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EC number: 950-627-7 | CAS number: 1042950-30-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Version / remarks:
- OECD 202 (13 April 2004)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Active substance: 100%
- Analytical monitoring:
- yes
- Details on sampling:
- Chemical analysis of the test item concentration in the test solutions was performed to determine exposure concentration and stability of the test item during exposure. Substance specific analysis was performed at an external test site.
The samples were filled into glass vials, stabilised with 50% Acetonitrile and stored in the freezer (≤ -18 °C). Sampling and documentation were conducted according to the following specification:
After 0 h, 24 h and 48 h exposure, two replicates of NC, A, B, C, D, E, F and G were sampled. At 24 h, both the 24 h old test solutions and the freshly prepared test solutions were sampled. Per replicate 1 ml of each test vessel of one treatment group was taken and pooled in one glass vial to obtain 4 ml in total. To each vial 4 ml Acetonitrile were added for stabilization and samples were stored in the freezer (≤ -18 °C).
Of each sampled treatment, one of the analytical samples from 0 h, 24 h old and new and 48 h was sent to the analytical laboratory at the external test site for chemical analysis using an insulated box with thermal packs. The remaining samples were stored as retain samples in the freezer (≤ -18 °C) until finalisation of the study.
In the control, the test item was not detected. The mean measured test item concentrations in the test item treatments were 99.1 – 110.5 % of the nominal concentrations. As the mean measured test item concentrations are within ± 20 % of the nominal concentrations, according to OECD 202 (2004) and OECD 23 (2000), all results are given in relation to the nominal test item concentrations. - Vehicle:
- no
- Details on test solutions:
- The pH was 7.9 – 8.3 in the control (required: pH 6 – 9) and 7.9 – 9.7 in the test item treatments.
The dissolved oxygen concentration was 8.2 – 8.5 mg/L in the control and 8.1 – 8.5 mg/L in the test item treatments.
The temperature during the exposure was 19.7 – 20.4 °C. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- The test organism Daphnia magna Straus originates from the clone breeding of the Federal Environment Agency, department IV 2.4, Berlin, and has been cultivated since October 2012. The daphnids are cultured at 20 +/- 2 °C with 16 h light : 8 h dark and placed into fresh Elendt M4 medium twice a week. They are kept at approx. 10 animals / 200 mL and fed on workdays with Desmodesmus subspicatus algae corresponding to 0.1 mg C × daphnid-1 × day-1.
The test organisms used were 1.25 - 22.75 h old at the start of the test. - Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Test temperature:
- The temperature during the exposure was 19.7 – 20.4 °C.
- pH:
- The pH was 7.9 – 8.3 in the control (required: pH 6 – 9) and 7.9 – 9.7 in the test item treatments.
- Dissolved oxygen:
- The dissolved oxygen concentration was 8.2 – 8.5 mg/L in the control and 8.1 – 8.5 mg/L in the test item treatments.
- Reference substance (positive control):
- no
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 65.34 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 27.85 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC10
- Effect conc.:
- 65.54 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Reference
The EC 50 was determined to be at 65.34 mg/L, based on mobility (72 h)
Description of key information
The EC 50 was determined to be at 65.34 mg/L, based on mobility (48 h)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- LC50
- Effect concentration:
- 65.34 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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