Registration Dossier
Registration Dossier
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EC number: 209-513-6 | CAS number: 583-60-8
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 969
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 403 (Acute Inhalation Toxicity)
- Principles of method if other than guideline:
- No description of the guideline available
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-methylcyclohexanone
- EC Number:
- 209-513-6
- EC Name:
- 2-methylcyclohexanone
- Cas Number:
- 583-60-8
- Molecular formula:
- C7H12O
- IUPAC Name:
- 2-methylcyclohexan-1-one
- Test material form:
- liquid
- Details on test material:
- As received, undiluted, the sample was observed to be a free-flowing
clear liquid.
Constituent 1
Test animals
- Species:
- rat
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation: vapour
- Type of inhalation exposure:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 2 800 ppm
- Based on:
- test mat.
- Exp. duration:
- 4 h
- Mortality:
- 50%
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Conclusions:
- 2-methycyclohexanone has an acute inhalative LC50 of 2800 ppm. As a result, the substance meets the criteria for classification for Category 4 according to Regulation (EC) No 1272/2008, Annex I section 3.1.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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