Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
basic toxicokinetics, other
Type of information:
other: Assessment, based on physico-chemical properties of the compound and on toxicological data. Experimental toxicokinetic studies were not performed.
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The assessment of the toxicokinetics is based on physico-chemical properties of the compound and on toxicological data. Experimental toxicokinetic studies were not performed.

Data source

Reference
Reference Type:
other: Toxicokinetic Assessment
Title:
Unnamed
Year:
2009
Report date:
2009

Materials and methods

Principles of method if other than guideline:
Assessment on toxicokinetics

Test material

Constituent 1
Chemical structure
Reference substance name:
4,4'-methylenedicyclohexyl diisocyanate
EC Number:
225-863-2
EC Name:
4,4'-methylenedicyclohexyl diisocyanate
Cas Number:
5124-30-1
Molecular formula:
C15H22N2O2
IUPAC Name:
1,1'-methylenebis(4-isocyanatocyclohexane)

Results and discussion

Any other information on results incl. tables

The following remarks on the toxicokinetics of 4,4´-methylenedicyclohexyl diisocyanate are based on physicochemical properties of the compound and on toxicological data. Experimental toxicokinetic studies were not performed.

Applicant's summary and conclusion