Registration Dossier
Registration Dossier
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EC number: 939-379-0 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Mice were treated with vehicle, 2 %, 10 % or 50 % Gelbpigment E4GN in DMF.
The NMRI mice did not show an increase in the stimulation indices for cell counts or for weights of the draining lymph nodes after application of the test item Gelbpigment E4GN.
The “positive level”, which is 1.4 for the cell count index, was never reached or exceeded in any dose group.
These findings were verified by the results obtained with the positive control compound Alpha Hexyl Cinnamic Aldehyde.
Migrated from Short description of key information:
A modified Local Lymph Node Assay (IMDS) indicate for up to and including a 50% suspension of Gelbpigment E4GN no sensitisation potential.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
no data
Migrated from Short description of key information:
no data
Justification for classification or non-classification
Due to the results of the LLNA a classification for skin sensitisation is not justified
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