Predchádzajúce/výsledok
Predchádzajúce/výsledok
Predchádzajúce/výsledok
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate | 413-750-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 30/09/2021 | 15/11/2021 | Details | |
2-methyl-1,3-propanediol | 412-350-5 | 2163-42-0 | Long-term toxicity to fish | 15/01/2024 | 29/02/2024 | Details | |
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol | 412-300-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 18/02/2021 | 05/04/2021 | Details | |
1-acetyl-4-(3-dodecyl-2,5-dioxo-1-pyrrolidinyl)-2,2,6,6-tetramethylpiperidine | 411-930-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 |
Details | |
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate | 411-700-4 | 140921-24-0 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/05/2022 10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 27/06/2022 |
Details | |
Reaction mass of 2,5-bis(isocyanatomethyl)-bicyclo[2.2.1]heptane and 2,6-bis(isocyanatomethyl)-bicyclo[2.2.1]heptane | 411-280-2 | - | Genetic toxicity in vivo | 16/07/2012 | 30/08/2012 | Details | |
2,4-dimethyl-6-(1-methyl-pentadecyl)phenol | 411-220-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 25/09/2012 | 12/11/2012 | Details | |
A mixture of: tetrasodium-phosphonoethane-1,2-dicarboxylate,hexasodium-phosphonobutane-1,2,3,4-tetracarboxylate | 410-800-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/03/2012 06/03/2012 |
20/04/2012 20/04/2012 |
Details | |
Reaction products of 2-(4,6-bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl)-5-hydroxy phenol with ((C10-16, rich in C12-13 alkyloxy)methyl)oxyrane | 410-560-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/01/2012 16/01/2012 |
01/03/2012 01/03/2012 |
Details | |
Bis(4-methylbenzoyl)peroxide | 407-950-9 | 895-85-2 | 6.1.2 Long-term toxicity to fish||Note: testing proposed with p-toluic acid (EC no. 202-803-3) or with bis(4-methylbenzoyl) peroxide (EC no. 407-905-9) | 08/03/2024 | 22/04/2024 | Details | |
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) | 407-560-9 | 107934-68-9 | Bioaccumulation aquatic / sediment || Note: Testing proposal is based on concern identified by the registrant. | 16/10/2014 | 01/12/2014 | Details | |
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) | 407-560-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/06/2020 17/06/2020 |
03/08/2020 03/08/2020 |
Details | |
Reaction mass of bis(2,2,6,6-tetramethyl-1-octyloxypiperidin-4-yl)-1,10-decanedioate and 1,8-bis[(2,2,6,6-tetramethyl-4-((2,2,6,6-tetramethyl-1-octyloxypiperidin-4-yl)-decan-1,10-dioyl)piperidin-1-yl)oxy]octane | 406-750-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
04/06/2012 04/06/2012 |
19/07/2012 19/07/2012 |
Details | |
4-(4-isopropoxyphenylsulfonyl)phenol | 405-520-5 | 95235-30-6 | Reproductive toxicity (pre-natal developmental toxicity) | 24/08/2020 | 08/10/2020 | Details | |
A mixture of: cis-tetrahydro-2-isobutyl-4-methylpyran-4-ol; trans-tetrahydro-2-isobutyl-4-methylpyran-4-ol | 405-040-6 | 63500-71-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/06/2015 | 10/08/2015 | Details | |
a mixture of: cistetrahydro-2-isobutyl-4-methylpyran-4-ol,transtetrahydro-2-isobutyl-4-methylpyran-4-ol | 405-040-6 | 63500-71-0 |
(90-day): oral Reproductive toxicity (developmental toxicity) Sub-chronic toxicity |
20/10/2010 20/10/2010 20/10/2010 |
06/12/2010 06/12/2010 06/12/2010 |
Details | |
Dicyclopentyldimethoxysilane | 404-370-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2011 16/12/2011 16/12/2011 |
30/01/2012 30/01/2012 30/01/2012 |
Details | |
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone | 404-360-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 24/05/2013 | 08/07/2013 | Details | |
Tetrakis(phenylmethyl)thioperoxydi(carbothioamide) | 404-310-0 | 10591-85-2 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/09/2021 30/09/2021 30/09/2021 |
15/11/2021 15/11/2021 15/11/2021 |
Details | |
2-ethoxyethyl-2-(4-(2,6-dihydro-2,6-dioxo-7-phenyl-1,5-dioxaindacen-3-yl)phenoxy)acetate | 403-960-2 | - | Genetic toxicity in vivo | 03/10/2023 | 17/11/2023 | Details | |
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one | 403-830-5 | 89331-94-2 | Bioaccumulation aquatic / sediment | 12/06/2015 | 27/07/2015 | Details | |
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one | 403-830-5 | 89331-94-2 | Sub-chronic toxicity (90-day): oral | 26/03/2018 | 11/05/2018 | Details | |
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one | 403-830-5 | 89331-94-2 | Sub-chronic toxicity (90-day): oral | 02/09/2013 | 18/10/2013 | Details | |
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one | 403-830-5 | 89331-94-2 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
23/04/2018 23/04/2018 23/04/2018 |
07/06/2018 07/06/2018 07/06/2018 |
Details | |
Calcium 4-chloro-2-(5-hydroxy-3-methyl-1-(3-sulfonatophenyl)pyrazol-4-ylazo)-5-methylbenzenesulfonate | 403-530-4 | 129423-54-7 | 7.8.2 Developmental toxicity / teratogenicity | 08/03/2024 | 22/04/2024 | Details | |
A mixture of: bis[4-diphenylsulfoniumphenyl]sulfide-bishexafluoroantimonate; thiophenoxyphenylsulfonium hexafluoroantimonate | 403-500-0 | 159120-95-3 | Genetic toxicity in vivo | 03/10/2023 | 17/11/2023 | Details | |
O,O-di(1-methylethyl)trithio-bis-thioformate,O,O-di(1-methylethyl)tetrathio-bis-thioformate,O,O-di(1-methylethyl)pentathio-bis-thioformate | 403-030-6 | - | Reproductive toxicity (pre-natal developmental toxicity) | 24/05/2013 | 08/07/2013 | Details | |
pentasodium 5-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}-3-[2-(1,5-disulfonaphthalen-2-yl)diazen-1-yl]-4-hydroxynaphthalene-2,7-disulfonate | 402-420-3 | 89157-03-9 | Sub-chronic toxicity (90-day): oral | 25/06/2019 | 09/08/2019 | Details | |
Cyclohexyldimethoxymethylsilane | 402-140-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/01/2012 16/01/2012 16/01/2012 |
01/03/2012 01/03/2012 01/03/2012 |
Details | |
Benzenamine, 4,4'-methylenebis[3-chloro-2,6-diethyl- | 402-130-7 | 106246-33-7 | Reproductive toxicity (pre-natal developmental toxicity) | 01/04/2022 | 16/05/2022 | Details | |
3-(dimethylamino)propylurea | 401-950-2 | 31506-43-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 |
Details | |
A mixture of cis- and trans-cyclohexadec-8-en-1-one | 401-700-2 | 3100-36-5 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 12/01/2023 |
Details | |
Diamminediisocyanatozinc | 401-610-3 | 122012-52-6 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione | 401-540-3 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/03/2018 26/03/2018 26/03/2018 |
11/05/2018 11/05/2018 11/05/2018 |
Details | |
Butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium(trialkyloxy)titanium phosphate | 401-100-0 | - | Sub-chronic toxicity (90-day): oral | 27/05/2019 | 11/07/2019 | Details | |
A mixture of: α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-hydroxypoly(oxyethylene),α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyloxypoly(oxyethylene) | 400-830-7 | - | Reproductive toxicity (pre-natal developmental toxicity) | 16/12/2011 | 30/01/2012 | Details | |
Tris(2,5,8,11-tetraoxatridecyl) orthoborate | 310-290-3 | 161907-80-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
Benzenamine, reaction products with aniline hydrochloride and nitrobenzene, hydrochlorides | 309-913-1 | 101357-16-8 | Sub-chronic toxicity (90-day): oral | 21/09/2020 | 05/11/2020 | Details | |
Tar, brown-coal, low-temp. | 309-886-6 | 101316-84-1 | Sub-chronic toxicity (90-day): oral | 29/07/2011 | 12/09/2011 | Details | |
Residues (petroleum), vacuum distn. residue hydrogenation | 309-713-4 | 100684-40-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
Residues (petroleum), distn. residue hydrogenation | 309-712-9 | 100684-39-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine | 309-629-8 | 100545-48-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
d-Glucose, ether with glycerol | 309-496-6 | 100402-60-6 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs. | 308-760-8 | 98246-87-8 | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
Alkenes, C7-9, hydroformylation products, distn. residues, heavy cracked fraction | 308-482-7 | 98072-31-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 02/11/2018 | 17/12/2018 | Details | |
Alkenes, C7-9, hydroformylation products, distn. residues, heavy cracked fraction | 308-482-7 | 98072-31-2 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
01/08/2011 01/08/2011 |
15/09/2011 15/09/2011 |
Details | |
Ethanol, 2,2'-iminobis-, N-(C13-15-branched and linear alkyl) derivs. | 308-208-6 | 97925-95-6 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
Ethanol, 2,2'-iminobis-, N-(C13-15-branched and linear alkyl) derivs. | 308-208-6 | 97925-95-6 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed on rabbits | 14/08/2014 | 28/09/2014 | Details | |
2-Propanol, 1,1'-[[3-[(3-aminopropyl)amino]propyl]imino]bis-, N-tallow alkyl derivs | 307-276-4 | 97592-79-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
Resin acids and Rosin acids, fumarated, esters with glycerol | 307-051-0 | 97489-11-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6) |
19/07/2013 19/07/2013 |
02/09/2013 02/09/2013 |
Details | |
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene] | 306-832-3 | 97416-84-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/07/2021 01/07/2021 |
16/08/2021 16/08/2021 |
Details | |
Dodecene, branched | 306-479-5 | 97280-83-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7) Sub-chronic toxicity (90-day): oral||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
Soybean oil, epoxidized, Me ester, reaction products with propylene glycol | 306-246-8 | 96690-51-6 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
Amines, C12-14-tert-alkyl, mixed sec-Bu and iso-Bu phosphates | 306-227-4 | 96690-34-5 | Sub-chronic toxicity (90-day): oral || Note: testing proposed with Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates (EC 279-632-6) || Note: Testing proposal is based on concern identified by the registrant. | 23/11/2020 | 07/01/2021 | Details | |
Fatty acids, C8-10, C12-18-alkyl esters | 306-082-7 | 95912-86-0 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/04/2022 01/04/2022 01/04/2022 |
16/05/2022 16/05/2022 16/05/2022 |
Details | |
Hydrocarbons, C4, 1,3-butadiene- and isobutene-free | 306-004-1 | 95465-89-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
Rosin, fumarated, reaction products with formaldehyde | 305-795-0 | 95009-65-7 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0). Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0) |
02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 |
Details | |
Rosin, fumarated, reaction products with formaldehyde | 305-795-0 | 95009-65-7 | Reproductive toxicity (pre-natal developmental toxicity) | 06/03/2012 | 20/04/2012 | Details | |
Resin acids and Rosin acids, maleated, esters with pentaerythritol | 305-516-2 | 94581-17-6 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7) Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6) |
19/07/2013 19/07/2013 |
02/09/2013 02/09/2013 |
Details | |
Resin acids and Rosin acids, fumarated, esters with pentaerythritol | 305-514-1 | 94581-15-4 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7) Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7) Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6) Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6) |
19/07/2013 02/07/2013 02/07/2013 19/07/2013 19/07/2013 02/07/2013 |
02/09/2013 16/08/2013 16/08/2013 02/09/2013 02/09/2013 16/08/2013 |
Details | |
Resin acids and Rosin acids, fumarated, esters with pentaerythritol | 305-514-1 | 94581-15-4 | Reproductive toxicity (pre-natal developmental toxicity) | 16/07/2012 | 30/08/2012 | Details | |
Sodium N-(2-carboxyethyl)-N-(2-ethylhexyl)-β-alaninate | 305-318-6 | 94441-92-6 | Reproductive toxicity (pre-natal developmental toxicity) | 02/06/2014 | 17/07/2014 | Details | |
Saccharomyces cerevisiae, lysate | 305-230-8 | 94350-12-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/09/2021 30/09/2021 |
15/11/2021 15/11/2021 |
Details | |
Trimethyl-3-[(1-oxo-10-undecenyl)amino]propylammonium methyl sulphate | 304-990-8 | 94313-91-4 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Methyl trimethyl-3-[(1-oxododecyl)amino]propylammonium sulphate EC 234-204-8 || Note: Testing proposal is based on concern identified by the registrant | 16/12/2020 | 01/02/2021 | Details | |
Aluminum, benzoate C16-18-fatty acids complexes | 303-385-6 | 94166-87-7 | Reproductive toxicity (pre-natal developmental toxicity) | 25/06/2015 | 10/08/2015 | Details | |
Boric acid (H3BO3), reaction products with ethanolamine | 302-207-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/01/2012 16/01/2012 16/01/2012 |
01/03/2012 01/03/2012 01/03/2012 |
Details | |
(octahydro-4,7-methano-1H-indenyl)methyl acrylate | 300-723-4 | 93962-84-6 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 23/11/2020 | 07/01/2021 | Details | |
3-[[3-[[(2-cyanoethyl)amino]methyl]-3,5,5-trimethylcyclohexyl]amino]propiononitrile | 300-496-1 | 93940-97-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
Silicic acid (H4SiO4), tetraethyl ester, reaction products with bis(acetyloxy)dibutylstannane | 300-344-4 | 93925-42-9 | Genetic toxicity in vivo | 21/01/2021 | 08/03/2021 | Details | |
Gas oils, paraffinic | 300-227-8 | 93924-33-5 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Alkenes, C24-28 α- | 300-203-7 | 93924-11-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
Alkenes, C20-24 α- | 300-202-1 | 93924-10-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
Reaction mass of (E)-3-methyl-5-phenylpent-2-enenitrile and (Z)-3-methyl-5-phenylpent-2-enenitrile | 299-682-2 | 93893-89-1 | Reproductive toxicity (pre-natal developmental toxicity) | 16/12/2020 | 01/02/2021 | Details | |
tripotassium propylsilanetriolate | 299-135-8 | 93857-00-2 |
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7) Sub-chronic toxicity (90 day): inhalation
Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7) |
16/03/2015 16/03/2015 |
30/04/2015 30/04/2015 |
Details | |
Zinc bis[O-(6-methylheptyl)] bis[O-(sec-butyl)] bis(dithiophosphate) | 298-577-9 | 93819-94-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
Alkenes, C15-18 | 297-797-2 | 93762-80-2 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 25/06/2012 |
30/09/2011 30/09/2011 09/08/2012 |
Details | |
Phosphorous acid, tri-C12-14-alkyl esters | 297-701-9 | 93686-48-7 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) |
16/02/2015 16/02/2015 |
02/04/2015 02/04/2015 |
Details | |
Hydrocarbons, C4, 1,3-butadiene-free, polymd., triisobutylene fraction, hydrogenated | 297-629-8 | 93685-81-5 | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C4, 1,3-butadiene-free, polymd., tetraisobutylene fraction, hydrogenated | 297-628-2 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Ashes (residues), plant | 297-049-5 | 93333-79-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2011 16/05/2011 16/05/2011 |
30/06/2011 30/06/2011 30/06/2011 |
Details | |
Ashes (residues), plant | 297-049-5 | 93333-79-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
2-Naphthalenol, 1-[[4-(phenylazo)phenyl]azo]-, ar-heptyl ar',ar''-Me derivs. | 296-120-8 | 92257-31-3 | Genetic toxicity in vivo | 16/12/2020 | 01/02/2021 | Details | |
Rosin, fumarated, reaction products with glycerol and pentaerythritol | 296-047-1 | 92202-14-7 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7) Reproductive toxicity (two-generation reproductive toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4) Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS 94581-15-4) Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6) Sub-chronic toxicity (90-day): oral || Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS 97489-11-7); Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS 94581-15-4); and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS 94581-17-6) |
19/07/2013 19/07/2013 02/07/2013 19/07/2013 02/07/2013 |
02/09/2013 02/09/2013 16/08/2013 02/09/2013 16/08/2013 |
Details | |
Rosin, fumarated, reaction products with glycerol and pentaerythritol | 296-047-1 | 92202-14-7 | Reproductive toxicity (pre-natal developmental toxicity) | 16/07/2012 | 30/08/2012 | Details | |
Resin acids and Rosin acids, reaction products with formaldehyde, potassium salt | 295-855-1 | 92129-53-8 | Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), and Rosin, reaction products with formaldehyde (CAS RN 91081-53-7) | 02/07/2013 | 16/08/2013 | Details | |
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides | 295-714-4 | 92128-22-8 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides | 295-714-4 | 92128-22-8 | Reproductive toxicity (pre-natal developmental toxicity) | 28/02/2018 | 16/04/2018 | Details | |
dihydro-3-(tripropenyl)furan-2,5-dione | 295-556-6 | 92077-08-2 | Reproductive toxicity (pre-natal developmental toxicity) | 30/09/2015 | 16/11/2015 | Details | |
Residues (petroleum), thermal cracked vacuum | 295-518-9 | 92062-05-0 |
Genetic toxicity in vivo||Note: testing proposed with Asphalt (EC no. 232-490-9) Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Asphalt (EC no. 232-490-9) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Asphalt (EC no. 232-490-9) Sub-chronic toxicity (90-day): oral||Note: testing proposed with Asphalt (EC no. 232-490-9) |
04/12/2023 04/12/2023 04/12/2023 04/12/2023 |
18/01/2024 18/01/2024 18/01/2024 18/01/2024 |
Details | |
Residues (petroleum), thermal cracked vacuum | 295-518-9 | 92062-05-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
Residues (petroleum), thermal cracked vacuum | 295-518-9 | 062-05-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Asphalt (CAS 8052-42-4) | 25/06/2019 | 09/08/2019 | Details | |
Gas oils (petroleum), hydrotreated light vacuum | 295-407-5 | 92045-24-4 | Reproductive toxicity (two-generation reproductive toxicity) | 15/07/2011 | 29/08/2011 | Details | |
Hydrocarbons, C4, steam-cracker distillate | 295-405-4 | 92045-23-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1) Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
Extracts (petroleum), deasphalted vacuum residue solvent | 295-332-8 | 91995-70-9 | Reproductive toxicity (two-generation reproductive toxicity) | 29/07/2011 | 12/09/2011 | Details | |
Extracts (petroleum), deasphalted vacuum residue solvent | 295-332-8 | 91995-70-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
Extracts (petroleum), deasphalted vacuum residue solvent | 295-332-8 | 91995-70-9 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Extracts (petroleum), residual oil solvent (EC no. 265-110-5) | 06/06/2023 | 21/07/2023 | Details | |
Cobalt, borate propionate complexes | 295-033-2 | 91782-61-5 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Cobalt, borate 2-ethylhexanoate complexes | 295-032-7 | 91782-60-4 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant |
07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 |
Details | |
Tar, wood | 294-436-0 | 91722-33-7 | Reproductive toxicity (pre-natal developmental toxicity) | 23/02/2022 | 12/04/2022 | Details | |
Resin acids and Rosin acids, maleated, calcium salts | 294-402-5 | 91722-01-9 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0) Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0) |
02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 |
Details | |