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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
- Short-term toxicity to aquatic invertebrates: The 48 h LC50 of zinc (Zn2+) in Daphnia magna was 0.799 mg/L in a flow-through experiment. This corresponds to a 48-h LC50 of 3.11 mg zinc monoglycinate sulfate monohydrate/L in Daphnia magna.
- Toxicity to aquatic algae and cyanobacteria: The average 72-h EC50 of zinc was 0.133 mg Zn2+/L in Pseudokirchneriella subcapitata. This corresponds to a 72-h EC50 of 0.52 mg zinc monoglycinate sulfate monohydrate/L in Pseudokirchneriella subcapitata.
Additional information
The zinc 48-h EC50 or LC50 for aquatic invertebrates (Daphnia magna) was determined in various studies. The LC50 value chosen in this approach is 0.799 mg Zn2+/L according to Attar and Maly (1982), for the following reasons: the reported 48-h EC50 values in the most reliable studies (RL2) range from 0.799 to 6.03 mg Zn2+/L. The well documented studies by Attar and Maly (1982) and Heijerick et al. (2002) report 48-h values of 0.799 (LC50) and 0.93 mg Zn2+/L (EC50), respectively, which are in a very close range. For precautionary reasons, the more conservative value was chosen.
Apart from effect concentrations, Park et al. (2019) as well as Ergönül et al. (2012) report adverse effects of Zn2+ on Daphnia magna like internal injuries, lethargy, corrosion in the carapax and partial ruptures. The 48 -h LC50 value chosen in this approach is 0.799 mg Zn2+/L. This corresponds to a 48-h LC50 of 3.11 mg zinc monoglycinate sulfate monohydrate/L in Daphnia magna.
The zinc EC50 for aquatic algae were determined in various studies. The reported 72- or 96-h EC50 values in reliable studies range from 0.08 to 2.432 mg Zn2+/L. The zinc toxicity in green algae was shown to be strongly dependent on the examined species. The most sensitive species was Pseudokirchneriella subcapitata (72-h EC50: 0.133 mg Zn2+/L), while Ankistrodesmus falcatus (96-h EC50: 2.432 mg Zn2+/L), Chlorella vulgaris (96-h EC50: 2.4 mg Zn2+/L) and Desmodesmus subspicatus (96-h EC50: 2.258 mg Zn2+/L) were less sensitive.
The EC50 value chosen in this approach is 0.133 mg Zn2+/L according to De Schamphelaere et al. (2004) for the following reasons: the study reported by De Schamphelaere et al. (2004) was conducted according to OECD guideline 201 (RL1) using the sensitive species Pseudokirchneriella subcapitata, for regular 72 hours. In the other studies using Pseudokirchneriella subcapitata by Al-Hasawi et al.(2020) and Rojíčková-Padrtová and Maršálek (1999), no guideline was followed and the study duration was 96 h.
The 72-h EC50 value chosen in this approach is 0.133 mg Zn2+/L. This corresponds to a 72-h EC50 of 0.52 mg zinc monoglycinate sulfate monohydrate/L in Pseudokirchneriella subcapitata.
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