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EC number: 236-400-9 | CAS number: 13351-61-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The aquatic toxicity of the read across substance 2,2-Dimethyl-3-(3-methylphenyl)-propanol to the unicellular freshwater green alga Scenedesmus subspicatus was determined. The NOEC was 7.2 mg/L (inhibition of biomass growth and inhibition of growth rate). The EC50-values for inhibition of biomass growth (EbC50) and specific growth rate (ErC50) were 19 and 27 mg/L, respectively.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 27 mg/L
- EC10 or NOEC for freshwater algae:
- 7.2 mg/L
Additional information
A read across approach was applied for short-term toxicity to aquatic invertebrates using data of 2,2-Dimethyl-3-(3-methylphenyl)-propanol (CAS 103694 -68 -4) as this substance was considered to show similar ecotoxicological properties as compared to the test item. For further justification please refer to IUCLID section 13.
The aquatic toxicity of the read across substance 2,2-Dimethyl-3-(3-methylphenyl)-propanol to the unicellular freshwater green algae Scenedesmus subspicatus was determined according to the principles of OECD-Guideline 201. The study was conducted under static conditions over a duration of 72 hours with an initial cell density of nominally 10^4 cells/mL. 5 concentration levels were tested in a geometrical series with a dilution factor of 2: nominal: 6.25 - 12.5 - 25 - 50 - 100 mg/L corresponding to overall mean measured concentrations: 7.2 - 15 - 31 - 64 - 131 mg/L. 3 replicates were tested for each concentration level and 6 replicates for control. The concentrations of the read across substance were determined from all freshly prepared media after 0 h and from old media after 72 h via GC/MS. All effect levels were given based on the mean measured concentrations. The EC50 (based on inhibition biomass growth) was determined to be 19 mg/L. The EC50 (based on growth rate related inhibition) was determined to be 27 mg/L, the NOEC (based on biomass and growth rate) was determined to be 7.2 mg/L.
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