Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Ukazujem 401 - 600 z 1 996 výsledkov.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
Cobalt oxalate	212-409-3	814-89-1	Carcinogenicity \|\| Note: testing proposed with Cobalt dichloride (EC 231-589-4) \|\| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo \|\| Note: testing proposed with Cobalt sulphate (EC 233-334-2) \|\| Note: Testing proposal is based on concern identified by the registrant.	21/09/2020 21/09/2020	05/11/2020 05/11/2020	Details
Triethyl phosphonoacetate	212-757-6	867-13-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014	29/08/2014 29/08/2014	Details
Dec-1-ene	212-819-2	872-05-9	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	31/05/2011 31/05/2011 25/06/2012	15/07/2011 15/07/2011 09/08/2012	Details
Vinylene carbonate	212-825-5	872-36-6	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	20/05/2021 20/05/2021 20/05/2021	05/07/2021 05/07/2021 05/07/2021	Details
Vinylene carbonate	212-825-5	872-36-6	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
3,3,5-trimethylcyclohexan-1-one	212-855-9	873-94-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/07/2011 29/07/2011	12/09/2011 12/09/2011	Details
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol	212-985-6	901-44-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	27/01/2020 27/01/2020	12/03/2020 12/03/2020	Details
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol	212-985-6	901-44-0	Long-term toxicity to fish	22/09/2022	07/11/2022	Details
2,5-bis(1,1,3,3-tetramethylbutyl)hydroquinone	212-990-3	903-19-5	Genetic toxicity in vivo	16/12/2020	01/02/2021	Details
Sodium 1-hydroxyethanesulphonate	213-037-4	918-04-7	Genetic toxicity in vivo	25/05/2020	09/07/2020	Details
3-aminopropyltriethoxysilane	213-048-4	919-30-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	18/03/2021 18/03/2021	03/05/2021 03/05/2021	Details
Dimethyl(propyl)amine	213-139-9	926-63-6	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Ethyldimethylamine (EC 209-940-8) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Ethyldimethylamine (EC 209-940-8)	18/02/2021 18/02/2021	05/04/2021 05/04/2021	Details
tert-butyl peroxypivalate	213-147-2	927-07-1	Reproductive toxicity (pre-natal developmental toxicity)	21/03/2014	05/05/2014	Details
1-(vinyloxy)octadecane	213-208-3	930-02-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
2-ethyl-4-methylimidazole	213-234-5	931-36-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/04/2014 15/04/2014	30/05/2014 30/05/2014	Details
N-phenylmaleimide	213-382-0	941-69-5	Genetic toxicity in vivo	29/04/2011	14/06/2011	Details
(1-hydroxycyclohexyl) (phenyl)methanone (hydroxycyclohexyl phenyl ketone)	213-426-9	947-19-3	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	28/02/2011 28/02/2011 28/02/2011	14/04/2011 14/04/2011 14/04/2011	Details
Hydroxycyclohexyl phenyl ketone	213-426-9	947-19-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	17/09/2019	01/11/2019	Details
3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	213-485-0	957-68-6	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	10/08/2018 10/08/2018 10/08/2018	24/09/2018 24/09/2018 24/09/2018	Details
bis(piperidinothiocarbonyl) hexasulphide	213-537-2	971-15-3	Reproductive toxicity (pre-natal developmental toxicity)	29/04/2014	13/06/2014	Details
bis(piperidinothiocarbonyl) hexasulphide	213-537-2	971-15-3	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	16/02/2015	02/04/2015	Details
Methylphosphonic acid	213-607-2	993-13-5	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4)	27/05/2019 27/05/2019	11/07/2019 11/07/2019	Details
1,1,1,3,3,3-hexamethyldisilazane	213-668-5	999-97-3	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with Hydroxytrimethylsilane (EC no. 213-914-1) Reproductive toxicity (pre-natal developmental toxicity)\|\| Note: testing proposed with Hydroxytrimethylsilane (EC no. 213-914-1)	16/06/2022 16/06/2022	01/08/2022 01/08/2022	Details
1-ethoxy-2-(2-methoxyethoxy)ethane	213-690-5	1002-67-1	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	25/05/2020 25/05/2020 25/05/2020	09/07/2020 09/07/2020 09/07/2020	Details
1,3,5-triallyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione	213-834-7	1025-15-6	Reproductive toxicity (pre-natal developmental toxicity)	25/09/2012	12/11/2012	Details
Trimethoxypropylsilane	213-926-7	1067-25-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	06/06/2023 06/06/2023	21/07/2023 21/07/2023	Details
tris(2-methoxyethoxy)vinylsilane	213-934-0	1067-53-4	Reproductive toxicity (pre-natal developmental toxicity)	29/07/2011	12/09/2011	Details
Adipohydrazide	213-999-5	1071-93-8	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/01/2014 31/01/2014	17/03/2014 17/03/2014	Details
Cyclohexane-1,4-dicarboxylic acid	214-068-6	1076-97-7	Reproductive toxicity (pre-natal developmental toxicity)	27/11/2013	10/01/2014	Details
dimethoxydimethylsilane	214-189-4	1112-39-6	Sub-chronic toxicity (90 day): inhalation	16/10/2014	01/12/2014	Details
dimethoxydimethylsilane	214-189-4	1112-39-6	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	28/11/2022 28/11/2022	12/01/2023 12/01/2023	Details
3-hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2-dimethylpropionate	214-222-2	1115-20-4	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/05/2011 31/05/2011 31/05/2011	15/07/2011 15/07/2011 15/07/2011	Details
n-butyltin trichloride	214-263-6	1118-46-3	Reproductive toxicity (pre-natal developmental toxicity)	29/04/2011	14/06/2011	Details
Undecane	214-300-6	1120-21-4	Reproductive toxicity (two-generation reproductive toxicity)	25/06/2012	09/08/2012	Details
Tetradec-1-ene	214-306-9	1120-36-1	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	31/05/2011 31/05/2011 25/06/2012	15/07/2011 15/07/2011 09/08/2012	Details
N-butyl phenyl ether	214-426-1	1126-79-0	Long-term toxicity to fish	03/04/2023	22/05/2023	Details
4-hydroxybenzophenone	214-507-1	1137-42-4	Genetic toxicity in vivo	18/02/2021	05/04/2021	Details
Naphthalene-2,6-dicarboxylic acid	214-527-0	1141-38-4	Reproductive toxicity (pre-natal developmental toxicity)	16/06/2022	01/08/2022	Details
Trimethylamine, N-oxide	214-675-6	1184-78-7	Genetic toxicity in vivo\|\|Note: testing proposed with Reference substance 001 [CAS No. 62637-93-8]	06/06/2023	21/07/2023	Details
Trimethoxy(methyl)silane	214-685-0	1185-55-3	Reproductive toxicity (extended one-generation reproductive toxicity study Reproductive toxicity (pre-natal developmental toxicity)	12/04/2017 12/04/2017	29/05/2017 29/05/2017	Details
Trifluoro(trifluoromethoxy)ethylene	214-703-7	1187-93-5	Sub-chronic toxicity (90 day): inhalation	29/04/2014	13/06/2014	Details
4-chloroformylphthalic anhydride	214-874-8	1204-28-0	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	27/01/2020	12/03/2020	Details
α-methyl-1,3-benzodioxole-5-propionaldehyde	214-881-6	1205-17-0	Reproductive toxicity (extended one-generation reproductive toxicity study)	31/01/2023	17/03/2023	Details
Dichlorobis(η-cyclopentadienyl)titanium	215-035-9	1271-19-8	Genetic toxicity in vivo	25/05/2020	09/07/2020	Details
Sodium xylenesulphonate	215-090-9	1300-72-7	Reproductive toxicity (two-generation reproductive toxicity)	15/07/2014	29/08/2014	Details
Dibismuth trioxide	215-134-7	1304-76-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/04/2011 29/04/2011	14/06/2011 14/06/2011	Details
bismuth hydroxide nitrate oxide	215-136-8	1304-85-4	Sub-chronic toxicity (90-day): oral	18/09/2014	03/11/2014	Details
Cobalt oxide	215-154-6	1307-96-6	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	02/09/2011 02/09/2011 02/09/2011	17/10/2011 17/10/2011 17/10/2011	Details
Cobalt oxide	215-154-6	1307-96-6	Carcinogenicity \|\| Note: testing proposed with Cobalt dichloride (EC 231-589-4) Genetic toxicity in vivo \|\| Note: testing proposed with Cobalt sulphate (EC 233-334-2)	21/01/2021 21/01/2021	08/03/2021 08/03/2021	Details
Tricobalt tetraoxide	215-157-2	1308-06-1	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	02/09/2011 02/09/2011 02/09/2011	17/10/2011 17/10/2011 17/10/2011	Details
Tricobalt tetraoxide	215-157-2	1308-06-1	Genetic toxicity in vivo \|\| Note: testing proposed with Cobalt sulphate (EC 233-334-2) \|\| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Cobalt sulphide (EC 215-273-3) \|\| Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90 day): inhalation	21/09/2020 21/09/2020 21/09/2020	05/11/2020 05/11/2020 05/11/2020	Details
Lithium hydroxide	215-183-4	1310-65-2	Reproductive toxicity (two-generation reproductive toxicity)	29/04/2011	14/06/2011	Details
Manganese dioxide	215-202-6	1313-13-9	Genetic toxicity in vivo	23/11/2020	07/01/2021	Details
Strontium oxide	215-219-9	1314-11-0	Reproductive toxicity (pre-natal developmental toxicity)	25/06/2019	09/08/2019	Details
Zirconium dioxide	215-227-2	1314-23-4	Reproductive toxicity (pre-natal developmental toxicity)	15/04/2011	30/05/2011	Details
Ytterbium (III) oxide	215-234-0	1314-37-0	Genetic toxicity in vivo	23/11/2020	07/01/2021	Details
Divanadium pentaoxide	215-239-8	1314-62-1	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with sodium metavanadate (EC no. 237-272-7) Reproductive toxicity (pre-natal developmental toxicity)\|\| Note: testing proposed with sodium metavanadate (EC no. 237-272-7)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
Cobalt sulphide	215-273-3	1317-42-6	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	02/09/2011 02/09/2011 02/09/2011	17/10/2011 17/10/2011 17/10/2011	Details
Cobalt sulphide	215-273-3	1317-42-6	Genetic toxicity in vivo \|\| Note: testing proposed with Cobalt sulphate (EC 233-334-2) \|\| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90 day): inhalation \|\| Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2) \|\| Note: Testing proposal is based on concern identified by the registrant	21/09/2020 21/09/2020 21/09/2020	05/11/2020 05/11/2020 05/11/2020	Details
Xylene	215-535-7	1330-20-7	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with Reaction mass of ethylbenzene and xylene (EC No 905-588-0)	01/03/2023	17/04/2023	Details
Xylene	215-535-7	1330-20-7	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with Reaction mass of ethylbenzene and xylene (EC no. 905-588-0)	31/01/2023	17/03/2023	Details
Tris(methylphenyl) phosphate	215-548-8	1330-78-5	Bioaccumulation: aquatic / sediment; Long-term toxicity to fish	02/09/2011 02/09/2011	17/10/2011 17/10/2011	Details
Dioxydibutane-2,2-diyl dihydroperoxide	215-661-2	1338-23-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/04/2011 29/04/2011	14/06/2011 14/06/2011	Details
Naphthenic acids	215-662-8	1338-24-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	04/04/2014 04/04/2014	19/05/2014 19/05/2014	Details
Naphthenic acids	215-662-8	1338-24-5	Long-term toxicity to fish	01/07/2011	15/08/2011	Details
Aluminium oxide	215-691-6	1344-28-1	Genetic toxicity in vivo \|\| Note: Testing proposal for two in vivo studies is based on concern identified by the registrant. Testing proposed with Aluminium oxide nanoscale material.	28/02/2018	16/04/2018	Details
4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol; bisphenol AF	216-036-7	1478-61-1	Genetic toxicity in vivo	23/11/2020	07/01/2021	Details
Cobalt(2+) propionate	216-333-1	1560-69-6	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	02/09/2011 02/09/2011 02/09/2011	17/10/2011 17/10/2011 17/10/2011	Details
[1R-(1α,2β,5α)]-1-(isopropyl)-2-methoxy-4-methylcyclohexane	216-365-6	1565-76-0	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	19/10/2020	03/12/2020	Details
1-hydroxy-4-[[4-[(methylsulphonyl)oxy]phenyl]amino]anthraquinone	216-475-4	1594-08-7	Genetic toxicity in vivo	01/07/2021	16/08/2021	Details
Strontium carbonate	216-643-7	1633-05-2	Long-term toxicity to fish	31/05/2011	15/07/2011	Details
chlorodimethylvinylsilane	217-007-1	1719-58-0	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Trimethylsilanol (CAS 1066-40-6)	12/12/2014	26/01/2015	Details
1,2-dimethylimidazole	217-101-2	1739-84-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	19/10/2020 19/10/2020	03/12/2020 03/12/2020	Details
1,2-dimethylimidazole	217-101-2	1739-84-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
p-tert-butylstyrene	217-126-9	1746-23-2	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: Testing proposal is based on concern identified by the registrant.	25/05/2020	09/07/2020	Details
Aminoiminomethanesulphinic acid	217-157-8	1758-73-2	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	16/05/2014 16/05/2014	30/06/2014 30/06/2014	Details
N-(3-(trimethoxysilyl)propyl)ethylenediamine	217-164-6	1760-24-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	03/03/2014 03/03/2014	17/04/2014 17/04/2014	Details
Octabenzone	217-421-2	1843-05-6	Reproductive toxicity (pre-natal developmental toxicity)	18/02/2013	04/04/2013	Details
2-ethyl-N,N-bis(2-ethylhexyl)hexylamine	217-461-0	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/01/2012 16/01/2012	01/03/2012 01/03/2012	Details
1,1,1,3,5,5,5-heptamethyltrisiloxane	217-496-1	1873-88-7	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with Octamethyltrisiloxane, CAS 107-51-7 and 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7 Sub-chronic toxicity (90 day): inhalation Note: testing proposed with 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7.	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
6-tert-butyl-2,4-xylenol	217-533-1	1879-09-0	Long-term toxicity to fish	15/07/2014	29/08/2014	Details
6-tert-butyl-2,4-xylenol	217-533-1	1879-09-0	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity)	18/02/2021 18/02/2021	05/04/2021 05/04/2021	Details
N-acetylhexanelactam	217-565-6	1888-91-1	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposal is based on concern identified by the registrant	17/06/2020	03/08/2020	Details
1,1'-(1,1,2,2-tetramethylethylene)dibenzene	217-568-2	1889-67-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
OO-tert-butyl monoperoxymaleate	217-691-1	1931-62-0	Genetic toxicity in vivo	23/11/2020	07/01/2021	Details
triethoxy(methyl)silane	217-983-9	2031-67-6	Sub-chronic toxicity (90-day): oral	25/05/2020	09/07/2020	Details
triethoxy(methyl)silane	217-983-9	2031-67-6	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with trimethoxy(methyl)silane.	16/10/2014	01/12/2014	Details
N-butyl 4-oxopentanoate	218-143-4	2052-15-5	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Levulinic acid (EC 204-649-2) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Levulinic acid (EC 204-649-2)	23/11/2020 23/11/2020	07/01/2021 07/01/2021	Details
Vinyl laurate	218-414-7	2146-71-6	Sub-chronic toxicity (90-day): oral	16/05/2011	30/06/2011	Details
Dibutyl itaconate	218-451-9	2155-60-4	Genetic toxicity in vivo Sub-chronic toxicity (90-day): oral	24/02/2020 24/02/2020	09/04/2020 09/04/2020	Details
Bis(2,6-diisopropylphenyl)carbodiimide	218-487-5	2162-74-5	Reproductive toxicity (pre-natal developmental toxicity)	22/09/2022	07/11/2022	Details
2,3-epoxypropyl o-tolyl ether	218-645-3	2210-79-9	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/05/2014 16/05/2014 16/05/2014	30/06/2014 30/06/2014 30/06/2014	Details
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	218-664-7	2212-81-9	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposal is based on concern identified by the registrant	20/10/2016 20/10/2016	05/12/2016 05/12/2016	Details
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	218-664-7	2212-81-9	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/05/2012 16/05/2012 16/05/2012	02/07/2012 02/07/2012 02/07/2012	Details
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	218-664-7	2212-81-9	Reproductive toxicity (extended one-generation reproductive toxicity study) “\|\| Note: testing proposed with [1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide CAS: 25155-25-3)”	25/05/2020	09/07/2020	Details
Zinc O,O,O',O'-tetrakis(1,3-dimethylbutyl) bis(phosphorodithioate)	218-679-9	2215-35-2	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with, zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Zinc O,O,O',O'-tetrakis(1,3-dimethylbutyl) bis(phosphorodithioate)	218-679-9	2215-35-2	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Testing proposed according to a plan for the ZDDP category Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Testing proposed according to a plan for the ZDDP category. Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Testing proposed according to a plan for the ZDDP category.“	04/10/2018 04/10/2018 04/10/2018	19/11/2018 19/11/2018 19/11/2018	Details
butan-2-one O,O',O''-(vinylsilylidyne)trioxime	218-747-8	2224-33-1	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with Butan-2-one O,O',O''-(methylsilylidyne)trioxime (CAS 22984-54-9).	25/06/2015	10/08/2015	Details
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl	218-760-9	2226-96-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	14/08/2014 14/08/2014	28/09/2014 28/09/2014	Details
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl	218-760-9	2226-96-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/02/2015 16/02/2015	02/04/2015 02/04/2015	Details
N-phenyl-N-[(trichloromethyl)thio]benzenesulphonamide	218-915-0	2280-49-1	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
Octyl octanoate	218-980-5	2306-88-9	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	03/04/2023 03/04/2023 03/04/2023	22/05/2023 22/05/2023 22/05/2023	Details
2,4,6,8-tetramethylcyclotetrasiloxane	219-137-4	2370-88-9	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/05/2020	09/07/2020	Details
2,4,6,8-tetramethylcyclotetrasiloxane	219-137-4	2370-88-9	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation	15/09/2011 15/09/2011 15/09/2011	31/10/2011 31/10/2011 31/10/2011	Details
2,4,6,8-tetramethylcyclotetrasiloxane	219-137-4	2370-88-9	Sub-chronic toxicity (90-day): oral -	22/11/2017 22/11/2017	08/01/2018 08/01/2017	Details
Benzophenone-3,3':4,4'-tetracarboxylic dianhydride	219-348-1	2421-28-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	14/08/2014 14/08/2014	28/09/2014 28/09/2014	Details
2-Hexyldecan-1-ol	219-370-1	2425-77-6	Reproductive toxicity (two-generation reproductive toxicity)	05/04/2011	20/05/2011	Details
1,4-bis(2,3-epoxypropoxy)butane	219-371-7	2425-79-8	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane (1:2) (EC 618-939-5)	23/03/2020	07/05/2020	Details
1,4-bis(2,3-epoxypropoxy)butane	219-371-7	2425-79-8	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): most appropriate route	14/02/2011 14/02/2011 14/02/2011	31/03/2011 31/03/2011 31/03/2011	Details
11-aminoundecanoic acid	219-417-6	2432-99-7	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
11-aminoundecanoic acid	219-417-6	2432-99-7	Reproductive toxicity (developmental toxicity)	08/04/2010	24/05/2010	Details
2-(2H-benzotriazol-2-yl)-p-cresol	219-470-5	2440-22-4	Bioaccumulation aquatic / sediment	18/06/2018	02/08/2018	Details
1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione (TGIC)	219-514-3	2451-62-9	Reproductive toxicity (two-generation reproductive toxicity)	19/11/2010	03/01/2011	Details
Strontium bis(2-ethylhexanoate)	219-536-3	2457-02-5	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with [strontium oxide] (EC 215-219-9)	23/11/2020	07/01/2021	Details
3-(trimethoxysilyl)propiononitrile	219-764-3	2526-62-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	21/03/2014 21/03/2014	05/05/2014 05/05/2014	Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane	219-784-2	2530-83-8	Genetic toxicity in vivo	16/02/2015	02/04/2015	Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane	219-784-2	2530-83-8	Genetic toxicity in vivo	01/08/2012	17/09/2012	Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane	219-784-2	2530-83-8	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	17/06/2020	03/08/2020	Details
3-trimethoxysilylpropyl methacrylate	219-785-8	2530-85-0	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): inhalation	15/04/2011 15/04/2011	30/05/2011 30/05/2011	Details
3-trimethoxysilylpropyl methacrylate	219-785-8	2530-85-0	Reproductive toxicity (pre-natal developmental toxicity)	26/04/2019	10/06/2019	Details
3-trimethoxysilylpropyl methacrylate	219-785-8	2530-85-0	Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study)	01/09/2017 01/09/2017	16/10/2017 16/10/2017	Details
3-chloropropyltrimethoxysilane	219-787-9	2530-87-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
2,2'-methylenediphenyl diisocyanate	219-799-4	2536-05-2	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	01/04/2022	16/05/2022	Details
Triethoxypropylsilane	219-842-7	2550-02-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation	03/03/2014 03/03/2014	17/04/2014 17/04/2014	Details
4-phenylbutan-2-one	219-847-4	2550-26-7	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with a read-across substance having similar formula structure and its carbon chain consists of even number of carbons	22/11/2017	08/01/2018	Details
2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane	219-863-1	2554-06-5	Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation	03/03/2014 03/03/2014 03/03/2014 03/03/2014	17/04/2014 17/04/2014 17/04/2014 17/04/2014	Details
Dimethyl 2,2'-azobis(2-methylpropionate)	219-976-6	2589-57-3	Genetic toxicity in vivo	17/06/2020	03/08/2020	Details
[3-(2,3-epoxypropoxy)propyl]triethoxysilane	220-011-6	2602-34-8	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
1,1,3,3-tetramethyl-1,3-divinyldisiloxane	220-099-6	2627-95-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
N-ethyl-2-pyrrolidone (NEP)	220-250-6	2687-91-4	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day) via the inhalatory route	26/01/2011 26/01/2011	14/03/2011 14/03/2011	Details
Allyl 3-cyclohexylpropionate	220-292-5	2705-87-5	Reproductive toxicity (pre-natal developmental toxicity)	26/10/2022	12/12/2022	Details
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate	220-482-8	2781-11-5	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	27/01/2020	12/03/2020	Details
4-[[4-(aminocarbonyl)phenyl]azo]-N-(2-ethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide – nano form	220-509-3	2786-76-7	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with [3-hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide] (EC no. 229-440-3)	03/10/2023	17/11/2023	Details
N-(1,1-dimethyl-3-oxobutyl)acrylamide	220-713-2	2873-97-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	03/03/2014 03/03/2014	17/04/2014 17/04/2014	Details
2,2,6,6-tetramethyl-4-oxopiperidinooxy	220-778-7	2896-70-0	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2)	14/08/2014 14/08/2014	28/09/2014 28/09/2014	Details
2,2,6,6-tetramethyl-4-oxopiperidinooxy	220-778-7	2896-70-0	Sub-chronic toxicity (90-day): oral	03/04/2023	22/05/2023	Details
[3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane	220-780-8	2897-60-1	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	16/12/2016	30/01/2017	Details
Triethoxyoctylsilane	220-941-2	2943-75-1	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	27/09/2017 27/09/2017 27/09/2017	13/11/2017 13/11/2017 13/11/2017	Details
Triethoxyoctylsilane	220-941-2	2943-75-1	Long-term toxicity to fish \|\| Note: testing proposed with Triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1)	17/04/2015	04/06/2015	Details
Trimethoxyphenylsilane	221-066-9	2996-92-1	Reproductive toxicity (pre-natal developmental toxicity)	03/03/2014	17/04/2014	Details
2,2'-azobis[2-methylpropionamidine] dihydrochloride	221-070-0	2997-92-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	05/07/2018 05/07/2018	20/08/2018 20/08/2018	Details
3,9-dimethyl-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-dioxide	221-088-9	3001-98-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/12/2020 16/12/2020	01/02/2021 01/02/2021	Details
tert-butyl 2-ethylperoxyhexanoate	221-110-7	3006-82-4	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/04/2011 15/04/2011 15/04/2011	30/05/2011 30/05/2011 30/05/2011	Details
Cyclohexylidenebis[tert-butyl] peroxide	221-111-2	3006-86-8	Sub-chronic toxicity (90-day): oral	21/03/2014	05/05/2014	Details
bis(2-dimethylaminoethyl)(methyl)amine	221-201-1	3030-47-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	03/03/2014 03/03/2014	17/04/2014 17/04/2014	Details
hex-3-yne-2,5-diol	221-209-5	3031-66-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
3-ethyloxetane-3-methanol	221-254-0	3047-32-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/01/2014 31/01/2014	17/03/2014 17/03/2014	Details
3-ethyloxetane-3-methanol	221-254-0	3047-32-3	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
Tetra(isobutyl)thioperoxydicarbamic acid	221-312-5	3064-73-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/06/2018 18/06/2018	02/08/2018 02/08/2018	Details
N-[3-(dimethoxymethylsilyl)propyl]ethylenediamine	221-336-6	3069-29-2	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3. Sub-chronic toxicity (90-day): oral Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3.	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
trimethoxyoctylsilane	221-338-7	3069-40-7	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (CAS 35435-21-3)	07/08/2015	22/09/2015	Details
Trimethoxyoctylsilane	221-338-7	3069-40-7	Reproductive toxicity (extended one-generation reproductive toxicity study \|\| Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)	27/09/2017 27/09/2017	13/11/2017 13/11/2017	Details
p-tert-butylphenyl 1-(2,3-epoxy)propyl ether	221-453-2	3101-60-8	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	17/06/2014 17/06/2014 17/06/2014 17/06/2014	01/08/2014 01/08/2014 01/08/2014 01/08/2014	Details
2-methoxyethyl acrylate	221-499-3	3121-61-7	Genetic toxicity in vivo	21/03/2014	05/05/2014	Details
2-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol	221-573-5	3147-75-9	Bioaccumulation aquatic / sediment	15/07/2014	29/08/2014	Details
Furan-2,5-dicarboxylic acid	221-800-8	3238-40-2	Reproductive toxicity (pre-natal developmental toxicity)	27/05/2019	11/07/2019	Details
1,1,3,3-tetramethyldisiloxane	221-906-4	3277-26-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	29/04/2016 29/04/2016	13/06/2016 13/06/2016	Details
Propylidynetrimethyl trimethacrylate	221-950-4	3290-92-4	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/04/2019	10/06/2019	Details
Propylidynetrimethyl trimethacrylate	221-950-4	3290-92-4	Reproductive toxicity (pre-natal developmental toxicity)	31/05/2016	15/07/2016	Details
3,5,5-trimethylhexanoic acid	221-975-0	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/05/2011 31/05/2011	15/07/2011 15/07/2011	Details
sodium O,O-diethyl dithiophosphate \|\| Note: testing proposed with sodium O,O-diisobutyl dithiophosphate (EC 258-508-5)	222-079-2	3338-24-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
tert-pentyl hydroperoxide	222-321-7	3425-61-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	07/10/2016 07/10/2016	21/11/2016 21/11/2016	Details
tert-pentyl hydroperoxide	222-321-7	3425-61-4	Genetic toxicity in vivo	21/03/2014	05/05/2014	Details
Bisisobutyryl peroxide	222-340-0	3437-84-1	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	04/04/2014 04/04/2014 04/04/2014	19/05/2014 19/05/2014 19/05/2014	Details
1-(2-hydroxyethyl)pyrrolidin-2-one	222-359-4	3445-11-2	Reproductive toxicity (pre-natal developmental toxicity)	14/08/2014	28/09/2014	Details
1-(2-hydroxyethyl)pyrrolidin-2-one	222-359-4	3445-11-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/12/2020 16/12/2020 16/12/2020	01/02/2021 01/02/2021 01/02/2021	Details
Icos-1-ene	222-374-6	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
tert-butyl α,α-dimethylbenzyl peroxide	222-389-8	3457-61-2	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	16/03/2015	30/04/2015	Details
tert-butyl α,α-dimethylbenzyl peroxide	222-389-8	3457-61-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014	29/08/2014 29/08/2014	Details
1-imino-1H-isoindol-3-amine	222-426-8	3468-11-9	Genetic toxicity in vivo	27/01/2020	12/03/2020	Details
1-imino-1H-isoindol-3-amine	222-426-8	3468-11-9	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
1-butylpyrrolidin-2-one	222-437-8	3470-98-2	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/01/2022	11/03/2022	Details
N-butylbenzenesulphonamide	222-823-6	3622-84-2	Reproductive toxicity (pre-natal developmental toxicity)	14/02/2011	31/03/2011	Details
N-butylbenzenesulphonamide	222-823-6	3622-84-2	Reproductive toxicity (pre-natal developmental toxicity)	29/02/2016	14/04/2016	Details
Dioctyltin dilaurate	222-883-3	3648-18-8	Reproductive toxicity (pre-natal developmental toxicity)	23/03/2020	07/05/2020	Details
Diundecyl phthalate	222-884-9	3648-20-2	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
Octa-1,7-diene	223-054-9	3710-30-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
bis(3,5,5-trimethylhexanoyl) peroxide	223-356-0	3851-87-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014	29/08/2014 29/08/2014	Details
Bumetrizole	223-445-4	3896-11-5	Bioaccumulation aquatic / sediment	18/06/2018	02/08/2018	Details
Sodium chloroacetate	223-498-3	3926-62-3	Reproductive toxicity (pre-natal developmental toxicity)	14/10/2011	28/11/2011	Details
Sodium chloroacetate	223-498-3	3926-62-3	Reproductive toxicity (two-generation reproductive toxicity)	16/06/2011	01/08/2011	Details
Nonane-1,9-diol	223-517-5	3937-56-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral	05/07/2018 05/07/2018	20/08/2018 20/08/2018	Details
Nonane-1,9-diol	223-517-5	3937-56-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral	16/12/2020 16/12/2020	01/02/2021 01/02/2021	Details
2,3-epoxypropyl isopropyl ether	223-672-9	4016-14-2	Genetic toxicity in vivo	19/10/2020	03/12/2020	Details
3,6,9,12-tetraazatetradecamethylenediamine	223-775-9	4067-16-7	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7). Reproductive toxicity (pre-natal developmental toxicity)	22/11/2017 22/11/2017	08/01/2018 08/01/2018	Details
3,6,9,12-tetraazatetradecamethylenediamine	223-775-9	4067-16-7	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	28/02/2011 28/02/2011	14/04/2011 14/04/2011	Details
2,2'-oxybis[5,5-dimethyl-1,3,2-dioxaphosphorinane] 2,2'-disulphide	223-829-1	4090-51-1	Sub-chronic toxicity (90-day): oral	16/06/2022	01/08/2022	Details
Sodium p-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzenesulphonate	223-989-2	4156-21-2	Reproductive toxicity (pre-natal developmental toxicity)	03/04/2023	22/05/2023	Details
Sodium p-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzenesulphonate	223-989-2	4156-21-2	Sub-chronic toxicity (90-day): oral	29/04/2014	13/06/2014	Details
2,2-dimethylpropane-1,3-diyl dibenzoate	224-081-9	4196-89-8	Reproductive toxicity (pre-natal developmental toxicity)	29/02/2016	14/04/2016	Details
2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate	224-116-8	4203-89-8	Genetic toxicity in vivo	23/03/2020	07/05/2020	Details
3,3'-oxybis(ethyleneoxy)bis(propylamine)	224-207-2	4246-51-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2021 18/02/2021	05/04/2021 05/04/2021	Details
methylsilanetriyl triacetate	224-221-9	4253-34-3	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with [Trimethoxy(methyl)silane] (EC 214-685-0)	16/03/2015	30/04/2015	Details
methylsilanetriyl triacetate	224-221-9	4253-34-3	Sub-chronic toxicity (90-day): oral\|\|Note: testing proposed with [triethoxy(methyl)silane] (CAS no. 2031-67-6)	03/10/2023	17/11/2023	Details
Di-tert-butyl trisulphide	224-226-6	4253-90-1	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	01/03/2023 01/03/2023 01/03/2023	17/04/2023 17/04/2023 17/04/2023	Details
Di-tert-butyl trisulphide	224-226-6	4253-90-1	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate)	224-235-5	4259-15-8	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"	04/10/2018 04/10/2018 04/10/2018	19/11/2018 19/11/2018 19/11/2018	Details
zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate)	224-235-5	4259-15-8	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with the substance and with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with the substance and with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
2,2,4,4,6,8,8-heptamethylnonane	224-506-8	4390-04-9	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with two substances in a grouping approach: Icosane (EC 204-015-1) and Hydrocarbons, C14-C19, iso-alkanes, cyclics; aromatics <2% (920-114-2)	02/11/2018	17/12/2018	Details
Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane	224-506-8	4390-04-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details

Ukazujem 401 - 600 z 1 996 výsledkov.

Export in: