Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 945-910-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study performed under GLP. All relevant validity criteria were met.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7200 (Melting Point / Melting Range)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- thermal analysis
- Melting / freezing pt.:
- >= -58 °C
- Atm. press.:
- 1 atm
- Sublimation:
- no
- Remarks on result:
- other: mean result of two DSC determinations; thermal event was a glass transition temperature
- Conclusions:
- The melting temperature (glass transition temperature) was observed at – 58 °C (or 215 K). At this temperature the substance is considered to be liquid.
- Executive summary:
The melting/freezing temperature was determined using EU Method A.1 and OECD TG 102 - Differential Scanning Calorimetry. The guideline defines the melting temperature as: the temperature at which the phase transition from solid to liquid state occurs at atmospheric pressure and this temperature ideally corresponds to the freezing temperature. The glass transition was determined as the average glass transition temperature obtained from Experiment 1 (-58.14°C) and Experiment 2 (-57.30°C) and was determined to be -58°C (215K) by using DSC. Applicant assessment indicates the substance should be considered a liquid at temperatures in excess of - 20°C and/or at environmentally relevant conditions.
Reference
Main study
- Experiment 1: During cooling, a glass transition between -50°C and -90°C was observed (results are archived in the raw data). During heating a glass transition between -40°C and -75°C was observed. The inflection point of the glass transition was -58.14°C. Additionally, an unknown endothermic peak between 25°C and 50°C was observed.
- Experiment 2: To investigate the unknown peak between 25°C and 50°C a repeated heating cycle was applied also to yield a duplicate glass transition temperature. During first cooling a glass transition between -50°C and -90°C was observed. With the first heating a glass transition between -40°C and -75°C was observed. The inflection point of the glass transition was -57.30°C. An unknown peak was observed between 25°C and 65°C. During second cooling a glass transition between -50°C and -90°C was observed. With the second heating a glass transition between -40°C and -75°C was observed. This temperature was not used in the calculation. No endothermic effect was observed between 25°C and 50°C. After the experiment, a yellow molten residue remained in the sample container.
The glass transition was determined as the average glass transition temperature obtained from Experiment 1 (-58.14°C) and Experiment 2 (-57.30°C).
Description of key information
Mp: Glass transition temperature - 58°C (or 215 K) at 1 atm, substance is liquid, EU Method A.1 - Thermal Analysis Method, 2016
Key value for chemical safety assessment
Additional information
The melting/freezing temperature was determined using EU Method A.1 and OECD TG 102 - Differential Scanning Calorimetry. The guideline defines the melting temperature as: the temperature at which the phase transition from solid to liquid state occurs at atmospheric pressure and this temperature ideally corresponds to the freezing temperature. The glass transition was determined as the average glass transition temperature obtained from Experiment 1 (-58.14°C) and Experiment 2 (-57.30°C) and was determined to be -58°C (215K) by using DSC.
Applicant assessment of the DSC curve indicates: the substance appears to have constituents that possess amorphous solid properties at low temperatures (< 20 °C) and possesses a Glass Transition Temperature (Tg) analogous to the conventional ‘melting point’ as defined under the OECD TG 102 guideline. This is a temperature point where the substance possesses glass form as opposed to possessing super-cooled liquid form. Although the second thermal event at between 25°C and 65°C was not identified; it was clearly not boiling, evaporation or decomposition of the test item and would by expert judgement be considered to be a second thermal event where suspended amorphous solid within the bulk liquid undergoes a final supercooled-liquid to liquid transition. For hazard assessment the substance should be treated as a liquid. This is based on the bulk properties of the test item being clearly ‘liquid’ as defined in Regulation (EC) 1272/2008: Annex I, section 1.0. In that the substance is not gaseous and has a vapour pressure < 300 kPa at 50°C and/or has an ‘initial melting point’ at < 20°C. The test substance was also observed to flow as a liquid at temperatures between -20°C and up to 25°C. Therefore for hazard assessment purposes the substance should be considered a liquid at temperatures in excess of - 20°C and/or at environmentally relevant conditions.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.