-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
 Details
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate 250-418-4 30989-05-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
29/04/2016
29/04/2016
13/06/2016
13/06/2016
 Details
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate 250-418-4 30989-05-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
28/02/2011
28/02/2011
28/02/2011
14/04/2011
14/04/2011
14/04/2011
 Details
2-isocyanatoethyl methacrylate 250-284-7 30674-80-7 Reproductive toxicity (pre-natal developmental toxicity) 23/03/2020 07/05/2020 Details
5-bromo-5-nitro-1,3-dioxane 250-001-7 30007-47-7 Genetic toxicity in vivo 19/10/2020 03/12/2020 Details
Isodecyl methacrylate 249-978-2 29964-84-9
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
03/10/2023
03/10/2023
17/11/2023
17/11/2023
 Details
Sodium hydrogen N-(1-oxododecyl)-L-glutamate 249-958-3 29923-31-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with CAS 68187-30-4 16/05/2014 30/06/2014 Details
Dichloromethylbenzene 249-854-8 29797-40-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 22/06/2017 07/08/2017 Details
Dichloromethylbenzene 249-854-8 29797-40-8 Reproductive toxicity (pre-natal developmental toxicity) 15/09/2011 31/10/2011 Details
Dichloromethylbenzene 249-854-8 29797-40-8 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2014 17/03/2014 Details
Isodecyl diphenyl phosphate 249-828-6 29761-21-5 Bioaccumulation aquatic / sediment 15/07/2011 29/08/2011 Details
Isooctyl acrylate 249-707-8 29590-42-9
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/03/2011
15/03/2011
29/04/2011
29/04/2011
 Details
methyl-1h-benzotriazole 249-596-6 29385-43-1 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate 16/12/2016 30/01/2017 Details
methyl-1h-benzotriazole 249-596-6 29385-43-1 Sub-chronic toxicity (90-day): oral 16/12/2020 01/02/2021 Details
4,4'-methylenebis[N,N-bis(2,3-epoxypropyl)aniline] 249-204-3 28768-32-3
Reproduction toxicity (two generation reproductive toxicity)
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity (90-day): dermal
26/01/2011
26/01/2011
26/01/2011
14/03/2011
14/03/2011
14/03/2011
 Details
Tetrasodium 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[(6-sulphonato-2-naphthyl)azo]naphthalene-2-sulphonate] 249-171-5 28706-25-4 Reproductive toxicity (pre-natal developmental toxicity) 10/05/2022 27/06/2022 Details
3-(isodecyloxy)propylammonium acetate 249-166-8 28701-67-9 Reproductive toxicity (pre-natal developmental toxicity) 26/08/2021 11/10/2021 Details
Zinc bis(O,O-diisooctyl) bis(dithiophosphate) 249-109-7 28629-66-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
04/10/2018
04/10/2018
04/10/2018
19/11/2018
19/11/2018
19/11/2018
 Details
Zinc bis(O,O-diisooctyl) bis(dithiophosphate) 249-109-7 28629-66-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5)
21/12/2021
21/12/2021
21/12/2021
04/02/2022
04/02/2022
04/02/2022
 Details
Di-''isononyl'' phthalate 249-079-5 28553-12-0 Reproductive toxicity (pre-natal developmental toxicity) 22/09/2022 07/11/2022 Details
Diisodecyl sebacate 249-047-0 28473-19-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
 Details
Ditolyl ether 248-948-6 28299-41-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/10/2021
21/10/2021
07/12/2021
07/12/2021
 Details
2-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]ethyl phenyl carbonate 248-882-8 28173-59-3 Genetic toxicity in vivo 23/11/2020 07/01/2021 Details
Benzyltoluene 248-654-8 27776-01-8 Long-term toxicity to fish (OECD 210) 25/06/2019 09/08/2019 Details
Benzyltoluene 248-654-8 27776-01-8 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2014 04/04/2014 Details
Vanadium oxide sulphate 248-652-7 27774-13-6
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium metavanadate (EC 237-272-7)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium metavanadate (EC 237-272-7)
01/04/2022
01/04/2022
16/05/2022
16/05/2022
 Details
Isotridecan-1-ol 248-469-2 27458-92-0 Reproductive toxicity (pre-natal developmental toxicity) 20/12/2017 05/02/2018 Details
Isotridecan-1-ol 248-469-2 27458-92-0 Reproductive toxicity (extended one-generation reproductive toxicity study) 16/12/2020 01/02/2021 Details
Neodecanoic acid, cobalt salt 248-373-0 27253-31-2 Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Neodecanoic acid, cobalt salt (EC no. 248-373-0) 28/11/2022 12/01/2023 Details
Neodecanoic acid, cobalt salt 248-373-0 27253-31-2 Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant 21/01/2021 08/03/2021 Details
2-ethylhexyl nitrate 248-363-6 27247-96-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
29/04/2011
29/04/2011
29/04/2011
14/06/2011
14/06/2011
14/06/2011
 Details
Nonene 248-339-5 27215-95-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
 Details
Oxydipropyl dibenzoate 248-258-5 27138-31-4 Long-term toxicity to fish 10/08/2018 24/09/2018 Details
α,α,α',α'-tetramethylxylene-α,α-diol 248-256-4 27138-01-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
 Details
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 248-227-6 27107-89-7
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2011
16/05/2011
16/05/2011
30/06/2011
30/06/2011
30/06/2011
 Details
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 248-227-6 27107-89-7 Genetic toxicity in vivo 30/11/2015 14/01/2016 Details
Octadecene 248-205-6 27070-58-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
 Details
Hexadecene 248-131-4 26952-14-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
 Details
Tetradecene 248-130-9 26952-13-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
 Details
Tricyclodecanedimethanol 248-096-5 26896-48-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
 Details
Diisopropylbenzene hydroperoxide 247-988-1 26762-93-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
 Details
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day)
26/05/2010
26/05/2010
26/05/2010
12/07/2010
12/07/2010
12/07/2010
 Details
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
 Details
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): dermal
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
 Details
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details
tert-butyl peroxyneodecanoate 247-955-1 26748-41-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2014
17/06/2014
01/08/2014
01/08/2014
 Details
Zinc bis[O-(2-ethylhexyl)] bis[O-(isobutyl)] bis(dithiophosphate) 247-810-2 26566-95-0
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with another ZDDP category member to be determined based on outcome of other testing proposals
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6)
21/12/2021
21/12/2021
21/12/2021
04/02/2022
04/02/2022
04/02/2022
 Details
Zinc bis[O-(2-ethylhexyl)] bis[O-(isobutyl)] bis(dithiophosphate) 247-810-2 26566-95-0
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
04/10/2018
04/10/2018
19/11/2018
19/11/2018
 Details
Octanoic acid, monoester with glycerol 247-668-1 26402-26-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/10/2023
03/10/2023
17/11/2023
17/11/2023
 Details
Dihexadecyl peroxodicarbonate 247-611-0 26322-14-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: Name of the substance on which testing is proposed to be carried out: ditetradecyl peroxydicarbonate (EC: 258-436-4)
Sub-chronic toxicity (90-day): oral
23/04/2018
23/04/2018
07/06/2018
07/06/2018
 Details
1,3,5-tris[3-(trimethoxysilyl)propyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione 247-465-8 26115-70-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/10/2023
03/10/2023
17/11/2023
17/11/2023
 Details
Bis(2-ethylhexyl) tetrabromophthalate 247-426-5 26040-51-7 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014 Details
Orthoboric acid, compound with 2-aminoethanol 247-421-8 26038-87-9 Repeated dose toxicity (90-day): oral 17/11/2011 02/01/2012 Details
Orthoboric acid, compound with 2-aminoethanol 247-421-8 26038-87-9
Long-term or reproductive toxicity to birds
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
 Details
N-(2-(4-amino-N-ethyl-m-toluidino)ethyl)methanesulphonamide sesquisulphate 247-161-5 25646-71-3 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
Dodecene 246-922-9 25378-22-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
 Details
Octene 246-920-8 25377-83-7
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with hex-1-ene
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
 Details
Tridecene 246-919-2 25377-82-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
 Details
Decene 246-870-7 25339-53-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
 Details
2,2'-(octadec-9-enylimino)bisethanol 246-807-3 25307-17-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017 Details
2,2`-(octadec-9-enylimino)bisethanol 246-807-3 25307-17-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
 Details
Tetrapropylenebenzene 246-772-4 25265-78-5
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
31/10/2011
31/10/2011
 Details
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol 246-771-9 25265-77-4 Reproductive toxicity (pre-natal developmental toxicity) 16/06/2011 01/08/2011 Details
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol 246-771-9 25265-77-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 22/09/2022 07/11/2022 Details
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol 246-771-9 25265-77-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/04/2019
26/04/2019
26/04/2019
10/06/2019
10/06/2019
10/06/2019
 Details
Hexene 246-768-2 25264-93-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Hex-1-ene (EC 209-753-1) || Note: testing proposed with Octadec-1-ene (EC 112-88-9) || Note: testing proposed with Hexadecene (EC 248-131-4) || Note: testing proposed with Alkenes, C8-10, C9-rich (EC 271-212-0) || Note: testing proposed with Nonene, branched (EC 306-492-6)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Hex-1-ene (EC 209-753-1) || Note: testing proposed with Octadec-1-ene (EC 112-88-9) || Note: testing proposed with Octadecene (EC 248-205-6) || Note: testing proposed with Alkenes, C8-10, C9-rich (EC 271-212-0) || Note: testing proposed with Nonene, branched (EC 306-492-6)
23/11/2020
23/11/2020
07/01/2021
07/01/2021
 Details
2,4,4-trimethylpentene 246-690-9 25167-70-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 15/07/2022 29/08/2022 Details
2,4,4-trimethylpentene 246-690-9 25167-70-8
Reproductive toxicity (pre-natal developmental toxicity) || Note: There are two testing proposals for this endpoint.
Sub-chronic toxicity (90-day): oral
26/03/2018
26/03/2018
11/05/2018
11/05/2018
 Details
Butene 246-689-3 25167-67-3
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
 Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/03/2012
06/03/2012
06/03/2012
20/04/2012
20/04/2012
20/04/2012
 Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3 Reproductive toxicity (pre-natal developmental toxicity) 30/11/2015 14/01/2016 Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 27/05/2019 11/07/2019 Details
Trixylyl phosphate 246-677-8 25155-23-1 Bioaccumulation aquatic / sediment 02/09/2011 17/10/2011 Details
1,2,3,6-tetrahydromethyl-3,6-methanophthalic anhydride 246-644-8 25134-21-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
03/11/2023
03/11/2023
18/12/2023
18/12/2023
 Details
tert-dodecanethiol 246-619-1 25103-58-6 Sub-chronic toxicity (90 day): inhalation 14/11/2013 30/12/2013 Details
tert-dodecanethiol 246-619-1 25103-58-6 Long-term toxicity to fish 16/06/2022 01/08/2022 Details
tert-dodecanethiol 246-619-1 25103-58-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/06/2017
22/06/2017
07/08/2017
07/08/2017
 Details
triethoxy(3-isocyanatopropyl)silane 246-467-6 24801-88-5 Genetic toxicity in vivo

Note: testing proposed with 3-(Trimethoxysilyl)propyl isocyanate (EC 239-415-9) 		03/02/2016 21/03/2016 Details
Triethoxy(3-isocyanatopropyl)silane 246-467-6 24801-88-5 Genetic toxicity in vivo 18/03/2021 03/05/2021 Details
Zinc bis(benzenesulphinate) 246-148-1 24308-84-7 Genetic toxicity in vivo 25/05/2020 09/07/2020 Details
N-[2-[(2-cyano-4,6-dinitrophenyl)azo]-5-(diethylamino)phenyl]acetamide 246-058-2 24170-60-3 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021 Details
1,1'-dithiobis[hexahydro-2H-azepin-2-one] 245-910-0 23847-08-7 Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015 Details
[3-(trimethoxysilyl)propyl]urea 245-904-8 23843-64-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Urea, N-(3-silylpropyl)-, Si-(ethoxy and methoxy) derivs., (EC 601-461-6) || Note: Testing proposal is based on concern identified by the registrant 07/07/2020 21/08/2020 Details
3,6,9,12-tetraoxotridecanol 245-883-5 23783-42-8 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1) 21/10/2021 07/12/2021 Details
[3-(triethoxysilyl)propyl]urea 245-876-7 23779-32-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
04/06/2015
04/06/2015
 Details
Methyl [3-(trimethoxysilyl)propyl]carbamate 245-659-7 23432-62-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/03/2017
10/03/2017
10/03/2017
25/04/2017
25/04/2017
25/04/2017
 Details
N-[3-(dimethoxymethylsilyl)-2-methylpropyl]ethylenediamine 245-642-4 23410-40-4
Reproductive toxicity (pre-natal developmental toxicity)
Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6)
Sub-chronic toxicity (90-day): oral
Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
 Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Long-term toxicity to fish 15/01/2024 29/02/2024 Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Reproductive toxicity (developmental toxicity) 26/01/2011 14/03/2011 Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Sub-chronic toxicity (90-day): oral 30/09/2015 16/11/2015 Details
2,2'-[OXYBIS(METHYLENE)]BIS[2-ETHYLPROPANE-1,3-DIOL] 245-509-0 23235-61-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2016
29/04/2016
13/06/2016
13/06/2016
 Details
2,2'-[oxybis(methylene)]bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Details
Tetraammonium ethylenediaminetetraacetate 245-022-3 22473-78-5 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
1,1,3,3-tetramethylbutyl 2-ethylperoxyhexanoate 244-894-2 22288-43-3 Genetic toxicity in vivo 10/05/2022 27/06/2022 Details
1,1,3,3-tetramethylbutyl 2-ethylperoxyhexanoate 244-894-2 22288-43-3 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014 Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene] 244-617-5 21850-44-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
 Details
tin monoxide 244-499-5 21651-19-4 Sub-chronic toxicity (90 day): inhalation 23/01/2015 09/03/2015 Details
6-(cyclohexylamino)-3-methyl-3H-dibenz[f,ij]isoquinoline-2,7-dione 244-320-0 21295-57-8 Genetic toxicity in vivo 26/08/2021 11/10/2021 Details
2-[(2-methyl-1-oxoallyl)oxy]ethyl acetoacetate 244-311-1 21282-97-3 Genetic toxicity in vivo 29/04/2014 13/06/2014 Details
2-tert-butyl-1,4-dimethoxybenzene 244-216-5 21112-37-8 Genetic toxicity in vivo 18/03/2021 03/05/2021 Details
Cobalt dihydroxide 244-166-4 21041-93-0
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
 Details
Cobalt dihydroxide 244-166-4 21041-93-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Diammonium dihydrogen ethylenediaminetetraacetate 244-063-4 20824-56-0 Sub-chronic toxicity (90 day): inhalation 29/07/2011 12/09/2011 Details
8,9,10,11-tetrachloro-12H-phthaloperin-12-one 244-007-9 20749-68-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
Disilver oxide 243-957-1 20667-12-3 Sub-chronic toxicity (90-day): oral 15/04/2011 30/05/2011 Details
Tetraammineplatinum dinitrate 243-929-9 20634-12-2 Genetic toxicity in vivo || Note: testing proposed with tetraammineplatinum(II) dichloride. Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018 Details
Sodium 4-oxovalerate 243-378-4 19856-23-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/06/2018
18/06/2018
02/08/2018
02/08/2018
 Details
Hexahydro-4-methylphthalic anhydride 243-072-0 19438-60-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Details
3,3,4,4,5,5,6,6,6-nonafluorohexene 243-053-7 19430-93-4 Sub-chronic toxicity (90 day): inhalation 14/08/2014 28/09/2014 Details
Potassium hexadecyl hydrogen phosphate 242-768-1 19035-79-1 Reproductive toxicity (pre-natal developmental toxicity) 20/05/2021 05/07/2021 Details
Octacos-1-ene 242-616-4 18835-34-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
 Details
Hexacos-1-ene 242-615-9 18835-33-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
 Details
(E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene 242-582-0 18794-84-8 Sub-chronic toxicity (90-day): oral 23/04/2018 07/06/2018 Details
3-hydroxy-2-(hydroxymethyl)-2-methylpropanal 242-393-3 18516-18-2
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
16/06/2011
16/06/2011
01/08/2011
01/08/2011
01/08/2011
01/08/2011
 Details
Strontium hydroxide 242-367-1 18480-07-4
Long-term toxicity to fish Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
15/04/2014
15/04/2014
15/04/2014
30/05/2014
30/05/2014
30/05/2014
 Details
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Reproductive toxicity (two-generation reproductive toxicity) 14/02/2011 31/03/2011 Details
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Reproductive toxicity (pre-natal developmental toxicity) 26/08/2021 11/10/2021 Details
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017 Details
(3-chloropropyl)dimethoxymethylsilane 242-056-0 18171-19-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6)” 17/04/2015 04/06/2015 Details
(3-chloropropyl)dimethoxymethylsilane 242-056-0 18171-19-2 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
1,1,1,3,5,5,5-heptamethyl-3-octyltrisiloxane 241-881-3 17955-88-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2020
17/06/2020
03/08/2020
03/08/2020
 Details
1,1,1,3,5,5,5-heptamethyl-3-[(trimethylsilyl)oxy]trisiloxane 241-867-7 17928-28-8 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with decamethyltetrasiloxane (EC no. 205-491-7, CAS no. 141-62-8) 12/12/2014 26/01/2015 Details
N-(cyclohexylthio)phthalimide 241-774-1 17796-82-6
Bioaccumulation: aquatic / sediment
Long-term or reproductive toxicity to birds
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
01/07/2011
01/07/2011
01/07/2011
01/07/2011
17/12/2012
15/08/2011
15/08/2011
15/08/2011
15/08/2011
31/01/2013
 Details
3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one 241-753-7 17772-51-9 Reproductive toxicity (pre-natal developmental toxicity) 31/08/2015 15/10/2015 Details
1,3,5-triazine-2,4,6(1H,3H,5H)-trithione, trisodium salt 241-749-5 17766-26-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
 Details
Sodium hydrogen m-sulphonatobenzoate 241-602-5 17625-03-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/04/2023
03/04/2023
22/05/2023
22/05/2023
 Details
N,N''-(4-methyl-m-phenylene)bis[N',N'-dimethylurea] 241-523-6 17526-94-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
23/03/2020
23/03/2020
07/05/2020
07/05/2020
 Details
3,4-dihydroxybenzonitrile 241-367-9 17345-61-8 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
Barium hydroxide 241-234-5 17194-00-2 Long-term toxicity to fish 29/04/2011 14/06/2011 Details
Barium hydroxide 241-234-5 17194-00-2 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Barium chloride dihydrate (EC 600-412-6) 16/12/2020 01/02/2021 Details
Barium hydroxide 241-234-5 17194-00-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/12/2011
16/12/2011
30/01/2012
30/01/2012
 Details
Hexachloroplatinic acid 241-010-7 16941-12-1 Genetic toxicity in vivo || Note: testing proposed with Diammonium hexachloroplatinate (EC 241-010-7). Testing proposal is based on concern identified by the registrant. 26/03/2018 11/05/2018 Details
dipotassium heptafluorotantalate 240-986-1 16924-00-8 Genetic toxicity in vivo 16/03/2015 30/04/2015 Details
Dipotassium hexachloroplatinate 240-979-3 16921-30-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 26/03/2018 11/05/2018 Details
Diammonium hexachloroplatinate 240-973-0 16919-58-7 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/04/2018 07/06/2018 Details
benzyl 3-isobutyryloxy-1-isopropyl-2,2-dimethylpropyl phthalate 240-920-1 16883-83-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/06/2011
16/06/2011
01/08/2011
01/08/2011
 Details
dimethoxymethylsilane 240-914-9 16881-77-9 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(methyl)silane. 16/10/2014 01/12/2014 Details
Dimethoxymethylsilane 240-914-9 16881-77-9 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
diammonium hexanitratocerate 240-827-6 16774-21-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cerium (III) nitrate (CAS 10294-41-4) 20/05/2015 06/07/2015 Details
Triethoxyhexadecylsilane 240-465-9 16415-13-7
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Hexadecyltrimethoxysilane (EC 240-464-3) || Note: Testing proposal is based on concern identified by the registrant
Sub-chronic toxicity (90-day): oral
07/07/2020
07/07/2020
21/08/2020
21/08/2020
 Details
hexadecyltrimethoxysilane 240-464-3 16415-12-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/11/2021
25/11/2021
10/01/2022
10/01/2022
 Details
hexadecyltrimethoxysilane 240-464-3 16415-12-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/10/2014
16/10/2014
01/12/2014
01/12/2014
 Details
hexadecyltrimethoxysilane 240-464-3 16415-12-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/05/2020 09/07/2020 Details
(Z)-N-octadec-9-enylhexadecan-1-amide 240-367-6 16260-09-6 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
Bis(2-ethylhexyl) peroxydicarbonate 240-282-4 16111-62-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
 Details
1,6-bis(2,3-epoxypropoxy)hexane 240-260-4 16096-31-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): dermal
15/03/2011
15/03/2011
15/03/2011
29/04/2011
29/04/2011
29/04/2011
 Details
1,6-bis(2,3-epoxypropoxy)hexane 240-260-4 16096-31-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): dermal
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
 Details
4,4,7,7-tetraethoxy-3,8-dioxa-4,7-disiladecane 240-212-2 16068-37-4
Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2020
17/06/2020
17/06/2020
17/06/2020
03/08/2020
03/08/2020
03/08/2020
03/08/2020
 Details
Triammonium hydrogen ethylenediaminetetraacetate 240-073-8 15934-01-7 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
2,2-bis[[(1-oxopentyl)oxy]methyl]propane-1,3-diyl divalerate 239-937-7 15834-04-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 21/10/2019 05/12/2019 Details
sodium cumenesulphonate 239-854-6 15763-76-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 16/12/2016 30/01/2017 Details
Sodium p-cumenesulphonate 239-854-6 15763-76-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium (xylenes and 4-ethylbenzene) sulphonate
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate
22/06/2017
22/06/2017
07/08/2017
07/08/2017
 Details
sodium p-cumenesulphonate 239-854-6 15763-76-5 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate 24/04/2015 12/06/2015 Details
bis(4-(1,1,3,3-tetramethylbutyl)phenyl)amine 239-816-9 15721-78-5
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
18/02/2014
04/04/2014
04/04/2014
04/04/2014
 Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate 239-701-3 15625-89-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/10/2022 12/12/2022 Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate 239-701-3 15625-89-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
25/05/2020
25/05/2020
09/07/2020
09/07/2020
 Details
2,2'-azobis[4-methoxy-2,4-dimethylvaleronitrile] 239-593-8 15545-97-8 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
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