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Preskoč na obsah

Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Allyl (cyclohexyloxy)acetate 272-657-3 68901-15-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/08/2018
10/08/2018
24/09/2018
24/09/2018
Allylamine 203-463-9 107-11-9 Genetic toxicity in vivo 09/09/2013 24/10/2013
Aluminium oxide 215-691-6 1344-28-1 Genetic toxicity in vivo || Note: Testing proposal for two in vivo studies is based on concern identified by the registrant. Testing proposed with Aluminium oxide nanoscale material. 28/02/2018 16/04/2018
Aluminium tris(dialkylphosphinate) - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
23/06/2011
23/06/2011
08/08/2011
08/08/2011
Aluminum triformate 230-898-1 7360-53-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity study (90-day): oral
21/01/2011
21/01/2011
21/01/2011
07/03/2011
07/03/2011
07/03/2011
Aluminum, benzoate C16-18-fatty acids complexes 303-385-6 94166-87-7 Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015
Amides, C16-C18 (even numbered) 931-695-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Amides, C16-C18 (even) , N,N'-ethylenebis 931-299-4 - Sub-chronic toxicity (90-day): oral 16/08/2011 30/09/2011
Amides, C18 (unsaturated) - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Amides, C22 (unsaturated) - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Amides, C8-18(even-numbered) and C18(unsatd.), N-(2-hydroxypropyl) - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Amides, fatty acids C18 unsat, reaction products with polyethylene amines 629-735-0 1226892-50-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Amides, Fatty acids C18 unsaturated, reaction products with tetraethylenepentamine 630-459-8 1225197-81-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Amines, C16-22-alkyl 268-215-4 68037-92-3 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014
Amines, N-tallow alkyltrimethylenedi-, propoxylated 614-637-2 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Amines, polyethylenepoly- 268-626-9 68131-73-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 22/11/2017 08/01/2018
Amines, polyethylenepoly- 268-626-9 68131-73-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
28/02/2011
28/02/2011
14/04/2011
14/04/2011
Amines, polyethylenepoly- 268-626-9 68131-73-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
Amines, polyethylenepoly-, tetraethylenepentamine fraction 292-587-7 90640-66-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/11/2015 16/12/2015
Amines, polyethylenepoly-, tetraethylenepentamine fraction 292-587-7 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with TETA (CAS 90640-67-8) and HEPA (68121-73-7)
Reproductive toxicity (pre-natal developmental toxicity )
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Amines, polyethylenepoly-, triethylenetetramine fraction 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/11/2017
22/11/2017
08/01/2018
08/01/2018


Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched 292-588-2 90640-66-7 Reproductive toxicity (two-generation reproductive toxicity) 05/04/2011 20/05/2011
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Amines, tallow alkyl, dodecylbenzenesulfonates 268-766-0 68139-94-6
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/11/2015
30/11/2015
30/11/2015
14/01/2016
14/01/2016
14/01/2016
Aminoiminomethanesulphinic acid 217-157-8 1758-73-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Amorphous glass product formed from the melting and fiberisation of dipotassium oxide, oxo(oxoalumanyloxy)alumane and dioxosilane 931-219-8 - Sub-chronic toxicity (90 day): inhalation 24/05/2013 08/07/2013
Anisole 202-876-1 100-66-3 Reproductive toxicity (pre-natal developmental toxicity) 15/04/2014 30/05/2014
arbonohydrazide 207-837-2 497-18-7
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Aromatic hydrocarbons, C10-13, reaction products with branched nonene, sulfonated, sodium salts 800-660-7 1258274-08-6 Reproductive toxicity (pre-natal developmental toxicity) 23/01/2015 09/03/2015
Ashes (residues), nonhazardous municipal solid waste 937-417-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/08/2012
17/08/2012
01/10/2012
01/10/2012
Ashes (residues), plant 297-049-5 93333-79-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Ashes (residues), plant 297-049-5 93333-79-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2011
16/05/2011
16/05/2011
30/06/2011
30/06/2011
30/06/2011
Ashes from fluidized Bed combustion coal fired Power stations with and without co-combustion of secondary fuels (biomass,other fuels - to be verified in view of ecotoxicological and toxicological tests) 931-257-5 - Reproductive toxicity (pre-natal developmental toxicity) 05/04/2011 20/05/2011
ASPHALT 232-490-9 8052-42-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/05/2016
31/05/2016
15/07/2016
15/07/2016
Asphalt 232-490-9 8052-42-4 Reproductive toxicity (extended one-generation reproductive toxicity study)

[note whilst the registrant has selected the drop down of a RaX TPE – it is not a RaX TPE – registered substance is being tested]”
25/06/2019 09/08/2019
Asphalt, oxidized 265-196-4 64742-93-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Asphalt, oxidized 265-196-4 64742-93-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2019 09/08/2019
Asphalt, oxidized 265-196-4 64742-93-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
18/02/2013
18/02/2013
04/04/2013
04/04/2013
Aziridine 205-793-9 151-56-4 Long-term toxicity to fish 26/01/2011 14/03/2011
Barium carbonate 208-167-3 513-77-9 Long-term toxicity to fish 29/04/2011 14/06/2011
Barium carbonate 208-167-3 513-77-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/12/2011
16/12/2011
30/01/2012
30/01/2012
Barium chloride 233-788-1 10361-37-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Barium chloride 233-788-1 10361-37-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/04/2011
29/04/2011
29/04/2011
14/06/2011
14/06/2011
14/06/2011
Barium diboron tetraoxide 237-222-4 13701-59-2 Reproductive toxicity (two-generation reproductive toxicity) 16/05/2014 30/06/2014
Barium hydroxide 241-234-5 17194-00-2 Long-term toxicity to fish 29/04/2011 14/06/2011
Barium hydroxide 241-234-5 17194-00-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/12/2011
16/12/2011
30/01/2012
30/01/2012
Barium sulfate 231-784-4 7727-43-7 Long-term toxicity to fish 29/04/2011 14/06/2011
barium titanium trioxide 234-975-0 12047-27-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
17/04/2015
17/04/2015
04/06/2015
04/06/2015
Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene 270-128-1 68411-46-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/10/2017 11/12/2017
Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene 270-128-1 68411-46-1
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity study (90-day): oral
05/04/2011
05/04/2011
20/05/2011
20/05/2011
Benzenamine, N-phenyl-, reaction products with styrene and 2,4,4-trimethylpentene 272-940-1 68921-45-9
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the smallest aryl- and alkyl-substituted materials
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with the smallest aryl- and alkyl-substituted materials
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Benzene, 1,1'-oxybis-, tetrapropylene derivatives, sulfonated, sodium salts 601-601-6 119345-04-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity) with the Rabbit
27/05/2019
27/05/2019
11/07/2019
11/07/2019
Benzene, diethenyl- and Benzene, ethenylethyl- 910-757-7 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/08/2019
16/08/2019
30/09/2019
30/09/2019
Benzene-1,2,4-tricarboxylic acid 1,2-anhydride, oligomeric reaction products with ethane-1,2-diol and glycerol 500-199-9 68183-39-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
Benzoic acid, 2-hydroxy-, mono-C14-18-alkyl derivs., calcium salts (2:1) 931-276-9 - Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Benzoic acid, 2-hydroxy-, mono-C>13-alkyl derivs., calcium salts (2:1) 281-018-8 83846-43-9 Sub-chronic toxicity (90-day): oral 18/06/2018 02/08/2018
Benzophenone-3,3':4,4'-tetracarboxylic dianhydride 219-348-1 2421-28-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Benzotriazole 202-394-1 95-14-7 Reproductive toxicity (pre-natal developmental toxicity) 22/10/2013 05/12/2013
benzyl 3-isobutyryloxy-1-isopropyl-2,2-dimethylpropyl phthalate 240-920-1 16883-83-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/06/2011
16/06/2011
01/08/2011
01/08/2011
benzyl butyl cis-cyclohexane-1,2-dicarboxylate 701-279-8 1931129-39-3
Long-term toxicity to fish || Note: Link to the registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5
Sub-chronic toxicity (90-day): oral || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5
10/12/2018
10/12/2018
10/12/2018
24/01/2019
24/01/2019
24/01/2019
Benzyldimethylamine 203-149-1 103-83-3 Reproductive toxicity (pre-natal developmental toxicity) 15/09/2011 31/10/2011
Benzyltoluene 248-654-8 27776-01-8 Long-term toxicity to fish (OECD 210) 25/06/2019 09/08/2019
Benzyltoluene 248-654-8 27776-01-8 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2014 04/04/2014
benzyltrimethylammonium chloride 200-300-3 56-93-9 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2014 17/03/2014
Biphenyl 202-163-5 92-52-4 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2018 19/03/2018
Biphenyl-4,4'-diol 202-200-5 92-88-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/04/2019
26/04/2019
10/06/2019
10/06/2019
Biphenyl-4,4'-diol 202-200-5 92-88-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Bis(1,2,2,6,6-pentamethyl-4-piperidyl) [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]butylmalonate 264-513-3 63843-89-0 Genetic toxicity in vivo 29/04/2014 13/06/2014
Bis(2,3-epoxypropyl) terephthalate 230-565-0 7195-44-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2012
16/05/2012
16/05/2012
02/07/2012
02/07/2012
02/07/2012
Bis(2,4,4-trimethylpentyl)phosphinic acid 280-445-7 83411-71-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2014
29/04/2014
13/06/2014
13/06/2014
bis(2,4-dichlorobenzoyl) peroxide 205-094-9 133-14-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
05/05/2014
05/05/2014
bis(2-(2-butoxyethoxy)ethoxy)methane 205-598-9 143-29-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Bis(2-(2-butoxyethoxy)ethoxy)methane 205-598-9 143-29-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Bis(2-butoxyethyl) adipate 205-466-0 141-18-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Bis(2-chloroethoxy)methane 203-920-2 111-91-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
14/02/2011
14/02/2011
31/03/2011
31/03/2011
Bis(2-chloroethoxy)methane 1,15-dichloro-3,5,8,11,13-penta-oxa pentadecane 1-(2-chloroethoxy)-2-(2-chloroethoxymethoxy)ethane 940-783-4 -
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (two-generation reproductive toxicity) // Note: test to be performed with analogues substance 1-chloro-2-[(2-chloroethoxy)methoxy]ethane (EC 203-920-2 )
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
Bis(2-chloroethyl) 3,3'-[(2,5-dimethyl-p-phenylene)bis[iminocarbonyl(2-hydroxy-1,3-naphthylene)azo]]di-p-toluate 269-507-4 68259-05-2 Sub-chronic toxicity (90 day): inhalation || Note: Testing proposal is based on concern identified by the registrant 24/07/2019 09/09/2019
bis(2-dimethylaminoethyl)(methyl)amine 221-201-1 3030-47-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
Bis(2-ethylhexyl) fumarate 205-448-2 141-02-6
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
14/02/2011
14/02/2011
14/02/2011
31/03/2011
31/03/2011
31/03/2011
Bis(2-ethylhexyl) peroxydicarbonate 240-282-4 16111-62-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
Bis(2-ethylhexyl) tetrabromophthalate 247-426-5 26040-51-7 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014
bis(3,5,5-trimethylhexanoyl) peroxide 223-356-0 3851-87-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
bis(4-(1,1,3,3-tetramethylbutyl)phenyl)amine 239-816-9 15721-78-5
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
18/02/2014
04/04/2014
04/04/2014
04/04/2014
Bis(4-chlorophenyl) sulphone 201-247-9 80-07-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
bis(4-chlorophenyl) sulphone 201-247-9 80-07-9
Bioaccumulation: terrestrial
Reproductive toxicity (pre-natal developmental toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
bis(4-tert-butylcyclohexyl) peroxydicarbonate 239-557-1 15520-11-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Bis(dibutyldithiocarbamato-S,S')copper 237-695-7 13927-71-4 Long-term toxicity to fish 22/06/2017 07/08/2017
Bis(nonylphenyl)amine / Reaction products of Benzeneamine, N-phenyl- with nonene (branched) - -
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
28/02/2011
28/02/2011
14/04/2011
14/04/2011
bis(piperidinothiocarbonyl) hexasulphide 213-537-2 971-15-3 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 16/02/2015 02/04/2015
bis(piperidinothiocarbonyl) hexasulphide 213-537-2 971-15-3 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2014 13/06/2014
bis(α,α-dimethylbenzyl) peroxide 201-279-3 80-43-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
01/08/2011
01/08/2011
Bis(α,α-dimethylbenzyl) peroxide 201-279-3 80-43-3 Reproductive toxicity (pre-natal developmental toxicity 20/10/2016 05/12/2016
Bis[2-[2-(1-methylethyl)-3-oxazolidinyl]ethyl] hexan-1,2-diylbiscarbamate 261-879-6 59719-67-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate   940-272-6 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity
Sub-chronic toxicity (90-day): oral
01/09/2017
01/09/2017
01/09/2017
16/10/2017
16/10/2017
16/10/2017
Bisdecanoyl peroxide 212-092-1 762-12-9 Long-term toxicity to fish 27/09/2017 13/11/2017
Bisisobutyryl peroxide 222-340-0 3437-84-1
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
04/04/2014
04/04/2014
04/04/2014
19/05/2014
19/05/2014
19/05/2014
Bismuth 231-177-4 7440-69-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
30/05/2011
30/05/2011
bismuth citrate 212-390-1 813-93-4
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
bismuth hydroxide nitrate oxide 215-136-8 1304-85-4 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014
bismuth oxide salicylate 238-953-1 14882-18-9 Sub-chronic toxicity (90 day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8) 18/09/2014 03/11/2014
Bismuth trinitrate 233-791-8 10361-44-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8)
20/09/2013
20/09/2013
04/11/2013
04/11/2013
Boric acid (H3BO3), reaction products with ethanolamine 302-207-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/01/2012
16/01/2012
16/01/2012
01/03/2012
01/03/2012
01/03/2012
boron orthophosphate - 13308-51-5 Reproductive toxicity (pre-natal developmental toxicity) 30/06/2016 15/08/2016
Boron trifluoride 231-569-5 - Genetic toxicity in vivo 01/07/2011 15/08/2011
branched-nonyl 3,5,5 trimethylhexanoate 701-133-3 - Sub-chronic toxicity (90-day): oral || Note: previous EC no 609-993-0 21/05/2018 05/07/2018
Bumetrizole 223-445-4 3896-11-5 Bioaccumulation aquatic / sediment 18/06/2018 02/08/2018
butan-2-one O,O',O''-(vinylsilylidyne)trioxime 218-747-8 2224-33-1 Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Butan-2-one O,O',O''-(methylsilylidyne)trioxime (CAS 22984-54-9).
25/06/2015 10/08/2015
Butanoic acid, 4-amino-4-oxo-2(or 3)-sulfo-,N-(C16-C18 (even numbered), C18 unsaturated alkyl)), disodium salts 939-691-7 - Reproductive toxicity (pre-natal developmental toxicity) 17/09/2019 01/11/2019
Butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium(trialkyloxy)titanium phosphate 401-100-0 - Sub-chronic toxicity (90-day): oral 27/05/2019 11/07/2019
Butyl glycollate 230-991-7 7397-62-8 Sub-chronic toxicity (90-day): oral 15/04/2011 30/05/2011
Butyronitrile 203-700-6 109-74-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons 700-762-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with an analogue substance.
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with an analogue substance.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with an analogue substance.
01/10/2018
01/10/2018
01/10/2018
15/11/2018
15/11/2018
15/11/2018
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons 700-762-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
25/09/2012
25/09/2012
12/11/2012
12/11/2012
C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters 701-257-8 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Sulfonic acids, C10-C21-alkane, Ph-esters (EC 293-728-5) 10/08/2018 24/09/2018
C16-(branched), C20-(branched) and C24-(branched)-alkanes 700-992-1 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/02/2018
28/02/2018
28/02/2018
16/04/2018
16/04/2018
16/04/2018
C20-C22 (even numbered, linear and branched) and C24 (branched) alkenes 700-497-0 -
Reproductive toxicity (two-generation reproductive toxicity and developmental toxicity)
Sub-chronic toxicity (90-day): oral
19/11/2010
25/06/2012
03/01/2011
09/08/2012
C26-28 (even numbered) α-alkenes 934-268-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
18/06/2012
18/06/2012
18/06/2012
02/08/2012
02/08/2012
02/08/2012
C8-C26 branched and linear hydrocarbons - Distillates 481-740-5 848301-67-7 Bioaccumulation aquatic / sediment 11/05/2010 25/06/2010
calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalenesulphonate) 939-717-7 - Sub-chronic toxicity (90-day): oral 02/06/2014 17/07/2014
Calcium carbonate 207-439-9 471-34-1 Sub-chronic toxicity (90 day): inhalation 15/07/2011 29/08/2011
Calcium cyanamide 205-861-8 156-62-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
calcium cyanamide 205-861-8 156-62-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Calcium dihydroxide precipitated with carbon dioxide during sugar juice purification 932-124-4 - Sub-chronic toxicity (90 day): inhalation 01/07/2011 15/08/2011
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated 941-216-3 -
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distillation Residue 941-212-1 -
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distilled - -
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Cashew, nutshell liq. 232-355-4 8007-24-7
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
31/10/2011
Cashew, nutshell liq., oligomeric reaction products with 1-chloro-2,3-epoxypropane - 68413-24-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
cerium trinitrate 233-297-2 10108-73-3 Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015
Chloroacetic acid 201-178-4 79-11-8 Reproductive toxicity (pre-natal developmental toxicity) 14/10/2011 28/11/2011
Chloroacetic acid 201-178-4 79-11-8 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011
chlorodimethylvinylsilane 217-007-1 1719-58-0 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethylsilanol (CAS 1066-40-6) 12/12/2014 26/01/2015
Chloroethane 200-830-5 75-00-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
10/03/2017
10/03/2017
25/04/2017
25/04/2017
Citral 226-394-6 5392-40-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Cobalt 231-158-0 7440-48-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt (II) dinitrate 233-402-1 10141-05-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt (II) sulphate 233-334-2 10124-43-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity) ; after obtaining results of the 90-day subchronic toxicity study
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt bis(2-ethylhexanoate) 205-250-6 136-52-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt dichloride 231-589-4 7646-79-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
cobalt dichloride 231-589-4 7646-79-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/07/2016
18/07/2016
01/09/2016
01/09/2016


Cobalt dihydroxide 244-166-4 21041-93-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt hydroxide oxide 234-614-7 12016-80-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt oxalate 212-409-3 814-89-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt oxide 215-154-6 1307-96-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt sulphide 215-273-3 1317-42-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt(2+) propionate 216-333-1 1560-69-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt(II) 4-oxopent-2-en-2-olate 237-855-6 14024-48-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt(II) carbonate 208-169-4 513-79-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt(II) diacetate 200-755-8 71-48-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt, borate neodecanoate complexes 270-601-2 68457-13-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Coconut oil, reaction products with polyethylene glycol and trimethylolpropane 640-964-5 -
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Condensates (petroleum), vacuum tower 265-049-4 64741-49-7 Reproductive toxicity (two-generation reproductive toxicity) 15/09/2011 31/10/2011
Condensation product of N-C12-C18- alkylpropane-1,3-diamine, N-(3- aminopropyl)-N'-C12-C18- alkylpropane-1,3-diamine and formic acid 641-088-6 -
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
16/08/2011
30/09/2011
30/09/2011
30/09/2011
Condensation products of dimerised fatty acids, C18-unsaturated, with N,N-dimethyl-1,3-propanediamine and 1,3-propanediamine 605-296-0 162627-17-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): oral
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
Condensation products of triethanolamine with addition products of fatty acids, C18 (unsaturated) alkyl with maleic anhydride - -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/03/2017
10/03/2017
10/03/2017
25/04/2017
25/04/2017
25/04/2017
Copolymer of acetonoxime and 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate 600-028-9 1001254-87-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): dermal
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Copolymer of benzenamine and formaldehyde, hydrogenated 603-894-6 135108-88-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
Copper (2+), bis [N-{amino (imino-KN) methyl} urea-KO]-, nitrate (1:2) 800-038-5 1071838-81-7 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/01/2015 09/03/2015
Copper hydroxide nitrate 439-590-3 12158-75-7 Reproductive toxicity (pre-natal developmental toxicity) 03/11/2011 19/12/2011
Coupling reaction products of diazotized 2-amino-6-[(2-substituted ethyl)sulfonyl]naphthalene-1-subsituted acid with 4-({4-chloro-6-[ethyl(3-{[2-(substituted oxy)ethyl]sulfonyl}phenyl)amino]-heteromonocycl-2-yl}amino)-5-hydroxynaphthalene-2,7-disubstituted acid and their sodium and potassium salts - - 7.6.2 Mammalian erythrocyte micronucleus test according to OECD 474 03/12/2010 17/01/2011
Cyclohexane-1,4-dicarboxylic acid 214-068-6 1076-97-7 Reproductive toxicity (pre-natal developmental toxicity) 27/11/2013 10/01/2014
Cyclohexane-1,4-diyldimethanol 203-268-9 105-08-8 OECD Guideline 414 (Prenatal Developmental Toxicity Study) 19/11/2010 03/01/2011
Cyclohexyldimethoxymethylsilane 402-140-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/01/2012
16/01/2012
16/01/2012
01/03/2012
01/03/2012
01/03/2012
Cyclohexylidenebis[tert-butyl] peroxide 221-111-2 3006-86-8 Sub-chronic toxicity (90-day): oral 21/03/2014 05/05/2014
D-glucopyranose, oligomeric, C10-16 glycosides (even numbered), carboxymethyl ethers, sodium salts 609-542-8 383178-66-3 Reproductive toxicity (pre-natal developmental toxicity) 30/11/2015 14/01/2016
D-glucopyranose, oligomers, xylityl glycosides and 1,4 anhydro D-xylitol and D-xylitol 446-990-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
23/01/2015
23/01/2015
09/03/2015
09/03/2015
d-Glucose, ether with glycerol 309-496-6 100402-60-6 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014
Dec-1-ene 212-819-2 872-05-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Decahydronaphthalene 202-046-9 91-17-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
decahydronaphthalene 202-046-9 91-17-8 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011
Decamethylcyclopentasiloxane 208-764-9 541-02-6 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017
Decamethylenediamine 211-471-9 646-25-3 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014
decamethyltetrasiloxane 205-491-7 141-62-8 Reproductive toxicity (pre-natal developmental toxicity) 16/10/2014 01/12/2014
Decane 204-686-4 124-18-5 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012
Decene 246-870-7 25339-53-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Decene, hydroformylation products, high boiling 935-454-7 -
Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8)
Sub-chronic toxicity (90-day): oral // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8)
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Destillation fraction of chlorosilanes 700-717-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation 
16/05/2012
16/05/2012
02/07/2012
02/07/2012
di(morpholin-4-yl) disulphide 203-103-0 103-34-4
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
29/04/2011
29/04/2011
14/06/2011
14/06/2011
di-tert-butyl 1,1,4,4-tetramethyltetramethylene diperoxide 201-128-1 78-63-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/10/2011
14/10/2011
28/11/2011
28/11/2011
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide 229-782-3 6731-36-8 Reproductive toxicity (pre-natal developmental toxicity) 01/07/2011 15/08/2011
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide 229-782-3 6731-36-8 Bioaccumulation aquatic / sediment 25/06/2019 09/08/2019
Di-tert-butyl peroxide 203-733-6 110-05-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/07/2011
01/07/2011
01/07/2011
15/08/2011
15/08/2011
15/08/2011
Diammonium dihydrogen ethylenediaminetetraacetate 244-063-4 20824-56-0 Sub-chronic toxicity (90 day): inhalation 29/07/2011 12/09/2011
Diammonium hexachloroplatinate 240-973-0 16919-58-7 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/04/2018 07/06/2018
diammonium hexanitratocerate 240-827-6 16774-21-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cerium (III) nitrate (CAS 10294-41-4) 20/05/2015 06/07/2015
Dibenzoyl peroxide 202-327-6 94-36-0 Reproductive toxicity (pre-natal developmental toxicity) 16/06/2011 01/08/2011
Dibismuth trioxide 215-134-7 1304-76-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2011
29/04/2011
14/06/2011
14/06/2011
Dibutyl fumarate 203-327-9 105-75-9 Long-term toxicity to fish 16/05/2011 30/06/2011
dichloro(3-chloropropyl)methylsilane 232-136-3 7787-93-1 Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6, CAS 5089-70-3) 16/10/2014 01/12/2014
dichloro(diphenyl)silane 201-251-0 80-10-4
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9)
Sub-chronic toxicity (90-day): oral
Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
Dichloro(methyl)(phenyl)silane 205-746-2 149-74-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethoxy(phenyl)silane (EC 221-066-9, CAS 2996-92-1) 04/04/2014 19/05/2014
dichlorocyclohexylmethylsilane 226-956-0 5578-42-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [dicyclopentyldimethoxysilane] (CAS 126990-35-0) 16/03/2015 30/04/2015
Dichloromethylbenzene 249-854-8 29797-40-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 22/06/2017 07/08/2017
Dichloromethylbenzene 249-854-8 29797-40-8 Reproductive toxicity (pre-natal developmental toxicity) 15/09/2011 31/10/2011
Dichloromethylbenzene 249-854-8 29797-40-8 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2014 17/03/2014
Dicyclohexylamine 202-980-7 101-83-7
Genetic toxicity in vivo (mammalian bone marrow chromosome aberration test)
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/03/2011
15/03/2011
15/03/2011
15/03/2011
29/04/2011
29/04/2011
29/04/2011
29/04/2011
Dicyclopentyldimethoxysilane 404-370-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2011
16/12/2011
16/12/2011
30/01/2012
30/01/2012
30/01/2012
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate 220-482-8 2781-11-5 Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020 12/03/2020
Diethyl carbonate 203-311-1 105-58-8 Genetic toxicity in vivo 18/02/2014 04/04/2014
Diethyl ether 200-467-2 60-29-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 02/11/2018 17/12/2018



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