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Diss Factsheets
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EC number: 909-044-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Additional information
There no data available on phosphonic ester residue with respect to toxicity to reproduction.
Phosphonic ester residue contains monomethyl phosphonate, phosphonic acid, and Dimethylphosphonate, and salt of pyrophosphoric acid. and phosphate which were not further specified
Phosphonic acid; Monomethylphosphonic acid; Pyrophosphoric acid:
There are no data availble with respect to toxicity to reproduction
DimethylphosphonateIn a screening study on rats according to OECD TG 421 (gavage study, 30, 90, 270 mg/kg bw), effects on fertility were seen in females at 270 mg/kg bw/day in the presence of severe general toxicity (decrease in number of females with corpora lutea and implantation sites) (NOAEL reproduction toxicity: 90 mg/kg bw/day; NOAEL general toxicity: 90 mg/kg bw/day). No developmental toxicity was found in rats at doses of 30 and 90 mg/kg bw (NOAEL developmentaltoxicity: 90 mg/kg bw/d).
Based on the study results and according to DSD-DPD and CLP classification criteria, the test substance is not to be classified.
Short description of key information:
There no data available on phosphonic ester residue with respect to toxicity to reproduction.
Effects on developmental toxicity
Description of key information
There no data available on phosphonic ester residue with respect to toxicity to developmental toxicity
Additional information
There no data available on phosphonic ester residue with respect to toxicity to reproduction.
Phosphonic ester residue contains monomethyl phosphonate, phosphonic acid, and Dimethylphosphonate, and salt of pyrophosphoric acid. and phosphate which were not further specified
Phosphonic acid; Monomethylphosphonic acid; Pyrophosphoric acid:
There are no data availble with respect to toxicity to reproduction
DimethylphosphitIn a screening study according to OECD TG 421 (Eiben R and Hartmann E, 2002) with male and female rats dosed up to 270 mg/kg bw, the sex ratio, mortality and weights of F1 pups were not affected by treatment up to and including 90 mg/kg bw/day, while evaluation was not possible at higher doses as there were no surviving pups. No externally malformed pups were observed.
Justification for classification or non-classification
based on the available data no classification/labelling is required.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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