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EC number: 237-438-9
CAS number: 13784-51-5
Four studies with aquatic organisms from
three different trophic levels are available; three acute endpoints and
two chronic endpoints.
One acute freshwater fish study with Danio
rerio, a semi-static test set up, according to OECD guideline 203 was
performed. A nominal concentration of 100 mg a.i./L did not cause any
effect. This test concentration was converted to measured TWA active
ingredient concentration as the test substance was not stable during the
96h-LC50 for fish is greater than 67.6 mg a.i./L (measured TWA), The
96h-NOEC is greater than or equal to 67.6 mg a.i./L..
acute freshwater invertebrate study with Daphnia magna, a static test
set up, according to OECD guideline 202 was performed. The test
substance was not stable during the tst and therefore the geometric mean
of the measured active ingredient concentrations is used.
48h-EC50 for aquatic
invertebrates is 7.1 mg a.i./L (measured geometric mean).
One chronic study with Daphnia magna
according to OECD 211 was performed. Exposure of Daphnia magna for 21
days to the test item resulted in significant mortalities at the
concentrations of 24 and 42 mg/L (equivalent to 7.1 and 12 mg a.i./L,
respectively) resulting in 100% mortality by Days 2 and 1, respectively.
The 21 Day EC50 and EC10 (immobilization)
value, based on the average measured concentration of the freshly
prepared test preparations, for the parental daphnia generation (P1)
were calculated to be 13 mg/L and 5.6 mg/L, respectively (equivalent to
3.9 mg a.i./L and 1.7 mg a.i./L).
The 21 Day EC50 and EC10 (reproduction)
based on the average measured concentration of the freshly prepared test
preparations were 19 mg/L and 15 mg/L, respectively (equivalent to 5.6
mg a.i./L and 4.3 mg a.i./L).
The NOEC and the LOEC based on the average
measured concentration of the freshly prepared test preparations were 14
and 24 mg/L, respectively (equivalent to 4.0 and 7.1 mg a.i./L).
One study with the freshwater alga species
Pseudokirchneriella subcapitata, a static test set up, according to OECD
guideline 201 was performed.The
test substance was not stable during the test and therefore measured TWA
active ingredient concentrations were used.
72h-ErC10 for freshwater algae
is 3.5 mg a.i./L (measured. TWA) and the 72h-ErC50 is 5.4 mg a.i./L
Toxicity to microorganisms was determined as
well in an activated sludge respiration inhibition test was performed
according to OECD 209.
The EC10 and EC50 (3h) of the substance for
activated sludge are 62 mg a.i./L and 182 mg a.i./L, respectively. The
substance is therefore considered harmless to activated sludge.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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