Predchádzajúce/výsledok

Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
Hydrocarbons, C9-C11, isoalkanes, cyclics, <2% aromatics 920-134-1 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, <2% aromatics 919-857-5 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-C12, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 919-446-0 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-unsaturated, polymerized 615-276-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Details
Hydrochloric acid, reaction products with aniline and nitrobenzene, sulfonated, sodium salts 291-454-0 90411-76-0 Reproductive toxicity (pre-natal developmental toxicity) 30/11/2015 14/01/2016 Details
Hydrogen [4-[[4-(diethylamino)phenyl][4-[ethyl[(3-sulphonatobenzyl)amino]-o-tolyl]methylene]-3-methylcyclohexa-2,5-dien-1-ylidene](ethyl)(3-sulphonatobenzyl)ammonium, sodium salt 229-390-2 6505-30-2 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021 Details
Hydrogenated oligomerisation product, including dimers and trimers, of tetradec-1-ene and alkene - -
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
10/08/2009
10/08/2009
24/09/2009
24/09/2009
Details
Hydroxyacetone 204-124-8 116-09-6 Genetic toxicity in vivo 23/11/2020 07/01/2021 Details
Hydroxycyclohexyl phenyl ketone 213-426-9 947-19-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 17/09/2019 01/11/2019 Details
Hydroxyethylated 2-butyne-1,4-diol 608-711-3 32167-31-0 Sub-chronic toxicity (90-day): oral 17/06/2014 01/08/2014 Details
Icos-1-ene 222-374-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Details
Icosane 204-018-1 112-95-8 Reproductive toxicity (two-generation reproductive toxicity)// Note: Testing proposed with Hydrocarbon, C9-C12, normal, isoalkane, cyclics, 2-25% aromatics; Hydrocarbon, C16-C20, normal, isoalkane cyclics, 2-30% aromatics 02/07/2013 16/08/2013 Details
Imidazolidine-2-thione 202-506-9 96-45-7 Long-term toxicity to fish 29/04/2011 14/06/2011 Details
Imidazolium compounds, 2-C17-unsatd.-alkyl-1-(2-C18-unsatd. amidoethyl)-4,5-dihydro-N-methyl, Me sulfates 931-745-8 - Sub-chronic toxicity (90-day): oral 01/07/2011 15/08/2011 Details
inorganic phosphorus salt 428-310-5 - Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Details
Inorganic phosphorus salt 428-310-5 - Reproductive toxicity (pre-natal developmental toxicity) 01/07/2021 16/08/2021 Details
Iron, complexes with diazotized 5-amino-2-(phenylamino)benzenesulfonic acid monosodium salt coupled with 4-[(2-hydroxy-3,5-dinitrophenyl)azo]-1,3-benzenediol, diazotized 4-nitrobenzenamine and diazotized 3-aminobenzenesulfonic acid monosodium salt 276-464-5 72207-77-3 Genetic toxicity in vivo || Note: testing proposed with Acid Brown 360 (EC 946-788-8) 20/05/2021 05/07/2021 Details
isliFe - - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 17/12/2019 31/01/2020 Details
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol 246-771-9 25265-77-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/04/2019
26/04/2019
26/04/2019
10/06/2019
10/06/2019
10/06/2019
Details
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol 246-771-9 25265-77-4 Reproductive toxicity (pre-natal developmental toxicity) 16/06/2011 01/08/2011 Details
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol 246-771-9 25265-77-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 22/09/2022 07/11/2022 Details
Isodecyl diphenyl phosphate 249-828-6 29761-21-5 Bioaccumulation aquatic / sediment 15/07/2011 29/08/2011 Details
Isodecyl methacrylate 249-978-2 29964-84-9
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
03/10/2023
03/10/2023
17/11/2023
17/11/2023
Details
Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane 224-506-8 4390-04-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
Isononanoic acid, C16-18 (even numbered)-alkyl esters 601-141-6 111937-03-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/06/2018 02/08/2018 Details
Isononanoic acid, C16-18 (even numbered)-alkyl esters 601-141-6 111937-03-2 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
Isononanoic acid, C16-18 (even numbered)-alkyl esters 601-141-6 111937-03-2 Long-term toxicity to fish 01/04/2022 16/05/2022 Details
Isononyl isononanoate 609-993-0 42131-25-9 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
Isooctyl acrylate 249-707-8 29590-42-9
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/03/2011
15/03/2011
29/04/2011
29/04/2011
Details
Isopropylcyclohexane 211-792-4 696-29-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
Isotridecan-1-ol 248-469-2 27458-92-0 Reproductive toxicity (pre-natal developmental toxicity) 20/12/2017 05/02/2018 Details
Isotridecan-1-ol 248-469-2 27458-92-0 Reproductive toxicity (extended one-generation reproductive toxicity study) 16/12/2020 01/02/2021 Details
Itaconic acid 202-599-6 - Reproductive toxicity (two-generation reproductive toxicity) 16/01/2012 01/03/2012 Details
Kieselguhr, soda ash flux-calcined 272-489-0 68855-54-9 Sub-chronic toxicity (90 day): inhalation 01/07/2011 15/08/2011 Details
l-Glutamic acid, N-coco acyl derivs., disodium salts 269-085-1 68187-30-4 Sub-chronic toxicity (90-day): oral 22/09/2022 07/11/2022 Details
l-Glutamic acid, N-coco acyl derivs., disodium salts 269-085-1 68187-30-4 Reproductive toxicity (pre-natal developmental toxicity) 18/09/2014 03/11/2014 Details
LiFePO4 476-700-9 - Reproductive toxicity (pre-natal developmental toxicity) 22/10/2013 05/12/2013 Details
Linalool 201-134-4 78-70-6 Reproductive toxicity (pre-natal developmental toxicity) 01/07/2021 16/08/2021 Details
Linalyl acetate 204-116-4 115-95-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 17/06/2020 03/08/2020 Details
Linseed oil, oxidized 272-038-8 68649-95-6 Genetic toxicity in vivo 01/07/2011 15/08/2011 Details
Linseed oil, oxidized 272-038-8 68649-95-6 Genetic toxicity in vivo 26/08/2021 11/10/2021 Details
Linseed oil, polymerized 614-114-9 67746-08-1 Reproductive toxicity (pre-natal developmental toxicity) 18/09/2014 03/11/2014 Details
Lithium bis(fluorosulfonyl)imide 686-526-7 171611-11-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/10/2021
21/10/2021
21/10/2021
07/12/2021
07/12/2021
07/12/2021
Details
Lithium bis(oxalato)borate 456-990-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/05/2019
27/05/2019
11/07/2019
11/07/2019
Details
Lithium carbonate 209-062-5 554-13-2 Reproductive toxicity (two-generation reproductive toxicity) 29/04/2011 14/06/2011 Details
Lithium chloride 231-212-3 7447-41-8 Reproductive toxicity (two-generation reproductive toxicity) 29/04/2011 14/06/2011 Details
Lithium chloride 231-212-3 7447-41-8 Genetic toxicity in vivo 03/11/2023 18/12/2023 Details
Lithium hydroxide 215-183-4 1310-65-2 Reproductive toxicity (two-generation reproductive toxicity) 29/04/2011 14/06/2011 Details
Lithium phosphorodifluoridate 643-080-8 24389-25-1 Reproductive toxicity (pre-natal developmental toxicity) 25/05/2020 09/07/2020 Details
Lithium tetrafluoroborate, anhydrous 238-178-9 14283-07-9 Genetic toxicity in vivo 25/05/2020 09/07/2020 Details
m-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline 275-662-9 71604-74-5
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Details
m-cresol 203-577-9 108-39-4 Long-term toxicity to fish|| Note: testing proposed with p-cresol (EC no. 203-398-6) 10/05/2022 27/06/2022 Details
m-phenylene di(acetate) 203-596-2 108-58-7 Genetic toxicity in vivo 27/01/2020 12/03/2020 Details
m-xylene 203-576-3 108-38-3 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with p-xylene (EC 203-396-5) 18/02/2021 05/04/2021 Details
Magnesium metaborate 237-235-5 13703-82-7 Reproductive toxicity (pre-natal developmental toxicity) 25/11/2021 10/01/2022 Details
Magnesium, bis(2-hydroxybenzoato-O1,O2)-, ar,ar'-di-C14-18alkyl derivs 931-371-5 - Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details
Maleic acid 203-742-5 110-16-7 Reproductive toxicity (pre-natal developmental toxicity) 17/06/2020 03/08/2020 Details
Manganese carbonate 209-942-9 598-62-9 Reproductive toxicity (pre-natal developmental toxicity) 26/08/2021 11/10/2021 Details
Manganese dioxide 215-202-6 1313-13-9 Genetic toxicity in vivo 23/11/2020 07/01/2021 Details
Melamine 203-615-4 108-78-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 17/05/2016 01/07/2016 Details
Menthol 201-939-0 89-78-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017 Details
Mequinol 205-769-8 150-76-5 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2011 14/06/2011 Details
Mercaptoacetic acid 200-677-4 68-11-1 Long-term toxicity to fish 31/01/2023 17/03/2023 Details
Methanal, reaction products with 1,3-bis(aminomethyl)benzene and hydroxybenzen 701-207-5 1950616-36-0
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/05/2018
21/05/2018
21/05/2018
05/07/2018
05/07/2018
05/07/2018
Details
Methyl 4-[[(2,5-dichlorophenyl)amino]carbonyl]-2-[[2-hydroxy-3-[[(2-methoxyphenyl)amino]carbonyl]-1-naphthyl]azo]benzoate – bulk and nano forms 263-272-1 61847-48-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 03/10/2023 17/11/2023 Details
Methyl [3-(trimethoxysilyl)propyl]carbamate 245-659-7 23432-62-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/03/2017
10/03/2017
10/03/2017
25/04/2017
25/04/2017
25/04/2017
Details
methyl acrylate; methyl propenoate 202-500-6 96-33-3 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
Methyl benzoylformate 239-263-3 15206-55-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/10/2022
26/10/2022
12/12/2022
12/12/2022
Details
Methyl isothiocyanate 209-132-5 556-61-6 Genetic toxicity in vivo 17/11/2011 02/01/2012 Details
Methyl trimethyl-3-[(1-oxododecyl)amino]propylammonium sulphate 234-204-8 10595-49-0 Reproductive toxicity (pre-natal developmental toxicity) 16/12/2020 01/02/2021 Details
methyl-1h-benzotriazole 249-596-6 29385-43-1 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate 16/12/2016 30/01/2017 Details
methyl-1h-benzotriazole 249-596-6 29385-43-1 Sub-chronic toxicity (90-day): oral 16/12/2020 01/02/2021 Details
Methylamine 200-820-0 74-89-5 Genetic toxicity in vivo 14/02/2011 31/03/2011 Details
Methylene-bis-4,1-(N-phenylene-N'-butylurea) 416-600-4 - Bioaccumulation aquatic / sediment 17/05/2016 01/07/2016 Details
Methylphosphonic acid 213-607-2 993-13-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4)
27/05/2019
27/05/2019
11/07/2019
11/07/2019
Details
methylsilanetriyl triacetate 224-221-9 4253-34-3 Sub-chronic toxicity (90-day): oral||Note: testing proposed with [triethoxy(methyl)silane] (CAS no. 2031-67-6) 03/10/2023 17/11/2023 Details
methylsilanetriyl triacetate 224-221-9 4253-34-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [Trimethoxy(methyl)silane] (EC 214-685-0) 16/03/2015 30/04/2015 Details
Middle distillate from refinery proces cofeeding vegetable oil 938-793-9 - Reproductive toxicity (two-generation reproductive toxicity) 02/09/2013 18/10/2013 Details
Mono- and/or di- and/or tri(1-phenylethyl)-m-cresol and p-cresol 700-427-9 -
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
01/12/2010
01/12/2010
01/12/2010
17/01/2011
17/01/2011
17/01/2011
Details
Morpholine, 4-C12-14-alkyl derivs. 800-906-3 1402434-48-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
Multi-Wall Carbon Nanotubes, synthetic graphite in tubular shape 231-955-3 7782-42-5 Long-term toxicity to fish 03/11/2011 19/12/2011 Details
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide 435-860-1 214417-91-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2012
17/04/2012
01/06/2012
01/06/2012
Details
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide 435-860-1 214417-91-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Details
N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine 229-761-9 6711-48-4 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with N,N-diethylpropane-1,3-diamine (EC no. 203-236-4) 22/09/2022 07/11/2022 Details
N,N''-(4-methyl-m-phenylene)bis[N',N'-dimethylurea] 241-523-6 17526-94-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
23/03/2020
23/03/2020
07/05/2020
07/05/2020
Details
N,N''-propane-1,3-diylbis[N'-octadecylurea 252-667-4 35674-65-8 Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) 29/03/2016 13/05/2016 Details
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide] 258-981-8 54112-23-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
12/12/2014
12/12/2014
26/01/2015
26/01/2015
Details
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide] 258-981-8 54112-23-1 Long-term toxicity to fish
Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
31/08/2015 15/10/2015 Details
N,N'-bis(2,2,6,6-tetramethyl-4-piperidyl)isophthalamide 419-710-0 -
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
12/12/2014
12/12/2014
12/12/2014
26/01/2015
26/01/2015
26/01/2015
Details
N,N'-bis(3-aminopropyl)ethylenediamine 234-147-9 10563-26-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/03/2021
18/03/2021
03/05/2021
03/05/2021
Details
N,N'-dimethyldiphenylthiuram disulphide 234-196-6 10591-84-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2019
16/08/2019
30/09/2019
30/09/2019
Details
N,N'-diphenyl-p-phenylenediamine 200-806-4 74-31-7
Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) 204-613-6 123-26-2
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with: “Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine”, CAS 100545-48-0
Sub-chronic toxicity (90 day): oral
30/09/2015
30/09/2015
30/09/2015
16/11/2015
16/11/2015
16/11/2015
Details
N,N'-hexane-1,6-diylbis(hexahydro-2-oxo-1H-azepine-1-carboxamide) 227-563-7 5888-87-9 Genetic toxicity in vivo 18/09/2014 03/11/2014 Details
N,N,2,8-tetramethyl-5,11-dioxa-2,8-diazatridecan-13-amine 695-748-3 65286-55-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
24/02/2020
24/02/2020
09/04/2020
09/04/2020
Details
N,N,N',N'-tetrakis(2,3-epoxypropyl)-m-xylene-α,α'-diamine 264-438-6 63738-22-7 Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020 12/03/2020 Details
N,N,N',N'-tetramethylhexamethylenediamine 203-842-9 111-18-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
Details
N,N,N`,N`,N``-Pentamethyl-N-C16-18 (even numbered) C18 unsat.-alkyl-1,3-propanediammonium chloride 629-716-7 1211950-04-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Details
N,N-bis(2-ethylhexyl)-5-methyl-1H-benzotriazole-1-methylamine, N,N-bis(2-ethylhexyl)-4-methyl-1H-benzotriazole-1-methylamine, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-4-methyl-, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-5-methyl-, 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-6-methyl-(Mixture) 939-700-4 - Sub-chronic toxicity (90-day): oral 21/10/2019 05/12/2019 Details
N,N-bis[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine 251-459-0 33329-35-0 Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with structurally-related compound 29/04/2014 13/06/2014 Details