Predchádzajúce/výsledok

Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives - - Sub-chronic toxicity (90-day): oral 30/06/2016 15/08/2016 Details
3,5-bis(2,4-dimethylcyclohex-3-en-1-yl)polyheterocycle - - Genetic toxicity in vivo 16/03/2015 30/04/2015 Details
3-[(diisoalkyloxyphosphorothioyl)thio]-2-methylalkanoic acid - - Developmental toxicity (pre-natal developmental toxicity) 15/03/2011 29/04/2011 Details
Addition products of m-phenylenebis(methylamine) with reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethyl 5-isocyanato-2-methylphenylcarbamate, 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-4-methylphenylcarbamate and 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-2-methylphenylcarbamate - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on potential concern identified by the registrant.
Sub-chronic toxicity (90 day): oral
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
Details
Alkenes, C13-14 - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Details
Alkenes, C13-14, hydroformylation products, low boiling - - Reproductive toxicity (two-generation reproductive toxicity) 29/07/2011 12/09/2011 Details
Alkenes, C6-8, even and odd, linear and branched - - Sub-chronic toxicity (90-day): oral 25/06/2012 09/08/2012 Details
Alkenes, C6-8, even and odd, linear and branched - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Details
alkoxy substituted aryl diazo heterocyclic aryl nitrile - - Genetic toxicity in vivo 31/01/2023 17/03/2023 Details
alkyl amine and alkylbenzenesulphonate - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Details
Aluminium tris(dialkylphosphinate) - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
23/06/2011
23/06/2011
08/08/2011
08/08/2011
Details
Amides, C18 (unsaturated) - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Details
Amides, C22 (unsaturated) - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Details
Amides, C8-18(even-numbered) and C18(unsatd.), N-(2-hydroxypropyl) - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Details
Bis(nonylphenyl)amine / Reaction products of Benzeneamine, N-phenyl- with nonene (branched) - -
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
28/02/2011
28/02/2011
14/04/2011
14/04/2011
Details
boron orthophosphate - 13308-51-5 Reproductive toxicity (pre-natal developmental toxicity) 30/06/2016 15/08/2016 Details
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distilled - -
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Details
Cashew, nutshell liq., oligomeric reaction products with 1-chloro-2,3-epoxypropane - 68413-24-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Details
Condensation products of triethanolamine with addition products of fatty acids, C18 (unsaturated) alkyl with maleic anhydride - -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/03/2017
10/03/2017
10/03/2017
25/04/2017
25/04/2017
25/04/2017
Details
Coupling reaction products of diazotized 2-amino-6-[(2-substituted ethyl)sulfonyl]naphthalene-1-subsituted acid with 4-({4-chloro-6-[ethyl(3-{[2-(substituted oxy)ethyl]sulfonyl}phenyl)amino]-heteromonocycl-2-yl}amino)-5-hydroxynaphthalene-2,7-disubstituted acid and their sodium and potassium salts - - 7.6.2 Mammalian erythrocyte micronucleus test according to OECD 474 03/12/2010 17/01/2011 Details
Disodium hydroxy-substituted alkanoate - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Details
Ethanaminium, 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethyl-, esters with C16-18 and C18 unsatd. fatty acids, chlorides - 1079184-43-2 Reproductive toxicity (two-generation reproductive toxicity) 26/04/2010 10/06/2010 Details
Ethoxypropyl-hydroxy-hexanamide - - Reproductive/developmental toxicity 04/12/2009 18/01/2010 Details
Fatty acids, C14-18 and C16-18-unsatd., maleated - 85711-46-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
11/11/2016
11/11/2016
11/11/2016
03/01/2017
03/01/2017
03/01/2017
Details
Halophosphate - - Sub-chronic toxicity (90 day): inhalation 15/07/2014 29/08/2014 Details
Hydrogenated oligomerisation product, including dimers and trimers, of tetradec-1-ene and alkene - -
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
10/08/2009
10/08/2009
24/09/2009
24/09/2009
Details
isliFe - - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 17/12/2019 31/01/2020 Details
N-benzyl-N-C16-18 (even numbered)-alkyl-N-methyl-C16-18 (even numbered)-alkyl-1-aminium chloride - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Details
Polar modified Rice Bran Wax - - Reproductive toxicity (pre-natal developmental toxicity) 03/05/2023 19/06/2023 Details
Poly(alkan-2-yl)heteropolycycle - - Genetic toxicity in vivo 31/01/2013 18/03/2013 Details
Polysulfo {5-hydroxy-1-naphthalen-2-yl-[4-[4-(2-sulfatoethyl-sulfonyl)-phenyl]diazenyl]-1H-pyrazole-3-carboxylic acid}, alkali metal salt - - Genetic toxicity in vivo 09/11/2009 24/12/2009 Details
Raffinates (Fischer-Tropsch), C10-25-branched - 1345668-40-7 Reproductive toxicity (two-generation reproductive toxicity) 17/08/2012 01/10/2012 Details
Reaction mass of disodium hydroxysulfinatoacetate and disodium hydroxysulfonatoacetate - -
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity study (90-day): oral
13/12/2010
13/12/2010
27/01/2011
27/01/2011
Details
Reaction mass of Poly(oxy-1,2-ethanediyl), ?-[2-[(2-hydroxyethyl)amino]-2-oxoethyl]-?-hydroxy-, mono-C13-15-alkyl ethers (odd numbered, branched and linear)-alkylethers, Acetamide, 2-(C13-15 (odd numbered, branched and linear)-alkyloxy)-N-(2-hydroxyethyl)- and Alcohols, C13-15-branched and linear - - Reproductive toxicity (pre-natal developmental toxicity) 16/08/2011 30/09/2011 Details
Reaction product of Distillates (petroleum), acid-treated heavy naphthenic and calcium oxide - - Reproductive toxicity (pre-natal developmental toxicity) 16/08/2011 30/09/2011 Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid - -
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
16/08/2011
16/08/2011
30/09/2011
30/09/2011
30/09/2011
30/09/2011
Details
Reaction products of anilinohydroxypolycyclicsulphonic acid coupled twice with diazotised aminonitrophenol, complexes with [3-hydroxy-4-[(2-hydroxy-1-polycyclic)azo]-7-nitropolycyclic-1-sulphonato(3-)]chromium, sodium salts - - Genetic toxicity in vivo 18/03/2021 03/05/2021 Details
Reaction products of Isophorone diamine, Butyl  glycidyl ether, and Bisphenol A diglicydyl ether - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Details
Silsesquioxanes, phenyl - 70131-69-0 Long-term toxicity to fish 18/09/2014 03/11/2014 Details
terpenic oligomers - - Reproductive toxicity (pre-natal developmental toxicity) 26/10/2022 12/12/2022 Details
Tris({[(hydroxyalkyl)amino]oxy}-oxoalkyl)-triazaalkanoic acid and water - - Reproductive toxicity (pre-natal developmental toxicity) 12/06/2013 29/07/2013 Details
3,3'-iminodi(propylamine) 200-261-2 56-18-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
Details
benzyltrimethylammonium chloride 200-300-3 56-93-9 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2014 17/03/2014 Details
Edetic acid 200-449-4 60-00-4 Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with_Na2H2EDTA (identifier not available) 16/06/2011 01/08/2011 Details
2-phenylethanol 200-456-2 60-12-8 Reproductive toxicity (two-generation reproductive toxicity) 15/04/2014 30/05/2014 Details
2-mercaptoethanol 200-464-6 60-24-2 Reproductive toxicity (pre-natal developmental toxicity) 15/04/2011 30/05/2011 Details
Diethyl ether 200-467-2 60-29-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 02/11/2018 17/12/2018 Details
diethyl ether 200-467-2 60-29-7 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
Androst-4-ene-3,17-dione 200-554-5 63-05-8 Long-term toxicity to fish 21/01/2021 08/03/2021 Details
Tetrasodium ethylenediaminetetraacetate 200-573-9 64-02-8 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
Hexanal 200-624-5 66-25-1 Genetic toxicity in vivo “|| Note: Testing proposal is based on concern identified by the registrant.” 27/05/2019 11/07/2019 Details
Dimethyl sulfoxide 200-664-3 67-68-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 31/01/2023 17/03/2023 Details
Mercaptoacetic acid 200-677-4 68-11-1 Long-term toxicity to fish 31/01/2023 17/03/2023 Details
cobalt di(acetate) 200-755-8 71-48-7
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
Details
Cobalt(II) diacetate 200-755-8 71-48-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Details
N,N'-diphenyl-p-phenylenediamine 200-806-4 74-31-7
Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
Ethylene 200-815-3 74-85-1
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
30/09/2021
30/09/2021
15/11/2021
15/11/2021
Details
Methylamine 200-820-0 74-89-5 Genetic toxicity in vivo 14/02/2011 31/03/2011 Details
Chloroethane 200-830-5 75-00-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
10/03/2017
10/03/2017
25/04/2017
25/04/2017
Details
2-chloropropane 200-858-8 75-29-6 Reproductive toxicity (two-generation reproductive toxicity) 16/05/2011 30/06/2011 Details
2-chloropropane 200-858-8 75-29-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Details
Nitromethane 200-876-6 75-52-5 Reproductive toxicity (pre-natal developmental toxicity) 04/04/2014 19/05/2014 Details
Tetramethylammonium chloride 200-880-8 75-57-0 Sub-chronic toxicity (90-day): oral 29/04/2014 13/06/2014 Details
Tetramethylammonium hydroxide 200-882-9 75-59-2 Sub-chronic toxicity (90-day): oral
// Note: testing proposed with Tetramethylammonium chloride (EC 200-880-8)
|| Note: Link to justification in the registration dossier not given as the information is confidential
27/01/2020 12/03/2020 Details
Tetramethylammonium hydroxide 200-882-9 75-59-2 Long-term toxicity to fish 30/06/2023 14/08/2023 Details
2-methylpropane-2-thiol 200-890-2 75-66-1
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with tert-dodecanethiol (EC no. 246-619-1 )
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with tert-dodecanethiol (EC no. 246-619-1)
22/09/2022
22/09/2022
07/11/2022
07/11/2022
Details
Pivalic acid 200-922-5 75-98-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/12/2017
20/12/2017
20/12/2017
05/02/2018
05/02/2018
05/02/2018
Details
Trichloroacetic acid 200-927-2 76-03-9 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
Trichloroacetic acid 200-927-2 76-03-9 Reproductive toxicity (pre-natal developmental toxicity) 14/10/2011 28/11/2011 Details
Perfluoroethane 200-939-8 76-16-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
Details
3a,4,7,7a-tetrahydro-4,7-methanoindene 201-052-9 77-73-6 Reproductive toxicity (pre-natal developmental toxicity) 28/02/2019 15/04/2019 Details
Trometamol 201-064-4 77-86-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-amino-1,3-propanediol
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-amino-1,3-propanediol
17/06/2014
17/06/2014
01/08/2014
01/08/2014
Details
tetraethylammonium hydroxide 201-073-3 77-98-5 Sub-chronic toxicity (90-day): oral || Note: testing proposed with N,N,N-trimethylmethanaminium chloride (EC 200-880-8; CAS 75-57-0) 30/09/2015 16/11/2015 Details
Propylidynetrimethanol 201-074-9 77-99-6 Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed on rabbits 16/05/2014 30/06/2014 Details
Propylidynetrimethanol 201-074-9 77-99-6 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2011 30/06/2011 Details
Tetraethyllead 201-075-4 78-00-2 Sub-chronic toxicity study (90-day) 01/07/2011 15/08/2011 Details
Triethoxy(vinyl)silane 201-081-7 78-08-0
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Details
1-ethynylcyclohexanol 201-100-9 78-27-3 Sub-chronic toxicity (90-day): oral 18/02/2014 04/04/2014 Details
Diethyl ethylphosphonate 201-111-9 78-38-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
tris(2-butoxyethyl) phosphate 201-122-9 78-51-3 Reproductive toxicity (two-generation reproductive toxicity) 01/07/2011 15/08/2011 Details
Tris(2-butoxyethyl) phosphate 201-122-9 78-51-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Details
di-tert-butyl 1,1,4,4-tetramethyltetramethylene diperoxide 201-128-1 78-63-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/10/2011
14/10/2011
28/11/2011
28/11/2011
Details
2,2'-dimethyl-2,2'-azodipropiononitrile 201-132-3 78-67-1 Reproductive toxicity (pre-natal developmental toxicity) 03/02/2016 21/03/2016 Details
2,2'-dimethyl-2,2'-azodipropiononitrile 201-132-3 78-67-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/03/2011
15/03/2011
15/03/2011
29/04/2011
29/04/2011
29/04/2011
Details
Linalool 201-134-4 78-70-6 Reproductive toxicity (pre-natal developmental toxicity) 01/07/2021 16/08/2021 Details
2-methylpropan-1-ol 201-148-0 78-83-1 Long-term toxicity to fish ||Note: testing proposed with Propan-1-ol (EC no. 200-746-9) ||Note: testing proposed with Pentan-1-ol (EC no. 200-752-1) 26/10/2022 12/12/2022 Details
Propylenediamine 201-155-9 78-90-0 Reproductive toxicity (pre-natal developmental toxicity) 16/12/2020 01/02/2021 Details
1-aminopropan-2-ol 201-162-7 78-96-6 Reproductive toxicity (pre-natal developmental toxicity) 17/09/2019 01/11/2019 Details
Chloroacetic acid 201-178-4 79-11-8 Reproductive toxicity (pre-natal developmental toxicity) 14/10/2011 28/11/2011 Details
Chloroacetic acid 201-178-4 79-11-8 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
Peracetic acid 201-186-8 79-21-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/08/2021
26/08/2021
11/10/2021
11/10/2021
Details
Nitroethane 201-188-9 79-24-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with nitromethane (EC 200-876-6) 10/03/2017 25/04/2017 Details
2,5-di-tert-pentylhydroquinone 201-222-2 79-74-3 Sub-chronic toxicity (90-day): oral 31/05/2011 15/07/2011 Details
Camphene 201-234-8 79-92-5 Sub-chronic toxicity (90-day): oral 24/02/2020 09/04/2020 Details
4,4'-isopropylidenedi-o-cresol 201-240-0 79-97-0 Genetic toxicity in vivo 25/05/2020 09/07/2020 Details
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Long-term toxicity to fish 17/06/2014 01/08/2014 Details
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Reproductive toxicity (pre-natal developmental toxicity) 06/09/2018 22/10/2018 Details
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Genetic toxicity in vivo 16/12/2020 01/02/2021 Details
bis(4-chlorophenyl) sulphone 201-247-9 80-07-9
Bioaccumulation: terrestrial
Reproductive toxicity (pre-natal developmental toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Details
Bis(4-chlorophenyl) sulphone 201-247-9 80-07-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Details