Predchádzajúce/výsledok

Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
(E)-2-benzylideneoctanal 639-566-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Details
(Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated 926-000-9 - Reproductive toxicity (pre-natal developmental toxicity) 04/04/2014 19/05/2014 Details
(Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid 701-116-0 - Reproductive toxicity (pre-natal developmental toxicity) 23/03/2020 07/05/2020 Details
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol 204-137-9 -
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/01/2012
16/01/2012
16/01/2012
01/03/2012
01/03/2012
01/03/2012
Details
1,1'-Methylenebis(4-isocyanatobenzene) and 1,1'-methylenebis(4-isocyanatobenzene) homopolymer and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propane-1,2-diol 701-393-8 - Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) 16/06/2022 01/08/2022 Details
1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol 701-124-4 - Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) 01/04/2022 16/05/2022 Details
1,1'-methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with butane-1,3-diol, 2,2'-oxydiethanol and propane-1,2-diol 701-173-1 - Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) 01/04/2022 16/05/2022 Details
1,1'-methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol and oligomerization reaction products of oxydipropanol 701-041-3 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
16/06/2022
16/06/2022
16/06/2022
01/08/2022
01/08/2022
01/08/2022
Details
1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives - - Sub-chronic toxicity (90-day): oral 30/06/2016 15/08/2016 Details
1,2-Benzenedicarboxylic acid, benzyl C7-9-branched and linear alkyl esters 701-339-3 - Reproductive toxicity (pre-natal developmental toxicity) 25/05/2020 09/07/2020 Details
1,3- and 1,4-cyclohexandicarboxyaldehyde 482-020-3 - Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014 Details
1,3-Benzenedimethanamine, N-(2-phenylethyl) derivs. 445-790-1 - Sub-chronic toxicity (90 day): inhalation 04/04/2014 19/05/2014 Details
1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate 931-295-2 - Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
1,4-Cyclohexanedicarboxylic acid, 1,4-diisononyl ester 701-012-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/12/2018
10/12/2018
24/01/2019
24/01/2019
Details
1-(4-(ACETYLOXY)-3-((ACETYLOXY)METHYL)PHENYL)ETHANONE 921-042-4 - Genetic toxicity in vivo 25/05/2020 09/07/2020 Details
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 - Reproductive toxicity (pre-natal developmental toxicity) 18/02/2021 05/04/2021 Details
1-acetyl-4-(3-dodecyl-2,5-dioxo-1-pyrrolidinyl)-2,2,6,6-tetramethylpiperidine 411-930-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
12/01/2023
12/01/2023
Details
1-isocyanato-2(or 4)-(4-isocyanatobenzyl)benzene and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propylene glycol 701-029-8 - Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) 01/04/2022 16/05/2022 Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts 939-457-4 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
18/09/2014
03/11/2014
03/11/2014
03/11/2014
Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts 939-455-3 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
18/09/2014
18/09/2014
18/09/2014
03/11/2014
03/11/2014
03/11/2014
Details
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with Propylene oxide and n-butyl glycidyl ether 926-564-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/10/2019
21/10/2019
05/12/2019
05/12/2019
Details
2,2-bis(hydroxymethyl)propionic acid // 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid 225-306-3 -
Reproductive toxicity (pre-natal developmental toxicity study)
Sub-chronic oral toxicity (90-day): oral
05/04/2011
05/04/2011
20/05/2011
20/05/2011
Details
2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diethanol, .beta.3,.beta.3,.beta.9,.beta.9-tetramethyl- 485-230-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
12/01/2023
12/01/2023
Details
2,4-dimethyl-6-(1-methyl-pentadecyl)phenol 411-220-5 - Reproductive toxicity (pre-natal developmental toxicity) 25/09/2012 12/11/2012 Details
2-(2-Vinyloxyethoxy)ethyl acrylate 451-690-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/12/2017
20/12/2017
05/02/2018
05/02/2018
Details
2-[2,2-bis(2-prop-2-enoyloxyethoxymethyl)butoxy]ethyl 3-(dibutylamino)propanoate 701-363-4 - Sub-chronic toxicity (90-day): oral 26/08/2021 11/10/2021 Details
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone 404-360-3 - Reproductive toxicity (pre-natal developmental toxicity) 24/05/2013 08/07/2013 Details
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylated 614-503-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): inhalation
15/04/2011
15/04/2011
15/04/2011
30/05/2011
30/05/2011
30/05/2011
Details
2-ethoxyethyl-2-(4-(2,6-dihydro-2,6-dioxo-7-phenyl-1,5-dioxaindacen-3-yl)phenoxy)acetate 403-960-2 - Genetic toxicity in vivo 03/10/2023 17/11/2023 Details
2-ethyl-N,N-bis(2-ethylhexyl)hexylamine 217-461-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/01/2012
16/01/2012
01/03/2012
01/03/2012
Details
2-propenoic acid, butyl ester, reaction products with butadiene and sulfur 947-895-2 -
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/01/2024
15/01/2024
15/01/2024
15/01/2024
29/02/2024
29/02/2024
29/02/2024
29/02/2024
Details
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane 941-793-1 - Reproductive toxicity (pre-natal developmental toxicity) 26/04/2019 10/06/2019 Details
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane 941-793-1 - Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-Propyn-1-ol, compd. with methyloxirane (EC 609-530-2, CAS 38172-91-7) 17/04/2015 04/06/2015 Details
2-{N-[2,6-Diamino-4-oxo-4H-pyrimidin-(5Z)-ylidene]-hydrazino}-5-methyl-benzenesulfonic acid 700-002-8 - Reproductive toxicity (pre-natal developmental toxicity) 16/07/2012 30/08/2012 Details
3,4-dihydroxy-1-[(Z)-octadec-9-enyl]pyrrolidine-2,5-dione 700-233-4 -
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
04/09/2023
04/09/2023
04/09/2023
19/10/2023
19/10/2023
19/10/2023
Details
3,5,5-trimethylhexanoic acid 221-975-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
15/07/2011
15/07/2011
Details
3,5-bis(2,4-dimethylcyclohex-3-en-1-yl)polyheterocycle - - Genetic toxicity in vivo 16/03/2015 30/04/2015 Details
3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione 401-540-3 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/03/2018
26/03/2018
26/03/2018
11/05/2018
11/05/2018
11/05/2018
Details
3,6-bis(4-tert-butylphenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 416-250-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/09/2012 12/11/2012 Details
3,6-bis-biphenyl-4-yl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 413-920-6 - Reproductive toxicity (two-generation reproductive toxicity) 25/09/2012 12/11/2012 Details
3-((5-(3-(Dodecanoyloxy)-2,2-dimethylpropylideneamino)-1,3,3-trimethylcyclohexyl)methylimino)-2,2-dimethylpropyl dodecanoate 700-071-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2012
16/05/2012
02/07/2012
02/07/2012
Details
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine 939-485-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Details
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine acetate (1:1) 939-448-5 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)-
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)-
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Details
3-(Diisobutoxy-thiophosphorylsulfanyl)-2-methyl-propionic acid 434-070-2 - Sub-chronic toxicity (90-day): oral 18/02/2013 04/04/2013 Details
3-[(5-cyano-6-hydroxy-1,4-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)diazenyl]phenyl benzoate 953-951-7 - 7.6.2 Genetic toxicity in vivo 08/03/2024 22/04/2024 Details
3-[(diisoalkyloxyphosphorothioyl)thio]-2-methylalkanoic acid - - Developmental toxicity (pre-natal developmental toxicity) 15/03/2011 29/04/2011 Details
3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 931-324-9 - Sub-chronic toxicity (90-day): oral 02/09/2011 17/10/2011 Details
3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - Reproductive toxicity (pre-natal developmental toxicity) 26/03/2018 11/05/2018 Details
3-methyldecane; benzene; cyclooctane; nonane 941-364-9 - Reproductive toxicity (extended one-generation reproductive toxicity study) 05/07/2018 20/08/2018 Details
3-{[3-(C10-16-oxy)propyl]amino}propan-1-aminium acetate 941-152-6 - Sub-chronic toxicity (90-day): oral||Note: testing proposed with 1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC: 931-295-2) 15/07/2022 29/08/2022 Details