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Diss Factsheets
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EC number: 939-946-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50(72h) = 1.08 mg/L, NOEC = 0.111 mg/L, Chlorella vulgaris Beij., Zhen (2016)
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1.08 mg/L
- EC10 or NOEC for freshwater algae:
- 0.111 mg/L
Additional information
The screening study from Rudolf (2011) was not considered. There is insufficient detail in the report to assess the reliability of these results.The screening studies' results are not reliable or adequate for the purposes of risk assessment or classification.
The study from Zhen (2016) was designed to determine the toxicity of test substance to algae (Chlorella vulgaris Beij.), according to "The guidelines for the testing of chemicals" (HJ/T 153-2004), with reference to OECD 201, and is considered to be the key study and is assigned reliability rating Klimisch 2. The EC50(72) of test item was 1.08 mg/L and the NOEC 0.111 mg/L.
The key study was not performed under OECD GLP, as it was carried out for registration purposes outside the European Economic Area, and does not meet the requirements of Article 13(4). However, the data is considered to be equivalent by meeting the criteria set out in Annex XI, 1.1.2:
1. The key study test data is adequate for the purposes of classification and risk assessment. Algae are not the most sensitives species and do not drive classification or risk assessment, and the substance is classified as the worst-case for aquatic toxicity (Category 1).
2. The key parameters forseen to be investigated have been adequately and reliably covered. The study design is equivalent to OECD 201, and it was carried out under a national quality assurance scheme.
3. The study exposure period of 72h is that required by the OECD guideline method.
4. Adequate and reliable documentation of the study is available in a full study report.
The data provided for this endpoint is considered to be relevant, adequate, reliable and complete for the purposes of classification and risk assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.