Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Zobrazuje sa 201 - 400 z 2 011 výsledkov.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
2-Oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene derivs., (4E)-	939-401-9	1469983-41-2	Long-term toxicity to fish \|\|Note: testing proposed with 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs (EC no. 308-760-8)	15/07/2022	29/08/2022	Details
3-{[3-(C10-16-oxy)propyl]amino}propan-1-aminium acetate	941-152-6	-	Sub-chronic toxicity (90-day): oral\|\|Note: testing proposed with 1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC: 931-295-2)	15/07/2022	29/08/2022	Details
Geraniol	203-377-1	106-24-1	Reproductive toxicity (pre-natal developmental toxicity)	15/07/2022	29/08/2022	Details
N-{3-[C12-14-(even numbered)-alkyloxy]propyl}propane-1,3-diamine	701-437-6	-	Sub-chronic toxicity (90-day): oral\|\| Note: testing proposed with [1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC no 931-295-2)	15/07/2022	29/08/2022	Details
1,1'-methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol and oligomerization reaction products of oxydipropanol	701-041-3	-	Sub-chronic toxicity (90 day): inhalation Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	16/06/2022 16/06/2022 16/06/2022	01/08/2022 01/08/2022 01/08/2022	Details
4,4'-Isopropylidenediphenol, ethoxylated	500-082-2	32492-61-8	Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	16/06/2022 16/06/2022 16/06/2022	01/08/2022 01/08/2022 01/08/2022	Details
Amino functional alkoxysilanes	701-410-9	-	Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	16/06/2022 16/06/2022 16/06/2022	01/08/2022 01/08/2022 01/08/2022	Details
N1,N3‐bis(3‐methylphenyl)‐5‐[(3‐methylphenyl)sulfamoyl]benzene‐1,3‐dicarboxamide	951-483-8	2375645-78-4	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	16/06/2022 16/06/2022 16/06/2022	01/08/2022 01/08/2022 01/08/2022	Details
1,1,1,3,3,3-hexamethyldisilazane	213-668-5	999-97-3	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with Hydroxytrimethylsilane (EC no. 213-914-1) Reproductive toxicity (pre-natal developmental toxicity)\|\| Note: testing proposed with Hydroxytrimethylsilane (EC no. 213-914-1)	16/06/2022 16/06/2022	01/08/2022 01/08/2022	Details
Reaction products of adipic acid and 2,3-epoxypropyl C10-(branched) alkanoate	825-846-5	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	16/06/2022 16/06/2022	01/08/2022 01/08/2022	Details
Thymol	201-944-8	89-83-8	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity)	16/06/2022 16/06/2022	01/08/2022 01/08/2022	Details
Vanadium dioxide	234-841-1	12036-21-4	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: : testing proposed with Sodium metavanadate (EC no. 237-272-7) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with Sodium metavanadate (EC no. 237-272-7)	16/06/2022 16/06/2022	01/08/2022 01/08/2022	Details
1,1'-Methylenebis(4-isocyanatobenzene) and 1,1'-methylenebis(4-isocyanatobenzene) homopolymer and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propane-1,2-diol	701-393-8	-	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	16/06/2022	01/08/2022	Details
2,2'-oxybis[5,5-dimethyl-1,3,2-dioxaphosphorinane] 2,2'-disulphide	223-829-1	4090-51-1	Sub-chronic toxicity (90-day): oral	16/06/2022	01/08/2022	Details
4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol	701-072-2	-	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no: 202-966-0)	16/06/2022	01/08/2022	Details
4,4'-Methylenediphenyl diisocyanate, oligomers	500-040-3	25686-28-6	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	16/06/2022	01/08/2022	Details
4,4'-sulphonyldiphenol	201-250-5	80-09-1	Long-term toxicity to fish	16/06/2022	01/08/2022	Details
Naphthalene-2,6-dicarboxylic acid	214-527-0	1141-38-4	Reproductive toxicity (pre-natal developmental toxicity)	16/06/2022	01/08/2022	Details
Reaction mass of 4,4'-methylenediphenyl diisocyanate and o-(p-isocyanatobenzyl)phenyl isocyanate / methylene diphenyl diisocyanate	905-806-4	-	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	16/06/2022	01/08/2022	Details
Reaction product of 4,4'-methylenediphenyl diisocyanate, Octylamine and Hexamethylenediamine	924-670-7	-	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3)	16/06/2022	01/08/2022	Details
tert-dodecanethiol	246-619-1	25103-58-6	Long-term toxicity to fish	16/06/2022	01/08/2022	Details
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate	411-700-4	140921-24-0	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022 10/05/2022	27/06/2022 27/06/2022 27/06/2022	Details
Diphosphoric acid, compd. with piperazine (1:1)	457-330-7	66034-17-1	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022 10/05/2022	27/06/2022 27/06/2022 27/06/2022	Details
1,2-dimethylimidazole	217-101-2	1739-84-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
1,3-dimethylimidazolidin-2-one	201-304-8	80-73-9	Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
4-morpholinecarbaldehyde	224-518-3	4394-85-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
Diamminediisocyanatozinc	401-610-3	122012-52-6	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
Divanadium pentaoxide	215-239-8	1314-62-1	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with sodium metavanadate (EC no. 237-272-7) Reproductive toxicity (pre-natal developmental toxicity)\|\| Note: testing proposed with sodium metavanadate (EC no. 237-272-7)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
Ethyl 4-dimethylaminobenzoate	233-634-3	10287-53-3	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane	224-506-8	4390-04-9	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
N,N-dimethyl-alkyl-1-amines, reaction products with alkali hydroxide and chloroacetic acid	939-682-8	-	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
Oleic acid, compound with (Z)-N-octadec-9-enylpropane-1,3-diamine (2:1)	251-846-4	34140-91-5	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
Propene	204-062-1	115-07-1	Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with ethylene (EC no. 200-815-3) Reproductive toxicity (extended one-generation reproductive toxicity study)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
1,1,3,3-tetramethylbutyl 2-ethylperoxyhexanoate	244-894-2	22288-43-3	Genetic toxicity in vivo	10/05/2022	27/06/2022	Details
5-sulphosalicylic acid	202-555-6	97-05-2	Genetic toxicity in vivo	10/05/2022	27/06/2022	Details
Amino functional alkoxysilanes	701-408-8	-	Genetic toxicity in vivo	10/05/2022	27/06/2022	Details
bis(α,α-dimethylbenzyl) peroxide	201-279-3	80-43-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	10/05/2022	27/06/2022	Details
Dibutyl hydrogen phosphate	203-509-8	107-66-4	Long-term toxicity to fish	10/05/2022	27/06/2022	Details
Ethyl 4-[[(methylphenylamino)methylene]amino]benzoate	260-976-0	57834-33-0	Genetic toxicity in vivo	10/05/2022	27/06/2022	Details
m-cresol	203-577-9	108-39-4	Long-term toxicity to fish\|\| Note: testing proposed with p-cresol (EC no. 203-398-6)	10/05/2022	27/06/2022	Details
o-cresol	202-423-8	95-48-7	Long-term toxicity to fish\|\|Note: testing proposed with p-cresol (EC no. 203-398-6)	10/05/2022	27/06/2022	Details
Octanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-1,3-propanediol and 3-(triethoxysilyl)-1-propanethiol	485-270-1	-	Genetic toxicity in vivo	10/05/2022	27/06/2022	Details
p-cresol	203-398-6	106-44-5	Long-term toxicity to fish	10/05/2022	27/06/2022	Details
plastic, waste, pyrolized, fractionation bottoms (raw diesel)	942-177-5	-	Genetic toxicity in vivo	10/05/2022	27/06/2022	Details
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt	939-650-3	-	Sub-chronic toxicity (90-day): oral	10/05/2022	27/06/2022	Details
reaction products of 1,4-butanediol with 1,3-chloro-2,3-epoxypropane, esters with prop-2-enoic acid	701-230-0	-	Long-term toxicity to fish	10/05/2022	27/06/2022	Details
Tetrasodium 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[(6-sulphonato-2-naphthyl)azo]naphthalene-2-sulphonate]	249-171-5	28706-25-4	Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022	27/06/2022	Details
Tridecan-1-ol	203-998-8	112-70-9	Reproductive toxicity (extended one-generation reproductive toxicity study)	10/05/2022	27/06/2022	Details
Fatty acids, C8-10, C12-18-alkyl esters	306-082-7	95912-86-0	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	01/04/2022 01/04/2022 01/04/2022	16/05/2022 16/05/2022 16/05/2022	Details
Bis(2-ethylhexyl) adipate	203-090-1	103-23-1	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study)	01/04/2022 01/04/2022	16/05/2022 16/05/2022	Details
Octadecanoic acid, 12-hydroxy-, reaction products with decanoic acid and ethylenediamine	907-495-0	-	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study)	01/04/2022 01/04/2022	16/05/2022 16/05/2022	Details
Vanadium oxide sulphate	248-652-7	27774-13-6	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with sodium metavanadate (EC 237-272-7) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with sodium metavanadate (EC 237-272-7)	01/04/2022 01/04/2022	16/05/2022 16/05/2022	Details
1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol	701-124-4	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	01/04/2022	16/05/2022	Details
1,1'-methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with butane-1,3-diol, 2,2'-oxydiethanol and propane-1,2-diol	701-173-1	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0)	01/04/2022	16/05/2022	Details
1,3-Butanediol, reaction products with 1,1'-methylenebis[4-isocyanatobenzene], propylene glycol and tripropylene glycol	941-496-7	1689576-89-3	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0)	01/04/2022	16/05/2022	Details
1-isocyanato-2(or 4)-(4-isocyanatobenzyl)benzene and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propylene glycol	701-029-8	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0)	01/04/2022	16/05/2022	Details
2,2'-methylenediphenyl diisocyanate	219-799-4	2536-05-2	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	01/04/2022	16/05/2022	Details
2,2,2',2'-Tetrakis(hydroxymethyl)-3,3'-oxydipropan-1-ol	204-794-1	126-58-9	Reproductive toxicity (extended one-generation reproductive toxicity study)	01/04/2022	16/05/2022	Details
2-(2H-Benzotriazol-2-yl)-6-(1-methyl-1-phenylethyl)-4-(1,1,3,3-tetramethylbutyl)phenol	422-600-5	73936-91-1	Bioaccumulation aquatic / sediment	01/04/2022	16/05/2022	Details
2-methylpentane-2,4-diol	203-489-0	107-41-5	Long-term toxicity to fish	01/04/2022	16/05/2022	Details
Benzenamine, 4,4'-methylenebis[3-chloro-2,6-diethyl-	402-130-7	106246-33-7	Reproductive toxicity (pre-natal developmental toxicity)	01/04/2022	16/05/2022	Details
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide	229-782-3	6731-36-8	Bioaccumulation aquatic / sediment	01/04/2022	16/05/2022	Details
Formaldehyde, oligomeric reaction products with aniline and phosgene	500-079-6	32055-14-4	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0)	01/04/2022	16/05/2022	Details
Isononanoic acid, C16-18 (even numbered)-alkyl esters	601-141-6	111937-03-2	Long-term toxicity to fish	01/04/2022	16/05/2022	Details
o-(p-isocyanatobenzyl)phenyl isocyanate	227-534-9	5873-54-1	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0)	01/04/2022	16/05/2022	Details
pentasodium 4-amino-3-[{4-[(2,4-disulfonatophenyl)diazenyl]-3-methylphenyl}diazenyl]-5-hydroxy-6-[(4-nitro-2-sulfonatophenyl)diazenyl]naphthalene-1,7-disulfonate	948-569-2	-	Genetic toxicity in vivo	01/04/2022	16/05/2022	Details
Propanol, oxybis-, polymer with 1,1'-methylenebis[4-isocyanatobenzene]	701-040-8	59952-43-1	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	01/04/2022	16/05/2022	Details
Reaction mass of 2,5,8,11-tetraoxatridecan-13-ol and 2,5,8,11,14-pentaoxahexadecan-16-ol	915-389-0	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC no. 203-962-1)	01/04/2022	16/05/2022	Details
Reaction products of diphenylamine with nonene, branched	701-385-4	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	01/04/2022	16/05/2022	Details
Tar, wood	294-436-0	91722-33-7	Reproductive toxicity (pre-natal developmental toxicity)	23/02/2022	12/04/2022	Details
Sodium metavanadate	237-272-7	13718-26-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	25/01/2022 25/01/2022	11/03/2022 11/03/2022	Details
1-butylpyrrolidin-2-one	222-437-8	3470-98-2	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/01/2022	11/03/2022	Details
5-amino-2-nitrobenzoic acid	236-283-4	13280-60-9	Genetic toxicity in vivo	25/01/2022	11/03/2022	Details
Reaction products of [3-(2,3-epoxypropoxy)propyl]trimethoxysilane and triacetoxyvinylsilane	701-409-3	-	Genetic toxicity in vivo	25/01/2022	11/03/2022	Details
Perfluamine	206-420-2	338-83-0	Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts	283-392-8	84605-29-8	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) and another read-across member from ZDDP category Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and iso-Pr) esters, zinc salts	288-917-4	85940-28-9	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with a read-across member of the ZDDP category Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and pentyl) esters, zinc salts	273-527-9	68988-45-4	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with a read-across member of the ZDDP category(identity of test material not yet decided) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu) esters, zinc salts	270-478-5	68442-22-8	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) and another relevant read-across member of the ZDDP category Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts	272-723-1	68909-93-3	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts	270-608-0	68457-79-4	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with the substance, with Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Phosphorodithioic acid, mixed O,O-bis(sec-Bu and 1,3-dimethylbutyl) esters, zinc salts	272-238-5	68784-31-6	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with another ZDDP read-across category member depending on the outcome of the other testing proposals Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Zinc bis(O,O-diisooctyl) bis(dithiophosphate)	249-109-7	28629-66-5	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate)	224-235-5	4259-15-8	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with the substance and with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with the substance and with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Zinc bis[O-(2-ethylhexyl)] bis[O-(isobutyl)] bis(dithiophosphate)	247-810-2	26566-95-0	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with another ZDDP category member to be determined based on outcome of other testing proposals Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate)	230-257-6	6990-43-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Zinc O,O,O',O'-tetrakis(1,3-dimethylbutyl) bis(phosphorodithioate)	218-679-9	2215-35-2	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with, zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Phthalic acid	201-873-2	88-99-3	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with phthalic anhydride (EC no. 201-607-5) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with phthalic anhydride (EC no. 201-607-5)	21/12/2021 21/12/2021	04/02/2022 04/02/2022	Details
Alcohols, C11-14-iso-, C13-rich	271-235-6	68526-86-3	Reproductive toxicity (pre-natal developmental toxicity)	21/12/2021	04/02/2022	Details
Dihydrogen hexahydroxyplatinate	257-471-2	51850-20-5	Genetic toxicity in vivo \|\| Note: testing proposed with dihydrogen hexahydroxyplatinate, compound with 2-aminoethanol (1:2) (EC 268-717-3)	21/12/2021	04/02/2022	Details
Dihydrogen hexahydroxyplatinate, compound with 2-aminoethanol (1:2)	268-717-3	68133-90-4	Genetic toxicity in vivo	21/12/2021	04/02/2022	Details
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene	939-009-8	-	Sub-chronic toxicity (90-day): oral	21/12/2021	04/02/2022	Details
Reaction mass of Sodiumbis[1-[(2-hydroxy-5-nitrophenyl)azo]-2-naphtholato(2-)]chromate(1-) and Sodium [1-[(2-hydroxy-4-nitrophenyl)azo]-2-naphtholato(2-)][1-[(2-hydroxy-5-nitrophenyl)azo]-2-naphtholato(2-)]chromate(1-) and Sodiumbis[1-[(2-hydroxy-4-nitrophenyl)azo]-2-naphtholato(2-)]chromate(1-)	915-756-5	-	Genetic toxicity in vivo	21/12/2021	04/02/2022	Details
hexadecyltrimethoxysilane	240-464-3	16415-12-6	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021 25/11/2021	10/01/2022 10/01/2022	Details
Saccharomyces cerevisiae cell wall, extracted	949-711-6	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8)	25/11/2021 25/11/2021	10/01/2022 10/01/2022	Details
1,2-diacetoxybut-3-ene	421-720-5	18085-02-4	Sub-chronic toxicity (90-day): oral	25/11/2021	10/01/2022	Details
1,3-Benzenediamine, coupled with diazotized m-phenylenediamine, acetates	282-617-7	84281-74-3	Genetic toxicity in vivo	25/11/2021	10/01/2022	Details
4,4'-methylenediphenyl diisocyanate	202-966-0	101-68-8	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/11/2021	10/01/2022	Details
4-methylmorpholine	203-640-0	109-02-4	Sub-chronic toxicity (90-day): oral	25/11/2021	10/01/2022	Details
C,C'-azodi(formamide)	204-650-8	123-77-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/11/2021	10/01/2022	Details
Diundecyl phthalate	222-884-9	3648-20-2	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
Magnesium metaborate	237-235-5	13703-82-7	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
Reaction products of 5,5-dimethylhydantoin and ethylene oxide	701-388-0	-	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
Reaction products of amines, polyethylenepoly-, tetraethylenepentamine fraction and copper sulphate (1:1)	701-400-4	-	Genetic toxicity in vivo	25/11/2021	10/01/2022	Details
Reaction products of amines, polyethylenepoly-, triethylenetetramine fraction and copper sulphate (1:1)	701-399-0	-	"Genetic toxicity in vivo \|\| Note: testing proposed with Reaction products of amines, polyethylenepoly-, tetraethylenepentamine fraction and copper sulphate (1:1) (EC 701-400-4)"	25/11/2021	10/01/2022	Details
Reaction products of diazotised 4,4-diaminodiphenylamine-2-sulfonic acid, subsequently coupled with 6-amino-4-hydroxynaphthalene-2-sulfonic acid, further diazotised and coupled with metaphenylendiamine, sodium salts	939-382-7	-	Genetic toxicity in vivo	25/11/2021	10/01/2022	Details
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol	916-899-6	-	Long-term toxicity to fish	25/11/2021	10/01/2022	Details
Sulphamidic acid	226-218-8	5329-14-6	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
SUMILIZER GP	442-450-4	-	Long-term toxicity to fish	25/11/2021	10/01/2022	Details
Tetraammineplatinum dichloride	237-706-5	13933-32-9	Genetic toxicity in vivo	25/11/2021	10/01/2022	Details
Vinylene carbonate	212-825-5	872-36-6	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
Lithium bis(fluorosulfonyl)imide	686-526-7	171611-11-3	Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	21/10/2021 21/10/2021 21/10/2021	07/12/2021 07/12/2021 07/12/2021	Details
Ditolyl ether	248-948-6	28299-41-4	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	21/10/2021 21/10/2021	07/12/2021 07/12/2021	Details
2,7-naphthalenedisulfonic acid, 4-amino-5-hydroxy-, diazotized, coupled with diazotized 2-amino-4,6-dinitrophenol, diazotized 4-nitrobenzenamine and resorcinol, sodium salts	232-380-0	8011-86-7	Genetic toxicity in vivo	21/10/2021	07/12/2021	Details
2-(2-(2-ethoxyethoxy)ethoxy)ethanol	203-978-9	112-50-5	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1)	21/10/2021	07/12/2021	Details
3,6,9,12-tetraoxotridecanol	245-883-5	23783-42-8	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1)	21/10/2021	07/12/2021	Details
Carboxylic acids, di-, C4-6	271-678-5	68603-87-2	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with adipic acid (EC 204-673-3)	21/10/2021	07/12/2021	Details
Decanal	203-957-4	112-31-2	Reproductive toxicity (pre-natal developmental toxicity)	21/10/2021	07/12/2021	Details
Disodium [2,4-dihydro-4-[(2-hydroxy-5-nitrophenyl)azo]-5-methyl-2-phenyl-3H-pyrazol-3-onato(2-)][3-hydroxy-4-[(2-hydroxy-1-naphthyl)azo]-7-nitronaphthalene-1-sulphonato(3-)]chromate(2-)	274-490-1	70236-60-1	Genetic toxicity in vivo	21/10/2021	07/12/2021	Details
n-methyl-n-[c18-(unsaturated)alkanoyl]glycine	701-177-3	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	21/10/2021	07/12/2021	Details
N-Phenyl-diethanolamine, reaction products with formaldehyde	942-131-4	-	Reproductive toxicity (pre-natal developmental toxicity)	21/10/2021	07/12/2021	Details
Polysulfides, bis[3-(triethoxysilyl)propyl]	915-673-4	-	Sub-chronic toxicity (90-day): oral	21/10/2021	07/12/2021	Details
Propanamide, 2-hydroxy-N,N-dimethyl-	609-066-0	35123-06-9	Reproductive toxicity (extended one-generation reproductive toxicity study)	21/10/2021	07/12/2021	Details
Fatty acids, C12-14 (even numbered), methyl ester	629-776-4	308065-15-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021 30/09/2021	15/11/2021 15/11/2021 15/11/2021	Details
n4,n4'-hexane-1,6-diylbis[n-butyl-6-chloro-n,n'-bis(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,5-triazine-2,4-diamine]	835-183-3	83420-16-0	Bioaccumulation aquatic / sediment Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021 30/09/2021	15/11/2021 15/11/2021 15/11/2021	Details
Tetrakis(phenylmethyl)thioperoxydi(carbothioamide)	404-310-0	10591-85-2	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021 30/09/2021	15/11/2021 15/11/2021 15/11/2021	Details
3-(trimethoxysilyl)propyl isocyanate	239-415-9	15396-00-6	Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: it is proposed to use the information from an ongoing study with 3-(trimethoxysilyl)propylamine (EC 237-511-5)	30/09/2021 30/09/2021	15/11/2021 15/11/2021	Details
Ethylene	200-815-3	74-85-1	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021	15/11/2021 15/11/2021	Details
Saccharomyces cerevisiae, lysate	305-230-8	94350-12-6	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021	15/11/2021 15/11/2021	Details
1,1'-(methylenedi-p-phenylene)bismaleimide	237-163-4	13676-54-5	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021	15/11/2021	Details
3-methoxy-3-methylbutan-1-ol	260-252-4	56539-66-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	30/09/2021	15/11/2021	Details
A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate	413-750-2	-	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021	15/11/2021	Details
benzenesulfonic acid, 4-c10-13-alkyl derivs.-, salts with amines, c16-c18 (even numbered) alkyl	953-378-2	-	Long-term toxicity to fish	30/09/2021	15/11/2021	Details
BICYCLO[3.1.1]HEPT-2-ENE,2,6,6-TRIMETHYL-,POLYMER WITH 6,6-DIMETHYL-2-METHYLENEBICYCLO[3.1.1]HEPTANE	608-613-0	-	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021	15/11/2021	Details
Dodecanoic acid, 2,2-dimethyl-3-oxopropyl ester	468-880-2	102985-93-3	Long-term toxicity to fish	30/09/2021	15/11/2021	Details
Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (101-68-8), Octylamine (111-86-4) and Cyclohexylamine (108-91-8)	926-119-6	-	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (CAS: 101-68-8), Octylamine (111-86-4) and Hexamethylenediamine (124-09-4) (EC no 924-670-7)	30/09/2021	15/11/2021	Details
Sodium 2,4,5-trichlorobenzenesulphonate	258-548-3	53423-65-7	Genetic toxicity in vivo	30/09/2021	15/11/2021	Details
Alkane 6	438-390-3	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (extended one-generation reproductive toxicity study \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Dodecene, Dimer (EC 814-509-8), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
Branched hexatriacontane	417-070-7	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
N,N-dimethyl-N'-(2,2,6,6-tetramethylpiperidin-4-yl)propane-1,3-diamine	278-817-9	78014-16-1	Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate	425-220-8	5945-33-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
3-chloropropyltrimethoxysilane	219-787-9	2530-87-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
6,8-Dioxabicyclo[3.2.1]octan-4-one, (1S,5R) (Cyrene)	807-130-4	53716-82-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
N-(2-ethylhexyl)isononan-1-amide	810-288-7	1700656-13-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
Peracetic acid	201-186-8	79-21-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine	500-425-6	159034-91-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
1-Dodecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine	812-490-0	1312943-21-7	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (Octylamine and Hexamethylenediamine (EC no. 924-670-7)	26/08/2021	11/10/2021	Details
1-Octadecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine	812-491-6	1312943-23-9	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) , Octylamine) and Hexamethylenediamine (EC no. 924-670-7)	26/08/2021	11/10/2021	Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs.	272-221-2	68784-12-3	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
2,6-dimethyloct-7-en-2-ol	242-362-4	18479-58-8	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
2-[2,2-bis(2-prop-2-enoyloxyethoxymethyl)butoxy]ethyl 3-(dibutylamino)propanoate	701-363-4	-	Sub-chronic toxicity (90-day): oral	26/08/2021	11/10/2021	Details
3-(isodecyloxy)propylammonium acetate	249-166-8	28701-67-9	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
6-(cyclohexylamino)-3-methyl-3H-dibenz[f,ij]isoquinoline-2,7-dione	244-320-0	21295-57-8	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
Diphosphoric acid, compound with 1,3,5-triazine-2,4,6-triamine	239-590-1	15541-60-3	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
Disodium; 4-Amino-3-{4-[4-(2,4-diamino-phenylazo)-benzenesulfonylamino]-phenylazo}-5-hydroxy-6-phenylazo-naphthalene-2,7-disulfonate	605-104-5	157577-99-6	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
Hydrocarbons, C18-C22, n-alkanes, n-alkenes (Waksol A)	953-917-1	-	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
Linseed oil, oxidized	272-038-8	68649-95-6	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
Manganese carbonate	209-942-9	598-62-9	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
N-Phenyl-diethanolamine, reaction products with formaldehyde	942-131-4	-	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
Phenol, 2-methoxy-, reaction products with 2,2-dimethyl-3-methylenebicyclo[2.2.1]heptane, hydrogenated	275-062-7	70955-71-4	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/08/2021	11/10/2021	Details
platinum(IV) nitrate/nitric acid solution	432-400-1	-	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl	905-837-3	-	Long-term toxicity to fish \|\| Note: substance forms part of category; testing is also proposed with Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI), Octylamine and Hexamethylenediamine (EC no. 923-615-4)	26/08/2021	11/10/2021	Details
Reaction mass of dipotassium 3,3'-sulphonylbis(benzenesulphonate) and potassium 3-(phenylsulphonyl)benzenesulphonate	915-932-1	-	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
1-Dodecene, dimer with 1-decene, hydrogenated	604-766-2	151006-58-5	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-decene, dimer (EC 917-709-4) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-Dodecene, Dimer (EC 814-509-8) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)	01/07/2021 01/07/2021 01/07/2021	16/08/2021 16/08/2021 16/08/2021	Details
A mixture of isomers of branched tetracosane	417-060-2	151006-61-0	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 1-decene, dimer (EC 917-709-4), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)	01/07/2021 01/07/2021 01/07/2021	16/08/2021 16/08/2021 16/08/2021	Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene]	306-832-3	97416-84-7	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021 01/07/2021	16/08/2021 16/08/2021	Details
1-hydroxy-4-[[4-[(methylsulphonyl)oxy]phenyl]amino]anthraquinone	216-475-4	1594-08-7	Genetic toxicity in vivo	01/07/2021	16/08/2021	Details
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate)	202-319-2	94-28-0	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021	16/08/2021	Details
2,4,6-tri-tert-butylphenol	211-989-5	732-26-3	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021	16/08/2021	Details
Bis[2-[2-(1-methylethyl)-3-oxazolidinyl]ethyl] hexan-1,2-diylbiscarbamate	261-879-6	59719-67-4	Genetic toxicity in vivo	01/07/2021	16/08/2021	Details
Cyclohexyldimethylamine	202-715-5	98-94-2	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021	16/08/2021	Details
Disodium 4-amino-3,6-bis[[4-[(2,4-diaminophenyl)azo]phenyl]azo]-5-hydroxynaphthalene-2,7-disulphonate	229-208-1	6428-31-5	Genetic toxicity in vivo	01/07/2021	16/08/2021	Details
Inorganic phosphorus salt	428-310-5	-	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021	16/08/2021	Details
Linalool	201-134-4	78-70-6	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021	16/08/2021	Details
Pentaerythritol tetrakis(3-mercaptopropionate)	231-472-8	7575-23-7	Long-term toxicity to fish	01/07/2021	16/08/2021	Details
Reaction mass of trisodium [μ-[4-[[3,3'-dihydroxy-4'-[(2-hydroxy-6-sulpho-1-naphthyl)azo][1,1'-biphenyl]-4-yl]azo]-3-hydroxynaphthalene-2,7-disulphonato(7-)]]dicuprate(3-) and triammonium [μ-[4-[[3,3'-dihydroxy-4'-[(2-hydroxy-6-sulpho-1-naphthyl)azo][1,1'-biphenyl]-4-yl]azo]-3-hydroxynaphthalene-2,7-disulphonato(7-)]]dicuprate(3-)	945-577-8	-	Sub-chronic toxicity (90-day): oral	01/07/2021	16/08/2021	Details
Tris(nitrato-O)nitrosylruthenium	252-068-8	34513-98-9	Genetic toxicity in vivo	01/07/2021	16/08/2021	Details
Vinylene carbonate	212-825-5	872-36-6	Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	20/05/2021 20/05/2021 20/05/2021	05/07/2021 05/07/2021 05/07/2021	Details
N-pentan-2-ylidenehydroxylamine	484-470-6	623-40-5	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	20/05/2021 20/05/2021	05/07/2021 05/07/2021	Details
undec-10-enoic acid	203-965-8	112-38-9	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	20/05/2021 20/05/2021	05/07/2021 05/07/2021	Details
Condensation products of phenol and salicylaldehyde	947-320-5	-	Genetic toxicity in vivo	20/05/2021	05/07/2021	Details
Iron, complexes with diazotized 5-amino-2-(phenylamino)benzenesulfonic acid monosodium salt coupled with 4-[(2-hydroxy-3,5-dinitrophenyl)azo]-1,3-benzenediol, diazotized 4-nitrobenzenamine and diazotized 3-aminobenzenesulfonic acid monosodium salt	276-464-5	72207-77-3	Genetic toxicity in vivo \|\| Note: testing proposed with Acid Brown 360 (EC 946-788-8)	20/05/2021	05/07/2021	Details
N-(4-amino-9,10-dihydro-3-methoxy-9,10-dioxo-1-anthryl)-4-methylbenzenesulphonamide	201-369-2	81-68-5	Genetic toxicity in vivo	20/05/2021	05/07/2021	Details
Potassium hexadecyl hydrogen phosphate	242-768-1	19035-79-1	Reproductive toxicity (pre-natal developmental toxicity)	20/05/2021	05/07/2021	Details
(octahydro-4,7-methano-1H-indenediyl)bis(methylene) diacrylate	255-901-3	42594-17-2	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	22/04/2021 22/04/2021 22/04/2021	07/06/2021 07/06/2021 07/06/2021	Details
Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction	270-728-3	68477-39-4	Sub-chronic toxicity (90-day): oral \|\| Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7)	22/04/2021 22/04/2021 22/04/2021	07/06/2021 07/06/2021 07/06/2021	Details
Extracts (petroleum), heavy naphtha solvent	265-099-7	64741-98-6	Sub-chronic toxicity (90-day): oral \|\| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)	22/04/2021 22/04/2021 22/04/2021	07/06/2021 07/06/2021 07/06/2021	Details
Naphtha (petroleum), steam-cracked middle arom.	271-138-9	68516-20-1	Sub-chronic toxicity (90-day): oral \|\| Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)	22/04/2021 22/04/2021 22/04/2021	07/06/2021 07/06/2021 07/06/2021	Details
Solvent naphtha (petroleum), heavy arom.	265-198-5	64742-94-5	Sub-chronic toxicity (90-day): oral \|\| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)	22/04/2021 22/04/2021 22/04/2021	07/06/2021 07/06/2021 07/06/2021	Details
1,1,1,2,2,4,5,5,5-nonafluoro-4-(trifluoromethyl )-3-pentanone	436-710-6	756-13-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	22/04/2021 22/04/2021	07/06/2021 07/06/2021	Details
Sodium hydrogen-5-sulphoisophthalate	228-845-2	6362-79-4	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	22/04/2021 22/04/2021	07/06/2021 07/06/2021	Details
1,8-naphthylenediamine	207-529-8	479-27-6	Genetic toxicity in vivo	22/04/2021	07/06/2021	Details
2,2'-[(1-methylethylidene)bis(cyclohexane-4,1-diyloxymethylene)]bisoxirane	236-502-3	13410-58-7	Genetic toxicity in vivo	22/04/2021	07/06/2021	Details
7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt; 7-amino-3-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxy-8-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; 7-amino-8-[4-(2-sulfoxyethylsulfonyl)-phenylazo]-4-hydroxy-3-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; reaction mass of: 7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt	429-070-4	-	Sub-chronic toxicity (90-day): oral	22/04/2021	07/06/2021	Details
benzenesulfonic acid, mono- and dialkylation products with c16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic c15-c50	701-356-6	-	Long-term toxicity to fish	22/04/2021	07/06/2021	Details
Bis(O,O-diisopropyl dithiophosphate)bis(cyclohexylamine) zinc	809-986-4	52585-16-7	Genetic toxicity in vivo	22/04/2021	07/06/2021	Details
Butane-1,4-diol	203-786-5	110-63-4	Reproductive toxicity (extended one-generation reproductive toxicity study)	22/04/2021	07/06/2021	Details
N-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]-2-methyl-prop-2-enamide	611-915-5	59941-98-9	Genetic toxicity in vivo	22/04/2021	07/06/2021	Details
o-xylene	202-422-2	95-47-6	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with p-xylene (EC 203-396-5)	22/04/2021	07/06/2021	Details
Reaction products of C18 (unsaturated) fatty acids and dimethyl sulfate and triethanolamine	931-216-1	-	Long-term toxicity to fish \|\| Note: testing proposed with Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with diethylene triamine, di-Me sulfate quaternized (EC 937-237-2)	22/04/2021	07/06/2021	Details

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