Predchádzajúce/výsledok
Predchádzajúce/výsledok
Predchádzajúce/výsledok
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Octasodium 2,2'-[1,4-phenylenebis[imino(6-chloro-1,3,5-triazine-4,2-diyl)imino(1-hydroxy-3,6-disulphonatonaphthalene-2,8-diyl)azo]]bisnaphthalene-1,5-disulphonate | 275-108-6 | 71002-20-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant | 16/12/2020 | 01/02/2021 | Details | |
Octanoic acid, monoester with glycerol | 247-668-1 | 26402-26-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/10/2023 03/10/2023 |
17/11/2023 17/11/2023 |
Details | |
Octanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-1,3-propanediol and 3-(triethoxysilyl)-1-propanethiol | 485-270-1 | - | Genetic toxicity in vivo | 10/05/2022 | 27/06/2022 | Details | |
Octanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-1,3-propanediol and 3-(triethoxysilyl)-1-propanethiol | 485-270-1 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 12/01/2023 |
Details | |
Octamethyltrisiloxane | 203-497-4 | 107-51-7 | Reproductive toxicity (pre-natal developmental toxicity) | 03/03/2014 | 17/04/2014 | Details | |
Octadecylamine, reaction products with 4,4'-methylenediphenyl diisocyanate | 928-226-3 | - | Sub-chronic toxicity (90-day): oral | 16/10/2014 | 01/12/2014 | Details | |
Octadecene | 248-205-6 | 27070-58-2 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 |
Details | |
Octadecanoic acid, sulfonated, potassium salt | 701-179-4 | - | Sub-chronic toxicity (90-day): oral || Note: The List number has changed. | 31/01/2018 | 19/03/2018 | Details | |
Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine | 309-629-8 | 100545-48-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
Octadecanoic acid, 12-hydroxy-, reaction products with decanoic acid and ethylenediamine | 907-495-0 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
01/04/2022 01/04/2022 |
16/05/2022 16/05/2022 |
Details | |
Octadec-1-ene | 204-012-9 | 112-88-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
Octacos-1-ene | 242-616-4 | 18835-34-2 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 |
Details | |
Octabenzone | 217-421-2 | 1843-05-6 | Reproductive toxicity (pre-natal developmental toxicity) | 18/02/2013 | 04/04/2013 | Details | |
Octa-1,7-diene | 223-054-9 | 3710-30-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Oct-1-ene | 203-893-7 | 111-66-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
o-xylene | 202-422-2 | 95-47-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with p-xylene (EC 203-396-5) | 22/04/2021 | 07/06/2021 | Details | |
O-isopropyl ethylthiocarbamate | 205-517-7 | 141-98-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
o-cresol | 202-423-8 | 95-48-7 | Long-term toxicity to fish||Note: testing proposed with p-cresol (EC no. 203-398-6) | 10/05/2022 | 27/06/2022 | Details | |
o-(p-isocyanatobenzyl)phenyl isocyanate | 227-534-9 | 5873-54-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
O-(2-ethylhexyl) O,O-tert-pentyl peroxycarbonate | 274-919-2 | 70833-40-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
O-(2-ethylhexyl) O,O-tert-pentyl peroxycarbonate | 274-919-2 | 70833-40-8 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/10/2023 03/10/2023 03/10/2023 |
17/11/2023 17/11/2023 17/11/2023 |
Details | |
O,O-di(1-methylethyl)trithio-bis-thioformate,O,O-di(1-methylethyl)tetrathio-bis-thioformate,O,O-di(1-methylethyl)pentathio-bis-thioformate | 403-030-6 | - | Reproductive toxicity (pre-natal developmental toxicity) | 24/05/2013 | 08/07/2013 | Details | |
O,O,O-triphenyl phosphorothioate | 209-909-9 | 597-82-0 | Sub-chronic toxicity (90-day): oral | 16/12/2016 | 30/01/2017 | Details | |
O,O,O-triphenyl phosphorothioate | 209-909-9 | 597-82-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: Testing proposal is based on concern identified by the registrant.” | 03/02/2016 | 21/03/2016 | Details | |
Nonylphenol, branched, ethoxylated | 500-209-1 | 68412-54-4 | Reproductive toxicity (two-generation reproductive toxicity) | 29/07/2011 | 12/09/2011 | Details | |
Nonene | 248-339-5 | 27215-95-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
Nonanoic acid (branched), 2-oxiranylmethyl ester | 940-029-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) |
20/09/2013 20/09/2013 20/09/2013 |
04/11/2013 04/11/2013 04/11/2013 |
Details | |
Nonane-1,9-diol | 223-517-5 | 3937-56-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
Nonane-1,9-diol | 223-517-5 | 3937-56-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 |
Details | |
Nitromethane | 200-876-6 | 75-52-5 | Reproductive toxicity (pre-natal developmental toxicity) | 04/04/2014 | 19/05/2014 | Details | |
Nitroethane | 201-188-9 | 79-24-3 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with nitromethane (EC 200-876-6) | 10/03/2017 | 25/04/2017 | Details | |
Nickel, 5,5'-azobis-2,4,6(1H,3H,5H)-pyrimidinetrione complexes and melamine | 939-379-0 | - | Reproductive toxicity (pre-natal developmental toxicity) | 04/04/2014 | 19/05/2014 | Details | |
Nickel | 231-111-4 | 7440-02-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2019 | 15/04/2019 | Details | |
Nerol | 203-378-7 | 106-25-2 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Neodecanoic acid, cobalt salt | 248-373-0 | 27253-31-2 | Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant | 21/01/2021 | 08/03/2021 | Details | |
Neodecanoic acid, cobalt salt | 248-373-0 | 27253-31-2 | Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Neodecanoic acid, cobalt salt (EC no. 248-373-0) | 28/11/2022 | 12/01/2023 | Details | |
Naphthenic acids, reaction products with diethylenetriamine | 268-610-1 | 68131-13-5 | Reproductive toxicity (pre-natal developmental toxicity) | 18/09/2014 | 03/11/2014 | Details | |
Naphthenic acids | 215-662-8 | 1338-24-5 | Long-term toxicity to fish | 01/07/2011 | 15/08/2011 | Details | |
Naphthenic acids | 215-662-8 | 1338-24-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
04/04/2014 04/04/2014 |
19/05/2014 19/05/2014 |
Details | |
Naphthalene-2,6-dicarboxylic acid | 214-527-0 | 1141-38-4 | Reproductive toxicity (pre-natal developmental toxicity) | 16/06/2022 | 01/08/2022 | Details | |
Naphtha (petroleum), steam-cracked middle arom. | 271-138-9 | 68516-20-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Sub-chronic toxicity (90-day): oral
|| Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) |
22/04/2021 22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 07/06/2021 |
Details | |
n4,n4'-hexane-1,6-diylbis[n-butyl-6-chloro-n,n'-bis(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,5-triazine-2,4-diamine] | 835-183-3 | 83420-16-0 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/09/2021 30/09/2021 30/09/2021 |
15/11/2021 15/11/2021 15/11/2021 |
Details | |
N1,N3‐bis(3‐methylphenyl)‐5‐[(3‐methylphenyl)sulfamoyl]benzene‐1,3‐dicarboxamide | 951-483-8 | 2375645-78-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2022 16/06/2022 16/06/2022 |
01/08/2022 01/08/2022 01/08/2022 |
Details | |
N-{3-[C12-14-(even numbered)-alkyloxy]propyl}propane-1,3-diamine | 701-437-6 | - | Sub-chronic toxicity (90-day): oral|| Note: testing proposed with [1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC no 931-295-2) | 15/07/2022 | 29/08/2022 | Details | |
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide | 806-543-7 | 215917-77-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
24/02/2020 24/02/2020 |
09/04/2020 09/04/2020 |
Details | |
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide | 806-543-7 | 215917-77-4 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 30/11/2015 | 14/01/2016 | Details | |
N-vinylformamide | 236-102-9 | 13162-05-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/11/2015 | 16/12/2015 | Details | |
N-vinylformamide | 236-102-9 | 13162-05-5 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
01/07/2011 01/07/2011 |
15/08/2011 15/08/2011 |
Details | |
N-phenylmaleimide | 213-382-0 | 941-69-5 | Genetic toxicity in vivo | 29/04/2011 | 14/06/2011 | Details | |
N-phenyl-N-[(trichloromethyl)thio]benzenesulphonamide | 218-915-0 | 2280-49-1 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
N-Phenyl-diethanolamine, reaction products with formaldehyde | 942-131-4 | - | Reproductive toxicity (pre-natal developmental toxicity) | 21/10/2021 | 07/12/2021 | Details | |
N-Phenyl-diethanolamine, reaction products with formaldehyde | 942-131-4 | - | Genetic toxicity in vivo | 26/08/2021 | 11/10/2021 | Details | |
N-pentan-2-ylidenehydroxylamine | 484-470-6 | 623-40-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
20/05/2021 20/05/2021 |
05/07/2021 05/07/2021 |
Details | |
N-octadecylstearamide | 236-276-6 | 13276-08-9 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) |
17/04/2015 17/04/2015 17/04/2015 |
04/06/2015 04/06/2015 04/06/2015 |
Details | |
N-methylaniline | 202-870-9 | 100-61-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90 day): dermal |
23/04/2018 23/04/2018 |
07/06/2018 07/06/2018 |
Details | |
N-methylaniline | 202-870-9 | 100-61-8 |
Long-term or reproductive toxicity to birds Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): dermal |
01/07/2011 01/07/2011 01/07/2011 01/07/2011 |
15/08/2011 15/08/2011 15/08/2011 15/08/2011 |
Details | |
n-methyl-n-[c18-(unsaturated)alkanoyl]glycine | 701-177-3 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2021 | 07/12/2021 | Details | |
N-isopropylhydroxylamine | 225-791-1 | 5080-22-8 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 04/04/2014 |
Details | |
N-ethyl-2-pyrrolidone (NEP) | 220-250-6 | 2687-91-4 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day) via the inhalatory route |
26/01/2011 26/01/2011 |
14/03/2011 14/03/2011 |
Details | |
n-butyltin trichloride | 214-263-6 | 1118-46-3 | Reproductive toxicity (pre-natal developmental toxicity) | 29/04/2011 | 14/06/2011 | Details | |
N-butylbenzenesulphonamide | 222-823-6 | 3622-84-2 | Reproductive toxicity (pre-natal developmental toxicity) | 29/02/2016 | 14/04/2016 | Details | |
N-butylbenzenesulphonamide | 222-823-6 | 3622-84-2 | Reproductive toxicity (pre-natal developmental toxicity) | 14/02/2011 | 31/03/2011 | Details | |
N-butyl-2,2,6,6-tetramethylpiperidin-4-amine | 252-899-6 | 36177-92-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): ora |
07/10/2016 07/10/2016 |
21/11/2016 21/11/2016 |
Details | |
N-butyl phenyl ether | 214-426-1 | 1126-79-0 | Long-term toxicity to fish | 03/04/2023 | 22/05/2023 | Details | |
N-butyl 4-oxopentanoate | 218-143-4 | 2052-15-5 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Levulinic acid (EC 204-649-2) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Levulinic acid (EC 204-649-2) |
23/11/2020 23/11/2020 |
07/01/2021 07/01/2021 |
Details | |
N-benzyl-N-C16-18 (even numbered)-alkyl-N-methyl-C16-18 (even numbered)-alkyl-1-aminium chloride | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
N-acetylhexanelactam | 217-565-6 | 1888-91-1 | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant | 17/06/2020 | 03/08/2020 | Details | |
N-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]-2-methyl-prop-2-enamide | 611-915-5 | 59941-98-9 | Genetic toxicity in vivo | 22/04/2021 | 07/06/2021 | Details | |
N-[3-(trimethoxysilyl)propyl]butylamine // Note: testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC No. 217-164-6) | 250-437-8 | 31024-56-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
N-[3-(dimethylamino)propyl]methacrylamide | 226-002-3 | 5205-93-6 | Reproductive toxicity (pre-natal developmental toxicity) | 29/04/2011 | 14/06/2011 | Details | |
N-[3-(dimethylamino)propyl] C 12-C18 alkylamide | 932-121-8 | 1147459-12-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
N-[3-(dimethoxymethylsilyl)propyl]ethylenediamine | 221-336-6 | 3069-29-2 |
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3. Sub-chronic toxicity (90-day): oral
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3. |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
N-[3-(dimethoxymethylsilyl)-2-methylpropyl]ethylenediamine | 245-642-4 | 23410-40-4 |
Reproductive toxicity (pre-natal developmental toxicity) Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6) Sub-chronic toxicity (90-day): oral Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6) |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
N-[2-[(2-cyano-4,6-dinitrophenyl)azo]-5-(diethylamino)phenyl]acetamide | 246-058-2 | 24170-60-3 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 23/11/2020 | 07/01/2021 | Details | |
N-[2-[(2-bromo-4,6-dinitrophenyl)azo]-5-(diallylamino)-4-methoxyphenyl]acetamide | 257-486-4 | 51868-46-3 | Genetic toxicity in vivo | 26/10/2022 | 12/12/2022 | Details | |
N-[2-(piperazin-1-yl)ethyl]C18-unsatured-alkylamide | 629-767-5 | - |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 29/08/2011 |
Details | |
N-[(3-methyl-1H-pyrazol-1-yl)methyl]acetamide; N-[(5-methyl-1H-pyrazol-1-yl)methyl]acetamide | 700-208-8 | - | Sub-chronic toxicity (90-day): oral | 04/10/2018 | 19/11/2018 | Details | |
N-(dimethylvinylsilyl)-1,1-dimethyl-1-vinylsilylamine | 231-701-1 | 7691-02-3 |
Reproductive toxicity (pre-natal developmental toxicity)
“|| Note: Testing proposed with hexamethyldisilazane (CAS 999-97-3)” Sub-chronic toxicity (90 day): inhalation
“|| Note: Testing proposed with hexamethyldisilazane (CAS 999-97-3)” |
12/12/2014 12/12/2014 |
26/01/2015 26/01/2015 |
Details | |
N-(cyclohexylthio)phthalimide | 241-774-1 | 17796-82-6 |
Bioaccumulation: aquatic / sediment Long-term or reproductive toxicity to birds Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
01/07/2011 01/07/2011 01/07/2011 01/07/2011 17/12/2012 |
15/08/2011 15/08/2011 15/08/2011 15/08/2011 31/01/2013 |
Details | |
N-(C16-C18)alkyl(C16-C18)alkane-1-amine | 629-721-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2011 16/06/2011 16/06/2011 |
01/08/2011 01/08/2011 01/08/2011 |
Details | |
N-(4-amino-9,10-dihydro-3-methoxy-9,10-dioxo-1-anthryl)-4-methylbenzenesulphonamide | 201-369-2 | 81-68-5 | Genetic toxicity in vivo | 20/05/2021 | 05/07/2021 | Details | |
N-(3-aminopropyl)iminodiethanol | 225-642-0 | 4985-85-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
N-(3-aminopropyl)-N`-[3-(C16-18 (evennumbered), C18 unsaturated alkyl amino)propyl]propane-1,3-diamine | 628-862-9 | 1219458-11-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 |
Details | |
N-(3-aminopropyl)-N'-C16-18 (evennumbered), C18 unsaturated alkyl -propane-1,3-diamine | 628-863-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
N-(3-aminopropyl)-N'-C16-18 (evennumbered), C18 unsaturated alkyl -propane-1,3-diamine | 628-863-4 | 1219458-14-6 | Reproductive toxicity (pre-natal developmental toxicity) | 24/01/2019 | 11/03/2019 | Details | |
N-(3-(trimethoxysilyl)propyl)ethylenediamine | 217-164-6 | 1760-24-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
N-(2-nitrophenyl)phosphoric triamide | 477-690-9 | - | Long-term toxicity to fish | 18/03/2021 | 03/05/2021 | Details | |
N-(2-hydroxypropyl)oleamide | 203-828-2 | 111-05-7 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 28/09/2014 |
Details | |
N-(2-hydroxyethyl)-N-[2-[(1-oxooctyl)amino]ethyl]-β-alanine | 264-761-2 | 64265-45-8 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Amphoacetates C8-C18 (EC 931-291-0) || Note: Testing proposal is based on concern identified by the registrant | 21/01/2021 | 08/03/2021 | Details | |
N-(2-hydroxyethyl)-N-[2-[(1-oxooctyl)amino]ethyl]-β-alanine | 264-761-2 | 64265-45-8 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Amphoacetates C8-C18 (EC 931-291-0) || Note: Testing proposal is based on concern identified by the registrant. | 25/05/2020 | 09/07/2020 | Details | |
N-(2-ethylhexyl)isononan-1-amide | 810-288-7 | 1700656-13-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
N-(2-(4-amino-N-ethyl-m-toluidino)ethyl)methanesulphonamide sesquisulphate | 247-161-5 | 25646-71-3 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
N-(2,3-dihydro-2-oxo-1H-benzimidazol-5-yl)-3-hydroxy-4-[[2-methoxy-5-[(phenylamino)carbonyl]phenyl]azo]naphthalene-2-carboxamide | 235-425-2 | 12225-06-8 |
7.5.2 Repeated dose toxicity: inhalation 7.8.2 Developmental toxicity / teratogenicity |
08/03/2024 08/03/2024 |
22/04/2024 22/04/2024 |
Details | |
N-(1,1-dimethyl-3-oxobutyl)acrylamide | 220-713-2 | 2873-97-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
N,N’-di[3-(p-toluene sulfonyl)oxy]phenyl urea | 876-151-9 | 2292123-68-1 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 |
Details | |
N,N-dimethyldecan-1-amide | 238-405-1 | 14433-76-2 | Long-term toxicity to fish | 15/07/2011 | 29/08/2011 | Details | |
N,N-dimethyl-N'-(2,2,6,6-tetramethylpiperidin-4-yl)propane-1,3-diamine | 278-817-9 | 78014-16-1 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/08/2021 26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 11/10/2021 |
Details | |
N,N-dimethyl-alkyl-1-amines, reaction products with alkali hydroxide and chloroacetic acid | 939-682-8 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
N,N-bis[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine | 251-459-0 | 33329-35-0 | Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with structurally-related compound | 29/04/2014 | 13/06/2014 | Details | |
N,N-bis(2-ethylhexyl)-5-methyl-1H-benzotriazole-1-methylamine, N,N-bis(2-ethylhexyl)-4-methyl-1H-benzotriazole-1-methylamine, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-4-methyl-, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-5-methyl-, 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-6-methyl-(Mixture) | 939-700-4 | - | Sub-chronic toxicity (90-day): oral | 21/10/2019 | 05/12/2019 | Details | |
N,N,N`,N`,N``-Pentamethyl-N-C16-18 (even numbered) C18 unsat.-alkyl-1,3-propanediammonium chloride | 629-716-7 | 1211950-04-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 |
Details | |
N,N,N',N'-tetramethylhexamethylenediamine | 203-842-9 | 111-18-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) | 221-220-5 | 3033-62-3 |
7.8.1 Toxicity to reproduction 7.8.2 Developmental toxicity / teratogenicity |
08/03/2024 08/03/2024 |
22/04/2024 22/04/2024 |
Details | |
N,N,N',N'-tetrakis(2,3-epoxypropyl)-m-xylene-α,α'-diamine | 264-438-6 | 63738-22-7 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 27/01/2020 | 12/03/2020 | Details | |
N,N,2,8-tetramethyl-5,11-dioxa-2,8-diazatridecan-13-amine | 695-748-3 | 65286-55-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
24/02/2020 24/02/2020 |
09/04/2020 09/04/2020 |
Details | |
N,N'-hexane-1,6-diylbis(hexahydro-2-oxo-1H-azepine-1-carboxamide) | 227-563-7 | 5888-87-9 | Genetic toxicity in vivo | 18/09/2014 | 03/11/2014 | Details | |
N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) | 204-613-6 | 123-26-2 |
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with: “Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine”, CAS 100545-48-0 Sub-chronic toxicity (90 day): oral |
30/09/2015 30/09/2015 30/09/2015 |
16/11/2015 16/11/2015 16/11/2015 |
Details | |
N,N'-diphenyl-p-phenylenediamine | 200-806-4 | 74-31-7 |
Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant. |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
N,N'-dimethyldiphenylthiuram disulphide | 234-196-6 | 10591-84-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2019 16/08/2019 |
30/09/2019 30/09/2019 |
Details | |
N,N'-bis(3-aminopropyl)ethylenediamine | 234-147-9 | 10563-26-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/03/2021 18/03/2021 |
03/05/2021 03/05/2021 |
Details | |
N,N'-bis(2,2,6,6-tetramethyl-4-piperidyl)isophthalamide | 419-710-0 | - |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
12/12/2014 12/12/2014 12/12/2014 |
26/01/2015 26/01/2015 26/01/2015 |
Details | |
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide] | 258-981-8 | 54112-23-1 |
Long-term toxicity to fish Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. |
31/08/2015 | 15/10/2015 | Details | |
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide] | 258-981-8 | 54112-23-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
12/12/2014 12/12/2014 |
26/01/2015 26/01/2015 |
Details | |
N,N''-propane-1,3-diylbis[N'-octadecylurea | 252-667-4 | 35674-65-8 | Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) | 29/03/2016 | 13/05/2016 | Details | |
N,N''-(4-methyl-m-phenylene)bis[N',N'-dimethylurea] | 241-523-6 | 17526-94-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
23/03/2020 23/03/2020 |
07/05/2020 07/05/2020 |
Details | |
N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine | 229-761-9 | 6711-48-4 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with N,N-diethylpropane-1,3-diamine (EC no. 203-236-4) | 22/09/2022 | 07/11/2022 | Details | |
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide | 435-860-1 | 214417-91-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide | 435-860-1 | 214417-91-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2012 17/04/2012 |
01/06/2012 01/06/2012 |
Details | |
Multi-Wall Carbon Nanotubes, synthetic graphite in tubular shape | 231-955-3 | 7782-42-5 | Long-term toxicity to fish | 03/11/2011 | 19/12/2011 | Details | |
Morpholine, 4-C12-14-alkyl derivs. | 800-906-3 | 1402434-48-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Mono- and/or di- and/or tri(1-phenylethyl)-m-cresol and p-cresol | 700-427-9 | - |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
01/12/2010 01/12/2010 01/12/2010 |
17/01/2011 17/01/2011 17/01/2011 |
Details | |
Middle distillate from refinery proces cofeeding vegetable oil | 938-793-9 | - | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2013 | 18/10/2013 | Details | |
methylsilanetriyl triacetate | 224-221-9 | 4253-34-3 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [Trimethoxy(methyl)silane] (EC 214-685-0) | 16/03/2015 | 30/04/2015 | Details | |
methylsilanetriyl triacetate | 224-221-9 | 4253-34-3 | Sub-chronic toxicity (90-day): oral||Note: testing proposed with [triethoxy(methyl)silane] (CAS no. 2031-67-6) | 03/10/2023 | 17/11/2023 | Details | |
Methylphosphonic acid | 213-607-2 | 993-13-5 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4) |
27/05/2019 27/05/2019 |
11/07/2019 11/07/2019 |
Details | |
Methylene-bis-4,1-(N-phenylene-N'-butylurea) | 416-600-4 | - | Bioaccumulation aquatic / sediment | 17/05/2016 | 01/07/2016 | Details | |
Methylamine | 200-820-0 | 74-89-5 | Genetic toxicity in vivo | 14/02/2011 | 31/03/2011 | Details | |
methyl-1h-benzotriazole | 249-596-6 | 29385-43-1 | Sub-chronic toxicity (90-day): oral | 16/12/2020 | 01/02/2021 | Details | |
methyl-1h-benzotriazole | 249-596-6 | 29385-43-1 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate | 16/12/2016 | 30/01/2017 | Details | |
Methyl trimethyl-3-[(1-oxododecyl)amino]propylammonium sulphate | 234-204-8 | 10595-49-0 | Reproductive toxicity (pre-natal developmental toxicity) | 16/12/2020 | 01/02/2021 | Details | |
Methyl isothiocyanate | 209-132-5 | 556-61-6 | Genetic toxicity in vivo | 17/11/2011 | 02/01/2012 | Details | |
Methyl benzoylformate | 239-263-3 | 15206-55-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
Methyl benzoate | 202-259-7 | 93-58-3 | 6.1.2 Long-term toxicity to fish | 08/03/2024 | 22/04/2024 | Details | |
methyl acrylate; methyl propenoate | 202-500-6 | 96-33-3 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
Methyl [3-(trimethoxysilyl)propyl]carbamate | 245-659-7 | 23432-62-4 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/03/2017 10/03/2017 10/03/2017 |
25/04/2017 25/04/2017 25/04/2017 |
Details | |
Methyl 4-[[(2,5-dichlorophenyl)amino]carbonyl]-2-[[2-hydroxy-3-[[(2-methoxyphenyl)amino]carbonyl]-1-naphthyl]azo]benzoate – bulk and nano forms | 263-272-1 | 61847-48-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/10/2023 | 17/11/2023 | Details | |
Methanal, reaction products with 1,3-bis(aminomethyl)benzene and hydroxybenzen | 701-207-5 | 1950616-36-0 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/05/2018 21/05/2018 21/05/2018 |
05/07/2018 05/07/2018 05/07/2018 |
Details | |
Mercaptoacetic acid | 200-677-4 | 68-11-1 | Long-term toxicity to fish | 31/01/2023 | 17/03/2023 | Details | |
Mequinol | 205-769-8 | 150-76-5 | Reproductive toxicity (pre-natal developmental toxicity) | 29/04/2011 | 14/06/2011 | Details | |
Menthol | 201-939-0 | 89-78-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/09/2017 | 16/10/2017 | Details | |
Melamine | 203-615-4 | 108-78-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 17/05/2016 | 01/07/2016 | Details | |
Manganese dioxide | 215-202-6 | 1313-13-9 | Genetic toxicity in vivo | 23/11/2020 | 07/01/2021 | Details | |
Manganese carbonate | 209-942-9 | 598-62-9 | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
Maleic acid | 203-742-5 | 110-16-7 | Reproductive toxicity (pre-natal developmental toxicity) | 17/06/2020 | 03/08/2020 | Details | |
Magnesium, bis(2-hydroxybenzoato-O1,O2)-, ar,ar'-di-C14-18alkyl derivs | 931-371-5 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
Magnesium metaborate | 237-235-5 | 13703-82-7 | Reproductive toxicity (pre-natal developmental toxicity) | 25/11/2021 | 10/01/2022 | Details | |
m-xylene | 203-576-3 | 108-38-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with p-xylene (EC 203-396-5) | 18/02/2021 | 05/04/2021 | Details | |
m-phenylene di(acetate) | 203-596-2 | 108-58-7 | Genetic toxicity in vivo | 27/01/2020 | 12/03/2020 | Details | |
m-cresol | 203-577-9 | 108-39-4 | Long-term toxicity to fish|| Note: testing proposed with p-cresol (EC no. 203-398-6) | 10/05/2022 | 27/06/2022 | Details | |
m-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline | 275-662-9 | 71604-74-5 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 29/08/2014 |
Details | |
Lithium tetrafluoroborate, anhydrous | 238-178-9 | 14283-07-9 | Genetic toxicity in vivo | 25/05/2020 | 09/07/2020 | Details | |
Lithium phosphorodifluoridate | 643-080-8 | 24389-25-1 | Reproductive toxicity (pre-natal developmental toxicity) | 25/05/2020 | 09/07/2020 | Details | |
Lithium hydroxide | 215-183-4 | 1310-65-2 | Reproductive toxicity (two-generation reproductive toxicity) | 29/04/2011 | 14/06/2011 | Details | |
Lithium chloride | 231-212-3 | 7447-41-8 | Reproductive toxicity (two-generation reproductive toxicity) | 29/04/2011 | 14/06/2011 | Details | |
Lithium chloride | 231-212-3 | 7447-41-8 | Genetic toxicity in vivo | 03/11/2023 | 18/12/2023 | Details | |
Lithium carbonate | 209-062-5 | 554-13-2 | Reproductive toxicity (two-generation reproductive toxicity) | 29/04/2011 | 14/06/2011 | Details | |
Lithium bis(oxalato)borate | 456-990-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/05/2019 27/05/2019 |
11/07/2019 11/07/2019 |
Details | |
Lithium bis(fluorosulfonyl)imide | 686-526-7 | 171611-11-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/10/2021 21/10/2021 21/10/2021 |
07/12/2021 07/12/2021 07/12/2021 |
Details | |
Linseed oil, polymerized | 614-114-9 | 67746-08-1 | Reproductive toxicity (pre-natal developmental toxicity) | 18/09/2014 | 03/11/2014 | Details | |
Linseed oil, oxidized | 272-038-8 | 68649-95-6 | Genetic toxicity in vivo | 26/08/2021 | 11/10/2021 | Details | |
Linseed oil, oxidized | 272-038-8 | 68649-95-6 | Genetic toxicity in vivo | 01/07/2011 | 15/08/2011 | Details | |
Linalyl acetate | 204-116-4 | 115-95-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 17/06/2020 | 03/08/2020 | Details | |
Linalool | 201-134-4 | 78-70-6 | Reproductive toxicity (pre-natal developmental toxicity) | 01/07/2021 | 16/08/2021 | Details | |
LiFePO4 | 476-700-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 22/10/2013 | 05/12/2013 | Details | |
l-Glutamic acid, N-coco acyl derivs., disodium salts | 269-085-1 | 68187-30-4 | Sub-chronic toxicity (90-day): oral | 22/09/2022 | 07/11/2022 | Details | |
l-Glutamic acid, N-coco acyl derivs., disodium salts | 269-085-1 | 68187-30-4 | Reproductive toxicity (pre-natal developmental toxicity) | 18/09/2014 | 03/11/2014 | Details | |
Kieselguhr, soda ash flux-calcined | 272-489-0 | 68855-54-9 | Sub-chronic toxicity (90 day): inhalation | 01/07/2011 | 15/08/2011 | Details | |
Itaconic acid | 202-599-6 | - | Reproductive toxicity (two-generation reproductive toxicity) | 16/01/2012 | 01/03/2012 | Details | |
Isotridecan-1-ol | 248-469-2 | 27458-92-0 | Reproductive toxicity (pre-natal developmental toxicity) | 20/12/2017 | 05/02/2018 | Details | |
Isotridecan-1-ol | 248-469-2 | 27458-92-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 16/12/2020 | 01/02/2021 | Details | |
Isopropylcyclohexane | 211-792-4 | 696-29-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Isooctyl acrylate | 249-707-8 | 29590-42-9 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/03/2011 15/03/2011 |
29/04/2011 29/04/2011 |
Details | |
Isononyl isononanoate | 609-993-0 | 42131-25-9 | Sub-chronic toxicity (90-day): oral | 18/09/2014 | 03/11/2014 | Details | |
Isononanoic acid, C16-18 (even numbered)-alkyl esters | 601-141-6 | 111937-03-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 18/06/2018 | 02/08/2018 | Details | |
Isononanoic acid, C16-18 (even numbered)-alkyl esters | 601-141-6 | 111937-03-2 | Sub-chronic toxicity (90-day): oral | 18/09/2014 | 03/11/2014 | Details | |
Isononanoic acid, C16-18 (even numbered)-alkyl esters | 601-141-6 | 111937-03-2 | Long-term toxicity to fish | 01/04/2022 | 16/05/2022 | Details | |
Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane | 224-506-8 | 4390-04-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
Isodecyl methacrylate | 249-978-2 | 29964-84-9 |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
03/10/2023 03/10/2023 |
17/11/2023 17/11/2023 |
Details | |
Isodecyl diphenyl phosphate | 249-828-6 | 29761-21-5 | Bioaccumulation aquatic / sediment | 15/07/2011 | 29/08/2011 | Details | |
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol | 246-771-9 | 25265-77-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/04/2019 26/04/2019 26/04/2019 |
10/06/2019 10/06/2019 10/06/2019 |
Details | |
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol | 246-771-9 | 25265-77-4 | Reproductive toxicity (pre-natal developmental toxicity) | 16/06/2011 | 01/08/2011 | Details | |
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol | 246-771-9 | 25265-77-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/09/2022 | 07/11/2022 | Details | |
isliFe | - | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 17/12/2019 | 31/01/2020 | Details | |
Iron, complexes with diazotized 5-amino-2-(phenylamino)benzenesulfonic acid monosodium salt coupled with 4-[(2-hydroxy-3,5-dinitrophenyl)azo]-1,3-benzenediol, diazotized 4-nitrobenzenamine and diazotized 3-aminobenzenesulfonic acid monosodium salt | 276-464-5 | 72207-77-3 | Genetic toxicity in vivo || Note: testing proposed with Acid Brown 360 (EC 946-788-8) | 20/05/2021 | 05/07/2021 | Details | |
inorganic phosphorus salt | 428-310-5 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
Inorganic phosphorus salt | 428-310-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 01/07/2021 | 16/08/2021 | Details | |
Imidazolium compounds, 2-C17-unsatd.-alkyl-1-(2-C18-unsatd. amidoethyl)-4,5-dihydro-N-methyl, Me sulfates | 931-745-8 | - | Sub-chronic toxicity (90-day): oral | 01/07/2011 | 15/08/2011 | Details | |
Imidazolidine-2-thione | 202-506-9 | 96-45-7 | Long-term toxicity to fish | 29/04/2011 | 14/06/2011 | Details | |
Icosane | 204-018-1 | 112-95-8 | Reproductive toxicity (two-generation reproductive toxicity)// Note: Testing proposed with Hydrocarbon, C9-C12, normal, isoalkane, cyclics, 2-25% aromatics; Hydrocarbon, C16-C20, normal, isoalkane cyclics, 2-30% aromatics | 02/07/2013 | 16/08/2013 | Details | |
Icos-1-ene | 222-374-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 |
Details | |
Hydroxyethylated 2-butyne-1,4-diol | 608-711-3 | 32167-31-0 | Sub-chronic toxicity (90-day): oral | 17/06/2014 | 01/08/2014 | Details | |
Hydroxycyclohexyl phenyl ketone | 213-426-9 | 947-19-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 17/09/2019 | 01/11/2019 | Details | |
Hydroxyacetone | 204-124-8 | 116-09-6 | Genetic toxicity in vivo | 23/11/2020 | 07/01/2021 | Details | |
Hydrogenated oligomerisation product, including dimers and trimers, of tetradec-1-ene and alkene | - | - |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
10/08/2009 10/08/2009 |
24/09/2009 24/09/2009 |
Details | |
Hydrogen [4-[[4-(diethylamino)phenyl][4-[ethyl[(3-sulphonatobenzyl)amino]-o-tolyl]methylene]-3-methylcyclohexa-2,5-dien-1-ylidene](ethyl)(3-sulphonatobenzyl)ammonium, sodium salt | 229-390-2 | 6505-30-2 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 23/11/2020 | 07/01/2021 | Details | |
Hydrochloric acid, reaction products with aniline and nitrobenzene, sulfonated, sodium salts | 291-454-0 | 90411-76-0 | Reproductive toxicity (pre-natal developmental toxicity) | 30/11/2015 | 14/01/2016 | Details | |
Hydrocarbons, C9-unsaturated, polymerized | 615-276-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 |
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Hydrocarbons, C9-C12, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) | 919-446-0 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, <2% aromatics | 919-857-5 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C9-C11, isoalkanes, cyclics, <2% aromatics | 920-134-1 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |