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Diss Factsheets
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EC number: 249-978-2 | CAS number: 29964-84-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- OECD 105, GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- (1995)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Key result
- Water solubility:
- 199 µg/L
- Temp.:
- 20 °C
- pH:
- 8
- Remarks on result:
- other: The limit of quantification of the analytical method was fixed at 100 µg/L.
- Water solubility:
- 155 µg/L
- Temp.:
- 30 °C
- pH:
- 8
- Remarks on result:
- other: The limit of quantification of the analytical method was fixed at 100 µg/L.
- Conclusions:
- Interpretation of results: slightly soluble (0.1-100 mg/L)
In a valid guideline study (OECD 105, with GLP) using the columns elution method the solubility of in water was determined to be 199 µg/L at 20 °C and 155 µg/L at 30 °C. The pH value of all test solutions was 8. So the test substance is considered to be slightly soluble. No temperature dependence of the water solubility was observed. - Executive summary:
In a valid guideline study (OECD 105, with GLP) using the columns elution method the solubility of in water was determined to be 199 µg/L at 20 °C and 155 µg/L at 30 °C. The pH value of all test solutions was 8.
Analyses were performed by HPLC-UV on a reversed-phase column (C 18) with online extraction against an external standard. The method was validated with satisfactory results with respect to linearity, accuracy, precision and specificity. The pH values of the samples were measured with special indicator sticks. All samples were checked negative for colloidal material by measuring of the Tyndall effect.
So the test substance is considered to be slightly soluble. No temperature dependence of the water solubility was observed.
NOTE: Any of data in this dataset are disseminated by the European Union on a right-to-know basis and this is not a publication in the same sense as a book or an article in a journal. The right of ownership in any part of this information is reserved by the data owner(s). The use of this information for any other, e.g. commercial purpose is strictly reserved to the data owners and those persons or legal entities having paid the respective access fee for the intended purpose.
Reference
Description of key information
Water solubility of Isodecyl methacrylate: 199 µg/L at 20°C, pH8, Lange 2009,
OECD 105 (column elution method), GLP.
Key value for chemical safety assessment
- Water solubility:
- 199 µg/L
- at the temperature of:
- 20 °C
Additional information
The key study (Lange, 2009) reports a water solubility value for Isodecyl methacrylate of 199 µg/L at 20°C. Even a very low solubility of Isodecyl methacrylate was calculated (0.378 mg/L at 25 °C) with the valid calculation method for IDMA using EpiWin version 4.00 (Evonik Röhm GmbH, 2011).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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