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Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Reaction mass of 2,2'-[(4-methylphenyl)imino]bisethanol and Ethanol 2-[[2-(2-hydroxyethoxy)ethyl](4-methylphenyl)amino]- 911-490-9 - Sub-chronic toxicity (90-day): oral 27/05/2019 11/07/2019
Reaction mass of 2,2'-[(4-methylphenyl)imino]bisethanol and Ethanol 2-[[2-(2-hydroxyethoxy)ethyl](4-methylphenyl)amino]- 911-490-9 -
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
18/11/2014
18/11/2014
02/01/2015
02/01/2015
Reaction mass of 2,2',2''-nitrilotriethanol and disodium succinate and sodium acetate and sodium bromide 905-908-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
05/05/2014
05/05/2014
Reaction mass of 1-phenyloctadecane-1,3-dione and phenylicosane-1,3-dione 915-316-2 - Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012
Reaction mass of 1-chlorobut-2-ene and 3-chlorobut-1-ene 908-820-9 - Genetic toxicity in vivo 16/07/2012 30/08/2012
Reaction mass of 1-[2-(2-aminobutoxy)ethoxy]but-2-ylamine and 1-({[2-(2-aminobutoxy)ethoxy]methyl}propoxy)but-2-ylamine 447-920-2 - Reproductive toxicity (pre-natal developmental toxicity) 21/05/2018 05/07/2018
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt 939-650-3 - Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane 608-489-8 30499-70-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/06/2015
25/06/2015
25/06/2015
10/08/2015
10/08/2015
10/08/2015
Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane 608-489-8 - Genetic toxicity in vivo 03/02/2016 21/03/2016
Reaction mass of 1-(1-Methyl-2-(1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yloxy)ethoxy)-propan-2-ol and 1-(2-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yloxy)propoxy)-propan-2-ol and 2-(2-(1,7,7-trimethylbicyclo-[2.2.1]hept-2-yloxy]-propoxy)-propan-1-ol and 2-(1-Methyl-2-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yloxy)ethoxy)-propan-1-ol 470-680-5 958872-63-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-days): oral
21/01/2011
21/01/2011
07/03/2011
07/03/2011
Reaction mass of 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-dioxane-5,5-dimethanol 911-819-6 -
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/02/2011
14/02/2011
31/03/2011
31/03/2011
Reaction mass of 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-dioxane-5,5-dimethanol 911-819-6 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/08/2019
16/08/2019
30/09/2019
30/09/2019
Reaction mass of 1,3-Propanediamine, N-[3-(tridecyloxy)propyl]-, branched and 1,3-Propanediamine, N-[3-(tridecyloxy)propyl]-, branched acetate 931-295-2 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Reaction mass of (2S-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2R,4R) and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2S,4S) and (2R-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran 939-429-1 16409-43-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/11/2015
30/11/2015
14/01/2016
14/01/2016
Reaction mass of (2-azaniumylethyl)[3-(trimethoxysilyl)propyl]amine chloride (2-azaniumylethyl)(benzyl)[3-(trimethoxysilyl)propyl]amine chloride 3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 7-benzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-10-ium chloride 10-benzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 7,10-dibenzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 700-961-2 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Raffinates (Fischer-Tropsch), C10-25-branched - 1345668-40-7 Reproductive toxicity (two-generation reproductive toxicity) 17/08/2012 01/10/2012
Quaternary ammonium compounds, C12-18-alkylbis(hydroxyethyl)methyl, chlorides 276-038-9 71808-53-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, reaction products with polyethylenepolyamines and tall-oil fatty acids, humates hydrochlorides 272-745-1 68910-55-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
23/01/2015
23/01/2015
23/01/2015
23/01/2015
09/03/2015
09/03/2015
09/03/2015
09/03/2015
Pyridine, alkyl derivs. 269-929-9 68391-11-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 5-ethyl-2-methylpyridine 04/04/2014 19/05/2014
Propylidynetrimethyl trimethacrylate 221-950-4 3290-92-4 Reproductive toxicity (pre-natal developmental toxicity) 31/05/2016 15/07/2016
Propylidynetrimethyl trimethacrylate 221-950-4 3290-92-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/04/2019 10/06/2019
Propylidynetrimethanol, propoxylated 500-041-9 -
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with analogue substance
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with analogue substance
Sub-chronic toxicity (90-day): oral || Note: testing proposed with analogue substance
05/07/2018
05/07/2018
05/07/2018
20/08/2018
20/08/2018
20/08/2018
Propylidynetrimethanol 201-074-9 77-99-6 Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed on rabbits 16/05/2014 30/06/2014
Propylidynetrimethanol 201-074-9 77-99-6 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2011 30/06/2011
Propionaldehyde, reaction product with formaldehyde 701-281-9 - Genetic toxicity in vivo || Note: the EC/list number of the substance has been changed. 10/12/2018 24/01/2019
Product of Semi-Dry Absorption method of Flue Gas Desulphurization (SDA Product) 931-259-6 -
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
02/09/2011
02/09/2011
17/10/2011
17/10/2011
praseodymium(III,IV) oxide 234-857-9 12037-29-5 Genetic toxicity in vivo 18/09/2014 03/11/2014
potassium titanium oxide (K2Ti6O13) 432-240-0 12056-51-8 Long-term toxicity to fish 17/05/2017 03/07/2017
potassium tetrafluoroborate 237-928-2 14075-53-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Potassium salts of {hexane-1,6-diylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1)  701-184-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Potassium permanganate 231-760-3 7722-64-7 Reproductive toxicity (two-generation reproductive toxicity) 14/02/2011 31/03/2011
Potassium cyanate 209-676-3 590-28-3 Reproductive toxicity (two-generation reproductive toxicity) 01/07/2011 15/08/2011
Potassium cyanate 209-676-3 590-28-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
potassium 4-isopropylbenzenesulphonate 629-764-9 164524-02-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2015 10/08/2015
potassium 4-cumenesulfonate 629-764-9 164524-02-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) 16/12/2016 30/01/2017
potassium 4-cumenesulfonate 629-764-9 164524-02-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate  
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Polysulfo {5-hydroxy-1-naphthalen-2-yl-[4-[4-(2-sulfatoethyl-sulfonyl)-phenyl]diazenyl]-1H-pyrazole-3-carboxylic acid}, alkali metal salt - - Genetic toxicity in vivo 09/11/2009 24/12/2009
Polysulfides, di-tert-nonyl 270-336-2 68425-16-1 Sub-chronic toxicity (90-day): oral 06/09/2018 22/10/2018
Polysulfides, di-tert-dodecyl 270-335-7 68425-15-0 Bioaccumulation aquatic / sediment 16/02/2015 02/04/2015
Polysulfides, di-tert-dodecyl 270-335-7 68425-15-0 Bioaccumulation aquatic / sediment 01/07/2011 15/08/2011
Polysulfides, di-tert-dodecyl 270-335-7 68425-15-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
31/01/2018
19/03/2018
19/03/2018
19/03/2018
Polysulfides, di-tert-Bu 273-103-3 68937-96-2 Bioaccumulation aquatic / sediment 01/07/2011 15/08/2011
Polysulfides, bis[3-(triethoxysilyl)propyl] 915-673-4 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Polysulfides, bis[3-(triethoxysilyl)propyl] 915-673-4 - Reproductive/developmental toxicity 22/12/2010 07/02/2011
Polysulfides, bis[3-(triethoxysilyl)propyl] 915-673-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Polyphosphoric acids, esters with triethanolamine, sodium salts 268-625-3 68131-72-6
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
15/04/2014
15/04/2014
30/05/2014
30/05/2014
Poly[oxy(methyl-1,2-ethanediyl)], α,α'-(2,2-dimethyl-1,3-propanediyl)bis[ω-hydroxy-] 610-848-9 52479-58-0 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014
Poly[oxy(methyl-1,2-ethanediyl)], a-hydro-omega-hydroxy-, ether with 2,6 bis{[(2-hydroxyethyl)amino]methyl}-4-nonylphenol 614-668-1 68610-97-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/09/2015
30/09/2015
16/11/2015
16/11/2015
Poly-(1,4-diisopropylbenzol) 449-400-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Poly(oxy-1,2-ethanediyl), .alpha.-[3-[(carboxymethyl)methylamino]-2-hydroxypropyl]-.omega.-(4-nonylphenoxy)-, monosodium sal 616-248-3 75627-31-5
Reproductive toxicity (pre-natal developmental toxicity
Sub-chronic toxicity (90-day): oral
23/12/2015
23/12/2015
03/02/2016
03/02/2016
Poly(alkan-2-yl)heteropolycycle - - Genetic toxicity in vivo 31/01/2013 18/03/2013
Poly [oxy(methyl-1,2-ethanediyl)] , a -hydro-w -hydroxy-, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1), 3-[[3-dimethylamino) propyl]imino]butanoate 613-645-3 646505-36-4 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014
Pleuromulin 204-747-5 125-65-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/09/2018
06/09/2018
06/09/2018
22/10/2018
22/10/2018
22/10/2018
Pivalic acid 200-922-5 75-98-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/12/2017
20/12/2017
20/12/2017
05/02/2018
05/02/2018
05/02/2018
Phosphorous acid, tri-C12-14-alkyl esters 297-701-9 93686-48-7
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
16/02/2015
16/02/2015
02/04/2015
02/04/2015
Phosphorodithioic acid, mixed O,O-bis(sec-Bu and 1,3-dimethylbutyl) esters, zinc salts 272-238-5 68784-31-6
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category"
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category"
04/10/2018
04/10/2018
04/10/2018
19/11/2018
19/11/2018
19/11/2018
Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts 270-608-0 68457-79-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/09/2016
01/09/2016
01/09/2016
17/10/2016
17/10/2016
17/10/2016
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts 272-723-1 68909-93-3
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: substance to be tested is Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0; CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
Reproductive toxicity (pre-natal developmental toxicity) || Note: substance to be tested is Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0; CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
Sub-chronic toxicity (90-day): oral || Note: substance to be tested is Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0; CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
04/10/2018
04/10/2018
04/10/2018
19/11/2018
19/11/2018
19/11/2018
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu) esters, zinc salts 270-478-5 68442-22-8
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category"
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
04/10/2018
04/10/2018
04/10/2018
19/11/2018
19/11/2018
19/11/2018
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and pentyl) esters, zinc salts 273-527-9 68988-45-4
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
04/10/2018
04/10/2018
19/11/2018
19/11/2018
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and iso-Pr) esters, zinc salts 288-917-4 85940-28-9
"Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) ""Testing proposed according to a plan for the ZDDP category.“ "
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category"
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
04/10/2018
04/10/2018
04/10/2018
19/11/2018
19/11/2018
19/11/2018
Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts 283-392-8 84605-29-8
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category"
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category"
04/10/2018
04/10/2018
04/10/2018
19/11/2018
19/11/2018
19/11/2018
Phosphoric acid, octadecyl ester 254-466-7 39471-52-8
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
17/04/2015
17/04/2015
04/06/2015
04/06/2015
04/06/2015
04/06/2015
Phosphoric acid, mixed esters with Bu alc. and ethylene glycol 284-716-0 84962-20-9
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphoric acid, butyl ester; CAS No. 12788-93-1
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphoric acid, butyl ester; CAS No. 12788-93-1
20/05/2015
20/05/2015
06/07/2015
06/07/2015
Phosphoric acid, dodecyl ester, potassium salt 254-414-3 39322-78-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Phosphoric acid, butyl ester 235-826-2 12788-93-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
04/06/2015
04/06/2015
Phosphonium, tetrakis(hydroxymethyl)-, chloride (1:1), reaction products with 1-tetradecanamine and urea 436-230-7 359406-89-6 Sub-chronic toxicity (90-day): oral 06/03/2012 20/04/2012
Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide 423-340-5 162881-26-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
22/12/2010
22/12/2010
22/12/2010
07/02/2011
07/02/2011
07/02/2011
Phenol, methylstyrenated 270-966-8 68512-30-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Phenol, isopropylated, phosphate (3:1) 273-066-3 68937-41-7
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
29/07/2011
29/07/2011
29/07/2011
12/09/2011
12/09/2011
12/09/2011
12/09/2011
12/09/2011
Phenol, isopropylated, phosphate (3:1) 273-066-3 68937-41-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Phenol, 4,4'-(1-methylethylidene)bis-, oligomeric reaction products with 2-(chloromethyl)oxirane, reaction products with 1,3-benzenedimethanamine 500-302-7 113930-69-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
Peroxyacetic acid, reaction products with N2,N2’-1,6-hexanediylbis[N4,N6-dibutyl-N2,N4,N6-tris(2,2,6,6,tetramethyl-4-piperidinyl)-1,3,5-triazine-2,4,6-triamine, hydrogenated 812-927-5 1902936-62-2 Reproductive toxicity (pre-natal developmental toxicity) 10/08/2018 24/09/2018
Perfluoroethane 200-939-8 76-16-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
Perfluamine 206-420-2 338-83-0
Genetic toxicity in vivo (In vivo Mammalian Alkaline Comet Assay)
Genetic toxicity in vivo (Mammalian Erythrocyte Micronucleus Test)
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
29/03/2019
29/03/2019
29/03/2019
29/03/2019
13/05/2019
13/05/2019
13/05/2019
13/05/2019
Pentasodium triphosphate 231-838-7 7758-29-4 Sub-chronic toxicity (90-day) via the inhalatory route (rat) 08/04/2010 24/05/2010
pentasodium 5-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}-3-[2-(1,5-disulfonaphthalen-2-yl)diazen-1-yl]-4-hydroxynaphthalene-2,7-disulfonate 402-420-3 89157-03-9 Sub-chronic toxicity (90-day): oral 25/06/2019 09/08/2019
Pentane-2,4-dione 204-634-0 123-54-6
Long-term toxicity to fish
Reproductive toxicity (two-generation reproductive toxicity)
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Pentane-1,2-diol 226-285-3 5343-92-0 Sub-chronic toxicity (90-day): oral 16/06/2011 01/08/2011
Pentan-3-one 202-490-3 96-22-0 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011
Pentan-2-one 203-528-1 107-87-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Pentaerythritol, reaction product with fatty acids, C8 to 18 (even numbered) and/or branched and/or unsaturated 484-420-3 - Reproductive toxicity (pre-natal developmental toxicity) 30/04/2012 14/06/2012
Pentaerythritol tetrakis(3-mercaptopropionate) 231-472-8 7575-23-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
01/07/2011
01/07/2011
01/07/2011
15/08/2011
15/08/2011
15/08/2011
pentaerythritol 204-104-9 115-77-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
20/12/2017
20/12/2017
05/02/2018
05/02/2018
Paraffins (petroleum), normal C>10 265-232-9 64771-71-7 Reproductive toxicity (two-generation reproductive toxicity) 15/09/2011 31/10/2011
p-tert-butylphenyl 1-(2,3-epoxy)propyl ether 221-453-2 3101-60-8
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2014
17/06/2014
17/06/2014
17/06/2014
01/08/2014
01/08/2014
01/08/2014
01/08/2014
p-phenylenediammine 203-404-7 106-50-3 Long-term toxicity testing to fish 26/01/2011 14/03/2011
p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline 225-716-2 5026-74-4
Genetic toxicity in vivo || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline 225-716-2 5026-74-4
Genetic toxicity in vivo || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Oxydipropyl dibenzoate 248-258-5 27138-31-4 Long-term toxicity to fish 10/08/2018 24/09/2018
Oxalaldehyde 203-474-9 107-22-2
Chronic toxicity / carcinogenicity
Reproductive toxicity (two-generation reproductive toxicity)
05/04/2011
05/04/2011
20/05/2011
20/05/2011
Orthoboric acid, compound with 2-aminoethanol 247-421-8 26038-87-9 Repeated dose toxicity (90-day): oral 17/11/2011 02/01/2012
Orthoboric acid, compound with 2-aminoethanol 247-421-8 26038-87-9
Long-term or reproductive toxicity to birds
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
orthoboric acid, compound with 2,2'-iminodiethanol 267-886-0 67952-33-4
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with MEA Polyborate
Sub-chronic toxicity (90-day): oral || Note: testing proposed with MEA Polyborate
30/11/2015
30/11/2015
14/01/2016
14/01/2016
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate 252-029-5 34443-12-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
21/03/2014
05/05/2014
05/05/2014
05/05/2014
Oligomerisation reaction products of glyoxal and urea 610-945-6 53037-34-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
octyltrichlorosilane 226-112-1 5283-66-9 Sub-chronic toxicity (90-day): oral || Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) 25/06/2015 10/08/2015
Octylphosphonic acid 225-218-5 4724-48-5 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014
Octene, hydroformylation products, low-boiling 273-110-1 68938-03-4 Genetic toxicity in vivo 17/06/2014 01/08/2014
Octene, hydroformylation products, high-boiling 271-237-7 68526-89-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011



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