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Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
4-tert-butylpyrocatechol 202-653-9 98-29-3
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/04/2011
29/04/2011
29/04/2011
14/06/2011
14/06/2011
14/06/2011
4-tert-butylpyrocatechol 202-653-9 98-29-3
Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (extended one-generation reproductive toxicity study)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Itaconic acid 202-599-6 - Reproductive toxicity (two-generation reproductive toxicity) 16/01/2012 01/03/2012
2,4-di-tert-butylphenol 202-532-0 96-76-4 Sub-chronic toxicity (90-day): oral 16/05/2011 30/06/2011
tetrahydro-2-methylfuran 202-507-4 96-47-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
23/01/2015
23/01/2015
09/03/2015
09/03/2015
Imidazolidine-2-thione 202-506-9 96-45-7 Long-term toxicity to fish 29/04/2011 14/06/2011
Pentan-3-one 202-490-3 96-22-0 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011
Benzotriazole 202-394-1 95-14-7 Reproductive toxicity (pre-natal developmental toxicity) 22/10/2013 05/12/2013
Dimethyl cyclohexane-1,4-dicarboxylate 202-347-5 94-60-0 Reproductive toxicity (pre-natal developmental toxicity) 15/04/2014 30/05/2014
Ethylene dibenzoate 202-338-6 94-49-5
Developmental neurotoxicity
Reproductive toxicity (pre-natal developmental toxicity 
21/05/2018
21/05/2018
05/07/2018
05/07/2018
Dibenzoyl peroxide 202-327-6 94-36-0 Reproductive toxicity (pre-natal developmental toxicity) 16/06/2011 01/08/2011
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate) 202-319-2 94-28-0 Sub-chronic toxicity (90-day): oral 26/01/2011 14/03/2011
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate) 202-319-2 94-28-0 Reproductive toxicity (two-generation reproductive toxicity) 18/09/2014 03/11/2014
Vinyl 2-ethylhexanoate 202-297-4 94-04-2 Reproductive toxicity (two-generation reproductive toxicity) 14/10/2011 28/11/2011
2-(2-naphthyloxy)ethanol 202-228-8 93-20-9 Genetic toxicity in vivo 16/05/2014 30/06/2014
Biphenyl-4,4'-diol 202-200-5 92-88-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Biphenyl-4,4'-diol 202-200-5 92-88-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/04/2019
26/04/2019
10/06/2019
10/06/2019
Biphenyl 202-163-5 92-52-4 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2018 19/03/2018
6-phenyl-1,3,5-triazine-2,4-diamine 202-095-6 91-76-9 Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity) 12/06/2013 29/07/2013
Decahydronaphthalene 202-046-9 91-17-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
decahydronaphthalene 202-046-9 91-17-8 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011
Menthol 201-939-0 89-78-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017
2-tert-butylphenol 201-807-2 88-18-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
1,3-diethyldiphenylurea 201-645-2 85-98-3 Sub-chronic toxicity (90-day): oral 03/03/2014 17/04/2014
2-ethylanthraquinone 201-535-4 84-51-5
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2014
18/02/2014
04/04/2014
04/04/2014
6,15-dihydroanthrazine-5,9,14,18-tetrone 201-375-5 81-77-6 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
1,3-dimethylimidazolidin-2-one 201-304-8 80-73-9 Reproductive toxicity (two-generation reproductive toxicity) 15/04/2014 30/05/2014
4,4'-oxydi(benzenesulphonohydrazide) 201-286-1 80-51-3
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
21/03/2014
05/05/2014
05/05/2014
05/05/2014
Bis(α,α-dimethylbenzyl) peroxide 201-279-3 80-43-3 Reproductive toxicity (pre-natal developmental toxicity 20/10/2016 05/12/2016
bis(α,α-dimethylbenzyl) peroxide 201-279-3 80-43-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
01/08/2011
01/08/2011
dichloro(diphenyl)silane 201-251-0 80-10-4
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9)
Sub-chronic toxicity (90-day): oral
Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
4,4'-sulfonyldiphenol 201-250-5 80-09-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
30/05/2011
30/05/2011
bis(4-chlorophenyl) sulphone 201-247-9 80-07-9
Bioaccumulation: terrestrial
Reproductive toxicity (pre-natal developmental toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Bis(4-chlorophenyl) sulphone 201-247-9 80-07-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Reproductive toxicity (pre-natal developmental toxicity) 06/09/2018 22/10/2018
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Long-term toxicity to fish 17/06/2014 01/08/2014
2,5-di-tert-pentylhydroquinone 201-222-2 79-74-3 Sub-chronic toxicity (90-day): oral 31/05/2011 15/07/2011
Nitroethane 201-188-9 79-24-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with nitromethane (EC 200-876-6) 10/03/2017 25/04/2017
Chloroacetic acid 201-178-4 79-11-8 Reproductive toxicity (pre-natal developmental toxicity) 14/10/2011 28/11/2011
Chloroacetic acid 201-178-4 79-11-8 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011
1-aminopropan-2-ol 201-162-7 78-96-6 Reproductive toxicity (pre-natal developmental toxicity) 17/09/2019 01/11/2019
2,2'-dimethyl-2,2'-azodipropiononitrile 201-132-3 78-67-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/03/2011
15/03/2011
15/03/2011
29/04/2011
29/04/2011
29/04/2011
2,2'-dimethyl-2,2'-azodipropiononitrile 201-132-3 78-67-1 Reproductive toxicity (pre-natal developmental toxicity) 03/02/2016 21/03/2016
di-tert-butyl 1,1,4,4-tetramethyltetramethylene diperoxide 201-128-1 78-63-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/10/2011
14/10/2011
28/11/2011
28/11/2011
Tris(2-butoxyethyl) phosphate 201-122-9 78-51-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
tris(2-butoxyethyl) phosphate 201-122-9 78-51-3 Reproductive toxicity (two-generation reproductive toxicity) 01/07/2011 15/08/2011
1-ethynylcyclohexanol 201-100-9 78-27-3 Sub-chronic toxicity (90-day): oral 18/02/2014 04/04/2014
Triethoxy(vinyl)silane 201-081-7 78-08-0
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Tetraethyllead 201-075-4 78-00-2 Sub-chronic toxicity study (90-day) 01/07/2011 15/08/2011
Propylidynetrimethanol 201-074-9 77-99-6 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2011 30/06/2011
Propylidynetrimethanol 201-074-9 77-99-6 Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed on rabbits 16/05/2014 30/06/2014
tetraethylammonium hydroxide 201-073-3 77-98-5 Sub-chronic toxicity (90-day): oral || Note: testing proposed with N,N,N-trimethylmethanaminium chloride (EC 200-880-8; CAS 75-57-0) 30/09/2015 16/11/2015
Trometamol 201-064-4 77-86-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-amino-1,3-propanediol
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-amino-1,3-propanediol
17/06/2014
17/06/2014
01/08/2014
01/08/2014
3a,4,7,7a-tetrahydro-4,7-methanoindene 201-052-9 77-73-6 Reproductive toxicity (pre-natal developmental toxicity) 28/02/2019 15/04/2019
Perfluoroethane 200-939-8 76-16-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
Trichloroacetic acid 200-927-2 76-03-9 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011
Trichloroacetic acid 200-927-2 76-03-9 Reproductive toxicity (pre-natal developmental toxicity) 14/10/2011 28/11/2011
Pivalic acid 200-922-5 75-98-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/12/2017
20/12/2017
20/12/2017
05/02/2018
05/02/2018
05/02/2018
Tetramethylammonium chloride 200-880-8 75-57-0 Sub-chronic toxicity (90-day): oral 29/04/2014 13/06/2014
Nitromethane 200-876-6 75-52-5 Reproductive toxicity (pre-natal developmental toxicity) 04/04/2014 19/05/2014
2-chloropropane 200-858-8 75-29-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
2-chloropropane 200-858-8 75-29-6 Reproductive toxicity (two-generation reproductive toxicity) 16/05/2011 30/06/2011
Chloroethane 200-830-5 75-00-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
10/03/2017
10/03/2017
25/04/2017
25/04/2017
Methylamine 200-820-0 74-89-5 Genetic toxicity in vivo 14/02/2011 31/03/2011
Cobalt(II) diacetate 200-755-8 71-48-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Hexanal 200-624-5 66-25-1 Genetic toxicity in vivo “|| Note: Testing proposal is based on concern identified by the registrant.” 27/05/2019 11/07/2019
Tetrasodium ethylenediaminetetraacetate 200-573-9 64-02-8 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011
Diethyl ether 200-467-2 60-29-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 02/11/2018 17/12/2018
diethyl ether 200-467-2 60-29-7 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011
2-mercaptoethanol 200-464-6 60-24-2 Reproductive toxicity (pre-natal developmental toxicity) 15/04/2011 30/05/2011
2-phenylethanol 200-456-2 60-12-8 Reproductive toxicity (two-generation reproductive toxicity) 15/04/2014 30/05/2014
Edetic acid 200-449-4 60-00-4 Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with_Na2H2EDTA (identifier not available) 16/06/2011 01/08/2011
benzyltrimethylammonium chloride 200-300-3 56-93-9 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2014 17/03/2014
3,3'-iminodi(propylamine) 200-261-2 56-18-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives - - Sub-chronic toxicity (90-day): oral 30/06/2016 15/08/2016
3,5-bis(2,4-dimethylcyclohex-3-en-1-yl)polyheterocycle - - Genetic toxicity in vivo 16/03/2015 30/04/2015
3-[(diisoalkyloxyphosphorothioyl)thio]-2-methylalkanoic acid - - Developmental toxicity (pre-natal developmental toxicity) 15/03/2011 29/04/2011
Addition products of m-phenylenebis(methylamine) with reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethyl 5-isocyanato-2-methylphenylcarbamate, 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-4-methylphenylcarbamate and 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-2-methylphenylcarbamate - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on potential concern identified by the registrant.
Sub-chronic toxicity (90 day): oral
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
Alkenes, C13-14 - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Alkenes, C13-14, hydroformylation products, low boiling - - Reproductive toxicity (two-generation reproductive toxicity) 29/07/2011 12/09/2011
Alkenes, C6-8, even and odd, linear and branched - - Sub-chronic toxicity (90-day): oral 25/06/2012 09/08/2012
Alkenes, C6-8, even and odd, linear and branched - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
alkyl amine and alkylbenzenesulphonate - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Aluminium tris(dialkylphosphinate) - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
23/06/2011
23/06/2011
08/08/2011
08/08/2011
Amides, C18 (unsaturated) - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Amides, C22 (unsaturated) - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Amides, C8-18(even-numbered) and C18(unsatd.), N-(2-hydroxypropyl) - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Bis(nonylphenyl)amine / Reaction products of Benzeneamine, N-phenyl- with nonene (branched) - -
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
28/02/2011
28/02/2011
14/04/2011
14/04/2011
boron orthophosphate - 13308-51-5 Reproductive toxicity (pre-natal developmental toxicity) 30/06/2016 15/08/2016
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distilled - -
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Cashew, nutshell liq., oligomeric reaction products with 1-chloro-2,3-epoxypropane - 68413-24-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Condensation products of triethanolamine with addition products of fatty acids, C18 (unsaturated) alkyl with maleic anhydride - -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/03/2017
10/03/2017
10/03/2017
25/04/2017
25/04/2017
25/04/2017
Coupling reaction products of diazotized 2-amino-6-[(2-substituted ethyl)sulfonyl]naphthalene-1-subsituted acid with 4-({4-chloro-6-[ethyl(3-{[2-(substituted oxy)ethyl]sulfonyl}phenyl)amino]-heteromonocycl-2-yl}amino)-5-hydroxynaphthalene-2,7-disubstituted acid and their sodium and potassium salts - - 7.6.2 Mammalian erythrocyte micronucleus test according to OECD 474 03/12/2010 17/01/2011
Disodium hydroxy-substituted alkanoate - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Ethanaminium, 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethyl-, esters with C16-18 and C18 unsatd. fatty acids, chlorides - 1079184-43-2 Reproductive toxicity (two-generation reproductive toxicity) 26/04/2010 10/06/2010
Ethoxypropyl-hydroxy-hexanamide - - Reproductive/developmental toxicity 04/12/2009 18/01/2010
Fatty acids, C14-18 and C16-18-unsatd., maleated - 85711-46-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
11/11/2016
11/11/2016
11/11/2016
03/01/2017
03/01/2017
03/01/2017
Halophosphate - - Sub-chronic toxicity (90 day): inhalation 15/07/2014 29/08/2014
Hydrogenated oligomerisation product, including dimers and trimers, of tetradec-1-ene and alkene - -
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
10/08/2009
10/08/2009
24/09/2009
24/09/2009
N-benzyl-N-C16-18 (even numbered)-alkyl-N-methyl-C16-18 (even numbered)-alkyl-1-aminium chloride - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
12/09/2011
12/09/2011



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