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Diss Factsheets
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EC number: 932-833-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 1.35 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.8 mg/L
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 5 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 46 mg/kg food
- Assessment factor:
- 30
Additional information
PNECaquatic
A short-term toxicity study with invertebrates is available with the registered substance in which no effects were reported at the highest concentration tested (100 mg/l). The ammonia toxicity was expected to contribute to the toxicity of the study and an EC50in the range 10-100 mg/l at pH 8 with the registered substance was expected from the presence of ammonia. Therefore it is not possible to derive a PNEC based on this study.
In the study report a range finding test was conducted with ferric citrate in which no effects were reported up to 100 mg/l. Therefore it is also not possible to derive a meaningful PNEC for ferric citrate.
The substance is expected to dissociate in solution therefore PNECs for each constituent are considered separately.
Iron
Any concentration of iron in water that can be considered as stable can only be due to the complexing effects of natural constituents in the water. The amount of complexed iron in water will already be at saturation and the saturation concentration will vary with location. It is not realistically possible to consider that any further addition of iron to the aquatic compartment will increase the stable complexed concentration and therefore no PNEC can be set for water.
Citric acid
Citric acid is a metabolic intermediate vital to the TCA respiration pathway found in all animal and plant cells. It is also found in appreciable steady state levels in animals and in even higher amounts in plants, with actual levels being influenced by rates of respiration and photosynthesis. There is little evidence for deleterious effects even with large doses. As a consequence it is not appropriate to derive PNEC values for citric acid.
Ammonia
A PNECaqua(freshwater) for ammonia has been derived by the UK Environment Agency for the purpose of setting an Environmental Quality Standard (EQS) under Annex VIII of the Water Framework Directive (WFD). A PNEC of 0.0011 mg NH3/L is equivalent to 0.20 mg ammonia/ammonium/l at pH 7. This is equivalent to a loading in 1.35 mg/l of the registered substance at pH 7 and 0.14 mg/L of FAC at pH 8. In reality, the PNEC in terms of total loading would vary significantly according to test conditions.
The lowest reliable NOEC for long-term effects of ammonia on marine biota is 0.066 mg NH3-N l-1 for growth of Dover sole (Solea solea). Short-term test data are available that indicate this may not be the most sensitive taxonomic group (molluscs and echinoderms are more sensitive following acute exposure) and so an assessment factor of 100 is recommended to protect these taxa, resulting in a PNECaqua(marine water)of 0.66 μg/l un-ionised ammonia (EA 2007). At pH 7.0, this is equivalent to 0.12 mg ammonia/ammonium/l.This is equivalent to a loading in 0.8 mg/l of the registered substance at pH 7 and 0.08 mg/l of the registered substance at pH 8. In reality, the PNEC in terms of total loading would vary significantly according to test conditions.
Conclusion on classification
Reaction mass of ammonium iron (III) citrate and ammonium sulfate will dissociate in solution to form citric acid, ammonium and iron.
Since the ammonia fraction of ammonium sulfate is considered to be the most toxic part of the substance, the registered substance is conservatively classified based on this substance.
Ammonia is an inorganic substance and based on the short-term toxicity data available (EC/LC50 0.76 mg NH3/l for fish, equivalent to 100 mg/l of the registered substance at pH 8) the registered substance should not be classified for aquatic Acute effects in the EU according to the Regulation (EC) No. 1272/2008.
At a loading rate of 100 mg/l the registered substance in solution at pH 8 (worst case) would produce 0.77 mg NH3/l.
Based on long-term toxicity data the lowest NOEC is 0.004 mg un-ionised NH3/l for invertebrates, equivalent to 0.57 mg/l of the registered substance, which indicates that the substance is classified as Chronic Category 2 for the environment since the citric acid fraction of the substance is considered to be rapidly degradable for the environment in the EU according to the Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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