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EC number: 418-310-3 | CAS number: 126050-54-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 01 November 1995
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study performed in accordance with OECD & EU test guidelines in compliance with GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- > 6.2
- Temp.:
- 24 °C
- Remarks on result:
- other: pH not detailed in the report
- Details on results:
- Based on the information supplied by the sponsor a high log Pow was expected. Therefore, the HPLC method was chosen for the performance of the main study.
In the HPLC chromatograms of ADK STAB HP-10, using detection at 275 nm, one test substance peak was observed. The retention time was 21.0 minutes. The retention time of 2,4-DDT was 2.1 minutes.
Hence, the retention time of the test substance peak was far beyond the retention time of the reference substance. Therefore, it was concluded that the partition coefficient (n-octanol/water) of ADK STAB HP-10 was > 1.6 10E6 (log Pow > 6.2) at room temperature. - Conclusions:
- The partition coefficient (n-octanol/water) of ADK STAB HP-10 was determined to be > 1.6 x 10E6 (log Pow > 6.2) at room temperature. The test was performed using the HPLC method.
- Executive summary:
The determination of the partition coefficient (n-octanol/water) was based on the following guidelines:
OECD Guidelines for Testing of Chemicals no.1D7: "Partition coefficient (n-octanol/water)", Adopted May 12, 1981.
OECD Guidelines for Testing of Chemicals, Guideline No. 117: "Partition coefficient (n-octanol/water) High Performance Liquid Chromatography (HPLC) method" (adopted March 30, 1989).
EEC directive 92/69 EEC, Part A, Methods for the determination of physicochemical properties, A.8: "Partition coefficient", EEC Publication no. L383, December 1992.
The partition coefficient (n-octanol/water) of ADK STAB HP-10 was determined to be>1.6 x 10E6 (log Pow>6.2) at room temperature. The test was performed using the HPLC method.
Reference
Description of key information
Key value determined using EU Method A8 and OECD Methods 107 & 117.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 6.2
- at the temperature of:
- 24 °C
Additional information
The partition coefficient (n-octanol/water) of ADK STAB HP-10 was determined to be>1.6 x 10E6 (log Pow>6.2) at room temperature. The test was performed using the HPLC method.
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