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EC number: 418-310-3 | CAS number: 126050-54-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20 November 1995 to 08 December 1995
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study performed in accordance with OECD & EU test guidelines in compliance with GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes
- Type of method:
- column elution method
- Water solubility:
- < 0.59 mg/L
- Temp.:
- 20 °C
- pH:
- 7
- Details on results:
- Based on information supplied by the sponsor the water solubility was expected to be very low. Therefore, the column elution method was chosen for the performance of the water solubility study.
The HPLC method supplied by the sponsor was not suitable for the analysis of ADK STAB HP-10 in water (data not reported). In the chromatograms of the samples a lot of interfering peaks were observed with the same retention time as the test substance. Therefore, an UV/VIS spectrophotometric method was used for the analysis of ADK STAB HP-10 in water.
Extraction efficiency: No test substance was detected in the third extract of the sample which was extracted three times.
In the standard solution which was evaporated 98% of the original amount of test substance was found. Hence, no test substance was lost during the evaporation procedure.
Main study: The chromatograms of the samples taken from the blank column at 20.0 ± 0.5°C did not show a significant adsorbance between 260 and 280 nm.
The water solubility of the test substance was determined to be below the detection limit of column II.
In conclusion, the water solubility of ADK STAB HP-10 at 20.0 ± 0.5°C is <0.59 mg/l, using the column elution method. - Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of ADK STAB HP-10 in distilled water at 20.0 ± 0.5°C is determined to be <0.59 mg/l, using the column elution method. - Executive summary:
The determination of the water solubility was based on the following guidelines:
OECD guideline for testing of chemicals no. 105: "Water solubility (column elution method - flask method)", Adopted May 12, 1981.
EEC Directive 92/69 EEC, Part A, Methods for the determination of physicochemical properties, A.6: "Water solubility". EEC Publication no. L383, December 1992.
The water solubility of ADK STAB HP-10 in distilled water at 20.0±0.5°C is determined to be <0.59 mg/l, using the column elution method.
Reference
Table 1 – Results of the water solubility of ADK STAB HP-10 at 20.0 ± 0.5°C (Column I)
Flow rate [ml/h] |
Sample no |
Concentration analysed [mg/l] |
Mean1[g/l] |
Mean2 [g/l] |
pH |
12 |
1 |
<0.71 |
<0.71 |
<0.71 |
7.3 |
2 |
<0.71 |
||||
3 |
<0.71 |
||||
4 |
<0.71 |
||||
5 |
<0.71 |
||||
6 |
<0.71 |
||||
24 |
7 |
<0.71 |
<0.71 |
7.1 |
|
8 |
<0.71 |
||||
9 |
<0.71 |
||||
9 |
<0.71 |
||||
11 |
<0.71 |
1Mean value of all concentrations analysed at one flow rate.
2Mean value of the water solubilities of both flow rates.
Table 2 – Results of the water solubility of ADK STAB HP-10 at 20.0 ± 0.5°C (Column II)
Flow rate [ml/h] |
Sample no |
Concentration analysed [mg/l] |
Mean1[g/l] (CV) |
Mean2[g/l] (MD) |
pH |
12 |
12 |
<0.59 |
<0.59 |
<0.59 |
7.3 |
13 |
<0.59 |
||||
14 |
<0.59 |
||||
15 |
<0.59 |
||||
16 |
<0.59 |
||||
17 |
<0.59 |
||||
24 |
18 |
<0.59 |
<0.59 |
6.7 |
|
19 |
<0.59 |
||||
20 |
<0.59 |
||||
21 |
<0.59 |
||||
22 |
<0.59 |
1Mean value of all concentrations analysed at one flow rate.
2Mean value of the water solubilities of both flow rates.
Description of key information
Key value determined using EU Method A6 & OECD guideline 105.
Key value for chemical safety assessment
- Water solubility:
- 0.59 mg/L
- at the temperature of:
- 20 °C
Additional information
The water solubility of ADK STAB HP-10 in distilled water at 20.0 ± 0.5°C is determined to be <0.59 mg/l, using the column elution method.
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