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EC number: 279-255-7 | CAS number: 79770-29-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012-11-22 to 2012-11-24 (exposure period)
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study with analytical monitoring
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Details on sampling:
- - Sampling method: The samples of fresh water solution at the test initiation and the samples of spent water solution at test termination were analysed in order to determine the contents of the test substance in the test solution.
- Sample preparation for analysis: A water sample in a volume of 10 - 200 mL (i.e. control sample, test sample, sample fortified with the standard) was evaporated to dryness at 100°C using a vacuum rotary evaporator. The dry residue was redissolved in a suitable amount of water and analyzed spectrophotometrically. - Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: After thoroughly mixing 500.3 mg of the test item was filled up to 50.0 mL of Elendt Medium (M 7). After mixing by hand a homogeneous solution was obtained. The solution was mixing by hand thoroughly and used to prepare the test concentration 120 mg/L. 18 mL were pipetted into a volumetric flask with the Elendt Medium and filled up to 1500 mL. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: water flea
- Source: Standard Iabaratory culture maintained at the Institute of lndustrial Organic Chemistry, Branch Pszczyna, Department of Ecotoxicology, Labaratory of Aquatic Toxicology
- Age at study initiation: Up to 24 hours
- Method of breeding: Parthenogenetical reproduction
- Feeding during test: none
- Type and amount of food during culturing: The daphnids were fed with Pseudokirchneriella subcapitata algae suspension originating from the culture at the Labaratory of Aquatic Toxicology, Group B vitamins and micronutrients necessary for proper growth werr supplied with lyophilized Spirulin sp. suspension - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Test temperature:
- 19.9 – 20.4°C
- pH:
- 7.52 – 7.55 (control)
- Dissolved oxygen:
- 8.6 – 9.6 mg/L
- Nominal and measured concentrations:
- Nominal concentration: 120 mg/L
Measured concentrations: At test initiation 98.20% of and at test termination 100.09% of the nominal concentration (mean values). - Details on test conditions:
- TEST SYSTEM
- Test vessel: Glass beakers of 150 mL capacity covered with transparent Iids in order to minimize evaporation and to prevent accidental contamination
- Fill volume: 100 mL
- Aeration: none
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 8
- No. of vessels per control (replicates): 8
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: According to guideline
- Intervals of water quality measurement: at test start and at test termination
OTHER TEST CONDITIONS
- Photoperiod: light: dark ratio of 16 h: 8 h
EFFECT PARAMETERS MEASURED: Mobility
TEST CONCENTRATIONS
- Range finding study
- Test concentrations: 0.1; 1.0; 10.0 and 100.0 mg/L (nominal values)
- Results used to determine the conditions for the definitive study: yes - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 120 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: Concentration analytically verified
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 120 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: Concentration analytically verified
- Details on results:
- - Mortality of control: none
- Any observations (e.g. precipitation) that might cause a difference between measured and nominal values: no
- Effect concentrations exceeding solubility of substance in test medium: no - Results with reference substance (positive control):
- - Results with reference substance valid? Yes
- EC50/LC50: The EC50 (24 h) value was 1.77 mg/L and the EC50 (48 h) value was 0.61 mg/L - Validity criteria fulfilled:
- yes
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Read-across justification in section 13 of IUCLID.
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Details on sampling:
- - Sampling method: The samples of fresh water solution at the test initiation and the samples of spent water solution at test termination were analysed in order to determine the contents of the test substance in the test solution.
- Sample preparation for analysis: A water sample in a volume of 10 - 200 mL (i.e. control sample, test sample, sample fortified with the standard) was evaporated to dryness at 100°C using a vacuum rotary evaporator. The dry residue was redissolved in a suitable amount of water and analyzed spectrophotometrically. - Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: After thoroughly mixing 500.3 mg of the test item was filled up to 50.0 mL of Elendt Medium (M 7). After mixing by hand a homogeneous solution was obtained. The solution was mixing by hand thoroughly and used to prepare the test concentration 120 mg/L. 18 mL were pipetted into a volumetric flask with the Elendt Medium and filled up to 1500 mL. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: water flea
- Source: Standard Iabaratory culture maintained at the Institute of lndustrial Organic Chemistry, Branch Pszczyna, Department of Ecotoxicology, Labaratory of Aquatic Toxicology
- Age at study initiation: Up to 24 hours
- Method of breeding: Parthenogenetical reproduction
- Feeding during test: none
- Type and amount of food during culturing: The daphnids were fed with Pseudokirchneriella subcapitata algae suspension originating from the culture at the Labaratory of Aquatic Toxicology, Group B vitamins and micronutrients necessary for proper growth werr supplied with lyophilized Spirulin sp. suspension - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Test temperature:
- 19.9 – 20.4°C
- pH:
- 7.52 – 7.55 (control)
- Dissolved oxygen:
- 8.6 – 9.6 mg/L
- Nominal and measured concentrations:
- Nominal concentration: 120 mg/L
Measured concentrations: At test initiation 98.20% of and at test termination 100.09% of the nominal concentration (mean values). - Details on test conditions:
- TEST SYSTEM
- Test vessel: Glass beakers of 150 mL capacity covered with transparent Iids in order to minimize evaporation and to prevent accidental contamination
- Fill volume: 100 mL
- Aeration: none
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 8
- No. of vessels per control (replicates): 8
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: According to guideline
- Intervals of water quality measurement: at test start and at test termination
OTHER TEST CONDITIONS
- Photoperiod: light: dark ratio of 16 h: 8 h
EFFECT PARAMETERS MEASURED: Mobility
TEST CONCENTRATIONS
- Range finding study
- Test concentrations: 0.1; 1.0; 10.0 and 100.0 mg/L (nominal values)
- Results used to determine the conditions for the definitive study: yes - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 120 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: Concentration analytically verified
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 120 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: Concentration analytically verified
- Details on results:
- - Mortality of control: none
- Any observations (e.g. precipitation) that might cause a difference between measured and nominal values: no
- Effect concentrations exceeding solubility of substance in test medium: no - Results with reference substance (positive control):
- - Results with reference substance valid? Yes
- EC50/LC50: The EC50 (24 h) value was 1.77 mg/L and the EC50 (48 h) value was 0.61 mg/L - Validity criteria fulfilled:
- yes
- Conclusions:
- NOEC and EC50 >120 mg/L
Referenceopen allclose all
Description of key information
With high probability acutely not harmful to aquatic invertebrates.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 120 mg/L
Additional information
The acute toxicity of the test substance on Daphnia magna was investigated in a GLP guideline study according to OECD 202. In this limit test, no toxic effects on the test organisms were observable at an analytically verified concentration of 120 mg/L (BASF SE 50E0861/11X413, 2012). Hence, the test substance is not considered to be acutely harmful to aquatic invertebrates.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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