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EC number: 410-070-8 | CAS number: 141880-36-6 ACID RED HT 3728; ERIONYL RED HT 3728
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 10 June 1992 to 02 October 1992
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Product Designation: FAT 45155/B, (Erionyl Rot KT 3728)
Identification: Vers. Nr. TV 1 - Dissociating properties:
- yes
- No.:
- #1
- pKa:
- 8.02
- Temp.:
- 20 °C
- Remarks on result:
- other: acidic
- No.:
- #2
- pKa:
- 11.97
- Temp.:
- 20 °C
- Remarks on result:
- other: acidic
- No.:
- #3
- pKa:
- > -3 - < -2.5
- Temp.:
- 20 °C
- Remarks on result:
- other: acidic (estimated)
- Conclusions:
- Dissociation constant of FAT 45155/B is pKa1: 8.02; pKa2: 11.97.
- Executive summary:
A GLP-compliant study with FAT 45155/B was carried out according to OECD guideline 112. Based on the test results, the dissociation constants of the test material were determined to be pKa1 as 8.02 and pKa2 as 11.97.
Reference
As the test substance has extremely high pK value, it was not possible to obtain the adsorbance of the fully dissociated compound. The endpoints of titration was obtained by iteration using a LOTUS 123 speadsheet. The best estimation of the endpoint is then reached, when the pK values calculated form the individual measured points show the smallest deviation from each other.
The high measured pK value of 11.97 suggests that in the range pH>8 the compound is in the hydrazo form instead of the azo form.
Description of key information
A GLP-compliant study with FAT 45155/B was carried out according to OECD guideline 112. Based on the test results, the dissociation constant of the test material were determined to be pKa1 as 8.02 and pKa2 as 11.97.
Key value for chemical safety assessment
- pKa at 20°C:
- 8.02
Additional information
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