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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data is from authoritative database
Justification for type of information:
Data is from authoritative database
Qualifier:
according to
Guideline:
other: Refer below principle
Principles of method if other than guideline:
Aim of this study was to determine the long term effect of test chemical on the aquatic invertebrate daphnia magna for 21 days.
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
Daphnia magna
Details on test organisms:
- Common name: Water flea
Test type:
semi-static
Water media type:
freshwater
Total exposure duration:
21 d
Reference substance (positive control):
no
Key result
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
1.5 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
not specified
Remarks on result:
other: Other details not known
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.2 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
not specified
Remarks on result:
other: Other details not known
Validity criteria fulfilled:
not specified
Conclusions:
After the exposure of test chemical with daphnia magna, effect were observed and calculated. The EC50 value after 21 days of exposure were determine to be 1.5 mg/l and NOEC was at 0.2 mg/l.
Executive summary:

Aim of this study was to determine the long term effect of test chemical on the aquatic invertebrate daphnia magna for 21 days. After the exposure of test chemical with daphnia magna, effect were observed and calculated. The EC50 value after 21 days of exposure were determine to be 1.5 mg/l and NOEC was at 0.2 mg/l. Based on the EC50 value, chemical consider to be not toxic and not classified as per the CLP classification criteria.

Description of key information

Aim of this study was to determine the long term effect of test chemical on the aquatic invertebrate daphnia magna for 21 days. After the exposure of test chemical with daphnia magna, effect were observed and calculated. The EC50 value after 21 days of exposure were determine to be 1.5 mg/l and NOEC was at 0.2 mg/l. Based on the NOEC value, chemical consider to be toxic and classified aquatic chronic 2 as per the CLP classification criteria.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater invertebrates:
1.5 mg/L

Additional information

Aim of this study was to determine the long term effect of test chemical on the aquatic invertebrate daphnia magna for 21 days. After the exposure of test chemical with daphnia magna, effect were observed and calculated. The EC50 value after 21 days of exposure were determine to be 1.5 mg/l and NOEC was at 0.2 mg/l. Based on the NOEC value, chemical consider to be toxic and classified aquatic chronic 2 as per the CLP classification criteria.