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Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Distillates (petroleum), hydrodesulfurized middle 265-183-3 64742-80-9 Genetic toxicity in vivo 14/05/2020 29/06/2020
Distillates (petroleum), hydrotreated middle 265-148-2 64742-46-7 Genetic toxicity in vivo 14/05/2020 29/06/2020
Gas oils (petroleum), hydrodesulfurized 265-182-8 64742-79-6 Genetic toxicity in vivo 14/05/2020 29/06/2020
Benzyldimethylamine 203-149-1 103-83-3
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
23/03/2020
23/03/2020
23/03/2020
07/05/2020
07/05/2020
07/05/2020
(octahydro-4,7-methano-1H-indenediyl)bis(methylene) diacrylate 255-901-3 42594-17-2
Reproductive toxicity (pre-natal developmental toxicity)
Bioaccumulation test (Bioconcentration: Flow-through Fish Test)
23/03/2020
23/03/2020
07/05/2020
07/05/2020
4-(1,1-dimethylethyl)cyclohexyl acrylate 282-104-8 84100-23-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
23/03/2020
23/03/2020
07/05/2020
07/05/2020
N,N''-(4-methyl-m-phenylene)bis[N',N'-dimethylurea] 241-523-6 17526-94-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
23/03/2020
23/03/2020
07/05/2020
07/05/2020
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid 931-291-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
23/03/2020
23/03/2020
07/05/2020
07/05/2020
(Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid 701-116-0 - Reproductive toxicity (pre-natal developmental toxicity) 23/03/2020 07/05/2020
1,4-bis(2,3-epoxypropoxy)butane 219-371-7 2425-79-8 Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane (1:2) (EC 618-939-5) 23/03/2020 07/05/2020
2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate 224-116-8 4203-89-8 Genetic toxicity in vivo 23/03/2020 07/05/2020
2-[[(butylamino)carbonyl]oxy]ethyl acrylate 264-036-0 63225-53-6 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 23/03/2020 07/05/2020
2-isocyanatoethyl methacrylate 250-284-7 30674-80-7 Reproductive toxicity (pre-natal developmental toxicity) 23/03/2020 07/05/2020
4-phenylbutenone 204-555-1 122-57-6 Genetic toxicity in vivo 23/03/2020 07/05/2020
Dialkyl-methyl-dihydro-heteropolycyle 815-131-6 913171-06-9 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/03/2020 07/05/2020
Dimethyl (p-methoxybenzylidene)malonate 231-185-8 7443-25-6 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 23/03/2020 07/05/2020
Dioctyltin dilaurate 222-883-3 3648-18-8 Reproductive toxicity (pre-natal developmental toxicity) 23/03/2020 07/05/2020
Reaction products of 2-hydroxyethyl methacrylate and diphosphorus pentaoxide 810-703-1 1187441-10-6 Genetic toxicity in vivo 23/03/2020 07/05/2020
tert-butyl perbenzoate 210-382-2 614-45-9 Long-term toxicity to fish 23/03/2020 07/05/2020
(1S)-1,5-anhydro-2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol 695-878-0 1283129-18-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
24/02/2020
24/02/2020
09/04/2020
09/04/2020
2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-α-D-glucopyranosyl bromide 686-241-8 81058-27-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
24/02/2020
24/02/2020
09/04/2020
09/04/2020
Dibutyl itaconate 218-451-9 2155-60-4
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
24/02/2020
24/02/2020
09/04/2020
09/04/2020
Etocrilene 226-029-0 5232-99-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
24/02/2020
24/02/2020
09/04/2020
09/04/2020
Fluorobenzene 207-321-7 462-06-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
24/02/2020
24/02/2020
09/04/2020
09/04/2020
N,N,2,8-tetramethyl-5,11-dioxa-2,8-diazatridecan-13-amine 695-748-3 65286-55-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
24/02/2020
24/02/2020
09/04/2020
09/04/2020
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide 806-543-7 215917-77-4
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
24/02/2020
24/02/2020
09/04/2020
09/04/2020
reaction products of benzaldehyde diethylenetriamine and triethylenetetramine, hydrogenated 846-447-2 1219458-07-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
24/02/2020
24/02/2020
09/04/2020
09/04/2020
1,1'-(ethane-1,2-diyl)bis[pentabromobenzene] 284-366-9 84852-53-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 24/02/2020 09/04/2020
1,4-phenylenebis[(4-phenoxyphenyl)methanone] 620-097-9 54299-17-1 Bioaccumulation test in Fish, Reproductive toxicity (pre-natal developmental toxicity) 24/02/2020 09/04/2020
3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate 261-665-2 59219-71-5 Sub-chronic toxicity (90-day): oral 24/02/2020 09/04/2020
4-tert-butylcyclohexyl acetate 250-954-9 32210-23-4 Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with cis-4-tert-butylcyclohexyl acetate
24/02/2020 09/04/2020
Camphene 201-234-8 79-92-5 Sub-chronic toxicity (90-day): oral 24/02/2020 09/04/2020
2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 260-829-0 57583-35-4
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
Poly(oxy-1,2-ethanediyl), α-butyl-ω-hydroxy- 500-012-0 9004-77-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1).
Reproductive toxicity (pre-natal developmental toxicity) – rats-
|| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)
Reproductive toxicity (pre-natal developmental toxicity) – rabbits
|| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
Reaction products of monoethanolamine and boric acid (1:1) 701-025-6 -
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0)
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0)
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0)
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
Reaction products of monoethanolamine and boric acid (1:3) 701-024-0 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
1,1'-[[3-(dimethylamino)propyl]imino]bispropan-2-ol 264-261-4 63469-23-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
12/03/2020
12/03/2020
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol 212-985-6 901-44-0
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
12/03/2020
12/03/2020
3-[[3-[[(2-cyanoethyl)amino]methyl]-3,5,5-trimethylcyclohexyl]amino]propiononitrile 300-496-1 93940-97-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Diethyl ethylphosphonate 201-111-9 78-38-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
12/03/2020
12/03/2020
N,N'-diphenyl-p-phenylenediamine 200-806-4 74-31-7
Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Reaction products of orthoboric acid with 2,2'-iminodiethanol (1:1) 701-083-2 -
"Reproductive toxicity (pre-natal developmental toxicity)
“||Note: testing proposed with MEA Polyborate (EC 701-025-6)”
Sub-chronic toxicity (90-day): oral “||Note: testing proposed with MEA Polyborate (EC 701-025-6)”
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Sodium salts of [hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid (4-7 Na:1) 947-369-2 -
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1

|| Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1

|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020
27/01/2020
12/03/2020
12/03/2020
tetrahydro-2-methylfuran 202-507-4 96-47-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
27/01/2020
27/01/2020
12/03/2020
12/03/2020
1-imino-1H-isoindol-3-amine 222-426-8 3468-11-9 Genetic toxicity in vivo 27/01/2020 12/03/2020
2-(2-(2-butoxyethoxy)ethoxy)ethanol 205-592-6 143-22-6 Reproductive toxicity (pre-natal developmental toxicity):
1st PNDT on the registered substance
2nd PNDT with the registered substance
// Note: Testing proposal for an EOGRTS proposed to be conducted with the analogue substance 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1, CAS 112-35-6)
27/01/2020 12/03/2020
4,4'-[(isopropylidene)bis(p-phenyleneoxy)]diphthalic dianhydride 253-781-7 38103-06-9 Sub-chronic toxicity (90-day): oral 27/01/2020 12/03/2020
4,4'-methylenebis[N-sec-butylaniline] 226-122-6 5285-60-9 Bioaccumulation aquatic / sediment 27/01/2020 12/03/2020
4-chloroformylphthalic anhydride 214-874-8 1204-28-0 Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020 12/03/2020
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate 220-482-8 2781-11-5 Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020 12/03/2020



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