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Diss Factsheets
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EC number: 701-315-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: screening test, other
- Remarks:
- (Q)SAR model
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Justification for type of information:
- 1. SOFTWARE: Biowin – Ready biodegradation model
2. MODEL: Biowin v4.10 [EPISuite v4.11]
3. SMILES OR OTHER IDENTIFIERS USED AS INPUT FOR THE MODEL: SMILES: C=C[Si](O[Si](C=C)(C)C)(C)C
4. SCIENTIFIC VALIDITY OF THE (Q)SAR MODEL
QMRF and QPRF attached in IUCLID. - Principles of method if other than guideline:
- The Biodegradation Probability Program (Biowin) estimates the probability for the rapid aerobic biodegradation of an organic chemical in the presence of mixed populations of environmental microorganisms. Estimates are based upon fragment constants that were developed using multiple linear and non-linear regression analyses.
- GLP compliance:
- no
- Specific details on test material used for the study:
- Estimation conducted based on the following data:
CHEMICAL NAME: Disiloxane, 1,3-diethenyl-1,1,3,3-tetramethyl-
MOLECULAR FORMULA: C8 H18 O1 Si2
MOLECULAR WEUGHT : 186.40 - Oxygen conditions:
- other: Not applicable
- Inoculum or test system:
- other: Not applicable
- Details on inoculum:
- Not applicable
- Preliminary study:
- Not applicable
- Details on results:
- Ready Biodegradability Prediction: NO based on the following predictions
Biowin1 (Linear Model Prediction): 0.6588
Biowin2 (Non-Linear Model Prediction): 0.5895
Biowin3 (Ultimate Biodegradation Timeframe): 2.7872
Biowin4 (Primary Biodegradation Timeframe): 3.5788
Biowin5 (MITI Linear Model Prediction): 0.1964
Biowin6 (MITI Non-Linear Model Prediction): 0.0687
Biowin7 (Anaerobic Model Prediction): 0.0767 - Conclusions:
- The substance is a solution of an inorganic salt and the biodegradability is considered to be relevant only to the organic component. The organic component, 1,3-divinyl-1,1,3,3-tetramethyldisiloxane, is considered not readily biodegradable.
- Executive summary:
The substance is a solution of an inorganic salt and the biodegradability is considered to be relevant only to the organic component. The biodegradability of the organic component, 1,3 -divinyl-1,1,3,3 -tetramethyldisiloxane, is taken from Biowin, a reliable, peer-reviewed QSAR prediction model (USEPA 2010). 1,3-divinyl-1,1,3,3-tetramethyldisiloxane is considered not readily biodegradable.
- Endpoint:
- biodegradation in water: ready biodegradability
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- the study does not need to be conducted because the substance is inorganic
Referenceopen allclose all
Predictions from Biowin models:
Biowin1 (Linear Model Prediction): Biodegrades Fast
Biowin2 (Non-Linear Model Prediction): Biodegrades Fast
Biowin3 (Ultimate Biodegradation Timeframe): Weeks
Biowin4 (Primary Biodegradation Timeframe): Days-Weeks
Biowin5 (MITI Linear Model Prediction): Not Readily Degradable
Biowin6 (MITI Non-Linear Model Prediction): Not Readily Degradable
Biowin7 (Anaerobic Model Prediction): Does Not Biodegrade Fast
Description of key information
Biodegradation is not relevant for inorganic substances and this substance is a solution of an inorganic salt. Therefore, only the biodegradability of the organic component of this substance is reported. The organic component, 1,3-diethenyl-1,1,3,3-tetramethyldisiloxane, is predicted to be not readily biodegradable.
Key value for chemical safety assessment
Additional information
Biodegradation is not relevant for inorganic substances and this substance is a solution of an inorganic salt. Therefore, only the biodegradability for the organic component of this substance is reported. The biodegradability of the organic component, 1,3-diethenyl-1,1,3,3-tetramethyldisiloxane, is taken from Biowin, a reliable, peer-reviewed QSAR prediction model (USEPA 2010). The organic component, 1,3-diethenyl-1,1,3,3-tetramethyldisiloxane is predicted to be not readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.