Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

The reported values for acute aquatic toxicity range from 2.36 mg/l (96hr EC50 for Algae - QSAR) to 7.72 mg/l (96hr LC50 for fish - measured).

These values do not indicate that 1,2,4-trimethylbenzene would meet the criteria for toxic in the PBT assessment. Also, these endpoint would not affect the classification of the 1, 2, 4-trimethylbenzene since the substance is biodegradable and the log Kow is < 4.0. However, under the harmonization of Annex 1 and GHS the substance has been classified as Aquatic Chronic 2 hazard to the environment and the hazard statement 'Toxic to aquatic life with long lasting effects'. This is because under Annex 1 the substance has been classified as N R51-53 because the log Kow criterion is > 3.0 for this classification. The log Kow of 1, 2, 4-trimethylbenzene is 3.63.