Predchádzajúce/výsledok

Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate 413-750-2 - Reproductive toxicity (pre-natal developmental toxicity) 30/09/2021 15/11/2021 Details
2-methyl-1,3-propanediol 412-350-5 2163-42-0 Long-term toxicity to fish 15/01/2024 29/02/2024 Details
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 - Reproductive toxicity (pre-natal developmental toxicity) 18/02/2021 05/04/2021 Details
1-acetyl-4-(3-dodecyl-2,5-dioxo-1-pyrrolidinyl)-2,2,6,6-tetramethylpiperidine 411-930-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
12/01/2023
12/01/2023
Details
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate 411-700-4 140921-24-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/05/2022
10/05/2022
10/05/2022
27/06/2022
27/06/2022
27/06/2022
Details
Reaction mass of 2,5-bis(isocyanatomethyl)-bicyclo[2.2.1]heptane and 2,6-bis(isocyanatomethyl)-bicyclo[2.2.1]heptane 411-280-2 - Genetic toxicity in vivo 16/07/2012 30/08/2012 Details
2,4-dimethyl-6-(1-methyl-pentadecyl)phenol 411-220-5 - Reproductive toxicity (pre-natal developmental toxicity) 25/09/2012 12/11/2012 Details
A mixture of: tetrasodium-phosphonoethane-1,2-dicarboxylate,hexasodium-phosphonobutane-1,2,3,4-tetracarboxylate 410-800-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/03/2012
06/03/2012
20/04/2012
20/04/2012
Details
Reaction products of 2-(4,6-bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl)-5-hydroxy phenol with ((C10-16, rich in C12-13 alkyloxy)methyl)oxyrane 410-560-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/01/2012
16/01/2012
01/03/2012
01/03/2012
Details
Bis(4-methylbenzoyl)peroxide 407-950-9 895-85-2 6.1.2 Long-term toxicity to fish||Note: testing proposed with p-toluic acid  (EC no. 202-803-3) or with bis(4-methylbenzoyl) peroxide (EC no. 407-905-9) 08/03/2024 22/04/2024 Details
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) 407-560-9 107934-68-9 Bioaccumulation aquatic / sediment || Note: Testing proposal is based on concern identified by the registrant. 16/10/2014 01/12/2014 Details
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) 407-560-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2020
17/06/2020
03/08/2020
03/08/2020
Details
Reaction mass of bis(2,2,6,6-tetramethyl-1-octyloxypiperidin-4-yl)-1,10-decanedioate and 1,8-bis[(2,2,6,6-tetramethyl-4-((2,2,6,6-tetramethyl-1-octyloxypiperidin-4-yl)-decan-1,10-dioyl)piperidin-1-yl)oxy]octane 406-750-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
04/06/2012
04/06/2012
19/07/2012
19/07/2012
Details
4-(4-isopropoxyphenylsulfonyl)phenol 405-520-5 95235-30-6 Reproductive toxicity (pre-natal developmental toxicity) 24/08/2020 08/10/2020 Details
A mixture of: cis-tetrahydro-2-isobutyl-4-methylpyran-4-ol; trans-tetrahydro-2-isobutyl-4-methylpyran-4-ol 405-040-6 63500-71-0 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2015 10/08/2015 Details
a mixture of: cistetrahydro-2-isobutyl-4-methylpyran-4-ol,transtetrahydro-2-isobutyl-4-methylpyran-4-ol 405-040-6 63500-71-0
(90-day): oral
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity
20/10/2010
20/10/2010
20/10/2010
06/12/2010
06/12/2010
06/12/2010
Details
Dicyclopentyldimethoxysilane 404-370-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2011
16/12/2011
16/12/2011
30/01/2012
30/01/2012
30/01/2012
Details
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone 404-360-3 - Reproductive toxicity (pre-natal developmental toxicity) 24/05/2013 08/07/2013 Details
Tetrakis(phenylmethyl)thioperoxydi(carbothioamide) 404-310-0 10591-85-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/09/2021
30/09/2021
30/09/2021
15/11/2021
15/11/2021
15/11/2021
Details
2-ethoxyethyl-2-(4-(2,6-dihydro-2,6-dioxo-7-phenyl-1,5-dioxaindacen-3-yl)phenoxy)acetate 403-960-2 - Genetic toxicity in vivo 03/10/2023 17/11/2023 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Bioaccumulation aquatic / sediment 12/06/2015 27/07/2015 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Sub-chronic toxicity (90-day): oral 26/03/2018 11/05/2018 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Sub-chronic toxicity (90-day): oral 02/09/2013 18/10/2013 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
23/04/2018
23/04/2018
23/04/2018
07/06/2018
07/06/2018
07/06/2018
Details
Calcium 4-chloro-2-(5-hydroxy-3-methyl-1-(3-sulfonatophenyl)pyrazol-4-ylazo)-5-methylbenzenesulfonate 403-530-4 129423-54-7 7.8.2 Developmental toxicity / teratogenicity 08/03/2024 22/04/2024 Details
A mixture of: bis[4-diphenylsulfoniumphenyl]sulfide-bishexafluoroantimonate; thiophenoxyphenylsulfonium hexafluoroantimonate 403-500-0 159120-95-3 Genetic toxicity in vivo 03/10/2023 17/11/2023 Details
O,O-di(1-methylethyl)trithio-bis-thioformate,O,O-di(1-methylethyl)tetrathio-bis-thioformate,O,O-di(1-methylethyl)pentathio-bis-thioformate 403-030-6 - Reproductive toxicity (pre-natal developmental toxicity) 24/05/2013 08/07/2013 Details
pentasodium 5-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}-3-[2-(1,5-disulfonaphthalen-2-yl)diazen-1-yl]-4-hydroxynaphthalene-2,7-disulfonate 402-420-3 89157-03-9 Sub-chronic toxicity (90-day): oral 25/06/2019 09/08/2019 Details
Cyclohexyldimethoxymethylsilane 402-140-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/01/2012
16/01/2012
16/01/2012
01/03/2012
01/03/2012
01/03/2012
Details
Benzenamine, 4,4'-methylenebis[3-chloro-2,6-diethyl- 402-130-7 106246-33-7 Reproductive toxicity (pre-natal developmental toxicity) 01/04/2022 16/05/2022 Details
3-(dimethylamino)propylurea 401-950-2 31506-43-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/06/2023
06/06/2023
21/07/2023
21/07/2023
Details
A mixture of cis- and trans-cyclohexadec-8-en-1-one 401-700-2 3100-36-5
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
28/11/2022
12/01/2023
12/01/2023
12/01/2023
Details
Diamminediisocyanatozinc 401-610-3 122012-52-6
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione 401-540-3 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/03/2018
26/03/2018
26/03/2018
11/05/2018
11/05/2018
11/05/2018
Details
Butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium(trialkyloxy)titanium phosphate 401-100-0 - Sub-chronic toxicity (90-day): oral 27/05/2019 11/07/2019 Details
A mixture of: α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-hydroxypoly(oxyethylene),α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyloxypoly(oxyethylene) 400-830-7 - Reproductive toxicity (pre-natal developmental toxicity) 16/12/2011 30/01/2012 Details
Tris(2,5,8,11-tetraoxatridecyl) orthoborate 310-290-3 161907-80-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Details
Benzenamine, reaction products with aniline hydrochloride and nitrobenzene, hydrochlorides 309-913-1 101357-16-8 Sub-chronic toxicity (90-day): oral 21/09/2020 05/11/2020 Details
Tar, brown-coal, low-temp. 309-886-6 101316-84-1 Sub-chronic toxicity (90-day): oral 29/07/2011 12/09/2011 Details
Residues (petroleum), vacuum distn. residue hydrogenation 309-713-4 100684-40-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Details
Residues (petroleum), distn. residue hydrogenation 309-712-9 100684-39-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Details
Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine 309-629-8 100545-48-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Details
d-Glucose, ether with glycerol 309-496-6 100402-60-6 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014 Details
2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs. 308-760-8 98246-87-8 Long-term toxicity to fish 22/09/2022 07/11/2022 Details
Alkenes, C7-9, hydroformylation products, distn. residues, heavy cracked fraction 308-482-7 98072-31-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 02/11/2018 17/12/2018 Details
Alkenes, C7-9, hydroformylation products, distn. residues, heavy cracked fraction 308-482-7 98072-31-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
01/08/2011
01/08/2011
15/09/2011
15/09/2011
Details
Ethanol, 2,2'-iminobis-, N-(C13-15-branched and linear alkyl) derivs. 308-208-6 97925-95-6
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Details
Ethanol, 2,2'-iminobis-, N-(C13-15-branched and linear alkyl) derivs. 308-208-6 97925-95-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed on rabbits 14/08/2014 28/09/2014 Details
2-Propanol, 1,1'-[[3-[(3-aminopropyl)amino]propyl]imino]bis-, N-tallow alkyl derivs 307-276-4 97592-79-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Details
Resin acids and Rosin acids, fumarated, esters with glycerol 307-051-0 97489-11-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)
19/07/2013
19/07/2013
02/09/2013
02/09/2013
Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene] 306-832-3 97416-84-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/07/2021
01/07/2021
16/08/2021
16/08/2021
Details
Dodecene, branched 306-479-5 97280-83-6
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7)
Sub-chronic toxicity (90-day): oral||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
Soybean oil, epoxidized, Me ester, reaction products with propylene glycol 306-246-8 96690-51-6 Genetic toxicity in vivo 18/03/2021 03/05/2021 Details
Amines, C12-14-tert-alkyl, mixed sec-Bu and iso-Bu phosphates 306-227-4 96690-34-5 Sub-chronic toxicity (90-day): oral || Note: testing proposed with Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates (EC 279-632-6) || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021 Details
Fatty acids, C8-10, C12-18-alkyl esters 306-082-7 95912-86-0
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/04/2022
01/04/2022
01/04/2022
16/05/2022
16/05/2022
16/05/2022
Details
Hydrocarbons, C4, 1,3-butadiene- and isobutene-free 306-004-1 95465-89-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
Rosin, fumarated, reaction products with formaldehyde 305-795-0 95009-65-7
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0).
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)
02/07/2013
02/07/2013
16/08/2013
16/08/2013
Details
Rosin, fumarated, reaction products with formaldehyde 305-795-0 95009-65-7 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, maleated, esters with pentaerythritol 305-516-2 94581-17-6
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7)
Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)
19/07/2013
19/07/2013
02/09/2013
02/09/2013
Details
Resin acids and Rosin acids, fumarated, esters with pentaerythritol 305-514-1 94581-15-4
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7)
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7)
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)
19/07/2013
02/07/2013
02/07/2013
19/07/2013
19/07/2013
02/07/2013
02/09/2013
16/08/2013
16/08/2013
02/09/2013
02/09/2013
16/08/2013
Details
Resin acids and Rosin acids, fumarated, esters with pentaerythritol 305-514-1 94581-15-4 Reproductive toxicity (pre-natal developmental toxicity) 16/07/2012 30/08/2012 Details
Sodium N-(2-carboxyethyl)-N-(2-ethylhexyl)-β-alaninate 305-318-6 94441-92-6 Reproductive toxicity (pre-natal developmental toxicity) 02/06/2014 17/07/2014 Details
Saccharomyces cerevisiae, lysate 305-230-8 94350-12-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/09/2021
30/09/2021
15/11/2021
15/11/2021
Details
Trimethyl-3-[(1-oxo-10-undecenyl)amino]propylammonium methyl sulphate 304-990-8 94313-91-4 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Methyl trimethyl-3-[(1-oxododecyl)amino]propylammonium sulphate EC 234-204-8 || Note: Testing proposal is based on concern identified by the registrant 16/12/2020 01/02/2021 Details
Aluminum, benzoate C16-18-fatty acids complexes 303-385-6 94166-87-7 Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015 Details
Boric acid (H3BO3), reaction products with ethanolamine 302-207-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/01/2012
16/01/2012
16/01/2012
01/03/2012
01/03/2012
01/03/2012
Details
(octahydro-4,7-methano-1H-indenyl)methyl acrylate 300-723-4 93962-84-6 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021 Details
3-[[3-[[(2-cyanoethyl)amino]methyl]-3,5,5-trimethylcyclohexyl]amino]propiononitrile 300-496-1 93940-97-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
Silicic acid (H4SiO4), tetraethyl ester, reaction products with bis(acetyloxy)dibutylstannane 300-344-4 93925-42-9 Genetic toxicity in vivo 21/01/2021 08/03/2021 Details
Gas oils, paraffinic 300-227-8 93924-33-5 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Alkenes, C24-28 α- 300-203-7 93924-11-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Details
Alkenes, C20-24 α- 300-202-1 93924-10-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Details
Reaction mass of (E)-3-methyl-5-phenylpent-2-enenitrile and (Z)-3-methyl-5-phenylpent-2-enenitrile 299-682-2 93893-89-1 Reproductive toxicity (pre-natal developmental toxicity) 16/12/2020 01/02/2021 Details
tripotassium propylsilanetriolate 299-135-8 93857-00-2
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7)
Sub-chronic toxicity (90 day): inhalation Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7)
16/03/2015
16/03/2015
30/04/2015
30/04/2015
Details
Zinc bis[O-(6-methylheptyl)] bis[O-(sec-butyl)] bis(dithiophosphate) 298-577-9 93819-94-4
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
04/10/2018
04/10/2018
04/10/2018
19/11/2018
19/11/2018
19/11/2018
Details
Alkenes, C15-18 297-797-2 93762-80-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
25/06/2012
30/09/2011
30/09/2011
09/08/2012
Details
Phosphorous acid, tri-C12-14-alkyl esters 297-701-9 93686-48-7
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
16/02/2015
16/02/2015
02/04/2015
02/04/2015
Details
Hydrocarbons, C4, 1,3-butadiene-free, polymd., triisobutylene fraction, hydrogenated 297-629-8 93685-81-5 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C4, 1,3-butadiene-free, polymd., tetraisobutylene fraction, hydrogenated 297-628-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Ashes (residues), plant 297-049-5 93333-79-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2011
16/05/2011
16/05/2011
30/06/2011
30/06/2011
30/06/2011
Details
Ashes (residues), plant 297-049-5 93333-79-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Details
2-Naphthalenol, 1-[[4-(phenylazo)phenyl]azo]-, ar-heptyl ar',ar''-Me derivs. 296-120-8 92257-31-3 Genetic toxicity in vivo 16/12/2020 01/02/2021 Details
Rosin, fumarated, reaction products with glycerol and pentaerythritol 296-047-1 92202-14-7
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7)
Reproductive toxicity (two-generation reproductive toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS 94581-15-4)
Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS 97489-11-7); Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS 94581-15-4); and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS 94581-17-6)
19/07/2013
19/07/2013
02/07/2013
19/07/2013
02/07/2013
02/09/2013
02/09/2013
16/08/2013
02/09/2013
16/08/2013
Details
Rosin, fumarated, reaction products with glycerol and pentaerythritol 296-047-1 92202-14-7 Reproductive toxicity (pre-natal developmental toxicity) 16/07/2012 30/08/2012 Details
Resin acids and Rosin acids, reaction products with formaldehyde, potassium salt 295-855-1 92129-53-8 Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), and Rosin, reaction products with formaldehyde (CAS RN 91081-53-7) 02/07/2013 16/08/2013 Details
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides 295-714-4 92128-22-8 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides 295-714-4 92128-22-8 Reproductive toxicity (pre-natal developmental toxicity) 28/02/2018 16/04/2018 Details
dihydro-3-(tripropenyl)furan-2,5-dione 295-556-6 92077-08-2 Reproductive toxicity (pre-natal developmental toxicity) 30/09/2015 16/11/2015 Details
Residues (petroleum), thermal cracked vacuum 295-518-9 92062-05-0
Genetic toxicity in vivo||Note: testing proposed with Asphalt (EC no. 232-490-9)
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Asphalt (EC no. 232-490-9)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Asphalt (EC no. 232-490-9)
Sub-chronic toxicity (90-day): oral||Note: testing proposed with Asphalt (EC no. 232-490-9)
04/12/2023
04/12/2023
04/12/2023
04/12/2023
18/01/2024
18/01/2024
18/01/2024
18/01/2024
Details
Residues (petroleum), thermal cracked vacuum 295-518-9 92062-05-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Details
Residues (petroleum), thermal cracked vacuum 295-518-9 062-05-0 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Asphalt (CAS 8052-42-4) 25/06/2019 09/08/2019 Details
Gas oils (petroleum), hydrotreated light vacuum 295-407-5 92045-24-4 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
Hydrocarbons, C4, steam-cracker distillate 295-405-4 92045-23-3
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1)
Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
Extracts (petroleum), deasphalted vacuum residue solvent 295-332-8 91995-70-9 Reproductive toxicity (two-generation reproductive toxicity) 29/07/2011 12/09/2011 Details
Extracts (petroleum), deasphalted vacuum residue solvent 295-332-8 91995-70-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
28/02/2019
28/02/2019
28/02/2019
15/04/2019
15/04/2019
15/04/2019
Details
Extracts (petroleum), deasphalted vacuum residue solvent 295-332-8 91995-70-9 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Extracts (petroleum), residual oil solvent (EC no. 265-110-5) 06/06/2023 21/07/2023 Details
Cobalt, borate propionate complexes 295-033-2 91782-61-5
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant.
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
Details
Cobalt, borate 2-ethylhexanoate complexes 295-032-7 91782-60-4
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant
07/07/2020
07/07/2020
21/08/2020
21/08/2020
Details
Tar, wood 294-436-0 91722-33-7 Reproductive toxicity (pre-natal developmental toxicity) 23/02/2022 12/04/2022 Details
Resin acids and Rosin acids, maleated, calcium salts 294-402-5 91722-01-9
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)
02/07/2013
02/07/2013
16/08/2013
16/08/2013
Details