Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
Reaction mass of tetrasodium (E)-7-((4-(4-chloro-6-(3-(2-(sulfooxy)ethylsulfonyl)phenylamino)-1,3,5-triazin-2-ylamino)-2-ureidophenyl)diazenyl)naphthalene-1,3,6-trisulfonate and (E)-7-((4-(4-chloro-6-(3-(2-(sulfooxy)ethylsulfonyl)phenylamino)-1,3,5-triazin-2-ylamino)-2-ureidophenyl)diazenyl)naphthalene-1,3,6-trisulfonic acid
EC number: 945-219-0 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 > 1000 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1 000 mg/L
Additional information
There are no experimental available data of the target substance, thus the information on the Similar Substance 04 has been taken into account. The structural differences occurring between the target substance and Similar Substance 04 are not expected to significantly impact the toxicity to aquatic invertebrates, thus the read across approach can be considered as representavive and appropriate (details in the document attached to the IUCLID section 13).
The study on acute toxicity to daphnids with the structural analogue meets the requirements of EEC Directive 79/831 Annex V Methods for the determination of ecotoxicity 5.1.2 Acute toxicity for daphnia and the OECD Guidelines for Testing of Chemicals, Section 2 - Effects on biotic systems 202 Daphnia sp., 14-day reproduction test (including an acute immobilisation test). Study conducted in compliance with GLP.
Testing for acute toxicity in Daphnia magna (water flea) over a total of 48 hours yielded the following immobility values:
|
after 24 hours (mg/L) |
after 48 hours (mg/L) |
EC0 |
≥ 1000 |
560 |
EC50 |
> 1000 |
> 1000 |
The concentrations tested were 0, 560, and 1000 mg/L. Immobility was observed at 1000 mg/L.
The test batches were present as red solutions. No segregation or formation of precipitates could be observed.
In order to determine the substance concentration, water samples were taken at the end of the study. All mean values were above 80% of the nominal concentration.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
